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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)

jetromi
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Published by TALENTA PUBLISHER

ISSN : 26860872 EISSN : 26860856 DOI : 10.32734

Core Subject : Health, Science,

Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.

Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme

Articles 6 Documents

Search results for , issue "Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)" : 6 Documents clear

Relationship Between Staging and Carcinoembryonic Antigen Serum Levels In Colorectal Cancer Patients' Chandra Agusrly; Taufik Sungkar; Gontar Alamsyah Siregar
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

The staging can be used as one of the prognostic factors providing a clinical picture of the patient in the future in colorectal cancer patient. In addition, carcinoembryonic antigen (CEA) as tumor markers can determine the commonly used diagnosis and prognosis of colorectal cancer. Objective: The aims study was to investigate the relationship of the staging and carcinoembryonic antigen serum levels in colorectal cancer patients. Methods. This was an analytical study with a cross-sectional design. The sample used was colorectal cancer patients at H. Adam Malik General Hospital, Medan from January 2016 to December 2018. As many as 52 subject study who met the inclusion and exclusion criteria. The Kruskal-Wallis test was used to determine relationship between staging and CEA serum levels. Results: The median value of carcinoembryonic antigen levels in Stage I, II, III, and IV group was (2.74 ng/ml vs 6.16 ng/ml vs 2.52 ng/ml, vs 26.87 ng/ml; p=0.003) respectively. Conclusion: There was relationship between staging and carcinoembryonic antigen serum levels in colorectal cancer patient

Correlation of Platelet Distribution Width (PDW) and Troponin I in Acute Myocardial Infarction Maulinda Putri -; Refli Hasan; Rahmad Isnanta
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background. Coronary artery disease (CAD) is caused by narrowing of the coronary arteries. In the event of acute myocardial infarction (AMI), there will be an increase in heart markers. Several studies have examined the relationship between Platelet Distribution Width (PDW) and AMI, but there is no specific correlation with troponin as the most sensitive and specific cardiac biomarker for AMI. This study aims to see the correlation PDW values with troponin I in patients with AMI. Method. This study was a cross-sectional method to determine the correlation of PDW variable values with troponin I in patients with AMI. In this study, the sample consisted of 64 people. Results. There is a moderate correlation between PDW and troponin I (r2= 0.72, p <0.001). There is a strong correlation with positive direction between PDW and Troponin I in patients with AMI based on the onset of chest pain (<6 hours and > 6 hours : r2 = 0.647 p <0.001and r2 = 0.756, p <0.001). Conclusion. Platelet Distribution Width (PDW) is strongly correlated with Troponin I in patients with AMI, and based on chest pain onset also has a significantly positive correlation.

Fibroblast Growth Factor-23 (FGF-23) in Patients with Regular Hemodialysis: A Risk Factor for Restless Legs Syndrome Rasyidah Hasan Harahap; Riri Andri Muzasti; Alwi Thamrin Nasution
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: Restless Legs Syndrome (RLS) is one of the most common sleep disturbance problems in dialysis patients. In this study, we would like to explore some of bone and mineral marker disorder especially fibroblast growth factor-23 (FGF-23)and its correlation with RLS in regular hemodialysis patients. Methods: This is a cross sectional study design involving 71 respondents with chronic kidney disease that already had regular hemodialysis at Haji Adam Malik Hospital Medan. Status of RLS in this patients were being evaluated according to the International Restless Leg Syndrome Study Group (IRLSG) by interviewing and laboratory examination of FGF-23, hemoglobin (Hb), serum iron (SI), total iron binding capacity (TIBC), transferrin saturation (TSAT), serum ferritin, calcium (Ca) and phosphate (P) level. Results: Of all study subjects, 26 respondents (34.6%) diagnosed with RLS. Bivariate analysis result showed that there is a relationship between FGF-23, hemoglobin, phosphate, and transferrin saturation level with RLS. Logistic regression analysis used to see the most dominant factor of all. Conclusion This study conclude that increase in FGF-23 levels can increase the risk of RLS. However, FGF-23 is not the most dominant risk factor for RLS in regular hemodialysis patients.

