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Bayu Brahma
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INDONESIA
Indonesian Journal of Cancer
Published by National Cancer Center-Dharmais Cancer Hospital
ISSN : 19783744     EISSN : 23556811     DOI : https://www.doi.org/ 10.33371
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
Indonesian Journal of Cancer is a peer-reviewed and open-access journal. This journal is published quarterly (in March, June, September, and December) by Dharmais Cancer Hospital - National Cancer Center. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical cancer research. Articles are original research that needs to be disseminated and written in English. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted acceptance for publication. The journal publishes original research articles, case reports, and review articles under the following categories: cancer management, cancer prevention, cancer etiology, epidemiology, molecular oncology, cancer diagnosis and therapy, tumor pathology, surgical oncology, medical oncology, radiation oncology, interventional radiology, as well as early detection.
Arjuna Subject : Kedokteran - Onkologi
Articles 3 Documents
 1 
Search results for , issue "Vol 8, No 2 (2014): April-Juni 2014" : 3 Documents clear
Gambaran Computed Tomografi Scan Toraks Teratoma Kistik Paru DETI NURBAETI; AZIZA G ICKSAN; HERIAWATY HIDAYAT
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v8i2.304

Abstract

Pulmonary cystic teratoma is a very rare disease, composed of tissues from more than one germ cell line. Pulmonary cystic teratoma commonly involve the upper lobe of the left lung, most follow a benign course and are incidental findings during routine chest X-rays. Proper diagnosis is needed to determine adequate treatment in order to reduce symptoms and improve quality of life. We report a twenty six years old man with clinical symptom hemoptysis, chest pain and dyspnea since one month before admission. The chest X-ray showed a large opacity of the entire right hemithorax, there is no calcification. On enhanced chest CT examination, we found an encapsulated cystic mass on the upper and middle of the right lung with peripheral enhancement. Histopathological examination confirmed an infected cyst with cystic teratoma. The main purpose of this report is to emphasize the importance of enhanced chest CT in evaluating patient suspected pulmonary cystic teratoma.
Akurasi Kadar Lysophosphatidic Acid Plasma dan Ca125 Serum Penderita Tumor Ovarium Jenis Epitel untuk Prediktor Keganasan Ovarium TRI APRILIAWAN; BRAHMANA ASKANDAR
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v8i2.300

Abstract

This study was conducted to determine and compare the sensitivity, specificity, positive predictive value and negative predictive value between CA125, Lysophosphatidic Acid Plasma (LPA) and combination of LPA - CA125 in patients with ovarian mass.This study was a analytic observational cross sectional studies, with 56 subjects who had ovarian tumors, who had the inclusion and exclusion criteria research, in Department of Obstetrics and Gynecology FK-Unair/dr. Soetomo Hospital, Surabaya. After that, patients performed surgery, and histopatology examination of operation specimens in this hospital. Inclusion criteria for this study were patients with epithelial ovarian tumors from Anatomical Pathology examination. The 56 study subjects , we were divided into 2 groups based on histopatological examination, one group with 31 subjects we classified into epithelial type malignant ovarian tumors study group, while the other group consist of 25 subjects we classified into epithelial type benign ovarian tumors study group.Sensitivity, specificity, positive predictive value, negative predictive value of CA125 was 87.1%; 28%; 60%; and 63.8%. Sensitivity, specificity, positive predictive value, negative predictive value LPA was 51.6%; 76%; 72.7%; and 55,9%. And sensitivity, specificity, positive predictive value, negative predictive value combination LPA - CA125 was 45.2%; 92%; 87.5%; and 57.5%. And in this study we get the CA125 cut-off at 50 u/mL gives better results than 35 u/mL, whereas the LPA cut-off 2.5 ?M still the best, although the Kappa analysis results for both are not significant.In this study, plasma LPA level patients with ovarian tumor can not be used as a tumor marker for epithelial malignant ovarian cancer. CA125 levels can be used as a tumor marker for epithelial malignant ovarian cancer, while combination of CA125 levels and LPA levels increase the specificity but does not increase the sensitivity. This was contrast with previous studies that the sensitivity and specificity of plasma LPA is excellent and they proposed use LPA plasma as a tumor marker.
Sistem Skoring Nefrometri R.E.N.A.L: Sistem Berstandar yang Komprehensif Dalam Menilai Ukuran, Lokasi, dan Kedalaman Tumor Ginjal MOCHAMMAD REZA; ARIEF RAKHMAN; CHAIDIR A MOCHTAR
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v8i2.301

Abstract

The treatment of localized renal cell carcinoma remains subjective.The R.E.N.A.L.- Nephrometry Score quantifies the characteristics of renal mass anatomy based on radiologic findings to provide a standardized objective descriptive system in an reproducible manner. We evaluate the utility of this system in predicting tumor resectability, operative approach and risk of complication, and their relevance to clinical practice.Electronic literature research was performed to access the main series of literature in the past 4 years since the scoring system developed. The articles were then analyzed and selected to address these issues. Fifteen peer-reviewed publications (2009 to 2012) were selected. Most of the studies were analyzed using the prospective acquired database. Increasing tumor complexity was asscociated with greater overall nephrometry score in patient underwent renal neprectomy and partial neprectomy. Compared with patients who underwent partial nephrectomy, the patients treated with radical nephrectomy had a significantly greater size (R), central proximity (N), and location (L) component scores. There were more complications among patients with higher R.E.N.A.L scores who underwent partial nechrectomy (PN) thanin patients with PN who did not developcomplications. The R.E.N.A.L nephrometry scoring system has good interobserver reliability showed by the similar sum of nephrometry score concordance to the R, E, N, A, and L components among surgeons in different centre. The R.E.N.A.L nephrometry standardize the reporting of solid renal masses and appears to effectively stratify the treatment choice for patients. Nephrometry aids in objectifying previously subjective measure and provide more meaningful comparison of treatment recommendation or results in published series.

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