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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)

jetromi
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Published by TALENTA PUBLISHER

ISSN : 26860872 EISSN : 26860856 DOI : 10.32734

Core Subject : Health, Science,

Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.

Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme

Articles 6 Documents

Search results for , issue "Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)" : 6 Documents clear

Correlation between Neutrophil to Lymphocyte Ratio (NLR) and D-Dimer In Patients Covid-19 with Diabetes Dharma Lindarto; Fransiscus Ginting
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.10318

Abstract: Background: The neutrophil to lymphocyte ratio (NLR) has been proposed as an infammatory biomarker. Tujuan penelitian adalah menilai hubungan antara NLR dan D-dimer pada pasien Covid-19 dengan diabetes. Method: This is a retrospective descriptive and analytical study carried out at NLR, blood rutin and D-dimer, FPG, and PPG levels of COVID-19 patients with comorbid in H. Adam Malik Medan, Indonesia, from May 19, 2020, to Juny 08, 2021. The data were collected by cheek list, using electronic medical records. The data included age, gender, medical history, comorbidity with diabetics, and ward and ICU admission. All these cases of COVID-19 have been confirmed in the laboratory by Real-Time Reverse Transcription Polymerase Chain Reaction (RTPCR). Results: There were 163 COVID-19 patients with diabetes consisting FPG 241.65±122.23 mg/dl, PPG 286.01±123.92 mg/dl, and HbA1c 9.49±2.41%. There is a significant correlation between NRL and hemoglobin, white blood cells, platelets, neutrophils, and D-dimers (all, p<0.001*). Conclusion: Diabetes is the commonest comorbidity in COVID-19 patients, and NLR and the others inflammatory assessment have reliable parameters for assessing and evaluating the prognosis of the COVID-19 patients as well as an accurate and practical coagulation parameter for predicting mortality.

Predicting the Risk of Mortality for Patients Diabetic with Coronavirus Disease (COVID-19): A Retrospective study Dharma Lindarto; Fransiscus Ginting
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.10319

Background. One of the biggest causes of mortality of patients diabetic with COVID-19 in the globe is diabetes mellitus. The study's goal was to examine the predicting the risk of mortality for patients diabetic with coronavirus disease (COVID-19). Methods. This is a retrospective study of patients diabetic with COVID-19 on 22 June 2020 to 21 July 2021 in H. Adam Malik Hospital Medan from 22 June 2020 to 21 July 2021. We collected all the data from electronic medical records on diabetics with SARS-CoV-2 infection, including demographic, clinical, laboratory, and radiological characteristics, treatments, complications, and clinical outcomes. All patients had throat swabs taken from their upper respiratory tracts to determine whether they had SARS-CoV-2 infection. Diagnosis of diabetes mellitus used ADA criteria. Results: There were 163 diabetic patients with COVID-19, consisting of mild (0%), moderate (39.8%), severe (44.2%), and critical (16.5%), and the most comorbid disease is hypertension. There was a significant age difference, length of stay, blood routine, and certain inflammatory markers between patients Diabetic with COVID-19 discharged from the hospital and died (all, p<0.05). The predicted death of patients diabetic with COVID-19 was D-dimer (OR: 4.069; p=0.008*;95% C.I: 1.43-11.55) and dexamethasone use (OR:4.769; p=0.007*; C.I: 1.54-14.71). Conclusion. The use of dexamethasone and the increase of D-dimer values increase mortality predictions in treating diabetic patients with COVID-19 in hospitals. To prevent these harms, the management of inpatients diabetic with COVID-19 must be with good glucose consideration and monitoring.

C-Reactive Protein (CRP) Levels in Stadium 5 Chronic Kidney Disease with Hemodialysis Regularly and Covid-19 Cut Safira Alifa; M. Feldi Gazaly Nasution
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.11928

Background: Chronic Kidney Disease (CKD) is kidney dysfunction that has occurred for more than 3 months. Patients with stage 5 CKD with hemodialysis (HD) regularly are prone to suffering from COVID-19 because hemodialysis patients can experience malnutrition, inflammation, and atherosclerosis. This study aims to determine CRP levels in stage 5 CKD with HD) regularly and COVID-19 at USU Hospital from June to October 2021. Method: One of the inflammatory biomarkers that can be used in assessing C-Reactive Protein (CRP) levels, by looking at these levels it is expected to know how severe the inflammation of the disease is. This is an observational descriptive study with a total sampling technique. Data were obtained secondarily from the medical records of stage 5 chronic kidney disease patients with COVID-19 with HD regularly. Result: Of the total 28 data, there were male 23 (82.1%) and female.5 (17.9%) patients. Most of them have aged 40-60 years old, and the clinical picture of patients was shortness of breath, with comorbid hypertension. In this study, the most HD duration was for 12-36 months and the highest level of CRP is > 200 mg/dl. Conclusion: The patients with CKD with HD regularly and covid-19 have increased inflammatory markers of CRP

Inflammatory Mediators as Predictors of Improved Functional Capacity after Phase 2 Cardiac Rehabilitation in Coronary Artery Bypass Surgery Patients Abdul Halim Raynaldo; Yuke Sarastri; Kamal Kharrazi Ilyas; Stefanie Tarigan
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.12145

