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Prodi Farmasi Fakultas Sains dan Teknologi Universitas Peradaban d/a Jl. Raya Pagojengan KM 3 Paguyangan, Kab. Brebes, Jawa Tengah, Indonesia 52276
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Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban
Published by Universitas Peradaban
ISSN : -     EISSN : 27766241     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Pharmacy Peradaban Journal (Pharm. PJ) merupakan jurnal ilmiah yang diterbitkan oleh Universitas Peradaban, dan dikelola oleh Departemen Farmasi, Fakultas Sains dan Teknologi. Ini adalah majalah profesional yang menawarkan akses terbuka untuk mempublikasikan penelitian yang relevan di semua bidang farmasi. Jurnal ini menyediakan wadah untuk artikel penelitian asli dan review dari berbagai topik kefarmasian. Jurnal ini menerbitkan manuskrip teoritis atau empiris dua kali dalam setahun yaitu pada bulan Januari dan bulan Juli. Jurnal menerapkan peer review untuk memastikan keaslian dan kualitas publikasi
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
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Search results for , issue "Vol 2 No 1 (2022): Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban" : 6 Documents clear
IDENTIFIKASI BAHAN TAMBAHAN PANGAN FORMALIN PADA BAKSO DAN TAHU YANG BEREDAR DI KECAMATAN SIRAMPOG M. Fikri Haikal; Baedi Mulyanto; Pudjono Pudjono
Jurnal Farmasi Universitas Peradaban Vol 2 No 1 (2022): Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban
Publisher : Prodi Farmasi Fakultas Sains dan Teknologi Universitas Peradaban

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Abstract

Peraturan Menteri Kesehatan Republik Indonesia Nomor 033 tahun 2012 tentang Bahan Tambahan Pangan mencantumkan bahwa formalin merupakan zat yang dilarang digunakan sebagai bahan tambahan pada pangan salah satunya bakso dan tahu. Penelitian bertujuan untuk mengidentifikasi dan mengetahui kadar bahan tambahan pangan formalin yang terkandung dalam bakso dan tahu yang beredar di Kecamatan Sirampog Kabupaten Brebes Provinsi Jawa Tengah. Penelitian menggunakan analisis kualitatif dengan pereaksi asam kromatrofat dan analisis kuantitatif dengan spektrofotometri UV-Vis. Analisis kualitatif dengan cara mencampurkan filtrat sampel dengan asam kromatrofat 0,5% dalam asam sulfat 60% lalu dipanaskan kemudian mengamati perubahan warna menjadi ungu (lembayung). Analisis kuantitatif dengan cara mengamati serapannya pada panjang gelombang maksimum 590,0 nm. Hasil penelitian kandungan bahan tambahan pangan formalin pada bakso dan tahu yang beredar di Kecamatan Sirampog Kabupaten Brebes Provinsi Jawa Tengah, dari 5 sampel bakso dan 5 sampel tahu yang diberi kode A, B, C, D, dan E menunjukkan 5 sampel bakso dan 3 sampel tahu mengandung bahan tambahan pangan formalin. Dari hasil pemeriksaan spektrofotometri UV-Vis kadar bahan tambahan pangan formalin yaitu untuk sampel bakso sampel A sebanyak 55,4 µg/gram, sampel B sebanyak 59,4 µg/gram, sampel C sebanyak 50,6 µg/gram, sampel D sebanyak 52,4 µg/gram, sampel E sebanyak 49 µg/gram dan sampel tahu sampel A sebanyak 50,4 µg/gram, sampel B sebanyak 55 µg/gram, sampel E sebanyak 58,2 µg/gram.
IDENTIFIKASI SILDENAFIL SITRAT PADA JAMU KUAT PRIA YANG BEREDAR DI WILAYAH BUMIAYU DENGAN METODE KROMATOGRAFI CAIR KINERJA TINGGI Nur Alimul Hakim; Tunjung Winarno; Pudjono Pudjono
Jurnal Farmasi Universitas Peradaban Vol 2 No 1 (2022): Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban
Publisher : Prodi Farmasi Fakultas Sains dan Teknologi Universitas Peradaban

