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INDONESIA
Herbal Medicine Journal
Published by Sekolah Tinggi Ilmu Kesehatan Senior Medan
ISSN : -     EISSN : 26212625     DOI : https://doi.org/10.58996
Core Subject : Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology
Herbal Medicine Journal menerima artikel penelitian dalam 2 area utama di bidang farmasi: Sains Farmasi dan Farmasi Komunitas dan Klinis. Dalam bidang sains farmasi, artikel penelitian yang diterima meliputi Biologi Farmasi dan Farmakognosi, Kimia Farmasi, Farmasetika, Farmakologi dan Toksikologi, dan juga Bioteknologi. Sedangkan area Farmasi Komunitas dan Klinis mencakup Farmasi Rumah Sakit, Farmasi Klinis, Manajemen Farmasi, dan Farmasi Sosial.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 6 Documents
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Search results for , issue "Vol 5 No 2 (2022): Herbal Medicine Journal" : 6 Documents clear
Hubungan Pengetahuan Terhadap Sikap Remaja Desa Ujung Tanduk Kecamatan Laguboti Kabupaten Toba Tentang Swamedikasi Jerawat Tahun 2021 Baharuddin J.E.A. Togatorop; Devi Yanthre Sari Manurung; Melva Epy Mardiana Manurung; Riris Sianipar
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.994 KB) | DOI: 10.58996/hmj.v5i2.49

Abstract

Acne is one of the physical problems experienced during adolescence. The prevalence of acne sufferers in Indonesia ranges from 80-85% in adolescents with a peak incidence of 15-18 years of age. Acne often causes a lack of self-confidence of a teenager. A teenager with acne will try to treat it and treatment in general will be done with self-medication. A person's knowledge and attitude will affect the individual's way of behaving, including in carrying out treatment by means of self-medication. This research was conducted on teenagers in Ujung Tanduk Village, Laguboti District, Toba Regency where there were 60 populations and samples were taken as many as 45 respondents, which were collected in WhatsApp groups. Based on the research that has been carried out, 64.4% of respondents have good knowledge and the remaining 35.6% are knowledgeable enough and there are 48.9% of respondents who have good attitudes, 33.3% are moderate and 17.8% have poor attitudes, and found a relationship between knowledge and good attitudes. evidenced by the results of statistical tests (Chi Square test) where the p value <0.05.
Formulasi Sediaan Gel dari Ekstrak Metanol Biji Alpukat (Persea americana Mill.) Sebagai Penyembuh Luka Sayat Pada Tikus Jantan (Rattus norvegicus) Vera Estefania Kaban; Nasri Nasri; Hariyadi Dharmawan Syahputra; Raissa Fitri; Zulmai Rani; Muhammad Fauzan Lubis
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (373.901 KB) | DOI: 10.58996/hmj.v5i2.50

Abstract

The avocado (Persea americana Mill.) is a fruit that is often found. This versatile fruit has many benefits for humans. The benefits of avocado are as anti-hyperlipidemic, analgesic, anti-inflammatory, anticonvulsant, hypoglycemic, hypercholesterolemic, wound healing and prevent cancer. The aims of this study was to make avocado seed methanol extract into a gel preparation and to determine the effect of avocado seed methanol extract gel and at what concentration the effective treatment for wounds in mice and its comparison with Star Ag gel as a positive control. The research was conducted using an experimental method. The manufacture of avocado seed methanol exstract was carried out by maceration method using methanol as a solvent. The result of the study were statistically analyzed using One Way Anova. The result of the data analysis at a concentration of 5% obtained a sig value <0,05. Based on One Way Anova analysis of the five treatments, the most effective was avocado seed methanol extract gel with a concentration of 5%.
Pengujian Efek Hipoglikemik Fraksi Petroleum Eter dan Etil Asetat Daun Dandang Gendis (Clinacanthus nutans (Burm. F.) Lindau) Junius Gian Ginting
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (420.611 KB) | DOI: 10.58996/hmj.v5i2.51

