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Annik Megawati
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Cendekia Journal of Pharmacy
Published by Institut Teknologi Kesehatan Cendekia Utama Kudus
ISSN : 25992163     EISSN : 25992155     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Cendekia Journal of Pharmacy published by the Program Studi Farmasi STIKES Cendekia Utama Kudus with registered number ISSN 2599-2163 (Print) and for ISSN (Online) is 2599-2155. This journal is published twice a year, in November and May.
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Articles 12 Documents
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Search results for , issue "Vol 7, No 2 (2023): Cendekia Journal of Pharmacy" : 12 Documents clear
HUBUNGAN TINGKAT KEPATUHAN MINUM OBAT ANTIHIPERTENSI DAN OBESITAS TERHADAP TEKANAN DARAH PENDERITA HIPERTENSI Nur Islahuddin Aly; Annik Megawati
Cendekia Journal of Pharmacy Vol 7, No 2 (2023): Cendekia Journal of Pharmacy
Publisher : STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v7i2.250

Abstract

Hypertension is the most common disease that affects around 40% of the adult population worldwide and is called the silent killer. Compliance with taking prescription drugs is very necessary to avoid the risk of complications and minimize medical expenses. Improved adherence will provide maximum benefit from the prescribed medication and this is one simple strategy in the management of hypertension. Non- compliance with the use of anti-hypertensive drugs and obesity will be detrimental to the patient itself and is a factor that causes the failure of therapy being undertaken. The purpose of this study was to determine the relationship between the level of adherence to taking antihypertensive and obesity drugs to blood pressure in hypertensive patients. This type of research was observational analytic with cross sectional approach using total sampling of 67 respondents. The instruments used were questionnaires and calibrated instruments namely mercury sphygmomanometer, stethoscope and stature meter and digital scales. Statistical tests used Chi Square with a significance level of ? = 0.05 or 95%. Multivariate analysis using binary regression analysis. Obtained p value = 0,000 (p0.05) from the level of adherence to taking antihypertensive and obesity drugs to blood pressure in patients with hypertension. The magnitude of the influence of patients with hypertension who are obedient in taking high category drugs has a controlled blood pressure of 6,857 times compared to patients with obedient hypertension who take low medication. While the magnitude of the influence of patients with hypertension who are obese I have controlled blood pressure as much as 5,558 times compared to patients with obesity hypertension II. There is a significant relationship between the level of adherence to taking anti-hypertensive and obesity drugs to blood pressure in hypertensive patients
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN BAYAM HIJAU (Amaranthus hybridus L) DENGAN PEREDAMAN DPPH Yanulia Handayani; Ricka Islamiyati; Kadar Ismah; Dwi Susiloningrum
Cendekia Journal of Pharmacy Vol 7, No 2 (2023): Cendekia Journal of Pharmacy
Publisher : STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v7i2.244

Abstract

Bayam adalah tanaman yang termasuk dalam famili yang merupakan tanaman perdu dan semak.Manfaat dari daun bayam diantaranya dapat memperbaiki daya kerja ginjal, akarnya dapat digunakan untuk mengobati penyakit disentri dan mempercepat pertumbuhan sel. Bayam termasuk sayuran yang kaya nutrisi, dengan kandungan rendah kalori, namun sangat tinggi vitamin dan mineral.Bayam mengandung flavonoid berfungsi sebagai antioksidan yang dapat melindungi tubuh dari radikal bebas. Penelitian ini bertujuan untuk mengetahui kadar flavonoid total dan aktivitas antioksidan pada ekstrak etanol daun bayam hijau. Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol 70% dengan perbandingan 1:3. Penentuan kadar flavonoid total menggunakan pereaksi AICI3 dan uji aktivitas antioksidan menggunakan metode peredaman radikan bebas DPPH dengan menggunakan perbandingan kuersetin. Analis dilakukan dengan menggunakan alat spektrofotometri UV-Vis. Ekstrak etanol daun bayam mengandung kadar flavonoid total 6,893% dan memiliki aktivitas antioksidan dengan nilai IC50 sebesar 69,34 ppm. Ekstrak etanol daun bayam (Amarantus hybridus L) memiliki aktivitas antioksidan yang kuat.

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