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Abstract

Penelitian ini bertujuan untuk mengidentifikasi sildenafil sitrat pada sediaan jamu kuat pria yang beredar di Wilayah Bumiayu. Analisis kualitatif menggunakan KLT, pelarutnya adalah metanol, fase geraknya adalah metanol: kloroform (4: 1) dan fase diamnya adalah pelat Silica Gel GF254. Pengamatan noda dengan lampu UV 254nm. Hasil uji kualitatif pada 7 sampel positif sildenafil sitrat. Analisis kuantitatif menggunakan HPLC, fasa diam berupa kolom C18 (150mm x 3.9mm, 5µm) dan fasa gerak berupa buffer fosfat pH 3, metanol, rasio asetonitril (50:30:20). Sildenafil sitrat standar dengan konsentrasi 0,1mg/mL dalam fase gerak. Larutkan sampel uji yang diekstraksi dalam labu 100 mL menggunakan fase gerak. Pengujian menggunakan HPLC pada panjang gelombang 290nm dengan tekanan pompa 1 mL/menit dan volume injeksi 20µL. Hasil uji kuantitatif dari 7 sampel dengan kode A,B,C,D,E,F,G per kapsul adalah (103,53 mg), (90,23 mg), (33,44 mg), (45,63 mg) , (104,78 mg), ( 64,64 mg) dan (84,22 mg).
Persepsi pengunjung apotek terhadap keamanan dan efektifitas obat tradisional di Kecamatan Paguyangan tahun 2021 Efi Yulia Astuti; Aulia Rahman; Aziez Ismunandar
Jurnal Farmasi Universitas Peradaban Vol 2 No 1 (2022): Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban
Publisher : Prodi Farmasi Fakultas Sains dan Teknologi Universitas Peradaban

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Abstract

Traditional medicine is an ingredient or concoction of ingredients derived from plants, animal materials, mineral materials or a mixture of these materials that are used for generations by the community as treatment. The use of traditional medicine is not only influenced by characteristics, it can also be influenced by perceptions. The purpose of this study was to determine the perception of pharmacy visitors and to determine the relationship between characterictics and perceptions of the safety and effectiveness of traditional medicines in Paguyangan District. This type of research is an observational study using cross sectional method. Sampling using accidental sampling method, with a total of 100 respondents who meet the inclusion and exclusion criteria. Perception was measured using a questionnaire with a Likert scale from strongly disagree to strongly agree (scale 1-5). Then converted to percent index score. Spearman correlation test was used to determine the relationship between respondents characteristics and perceptions of the safety and effectiveness of traditional medicines. The results of the study obtained that respondents were gender (53%), age 18-40 years (63%), high school education level (39%), level of self employment (45%), and income less than Rp. 2.000.000 (61%). The majority of respondents agree with the perception of the safety of traditional medicine, while the perception of the effectiveness of traditional medicine is still uncertain. There is a significant relationship between the type of work of the respondents with the perception of the safety of traditional medicine with a significance value of 0.007 (p< 0,05), and there is relationship between the type of work with the perception of the effectiveness of traditional medicine with a significance value of 0.002 (p< 0,05). Keyword :Pharmacy Visitor, Perception, traditional medicine
Analisis Kandungan kalium Bromat dan Allura Red pada Saus Tomat dan Sambal di Pasar Tradisional Karangmoncol Febriyanto Bayu Aji; Eka Trisnawati; Tunjung Winarno
Jurnal Farmasi Universitas Peradaban Vol 2 No 1 (2022): Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban
Publisher : Prodi Farmasi Fakultas Sains dan Teknologi Universitas Peradaban

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Abstract

Food additives must pay attention to safety when using dyes or preservatives in food, which must be of good quality and have good nutritional value. Food and Drug Supervisory Agency received 57 news about food additive poisoning in food, namely 53 extraordinary events were found in Indonesia. The purpose of the study was to analyze the content of potassium bromate and allura red contained in tomato sauce and chili sauce at Karangmoncol Traditional Market, Purbalingga Regency, Central Java Province. The research method used is the color test method by reacting chemicals and the thin layer chromatography (TLC) method. The results showed that the potassium bromate in the sample which was reacted with 1% potassium iodide into 0.1 N hydrochloric acid obtained a negative result that no KBrO3 compound was found, while in allura red three samples A, B and C were found which were positive containing allura red, it is known from Fluorescence spotting standard Rf value of 0.64 which was compared with the sample Rf value of A (0.64), B (0.64) and C (0.64). Subsequent examinations used the UV-Vis spectrophotometric method to determine the allura red content in the sample, from the results of measurements and calculations that it was proven that three samples contained allura red compounds, namely sample A as much as 0.0583 mg, sample B as much as 0.0616 mg and sample C as much as 0. 0.0473 mg, with a maximum wavelength of 212 nm allura red while the results of linear regression y=0.007x-0.009 and the value of the correlation coefficient (r2) is 0.995. Keywords: Allura Red, Tomato Sauce and Sambal, TLC, UV-Vis Spectrophotometry.
AKTIVITAS ANTIBAKTERI EKSTRAK DAUN JAMBU BIJI (Psidium guajava,L.,) DENGAN PENYARI ETANOL DAN KLOROFORM TERHADAP PERTUMBUHAN Staphylococcus aureus Liana Fijriati; Luthfi Hidayat Maulana; Pudjono Pudjono
Jurnal Farmasi Universitas Peradaban Vol 2 No 1 (2022): Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban
Publisher : Prodi Farmasi Fakultas Sains dan Teknologi Universitas Peradaban

