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INDONESIA
JURNAL ILMU KEFARMASIAN INDONESIA
Published by Universitas Pancasila
ISSN : 16931831     EISSN : 26146495     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmu Kefarmasian Indonesia memuat tulisan ilmiah baik berupa naskah hasil penelitian maupun naskah konsep di bidang Kefarmasian. Diterbitkan setiap 2 (dua) kali dalam setahun yaitu pada bulan April dan Oktober.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue "Vol 5 No 2 (2007): JIFI" : 7 Documents clear
Prosentase Penggunaan Amoksisilin secara Rasional untuk Swamedikasi Salesma Rehana Rehana; Sri Sutji Susilawati; Iskandar Sobri
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

The high frequency of common cold self medication using amoxycillin should be given serious attention, while the percentage of its use should be known. Investigation was carried out by a cross sectional survey study using questionaire as primary data (containing indication, dosage, and duration of therapy) in several pharmacies in Banyumas and Purbalingga during four months since December 2006 until March 2007. Investigation was carried out using 85 samples, 69 addult (81 %) and 16 children (19 %). Rational use of amoxycillin consisted of 61 samples (71,76 % ) and irrational use 24 samples (28,24 %). Irrational use of amoxycillin was caused by irrational indication, but 100% rational use were observed based on dosage and duration of therapy.
Seleksi Mikroba Endofit Curcuma Zedoria dalam Memproduksi Senyawa Kimia Antimikroba Yoice Srikandace; Yatri Hapsari; Partomuan Simanjuntak
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

It is well known, that temu putih (Curcuma zedoaria Berg.), a rhizome of the Zingiberaceae, is oftenly used as medicine. In this connection, the potential secondary metabolites as anticancer and antimicrobes are produced by endophytic microbes in the plant. In this research, five endophytic microbes from the Curcuma zedoaria’s rhizome were fermented to produce compounds as antimicrobes.
Efek Antiplasmodium dari Ekstrak Etilasetat Kulit Batang Asam Kandis (Garcinia parvifolia) secara In Vitro Syamsudin Syamsudin; Budi Prasetyo; Antonius Antonius
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

This research was carried out to assess the antiplasmodic activity of six fractions from the aethylacetate extract of the stem barks of Garcinia parfivolia. The result showed that fractions C, D, and G were IC50 < 10 µg/ml, fraction E: IC50 24,19 µg/ml, and fraction F and H: > 100 µg/ml against a chloroquine resistant strain of P. falciparum FCR-3.
Formulasi Tablet Matriks Mukoadhesif Diltiazem Hidroklorida Menggunakan Hidroksi Propil Metil Selulosa dan Carbopol 940 Siti Sofiah; Faizatun Faizatun; Yulia Riyana
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Diltiazem hydrochloride has a half life of 3-4 hours and a bioavailability of 40%. The influence of a mixture of carbopol 940 and hydroxypropyl methyl cellulose as a mucoadhesive matrix on tablets made by the wet granulation method, had been determined by the dissolution and “wash off method. The result showed that increasing the concentration of carbopol 940 decreased the dissolution rate. The concentration of carbopol 940 and hydroxypropyl methyl cellulose in formula I (0%; 40%), II (5%; 35%), III (10%; 30%), IV (15%; 25%), and V (20%; 20%) released respectively 75,99%; 74,08%; 73,07%; 72,04%; and 71,29% diltiazem hydrochloride. The higher the concentration of carbopol 940 in acid solution, the shorter is the mucoadhesive action: 2 hours in formula I and II, and 1 hour in formula III, IV, and V. All of the formulas (pH 7,2) did not show a difference in mucoadhesive duration; after 8 hours, still attached to the mucosa of the small intestines.
Spektofotometri Derivatif dan Aplikasinya dalam Bidang Farmasi Liliek Nurhidayati
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Derivative spectrophotometry is a method for the simultaneous determination of drugs mixtures due to their overlapping spectra. Since the practical introduction of the concept of spectral data derivatization, the derivative spectrophotometry technique was applied. This review describes the theoretical and instrumental aspects of derivative spectrophotometry and some of its applications in pharmaceutical analysis since 1999.
Identifikasi Senyawa Flavonoid dalam Fraksi n-Butanol Taraxacum officinale, Asteraceae Wiwi Winarti; Ratna Djamil; Indah Yuniasari
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Herbs of Taraxacum officinale, a native of Europe, contain a flavonoid, steroid/triterpenoid, saponin, tanin, and a volatile oil. The purpose of this research was to determine the flavonoid substances, after partitioning of the methanolic extract by the Charaux-Paris method with n-butanol. Identification by uv-visible spectrophotometry confirmed that flavonoid from isolate la was a flavonol with an OH at 3, 7 position, oxygen at 6 or 8, while isolate III, also a flavonol, showed an OH at 3, 7 position, oxygen at 6 or 8, and besides that an additional o-diOH attached to ring B.
Potensi Pengembangan Industri dan Bioekonomi Berbasis Makanan Fermentasi Tradisional Suyanto Pawiroharsono
JURNAL ILMU KEFARMASIAN INDONESIA Vol 5 No 2 (2007): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Consumption of traditionally-fermented foods is around 25% of the total human food consumption. Indonesia has several important traditionally-fermented foods such as tempe (fermented soybean), tape (fermented cassava or glutinous rice), etc. Those foods are in general produced in smallscale industries or in home industries, which appear somewhat dirty, unhygienic and not standardized concerning its processing and the end product. The fermentation process benefits the improvement of its value: to preserve, to increase the nutrition value, flavor and taste as well as to produce a new product. Microorganisms play an important part in the fermentation process. The microorganisms involved in the traditionally-fermented food are usually a multiculture with a predominant strain. The microorganisms perform metabolic reactions and yield profit such as: (i) save to be consumed, (ii) easy to digest, and (iii) improving its nutritional and nutraceutical value, which are all advantageous for health. In addition, several traditionally-fermented foods also contain active substances potentially used for health, for preventing as well as for healing some diseases. The development of advanced biotechnology is to be expected in promoting the traditionally fermented food in favour of the food industry.

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