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Mufid Febrianto
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CORD
Published by International Coconut Community
ISSN : 02151162     EISSN : 27218856     DOI : 10.37833/cord
Core Subject : Science, Agriculture,
Agriculture, Biological Sciences & Forestry Library & Information Science
Aims CORD aims to publish original research results and reviews on research and development. While encouraging those involved in research and developments to disseminate their finding it also assists policy makers and planners to be aware of the latest developments in the sector Scope CORD encompasses a broad range of research topics in animal sciences: seedlings and genetics, farming, harvesting, production, health, biotechnology, and production, socio-economic, and policy.
Arjuna Subject : Ilmu Pertanian dan Biologi (Semua) - Ilmu Pertanian dan Biologi (Lain-Lain)
Articles 6 Documents
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Search results for , issue "Vol 32 No 1 (2016): CORD" : 6 Documents clear
Effect of Virgin Coconut Oil Supplementation on Obese Rats’ Anthropometrical Parameters and Gut Bacteroidetes and Firmicutes Change Ratio Amadeus Driando Ahnan
International Coconut Community Journal Vol 32 No 1 (2016): CORD
Publisher : International Coconut Community

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (712.085 KB) | DOI: 10.37833/cord.v32i1.41

Abstract

Previous clinical trials using virgin coconut oil (VCO) showed a potential anti-obesity effect, including for human, by reducing the waist circumference. However, there was not discovered any research that examined its anti-obesity effect in relation with gut microbiota parameters as one of current approaches of obesity parameters, for example Firmicutes and Bacteroidetes. This research was conducted to examine the effect of VCO supplementation on the change of Firmicutes and Bacteroidetes in comparison to the anthropometrical parameters. The experiment was done using 14 days obese-induced female Sprague-Dawley rats supplemented with 0.01% w/w and 0.02% w/w VCO for 28 days. The anthropometric data collection consisted of body weight (BW), body mass index (BMI), abdominal circumference (AC), and body length (BL). Ratio changes in –fold increase between Day 28 and Day 0 of Bacteroidetes and Firmicutes were retrieved by using relative quantification normalized against unit mass calculation, using the cycle threshold values from real-time polymerase chain reaction (RT-PCR) method with SYBR Green fluorescence and standard curve derived from tenfold 5 points dilution series of recombinant plasmid for efficiency calculation. VCO supplementation stimulated significant increase on anthropometric parameters on BW and AC (p<0.05), while insignificant changes were shown on Bacteroidetes and Firmicutes ratio with tendency of increasing and decreasing respectfully, with no significance. The result indicated that VCO supplementation in the given doses promoted pro-obesity effect on key anthropometric parameters, while showed potential anti-obesity effect on the gut microbiota parameter. Further researches were needed especially in determining the effective dose to promote the anti-obesity effect of VCO and revealing any possible cellular and molecular mechanisms.
Preparation and Quality Assessment of Yoghurt Prepared from Dairy Milk and Coconut (Cocos nucifera, L) Milk S.R Priya
International Coconut Community Journal Vol 32 No 1 (2016): CORD
Publisher : International Coconut Community

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (588.848 KB) | DOI: 10.37833/cord.v32i1.42

Abstract

Yoghurt was produced using dairy and coconut milk. Five variants of yoghurt namely plain dairy and coconut yoghurt (variant I), dairy and coconut yoghurt with natural grape pulp (variant II), dairy and coconut yoghurt with synthetic grape flavour (variant III), dairy and coconut yoghurt with natural pineapple pulp (variant IV) and dairy and coconut yoghurt with synthetic pineapple flavour (variant V) were prepared. Among these five variants dairy and coconut yoghurt with pineapple pulp (variant IV) had received the highest mean scores for all the sensory criteria, and was selected for the further study. Physicochemical properties and selected nutrient components were analysed for the pineapple flavoured yoghurt prepared with dairy milk and coconut milk. Yoghurt made with coconut milk had scored higher values for all the analysed nutrients (energy - 142.49 ± 2.63, carbohydrate - 9.55 ± 0.12, protein – 8.02 ± 0.005 and fat – 13.03 ± 0.05) than yoghurt made with dairy milk (energy - 93.76±0.25, carbohydrate - 4.46 ± 0.05 , protein – 7.26 ± 0.11 and fat – 9.82 ± 0.02). The results of current study demonstrated that the addition of fruits to the yogurt significantly improved the product acceptability and also yoghurt produced from coconut milk can be a match able substitute for normal yoghurt.
Liposomal Drug Delivery of a Major Component of Coconut Oil for the Treatment of Acne Vulgaris in vitro and in vivo Dissaya Pornpattananangku
International Coconut Community Journal Vol 32 No 1 (2016): CORD
Publisher : International Coconut Community

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.371 KB) | DOI: 10.37833/cord.v32i1.43

