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Tropical Health and Medical Research Journal
Published by Baiman Bauntung Batuah Center
ISSN : -     EISSN : 2684740X     DOI : https://doi.org/10.35916/thmr.v1i1
Core Subject : Religion, Health, Science,
Religion Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Tropical Health and Medical Research is an open access, peer-reviewed journal that publishing only original research on all aspects of tropical medicine and global health especially health related to the Muslim community. Journal content including viral, bacterial and parasitic infectious diseases, Vectors, Noncommunicable diseases, Epidemiology and population health, Drug, vaccine and diagnostic tool development, Other health issues related to the Muslim community
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 58 Documents
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Utilization of Natural Dyes Solutions and Glycerol for the Quality and Durability of Direct Wet Mount Preparations Storage in Educational Laboratories Iswiyanti Novita; Linda Yuliana
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.65

Abstract

Educational laboratories require the availability of direct wet mount preparations that can last a long time with good quality. Various studies have mentioned techniques so that preparations can last a long time. This study aims to analyze the composition of dyes and glycerol in wet preparations of worm eggs on the quality and shelf life of the preparations. The solvent variations used for the wet preparations were Angkak 2%, and eosin 2%, with the addition of variations in the concentration of glycerol 20%-45%. The number of treatments and repetitions in the study was 70 samples, which were observed in the first, second, third, and fourth weeks. Based on the ANOVA test, the results showed a significant effect on the parameters measured, namely the type of dye, the type of slide, and the shelf life of the preparation (storage) in natural dye solution (2% ethanol extract of Angkak solution) and synthetic dye solution (2% eosin solution). The correlation test results of storage time treatment on the clarity of the preparations showed that the longer the storage, the lower the clarity of the preparations (r=-0.46246). The correlation test results of storage time treatment on the contrast of the preparations showed that the longer the storage, the less the contrast was not so strong (r=-0.26375). The correlation test results of storage time treatment on the quality of the preparations showed that the longer the storage, the lower the quality of the preparations (r=-0.51346). The conclusion is that the best quality of wet preparations is preparations that are stored for four weeks using a flat object-glass with a mixture of 1:1 dye solution of 2%-glycerol solution of 35% and 1:1 mixture of a 2%-glycerol solution of 1:1 solution. Further research is needed on the concentration of the dye solution mixture to find the best formulation for improving the quality and resistance of wet preparations.
Analyzes of Knowledge, Attitude, and Practice of Turkish Midwives and Puerperal Women Regarding Pharmacovigilance Yusuf Ergün; Eylem Toker; Mine Akben; Tansel Bekiroğlu Ergün
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.67

Abstract

Spontaneous reporting of adverse drug reactions (ADRs) is the backbone of the pharmacovigilance system. However, underreporting is still a fundamental hurdle around the globe that must be resolved. To analyze Turkish midwives' and puerperal women's knowledge, attitude, and practice regarding pharmacovigilance. A cross-sectional study on midwives (n=36) and puerperal women (n=227) was carried out from September 2019 to June 2020 in a State Hospital in Turkey. Data were collected by a questionnaire and analyzed by Mann-Whitney U, Kruskal-Wallis, and the Chi-Square tests. The knowledge level of midwives was significantly higher than that of the puerperal women. Although all midwives knew of adverse drug reactions, only half of the puerperal women had heard this. The awareness of the pharmacovigilance term was 97% and 2% in midwives and puerperal women, respectively. Similarly, 81% of the midwives were aware of the Turkish Pharmacovigilance Center (TPC), whereas only 1% of the puerperal women realized the fact. More than half of the midwives knew they could directly report ADRs to TPC. However, most did not know how they could send or report ADRs. Interestingly, only five midwives knew that congenital anomalies and congenital disabilities had been included in ADRs. Although the knowledge, attitude, and practice of Turkish midwives were significantly better than puerperal women regarding pharmacovigilance, it is apparent that both groups were insufficient to get involved in the pharmacovigilance system properly.
Comparison of Survival Rates of Syrian Refugee Versus Turkish Pediatric Patients with Leukemia Özlem Terzi; Cengiz Bayram; Ali Ayçiçek; Şadan Hacısalihoğlu; Hüseyin Avni Solgun; Tuba Nur Tahtakesen; Esra Esra Arslantaş; Gül Nihal Özdemir; Sibel Tekgündüz
Tropical Health and Medical Research Vol. 5 No. 1 (2023): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.68