Case Report: A Confirmed COVID-19 Patient with Type 2 Diabetes Mellitus Annisa Nidya Sitepu; Santi Syafril
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

COVID-19 is caused by a novel coronavirus known as SARS-CoV-2, a single chain RNA virus with a particle size of 120-160 nm. Covid-19 can affect almost all age groups, despite, the elderly and people who have records of chronic disease (co-morbid) have the risk to be affected more often and with worse complications from this disease. Diabetes mellitus (DM) is one of the risk factors for enhancing the severity of COVID-19 infection. A 26 years old man, was referred to the hospital with symptoms of shortness of breath, fever, and cough. The patient has no history of comorbidities, but his father has newly type-2 diabetes mellitus (T2DM). The patient was examined, with ad random blood sugar of 220 mg/dL and a chest radiograph suggesting bronchopneumonia. The patient was then examined for fasting and postprandial glucose, HbA1c, and diagnosed with DM, the patient's throat swab showed a positive COVID-19 result. Patients were then treated with antiviral, antibiotic, regulated insulin, and his blood sugar was monitored. The patient's blood sugar is stable and the patient discharge after 34 days of hospitalization.

Effect of Salam leaf extract (Syzygium Polyanthum) to serum IL-10 levels on Acute Coronary Syndrome in Wistar Strain Mice Model Yulisa Astari Tanjung; Refli Hasan; Rahmad Isnanta
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background Coronary Heart Disease (CHD) is one of the leading causes of death in developed and developing countries. Syzygium polyanthum leaf (daun salam) are reported to have anti-inflammatory, antioxidant, antidiabetic, antimicrobial, antihypertensive, antitumor, antidiarrheal, acetylcholinesterase inhibition, and lipase inhibitory activity. The purpose of this study was to prove the effect of bay leaf extract (Syzygium polyanthum) on serum interleukin (IL)-10 levels in the heart of Wistar Strain Mice Model of Acute Coronary Syndrome (ACS). Methods This is an experimental study to compare the IL-10 level in 32 ACS mice which were divided into 8 groups. Serum IL-10 values were collected and analyzed according to the corresponding group with and without bay leaf extract administration, on day 1,4,7, and 14. Result: There is an IL-10 value increasing with the duration of examination following the onset of ACS induction. The highest average IL-10 value was found on the 14th day, in the two groups. On the same day, it was seen that the treatment group had a higher IL-10 value compared to the control group (p<0.001). The result showed that the concentration of IL-10 was significantly greater among the treatment group, which reveal the potential benefit of bay leaf extract in patients with ACS. Conclusion: There was found a significant difference of serum IL-10 between Wistar Strain Mice Model of ACS that was given S. polyanthum leaf extracts. S. polyanthum leaf extract has quite extensive benefits in the cardiovascular system.

Association of Neutrophil Lymphocyte Ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) Scores in Acute Coronary Syndrome Baginda Yusuf Siregar; Refli Hasan; Rahmad Isnanta
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background. Inflammation plays an important role in the initiation of atherosclerosis from the beginning of plaque to rupture cause Acute Coronary Syndrome (ACS). Neutrophil Lymphocyte Ratio (NLR) indicator of systemic inflammation in ACS. Risk stratification was needed for assessment and selection of initial invasive strategies and find the best strategy in ACS. The Global Registry of Acute Coronary Events (GRACE) scores recommended risk stratification of ACS. Aims of the study to determine the association and cut-off value NLR with risk stratification GRACE score. Method. This study is analytical with a cross-sectional retrospective design. Data were analyzed after distribution test, then mean difference and correlation test was using the SPPS program where p <0.05 was considered statistically significant. Results. This study showed significantly higher NLR value in the high risk stratification and intermediate-risk compared to low risk stratification (7.9 ± 2.7 vs 3.6 ± 1.7; p=0.001) (5.2 ± 2.3 vs 3.6 ± 1.7; p=0.018). Significant correlation between NLR with GRACE scores (r=0.570; p<0.001). Significant AUC values were obtained (0.782, p <0.001, IK95% 0.674-0.89), and cut-off values NLR 4 with sensitivity (78.8%) and specificity (70.3%) on the GRACE score. Conclusion. The significant association between NLR with GRACE risk score in ACS.

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Dharma Lindarto

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Dharma Lindarto

Contact Email jetromi@usu.ac.id

Phone +6282168842564

Journal Mail Official jetromi@usu.ac.id

Editorial Address Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

Location Unknown, Unknown INDONESIA

Abstract

Abstract

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Abstract

Contact Name
Dharma Lindarto

Contact Email
jetromi@usu.ac.id

Phone
+6282168842564

Journal Mail Official
jetromi@usu.ac.id

Editorial Address
Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

Location
Unknown,

Unknown

INDONESIA