Background: Inflammatory parameters correlate with the atherosclerotic acute coronary syndrome (ACS) process and can predict future cardiovascular events in healthy populations. Coronary heart disease (CHD) subjects who had undergone coronary artery bypass grafting (CABG) procedures and underwent cardiac rehabilitation must be prevented from increased cardiovascular events. The study aims to evaluate the effect of cardiac rehabilitation programs on marker inflammation of cardiovascular risk factors. Method: This study was conducted at Departement Cardiology and Vascular Diseases Integrated Heart Center H. Adam Malik Hospital Medan who had undergone CABG procedures and underwent phase I and II cardiac rehabilitation. All subjects were carried out to collect basic patient data based on anamnesis, physical examination, results of laboratory tests, and functional capacity of the heart. Result: The subjects of this study were male 26 (89.7%) subjects and female 3 (10.2%) subjects. The average BMI in this study was 26.4207±0.675 kg/m2, the most common CHD risk factor was smoking in 21 (72.4%) subjects, dyslipidemia in 20 (69%) subjects, hypertension in 18 (62.1%) subjects, obesity 14 (48.3%) subjects and T2DM 13 (44.8%) subjects. Based on echocardiography results, the average ejection fraction was 47.931±2.17 %, and 18 (62.1%) subjects had cardiomegaly. After undergoing phase I and II cardiac rehabilitation, there was improved significantly of the 6-minute walk test to hsCRP, IL-6, neutrophil-lymphocyte ratio (NLR), and functional capacity (all, p <0.001). IL-6 value is correlated significantly with functional capacity improvement (p<0.05) in both phase I and II cardiac rehabilitation. Conclusion: Cardiac rehabilitation (CR) should be considered as a preventive plan in the treatment of CHD patients. Physical exercise is noteworthy and they reduce morbidity and mortality due to reduced inflammation.

Correlation between Leptin and Free Testosterone Levels in Transfusion-Dependent Thalassemia Male Patients Dian Anindita Lubis; Karina Sugih Arto; Heny Syahrini
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.12159

Background: Male hypogonadism is a clinical disorder of low testosterone and spermatozoa due to impaired production that can occur at one or more levels in the hypothalamic-pituitary-gonadal (HPG) axis. Apart from iron accumulation, hypogonadism can also occur due to other mechanisms in thalassemia patients, such as the influence of adipose tissue and leptin. The study aimed to assess the relationship between leptin with free testosterone levels and BMI in transfusion-dependent thalassemia. Method: The research design chosen was analytic cross-sectional. The study was conducted at the adult thalassemia polyclinic of Cipto Mangunkusumo General Hospital and Fatmawati General Hospital, during the period July - December 2022. The samples used were male transfusion-dependent thalassemia patients aged over 18 years who were under control at the Thalassemia Polyclinic during the study period. The diagnosis of Thalassemia had been previously established by high-performance liquid chromatography (HPLC) or microcapillary examination. Result: Most patients were major ß thalassemia (87.8%), while HbE ß thalassemia was only 12.1%. Age distribution was with a median of 23 years (minimum-maximum 18-42 years). The clinical symptoms of hypogonadism were erectile dysfunction and decreased libido (12.1% and 9%, respectively). From body mass index examination were underweight 18 (54,5%), normal weight 13 (39,5%), overweight 1 (3%), and obese 1 (3%). Of the 33 transfusion-dependent thalassemia patients, 95% did not reach puberty according to their age (Tanner stage V). Conclusion: There is an association significantly between leptin levels with free testosterone and body mass index in transfusion-dependent thalassemia men.

Pharmacotherapy of Hypertension in Chronic Dialysis Patients in USU Hospital Medan Josep Henry Panjaitan; Feldi Gazaly
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.12193

Background: Hypertension is closely related to chronic kidney disease (CKD) patients because hypertension can be a cause or a result of hemodialysis (HD). The way that can be done to control blood pressure is the administration of antihypertensive drugs. The use of antihypertensive drugs in CKD on HD patients in hospitals is needed as an evaluation material in terms of the accuracy and optimization of drug administration. This study aims to know the administration pattern of antihypertensive drugs used by the HD unit in USU Hospital Medan. Method: Descriptive statistics were used to present the antihypertensive drug prescription pattern of CKD in HD patients. This study used data in the form of medical records and also direct interviews with patients and nurses of the HD Unit at USU Hospital in 2022. Results: The most common single drug antihypertensive used was Calcium Channel Blocker (CCB) as amlodipine 67.4% either alone or in combination. The most common 2 drugs antihypertensive combination were Angiotensin Receptor Blocker (ARB) as candesartan and CCB as amlodipine 19.5%. Conclusion: The most common single drug antihypertensive used was CCB, and the most common drugs antihypertensive in combination 2 drugs were CCB and ARB.

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Contact Name Dharma Lindarto

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Editorial Address Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

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Contact Name
Dharma Lindarto

Contact Email
jetromi@usu.ac.id

Phone
+6282168842564

Journal Mail Official
jetromi@usu.ac.id

Editorial Address
Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

Location
Unknown,

Unknown

INDONESIA