Abstract

Although survival rates are increasing in acute leukaemias today, this rate is lower in developing countries; there are very few studies conducted on this matter in refugee patients. This research aims to evaluate the survival rate in pediatric Syrian refugee patients with acute leukaemia and compare it with Turkish pediatric leukaemia patients. A total of 144 patients diagnosed with acute leukaemia were included in the study, and their files were reviewed retrospectively. Nineteen 144 patients (13%) were Syrian refugees, and 125 (87%) were Turkish patients. The median age of the Syrian refugees and Turkish patients was 6.9 years (range 1-18 years) and 7.2 years (range 2-18 years), respectively, and gender distribution was similar for both groups (p:0.32). The relapse rate and rate of patients in the high-risk leukaemia group were higher in the Syrian refugee patient group (p=0.05). The survival rates of the Syrian refugee patients at the 11th month and 23nd month of the follow-up were 87.5% and 70%, respectively. The survival rates of the Turkish patients in the 23rd month and 44th month of the follow-up were 96.6% and 85%, respectively. The survival rates of the Turkish patients were significantly higher (p<0,001). The odds ratio of mortality adjusted for being a Syrian refugee was 5.3 (with a 95% confidence interval, 1.5 to 18.3). No difference was observed between the groups regarding compliance with treatment. Survival rates of the Syrian refugee leukaemia patients were lower, and the rate of patients in the high-risk leukaemia group and the relapse rate was higher in Syrian refugee patients compared to Turkish patients.
Another Reason for Vaccine Hesitancy in Turkey: Siblings with Autism Spectrum Disorder Semra Bayturan; Nesrin Şen Celasin
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i2.69

Abstract

Despite studies showing no link between the measles-mumps-rubella vaccine and autism spectrum disorder (ASD), the belief that the vaccine causes autism can still affect parents' attitudes towards vaccines. This study aimed to investigate the vaccination status, vaccine information source, and the factors related to vaccine hesitancy diagnosed with ASD and their younger siblings based on interviews and questionnaires. A questionnaire was performed on 37 ASD groups (parents of children with ASD and their younger siblings) and 65 control groups (families with healthy children and healthy younger siblings). The research was conducted between 1st January 2019 and 31st December 2019. Incomplete vaccination was found higher in both children with ASD(n=37) and their younger siblings compared to the healthy control group(n=65) (p=0.045; p=0.016). The four children (10.8%) diagnosed with ASD had five siblings with incomplete or missing vaccinations. Families with children with ASD stated that their knowledge of vaccines was sufficient compared to the control group (p=0.021). All parents stated the autism vaccination relationship as the reason for incomplete vaccination. Parents of children with ASD may delay or reject vaccination for their children and their younger siblings.
Seroprevalence of Leptospirosis in Suspected High-Risk Sudanese Patients; A Pilot Exploratory Study Nada Abdelghani Abdelrahim; Wisal Mustafa Ibrahim Mohammed
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i2.71

Abstract

The extent of leptospirosis is unknown in Sudan, and it might be mistaken for other more common febrile infectious diseases. Leptospirosis might also be associated with renal diseases that are common in Sudan. We intended to explore the existence of human leptospirosis in suspected high-risk patients in Khartoum, Sudan, via sero-screening random febrile patients and those undergoing renal dialysis. This pilot exploratory study was conducted over six months, from April to September 2013. Four hospitals were selected conveniently following a non-random sampling approach. One hundred nineteen febrile patients (with or without definitive diagnosis) and patients under renal dialysis were included, and their serum specimens and clinical and demographic data were collected. Sera were screened qualitatively for the existence of anti-leptospiral IgM antibodies using a rapid lateral flow immune-sorbent assay. Ethical clearance and official permissions were obtained. Of the 119 patients, 57 (47.9%) had end-stage renal disease. They were under dialysis at Renal Dialysis Unit in Asbab Charity Hospital in Bahri, 47 (39.5%) were febrile with unknown origin attending the Tropical Medicine Hospital in Omdurman, and 15 (12.6%) were febrile and were diagnosed as having malaria or typhoid and attended Yastabshiron Medical Centre and Bashauer Teaching Hospital. The prevalence of anti-leptospiral IgM antibodies among all 119 screened patients was 7%. The prevalence among the 57 with the end-stage renal disease was 9%, and among the 47 with a fever of unknown origin was 6%. The prevalence among the 15 with a fever of known origin (diagnosed as malaria or typhoid) was 0%. Almost all positive patients had recurring episodes of fever, were in close contact with livestock, were farmers, and had an untreated natural source for drinking water. Human leptospirosis does exist in this targeted population. It is probably a common febrile condition and can be easily considered one of the major causes of chronic kidney disease affecting people in Sudan. A national sero-screening for leptospirosis among those living in high-risk geographical areas and those at occupational risk is highly recommended.
The Covid-19 Disease in Pediatric Cancer Patients: A Single Center Experience Özlem Terzi; Hüseyin Avni Solgun; Nuran Karabulut; Sibel Tekgündüz; Fatma Sek; Cengiz Bayram; Ali Ayçiçek
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i2.73