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Abstract

The high mortality rate in the world, especially in tropical areas such as Indonesia, is one of the causes of infectious diseases. Infectious disease is one of the problems in the health sector that many Indonesian people suffer from which from time to time continues to grow. This study aims to determine the antibacterial activity of guava leaf extract with 70% ethanol and chloroform extract against Staphylococcus aureus based on the diameter of the inhibition zone. The concentrations of the extracts used were 5%, 10%, and 15%. For the positive control, amoxicillin was used, and the negative control was 10% DMSO. Extraction was carried out by maceration by soaking 250 grams of guava leaf powder in 500 ml of 70% ethanol. The filtrate from the maceration was filtered, then the residue was macerated again with 500 ml of chloroform filter, then evaporated in a rotary evaporator. Produces a thick extract in ethanol as much as 10 grams, and in chloroform as much as 6 grams. The extract obtained was then tested for its antibacterial activity using Nutrient agar media by well diffusion. The results obtained showed the presence of antibacterial activity in each filter, namely 5%, 10% and 15% ethanol extract, respectively, of 4.6 mm; 8mm and 10 mm. Meanwhile, in 5% , 10% and 15% chloroform, respectively, they were 4.3 mm; 7.6 mm and 10.3 mm. Positive control of 20 mm amoxicillin and negative control with 10% DMSO solvent did not show any antibacterial activity. From the results of the study, it was also found that the concentration of 15% in both extracts had the highest antibacterial activity in inhibiting the growth of Staphylococcus aureus. Keywords: Guava leaves, Staphylococcus aureus, antibacterial, inhibition, well diffusion.
Formulasi Dan Evaluasi Mutu Fisik Sediaan Body Scrub Cream Varietas Ubi Jalar Orange Dan Ubi Jalar Putih Dalam Fase Air Dan Minyak Syaekhoni Laelatul Latifah; Pudjono Pudjono; Resa Frafela Rosmi
Jurnal Farmasi Universitas Peradaban Vol 2 No 1 (2022): Pharmacy Peradaban Journal (Pharm. PJ): Jurnal Farmasi Universitas Peradaban
Publisher : Prodi Farmasi Fakultas Sains dan Teknologi Universitas Peradaban

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Abstract

Free radicals are one of the causes of premature aging due to oxidative stress in the body, such as rough, dull, and dry skin. This triggers the need for skin protection against free radicals. One of the natural ingredients that can be used is sweet potato (Ipomoea batatas L.). The purpose of this study was to determine the antioxidant activity of body scrub cream preparations of orange sweet potato and white sweet potato varieties and to determine variations in body scrub cream formulations that were effective as antioxidants. Detection of beta-carotene content by TLC using petroleum ether/benzene (9:1) eluent showed results that were in accordance with the comparison standard of beta-carotene in both orange and white sweet potatoes showing yellow spots with an Rf value of 0.8. The body scrub cream in this study was made with formulas F1, F2, and F3 for orange sweet potatoes and formulas F4, F5, and F6 for white sweet potatoes. The results showed that the F3 formula had greater spreadability, while the F3 and F6 formulas provided a longer adhesion time, and did not irritate the skin. The antioxidant activity test using the DPPH (1,1-diphenyl-2-Picrylhydrazil) method showed that the body scrub cream with the formula F1, F2, F3, F4, F5, and F6 had antioxidant activity with an IC50 value of 30,38 μL/mL; 19,37 μL/mL; 11,18 μL/mL; 73,91 μL/mL; 40,04 μL/mL; and 33,19 μL/mL. The orange sweet potato variety with a concentration of 50% and an IC50 value of 11,18 μL/mL was the best antioxidant.

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