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Indonesian Journal of Life Sciences

IJLS
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Published by Indonesia International Institute for Life Sciences

ISSN : - EISSN : 26560682 DOI : http://doi.org/10.54250/ijls

Core Subject : Health, Science, Agriculture, Engineering,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Medicine & Pharmacology

The Indonesian Journal of Life Sciences (IJLS) is a journal published by Indonesia International Institute for Life Sciences Press (i3L Press). IJLS is a scientific journal contains original research articles, review articles, and short communication covering all aspects in life sciences. This journal provides immediate open access to its content on the principle that making research freely available to the public to support a greater global exchange of knowledge. Readers can view abstracts and download full-text articles (PDF) free at any cost. All manuscripts submitted to the Indonesian Journal of Life Sciences will be screened for plagiarism and blind peer-reviewed to present valuable and authentic findings in life sciences. Authors with original, clearly analyzed, and logically interpreted research result in the scope of food innovation and nutrition, bio-products and services for sustainable society, information technology in life sciences, as well as health and well-being are very welcome to submit their articles. Every article issued to the editorial of the Indonesian Journal of Life Sciences is free of charge including the cost of repairing the article. IJLS is published bianually on March and September. Manuscripts are accepted on a continuous basis and the submisison is opened through the year.

Arjuna Subject : Imunologi dan Mikrobiologi (semua kategori) - Mikrobiologi dan Bioteknologi Terapan

Articles 55 Documents

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Inulin from Several Tubers Available in Indonesia and the Growth of Gut Microbiota Ivan Crespo; Augusto Arindra; Jessica Tashia Lualdi; Phoebe Anadita Rimba; Agus Budiawan Naro Putra; Ritchie Rahardja
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

Indonesia has many types of tubers, some of them are gembolo tuber (Dioscorea bulbifera), lesser yam (Dioscorea esculenta), yam bean (Pachyrhizus erosus), and dahlia tuber (Dahlia pinnata); which are the sources of prebiotics. The term of prebiotics has been used since 1995 to describe the non-digestible components in food that positively alter gut microbiota activity and exhibit beneficial properties to the human body. One of the prebiotics that can be found in tubers is inulin. This review was aimed to compare inulin content in the above-mentioned tubers and their roles towards the growth of gut microbiota. Library searches using Semantic Scholar database was done. Findings showed that gembolo tuber contains the highest inulin content, followed by lesser yam, dahlia tuber, and yam bean. Moreover, inulin increases the population of Lactobacillus, Bifidobacterium, and Bacteroides while inhibits the growth of Escherichia coli and reduce the growth of Clostridium.

Meta-Analysis: Effectiveness of SSRIs vs SSRIs in conjunction with CBT in treating depression in young adolescents Gabriele Mustika Kresnia; Winda Hasuki; Nanda Rizqia Pradana ratnasari
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

Objective: To compare the efficacy of SSRI medication alone and SSRI+CBT combined. Methods: NCBI Pubmed, DARE, CSDR and NGC were searched October-November 2019. The population size, as well as the base and endpoint CGAS mean and standard deviation from the three studies included, are recorded. Statistical analysis was done in RStudio with the "meta" package. Results: For the SSRI only, the effect size was -1.82 with a 95% confidence interval between -2.28 and -1.37. For the SSRI and CBT combined, the effect size was -1.68 with a 95% confidence interval between -2.39 and -0.98. The effect size for both SSRI and SSRI + CBT didn't cross the null effect line, but the heterogeneity exceeds 50%. The result for the comparison of post SSRI vs. SSRI + CBT showed the effect size of -0.05 with a 95% confidence interval between -0.23 and 0.12. The size effect did cross the null effect line, but the heterogeneity was less than 50%. Conclusion: Both methods were shown to be effective. However, due to statistical inconsistencies, it couldn’t be concluded whether the combination of SSRI and CBT is better than treatment with SSRI alone.

What do T cells see in SARS-CoV2? Marsia Gustiananda
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

The current epidemic caused by a novel coronavirus SARS-CoV2 as well as two previously documented pandemic caused by SARS-CoV and MERS-CoV imposes that a spillover of an animal coronavirus to humans is a continuous threat. The zoonotic nature of the infection contributes to the unpredictability of the pandemic. In such situations, the availability of the ‘off the shelf’ vaccines that target the conserved region of the coronavirus might help in preventing the spread of the diseases. Therefore, efforts to generate such vaccines should be considered as a priority. The whole genome of SARS-CoV2 is readily available in the public database one month after the first case was identified. The platform technology known as the “genome to vaccine” approach would provide useful start to identify parts of the virus proteome which can be the candidate for vaccine components. This study used an immunoinformatic approach to identify T cell epitopes from SARS-CoV2 ORF1ab polyprotein in an attempt to design a genome-derived epitope-based universal coronavirus vaccine.