Abstract

Children with cancer can have a severe disease when infected with respiratory viruses. In this study, we aimed to understand the clinical course and outcomes of SARS-CoV-2 infection in children with cancer. Data evaluated about laboratory-confirmed SARS-CoV-2 infections in sixty-three children (<18 years) with cancer between 01.06.2020 - 01.08.2021 were retrospectively reviewed. Data for demographics, oncological diagnosis, clinical course, and cancer therapy details were collected. Primary outcomes were disease severity and modification to cancer-directed therapy. The median (range) age was 7.6 ± 5.3 (0-18) years, and the most common underlying diagnosis was leukemia (74.6%). The most common symptom was fever (67.7%), and most patients had symptoms (70%). The mild disease was most common (60.3%). During Covid-19 infection, disease severity increased 23 times (p=0.003) in those with fever and 4.083 (p=0.045) in those with neutropenia. It was observed that the severity of the disease increased 2.589 times as CRP increased (p<0.001). However, few patients (9.5%) were admitted to the intensive care unit. Five patients died, but none of the deaths could be attributed to Covid-19 alone. Most patients did not experience chemotherapy treatment interruption (57%). When interruption did occur, this duration was 13.9±14.3 (1.0-60.0) days. In this cohort of pediatric oncology patients, nearly 43% of patients who had Covid-19 were their chemotherapy interrupted. Future studies will only reveal the final effect of the pandemic on childhood cancer.
Factors Affecting Clinical Course and Mortality among COVID-19 Patients Receiving Convalescent Plasma Treatment Ufuk Sonmez; Sabri Atalay; Hilal Abakay; Derya Çağlayan; Alpay Arı; Hüseyin Özkarakaş; Esra Uğur
Tropical Health and Medical Research Vol. 5 No. 1 (2023): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.74

Abstract

In this study, our research objectives are; to evaluate death risk covariates and the clinical course of the COVID-19 patients who had received convalescent plasma treatment. This study was performed between April 2020 -April 2021, retrospectively. The study was conducted at two centers in Izmir, Turkey. Demographic characteristics, number of plasma given, the time between the onset of the symptoms and the first plasma treatment, and laboratory results(C-reactive protein, white blood cell, thrombocyte, lymphocyte counts, D-dimer, alanine aminotransferase, aspartate aminotransferase, and procalcitonin) are recorded. Biochemical parameters and the necessity of oxygen support for the patients were evaluated on days 0, 3, and 7 of the first plasma treatment. Death risk covariates were analyzed. Described as moderate, severe, and critical, 199 patients were included in this study. The patients' mean age of the patients was63.7±14.2 (min:24-max:93). Most patients were in the severe group (41.7%). The frequency of necessity of non-invasive mechanical ventilation/mechanical ventilation (NIMV/MV) support on day three and day seven was lower than on day 0 (p:0.004). C-reactive protein and procalcitonin levels were progressively decreased on day three and day 7 (p<0.001, p<0.001).Multivariate analysis showed that; ?65 years of age (HR:1.62 [1.06–2.49]),critical disease severity(HR:2.64 [1.10–6.30]), necessity of corticosteroid treatment (HR:2.22 [1.29–3.82]), leukocyte counts of ?4.23x103/UL (HR:2.10 [1.19–3.69]), lymphocyte levels of ?0.80 x103/UL (HR:1.74 [1.06–2.86]), AST levels of ? 50 U/L (HR:2.18[1.42–3.34]), and procalcitonin levels of  ?0.5 ng/ml (HR:1.91 [1.26–2.91]) on day 3 were found independently associated with mortality. As a result, being older than 65 years old, having acute disease, receiving corticosteroids, having low lymphocyte-leucocyte counts, and having high ALT and procalcitonin levels are associated with mortality. Considering our findings, we think that more studies are needed in the patient groups.
Evaluation of the Laparoscopic Cystectomy for Endometrioma in Women of the Reproductive Age Sule Atalay Mert; Berna Dilbaz; Caner Kose; Yaprak Engin Ustun
Tropical Health and Medical Research Vol. 5 No. 1 (2023): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.75