Abstract

The investigation had been done about hypoglycaemic effect from Clinachanthus nutans (Burm f.) Lindau extract, which in petroleum ether extract and ethyl acetate extract, that used Glucose Method Tolerance for Mice. The extract of Clinachanthus nutans (Burm f.) Lindau leave was carried out by masseration and using ethanol 80% as solvent, and gradually fractination for ethanol extract with petroleum ether and ethyl acetate solvent. Further, the glucose tolerance had been done for petroleum ether fraction and ethyl acetate. The mice was fasting during 17 hours and the blood glucose level and weight of mice was measured and given the 50% glucose liquid with dose 4 mg/kg bw. After 30 minutes the blood glucose level can be measure again. Divided the mice to 6 group, Group I: control (CMC 0,5% dose 1 % bw); Group II until Group V given the petroleum ether fraction and ethyl acetate fraction with dose 15, 30, 45 dan 60 mg/kg bw; Group VI: given the Glibenclamid suspension dose 1 mg/kg bw as equal. Fixed blood glucose level of mice after 60, 90, 120, 150 and 180 minutes to have use of glucometer (EZ Smart). The result showed that petroleum ether extract doesn’t have hypoglycaemic effect, but in dose 45 and 60 mg/kg bw has given hypoglycaemic effect which to get near Glibenclamid suspension in dose 1 mg/ kg bw with blood glucose level decrease 0,05 (ɑ=0,05).
Diameter Zona Hambat Antibiotik Amoxicillin dan Tetracycline terhadap Escherichia coli Helen Anjelina Simanjuntak; Herlina Simanjuntak; Siti Maimunah; Rahmiati Rahmiati; Toberni S Situmorang
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (355.685 KB) | DOI: 10.58996/hmj.v5i2.52

Abstract

Antibiotics are drugs used for infections caused by bacteria. Amoxicillin and tertacycline are antibiotics used to inhibit the growth of Escherichia coli. Escherichia coli bacteria can cause urinary tract infections, diarrhea, gastroenteritis, pneumonia, septicemia, and meningitis. The purpose of this study was to determine the diameter of the inhibition zone of amoxicillin and tetracycline antibiotics in inhibiting Escherichia coli bacteria. Experimental research method with antibacterial activity test using paper disc diffusion method. The results showed that amoxicillin and tetracycline antibiotics had inhibition zone diameters of 18.4 mm and 35.76 mm, respectively, with strong and very strong categories. The conclusion of this study is that tetracycline antibiotics are better at inhibiting the growth of Escherichia coli bacteria than amoxicillin.
Penetapan Kadar Metronidazole dalam Sediaan Tablet Secara Spektrofotometri Infra Merah Jimmi J
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (475.402 KB) | DOI: 10.58996/hmj.v5i2.70

Abstract

Metronidazole is a type of antibiotic that has been widely used since 1960, and has been shown to be active against various anaerobic bacteria in vitro and experimental infections. According to Law Number 36 of 2009 concerning Health in paragraph 1 of article 105, it is stated that pharmaceutical preparations in the form of drugs and medicinal raw materials must meet the requirements of the Indonesian Pharmacopoeia or other standard books. The purpose of this study was to determine the concentration of metronidazole in tablets with trade names and generics and to determine the conformity of the levels to the requirements of the Indonesian Pharmacopoeia. Determination of paracetamol levels by Fourier Transform Infra Red (FTIR) Spectrophotometry using methanol solvent in the range of wave numbers 400 – 4000 cm-1. The results showed that the concentration of metronidazole in Novagyl® tablets (97.45 ± 0.36)%; Trichodazole® tablets (97.41 0.36)%; Metronidazole® tablets (94.42 0.40)%; Omenizole® tablets (99.07 0.13)%; Farizol® tablets (92.12 1.39)%. From the validation of the method carried out, the results of the recovery test were 100.9%, RSD 0.07%, and had LOD and LOQ of 3.3351 mg/mL and 11.1110 mg/mL respectively. These results indicate that the method used shows accurate and thorough results. The results of the study concluded that the determination of metronidazole levels could be carried out using Fourier Transform Infra Red (FTIR) spectrophotometry and the levels of metronidazole tablets met the requirements.
Formulasi dan Uji Stabilitas Fisik Sediaan Lulur Krim Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Zuhairiah Nasution; Mutiara Agustina Nst; Puput Fransiska Hareva
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (402.64 KB) | DOI: 10.58996/hmj.v5i2.71

Abstract

Scrub cream is a pharmaceutical preparation which function is to remove dead skin cells, moisturize and brighten the skin with the help of scrub ingredients. One of the natural ingredients used as raw material for scrub cream is fragrant pandan (Pandanus amaryllifolius Roxb.). The aim of this study was to make a cream scrub preparation from pandan extract with various concentrations of 3%, 3.5% and 4%. This research was conducted experimentally. Preparation testing includes organoleptic test, homogeneity test, pH test, irritation test, spreadability test, stability test, and emulsion type test. The results of the physical quality inspection of the scrub cream from pandan Wangi extract showed that the preparation was homogeneous, had an M/A emulsion type, had a pH value of 6.1-6.5, did not cause irritation and did not change during storage for 4 weeks except for the preparation with a concentration of 3.5% because the preparation underwent a change in the breakdown of the emulsion in the preparation on storage starting from the 3rd week. From the research that has been done, it can be concluded that Pandanus amaryllifolius Roxb extract can be formulated as a scrub cream with a variation of concentration of 3%; 3.5% and 4% and does not irritate the volunteers' skin.

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