Majalah Obat Tradisional
Vol 24, No 1 (2019)

Potency of Black Soybean (Glycine max (L.) Merr) Extract and Daidzein as Antioxidant and Antihyaluronidase

Tandiah Asan (Master in Biomedical Sciences Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia)
I Nyoman Ehrich Lister (Master in Biomedical Sciences Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia)
Edy Fachrial (Master in Biomedical Sciences Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia)
Annisa Amalia (Aretha Medika Utama, Biomolecular and Biomedical Research Center, Bandung, West Java, Indonesia)
Wahyu Widowati (Faculty of Medicine, Maranatha Christian University, Bandung, West Java, Indonesia)
Buter Samin (Master in Biomedical Sciences Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia)
Liena Liena (Master in Biomedical Sciences Faculty of Medicine, Universitas Prima Indonesia, Medan, North Sumatera, Indonesia)



Article Info

Publish Date
30 Apr 2019

Abstract

Black soybean (Glycine max (L.) Merr.) is a plant that is widely planted and consumed in Indonesia. In addition, black soybean has unique content of isoflavones, such as daidzein, which is one of the active compounds that have the effect of fighting free radicals and can inhibit the aging process. The purpose of this study is to analyze the antioxidant potency possessed by black soybean extract (BSE) and daidzeinin inhibiting aging of the skin. The method used is a colorimetric test. The type of antioxidant test used is H2O2 scavenging and inhibiting the activity of the hyaluronidase enzyme for antiaging. BSE has better effectiveness of H2O2 scavenging (IC50: 286.24±11.16 (µg/mL)) than daidzein compound (IC50: 366.16±2.54 (µg/mL)). In the inhibition of hyaluronidase enzyme, the daidzein has more effective activities (IC50: 95.80±3.98 (µg/mL)) compared to BSE (IC50: 152.56±13.98 (µg/mL)). The antioxidant and anti-aging activities possessed by BSE make it possible to be used as a cosmetic ingredient for skin aging therapy.

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Journal Info

Abbrev

TradMedJ

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, ...