A Review of Phytochemical Properties and Therapeutic Activities of Glebionis coronaria Evelyn Jeanette Wijaya; Joshua Nathanael; Orlando Carolan; Shakila Angjaya Adiyanto; Wiranata Buntaran Bun; Agnes Anania Triavika Sahamastuti
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Glebionis coronaria, formerly Chrysanthemum coronarium, is one of the medicinal herbs that belong to the Asteraceae family. This review paper aims to provide information regarding the botanical description, distribution, and phytochemical properties which contribute to the medicinal properties of Glebionis coronaria. Various studies have reported the presence of tannins, vitamins, macro- and microelements, beta-carotene, carbohydrates, protein, and other bioactive compounds in the plant’s essential oil, extract, or plant parts. Researchers have uncovered the potential pharmaceutical activities of the plant, including antibacterial, antifungal, antioxidant, anti-inflammatory, anti-cholesterol, to the potential anticancer properties. Based on the scientific evidence collected, G. coronaria has the potential to be used in many clinical areas for medicinal purposes. However, appropriate clinical testing should be pursued to evaluate the medicinal effects of this plant.

Phytochemical Screening, Therapeutic Benefits, and Adverse Effects of Citrus aurantifolia - A Review Erika Chriscensia; Elizabeth Chrestella Wibowo; Gregorius Enriko; Owen Chrisfian Wijaya; Agnes Anania Triavika Sahamastuti
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Key lime or Citrus aurantifolia has been well known for its functions, either as food or medicine. This fruit has a greenish-yellow color with a sour and bitter taste and distributed initially from East Asia. This review summarizes the phytochemical screening, therapeutic effects, and adverse effects of key lime. Most parts of the plant contain phytochemicals, such as phenols, flavonoids, steroids, terpenoids, and alkaloids, with other varying compounds like saponin, tannin, anthraquinone, glycosides, and carbohydrates that may be due to the country where the plant is grown, or the extraction methods. Some studies have been conducted to evaluate the therapeutic effects of key lime, including antibacterial, antioxidant, anticancer or antitumor, anti-cholesterol, anti-larvae, anti-mosquito, antidiabetic, anti-inflammatory, and anticholinesterase. Key lime also may cause some adverse effects, such as phytophotodermatitis. It may lead to toxicity manifested in conditions such as edema, inflammation, or necrosis in some organs in the body, an increase in lymphocytes & liver enzymes, and a decrease in hemoglobin.

A Review of Botany, Phytochemical, and Pharmacological Effects of Dysphania ambrosioides Lavisiony Gracius Hewis; Giovanni Batista Christian Daeli; Kenjiro Tanoto; Carlos Carlos; Agnes Anania Triavika Sahamastuti
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Traditional medicine is widely used worldwide due to its benefits and healthier components that these natural herbs provide. Natural products are substances produced or retrieved from living organisms found in nature and often can exert biological or pharmacological activity, thus making them a potential alternative for synthetic drugs. Natural products, especially plant-derived products, have been known to possess many beneficial effects and are widely used for the treatment of various diseases and conditions. Dysphania ambrosioides is classified as an annual or short-lived perennial herb commonly found in Central and South America with a strong aroma and a hairy characteristic. Major components in this herb are ascaridole, p-cymene, α-terpinene, terpinolene, carvacrol, and trans-isoascaridole. Active compounds isolated from this herb are found to exert various pharmacological effects including schistosomicidal, nematicidal, antimalarial, antileishmanial, cytotoxic, antibacterial, antiviral, antifungal, antioxidant, anticancer, and antibiotic modulatory activity. This review summarizes the phytochemical compounds found in the Dysphania ambrosioides, together with their pharmacological and toxicological effects.

ARI(1,1) Model for Predicting Covid19 in Indonesia Nanda Rizqia Pradana ratnasari
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Covid19 modelling is needed to help people understanding the distribution or pattern of the data and doing the prediction. The data used for modelling in this study was ‘confirmed cases’ of Covid19 in Indonesia recorded from March 2 to August 23, 2020. Model obtained from analysis was ARI(1,1) with estimated parameter 0.9859 and standard error 0.0114. Maximum Likelihood was the method conducted to estimate the parameters. The model was good to predict the actual data of Covid19 confirmed cases in Indonesia. Keywords: Covid19, autoregressive, prediction.

A Review on the Antimicrobial Properties of Giant Barrel Sponge- Xestospongia sp. Leonny Hartiadi; gisella edny; Jeannifer Rebecca; Sheryl Sheryl; Audrey Amira Crystalia
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