Abstract

Abundantly found in coconut oil, lauric acid (LA), a 12-carbon atom chain free fatty acid, has shown its potent antimicrobial activity against the acne-causing bacteria, Propionibacterium acnes (P. acnes). To facilitate the administration of LA and improve its efficacy, nanoliposomes were used to encapsulate LA. In this study, the antimicrobial activity of LA was compared with other free fatty acids and benzoyl peroxide (BPO). Subsequently, LA was incorporated into nano-sized bilayer lipid vesicle (lauric acid liposome, LipoLA). It was demonstrated that the antimicrobial activity of LA in LipoLA was enhanced at low LA concentration. Interaction study also showed that the liposome aids in the fusion between LA and the bacterial membrane, leading to an effective delivery of LA molecules to the target site. More interestingly, in vivo study indicates that antimicrobial activity of LipoLA is well preserved and higher than BPO. Since LA is a natural compound from coconut oil and liposomes have been successfully and widely applied as a drug delivery vehicle in the clinic, the LipoLA developed in this work holds great potential of becoming a safe and effective therapeutic medication for acne vulgaris and other P. acnes associated infections.
Shelf Life and Quality Evaluation of Deep Frozen Coconut Cream, Coconut Scrapings and Coconut Slices K.D.P.P. Gunathilake
International Coconut Community Journal Vol 32 No 1 (2016): CORD
Publisher : International Coconut Community

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.222 KB) | DOI: 10.37833/cord.v32i1.44

Abstract

Coconut kernel is the major energy source in the diets of coconut producing countries. Ready to use coconut milk/kernel has a great demand in the market specifically for its nutty flavor. Studies were conducted to evaluate the storage quality of deep frozen coconut cream, scraped coconut and coconut slices. Coconut cream pasteurized and scraped coconut and coconut slices were blanched at 70 °C for 1.5 minutes. A known weight of each product was packed in nylon low density polyethylene, triple laminate and polyethylene and stored in a freezer at -18 °C. The shelf life was evaluated by free fatty acid content (FFA), peroxide value (PV) and total microbial load. The acceptability was tested using a triangle test with a 25 semi trained panelists in two weeks intervals for two months. FFA content increased during the storage period, but none of the products exceed the standard level of 1% The development of FFA in products packed in triple laminates was slow and peroxides were not detected up to 8 weeks of storage period. At the 8th week, microbial count reached to 106. Sensory study revealed that the organoleptic properties of all three coconut products were within the acceptable range though products showed differences sometimes, after 4 weeks storage compared with fresh samples. The results indicated that the minimum shelf life of the frozen coconut products is 8 weeks.
Coconut: Natural Source of Potential Anti Cancer Agent Dr. Amit Ghosh
International Coconut Community Journal Vol 32 No 1 (2016): CORD
Publisher : International Coconut Community

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (353.493 KB) | DOI: 10.37833/cord.v32i1.45

Abstract

The current strategy of drug development is time consuming and expensive. This contrasts sharply with the vision of affordable drug development. The costly and the lengthy paradigm of drug discoveries are major obstacles for combating with rapidly emerging and sporadic diseases. The dichotomy between the urgent requirement of affordable treatment development and the hindrance it faces is apparent in several recent literatures which reflects the importance of drug repurposing and development of botanical drugs. Consistent with this idea, past few decades of studies on Cocos nucifera has yielded a fair knowledge about the anticancer potential of coconut products. The aggregate knowledge is undeniably positive and offers the novel avenues for the therapeutics and affordable drug development. This article highlights the link between coconut products and its anticancer effects.
Virgin Coconut Oil for HIV - Positive People Dr. Kadek Dharma Widhiarta
International Coconut Community Journal Vol 32 No 1 (2016): CORD
Publisher : International Coconut Community

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.485 KB) | DOI: 10.37833/cord.v32i1.46

Abstract

The objective of the study was to determine effects of 3 x 15 ml/day Virgin Coconut Oil supplementation for 6 weeks in subject to CD4+ T lymphocyte concentration and conducted at Special health center on Dharmais Cancer Hospital, Jakarta. The methods involved experimental study with parallel design on 40 HIV subject with CD4+ T lymphocyte count > 200 cell/µL divided into two groups, VCO group, subject in this group received VCO supplementation 3 x 15 ml/day for 6 weeks and non-VCO Group (without VCO supplementation). Data collected includes demographic characteristic (age and sex), anthropometric (weight, height, and body mass index), daily intakes by food recall 1 x 24 hours and laboratory (CD4+ T lymphocyte count). Statistical analysis was performed with independent t test and Mann-Whitney U test. The results could be summarised as follows. The average BMI were 20.8 ± 2.29 kgs/sqm (VCO group) and 20.7 ± 3.38 kgs/sqm (non-VCO group). Energy and fat intake between VCO group (1459 ± 327.4 Cal/day and 81.8 ± 19.35 gs/day) and non-VCO group (1101 ± 319.8 Cal/day and 37.1 ± 19.35 gs/day). Carbohydrate and protein intake between VCO group (143.8 ± 44.58 gs/day and 41.6 ± 14.04 gs/day) and non-VCO group (151.6 ± 14.04 gs/day and 39.5 ± 18.31gs/day). There were significant differences (p = 0.047) in average of CD4+ T lymphocyte count after 6 weeks intervention between VCO group (481 ± 210.0 cell/µL) and non-VCO group (343 ± 129.1 cell/µL). The conclusion is that Virgin Coconut Oil supplementation 3 x 15 ml/day for 6 weeks increases CD4+ T lymphocyte concentration in HIV patient.

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