Abstract

Aim of the study is to evaluate the pregnancy outcome and recurrence of the disease in patients with endometrioma. All patients who underwent laparoscopic surgery for endometrioma between January 2017- 2020 in Etlik Zubeyde Hanim Women Health Training and Research Hospital, had a stage 3-4 disease, and met the inclusion criteria were evaluated. The exclusion criteria were; being menopausal, having laparotomy for endometrioma surgery, or presence of concomitant leiomyoma. The post-operative reproductive outcome and the recurrence rate were evaluated. Out of the 97 patients recruited, 57 (58.8%) were followed up for infertility, while the remaining forty had no desire for future pregnancy. Sixty-seven patients had elective surgery, and 30 (30.9%) underwent emergency surgery. Pregnancy was achieved in 18 (31.5%) within 3-18 months (8.94±4.54) after surgery, of which seven (38.8%) were spontaneous pregnancies while 11 had pregnancy through assisted reproductive techniques. The live birth rate was 88.8%, thirteen term delivery. Out of 97 patients, only four (4,1%) had recurrent endometrioma. The total pregnancy rate was high in the secondary infertile group (44.8%-17.8%), and the IVF pregnancy rate (60%) was high in the primary infertile group. Endometrioma surgery can be recommended for selected patients while preserving ovarian tissue.
Utilization of Alternative Buffer Solutions for Staining Thin Blood smears by the Giemsa, Wright stain and Romanowsky method Neni Oktiyani; Ahmad Muhlisin; Erfan Roebiakto; Wahdah Norsiah; Mahpolah Mahpolah
Tropical Health and Medical Research Vol. 5 No. 1 (2023): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.76

Abstract

To make a reliable diagnosis on haematological examination, it is necessary to examine further the morphology of the blood cells previously stained in the procedure for staining thin blood smears using a buffer solution with a standard pH of 6.4 to 6.8. One of the problems that may occur in the laboratory is that the buffer reagents are damaged, past the expiration date or running out, so alternative buffers are needed that are cheap, fast and easy to obtain. This study aims to evaluate the staining results from alternative buffers. Study used a quasi-experimental method, and using alternative buffers from bottled mineral water following SNI-01-0553 2006. The colour produced by some of these alternative buffers is almost equivalent to blood cells stained with phosphate buffer. The percentage of assessment results in the alternative buffer codes B, C, D, E and F compared with control (A) were 62.67%, 92.00%, 82.67%, 80.00% 88, 00%, and 68.00%. The use of alternative buffers for staining thin blood smears using the Giemsa, Wright stain, and Romanowsky method can be done with mineral water as an alternative buffer for sample codes C, D, E and F, while B and G cannot be used. This alternative buffer can be applied by laboratory personnel in urgent situations in limited equipment and material facilities.
Evaluation of the Relationship Between Internet Addiction and Communication Competence Levels of Nurses Sevgi Kizilci Oz; Nese Kiskac; Muharrem Kiskac
Tropical Health and Medical Research Vol. 5 No. 1 (2023): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.77

Abstract

The purpose is to determine the evaluation of the relationship between internet addiction and the communication competence levels of nurses. This descriptive study was conducted with 347 nurses in a Training and Research Hospital in Turkey. Data were collected with the Communication Competence Scale and the Internet Addiction Scale. In the evaluation of the data, the IBM SPSS statistics 22.0 program was used for statistical analysis in the study. At the same time, they were evaluating the study data in addition to descriptive statistical methods. Pearson correlation analysis was used to evaluate the correlation between variables. Internet addiction and communication competence are, respectively, found to be 45.22±14.16 and 98.64±18.98. A negative and weak significant relationship (r=-.270; p?.05) was found between internet addiction and communication competence levels. The study determined that as the level of internet addiction among nurses increased, their communication competence decreased. Therefore, awareness of the effect of internet addiction on occupational functions is essential.

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