Indonesia sits in the heart of the largest biodiversity hotspot -Indo-Pacific region. Indonesia has access to endless resources of bioactive compounds from marine animals and plants. Marine sponges have been extensively studied over the years due to their nature of being exposed to various microorganisms. Xestospongia sp. establishes a symbiotic relationship with diverse microorganisms, leading to the synthesis of abundant bioactive resources which capable of inhibiting the growth of pathogenic bacteria. Publications from the last ten years were retrieved from PubMed and included in this review article. Bioactive compounds produced by Xestospongia sp. were effective in inhibiting gram-negative bacteria- P. aeruginosa, A. baumanii, E. coli, K. pneumoniae, P. aeruginosa, S. epidermis, S. typhi- and gram-positive bacteria -M. Intracellulare, S. aureus, S. pneumoniae, B. subtilis, V. anguaillarum. In addition, extracts were able to inhibit the growth of multidrug-resistance P. aeruginosa and methicillin-resistant S. aureus (MRSA). C. albicans, C. tropicalis, C. neofarmans, A. niger, Epidermophyton sp., M. gypseum, T. rubrum, T. mentagrophytes were susceptible to Xestospongia sp. extracts. The growth of chloroquine-resistant and susceptible strains of P. falciparum were inhibited by Xestospongia sp. with similar zones of inhibitions. The antimicrobial properties were contributed by the composition of chemically complex compounds such as phenolics, steroids and alkaloids; each of which exhibits a unique mechanism of action. The vast range of antimicrobial activity exhibited by Xestospongia sp. extracts implies their promising role in clinical settings for the treatment of infectious diseases including tuberculosis and malaria.

Development of Healthier Cookie Product by Utilizing Different Formulations of Durian Seed Flour Rayyane Mazaya Syifa Insani; Adrian Dhama
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .02
Publisher : Indonesia International Institute for Life Sciences

The increasing fast food production led to decreased consumption of dietary fiber food and increased risk of obesity and cardiovascular disease. Hence, this study aimed to utilize durian seed flour in making a healthy cookie product and observe the effect of different durian seed flour formulation (0%, 25%, 50%) to the organoleptic properties of the cookies. The cookies were analysed through sensory analysis and further statistical analysis. The addition of different formulations of durian seed flour did not significantly affect the aroma, taste, aftertaste, and overall liking of the cookies, however, it did significantly affect the texture of the cookies. The formulated cookies made with the addition of durian seed flour had better overall organoleptic attributes especially in the texture attribute. Nevertheless, it is recommended to conduct chemical and rheological analysis for further characterization of the durian seed flour and its effect in the cookies for further studies.

Comparative Study Between Mixed Culture of Schizosaccharomyces Pombe with Saccharomyces and Single Culture Saccharomyces on Wine End Product Roselyn Mulyono; Veren Tania; Robert Heryson; Kenny Roy Felix; Nanda Risqia Ratnasari
Indonesian Journal of Life Sciences 2022: IJLS Vol 04 No .01
Publisher : Indonesia International Institute for Life Sciences

Wine industry has always been searching for a way to improve the quality of its produce. Lately, the trends of using mixed culture of yeast to improve the wine qualities in the wine industry are increasing. The aim of this systematic review is to determine whether or not the mixed culture of Schizosaccharomyces pombe and Saccharomyces cerevisiae actually improves the quality of the wine. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to conduct the systematic review, and studies performed from 2010-2020 were collected from the databases of MDPI, ScienceDirect, Semantic Scholar, and PubMed. A total of 54 studies are systematically reviewed in this paper. Pure fermentation of S.cerevisiae produced generally acceptable wine qualities with desirable amounts of ethanol and acceptable amount of secondary metabolites, however in recent findings S.cerevisiae cannot naturally degrade malic acid, leading to a too sour-taste wine. Meanwhile, pure fermentation of S.pombe results in the high production of polysaccharide, pyranoanthocyanin, glycerol, pyruvic acid, urease; reduction of malic acid and gluconic acid, altogether considered as desirable traits in wine production. Mixed fermentation with S.cerevisiae and proper strain selection of S.pombe are the solutions for the suppressed production of acetic acid, acetaldehyde, and acetoin, which are the undesirable compounds highly produced by Schizosaccharomyces. The hypothesis is proven to be true as mixed fermentation of S.cerevisiae and S.pombe results in enhanced wine quality, especially contributed by the compounds produced from S.pombe fermentation.

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Slamet Supriadi

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Indonesian Journal of Life Sciences LPPM - Indonesia International Institute for Life Sciences (i3L) Jl. Pulomas Barat Kav. 88, Jakarta Timur, 13210 Indonesia

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Dki jakarta

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Slamet Supriadi

Contact Email slamet.supriadi@i3l.ac.id

Phone +622129567888

Journal Mail Official ijls@i3l.ac.id

Editorial Address Indonesian Journal of Life Sciences LPPM - Indonesia International Institute for Life Sciences (i3L) Jl. Pulomas Barat Kav. 88, Jakarta Timur, 13210 Indonesia

Location Kota adm. jakarta timur, Dki jakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Slamet Supriadi

Contact Email
slamet.supriadi@i3l.ac.id

Phone
+622129567888

Journal Mail Official
ijls@i3l.ac.id

Editorial Address
Indonesian Journal of Life Sciences LPPM - Indonesia International Institute for Life Sciences (i3L) Jl. Pulomas Barat Kav. 88, Jakarta Timur, 13210 Indonesia

Location
Kota adm. jakarta timur,

Dki jakarta

INDONESIA