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INDONESIA
Jurnal Ilmiah Manuntung
Published by SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA
ISSN : 2443115X     EISSN : 24771821     DOI : -
Core Subject : Agriculture,
Agriculture, Biological Sciences & Forestry
Jurnal Media Pertanian dipublikasikan dalam Bahasa Indonesia dan diterbitkan dua kali dalam setahun. Jurnal ini mempublikasikan artikel hasil penelitian dan artikel review bidang ilmu Agronomi secara luas. Semua tulisan yang masuk hendaknya bukanlah hasil plagiat dan belum dipublikasikan. Artikel akan di review oleh editor dan hasilnya akan di komunikasikan dengan penulis.
Arjuna Subject : -
Articles 11 Documents
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Search results for , issue "Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung" : 11 Documents clear
OPTIMASI KARBOPOL DAN HPMC DALAM FORMULASI GEL ANTIJERAWAT NANOPARTIKEL EKSTRAK DAUN SIRIH (Piper betle Linn) Saryanti, Dwi; Nugraheni, Dian; Astuti, Nisa Sindi; Pertiwi, Natasya Intania
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (99.969 KB)

Abstract

Gel is a semisolid preparation that is clear, translucent containing active ingredients, can provide a cool effect on the skin and good spread of the skin. The use of gelling agent in gel formulations greatly affects the physical properties of the resulting gel preparations. HPMC is a gel forming material that is neutral and can form a clear gel and can maintain the viscosity of the resulting gel, while carbopol are easily dispersed in water and produce preparations with sufficient viscosity. The research conducted aims to determine the comparison of carbopol and HPMC in the optimal gel formula of betel leaf extract nanoparticles with Simplex Lattice Design method. The response used was pH, viscosity, spreadability, adhesion and antibacterial activity against Staphylococcus aureus. The results obtained by carbopol concentration of 80.9% and HPMC 19.1% was the optimal gel formula of betel leaf extract nanoparticle. Based on the verification, an insignificant difference was obtained between the predictions of the software and the results of the tests performed. This shows that the method used was valid or can be trusted.

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