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Eruditio : Indonesia Journal of Food and Drug Safety

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Published by Badan Pengawas Obat dan Makanan

ISSN : 27472493 EISSN : 28076222 DOI : https://doi.org/10.54384

Core Subject : Health, Science, Agriculture,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology Public Health

Eruditio : Indonesia Journal of Food and Drug Safety adalah jurnal yang diterbitkan oleh Pusat Pengembangan Sumber Daya Manusia Pengawasan Obat dan Makanan (PPSDM POM), Indonesia. Jurnal ini memuat hasil kajian dan kajian literatur di bidang keamanan Obat dan Makanan.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 6 Documents

Search results for , issue "Vol 1 No 1 (2020): Edisi Desember" : 6 Documents clear

Validasi Metode Analisis Identifikasi Simultan Hidrokuinon dan Asam Retinoat Secara UHPLC-PDA dalam Produk Kosmetika Mohammad Ibnu Fajri
Eruditio : Indonesia Journal of Food and Drug Safety Vol 1 No 1 (2020): Edisi Desember
Publisher : Badan Pengawas Obat dan Makanan

Penggunaan Hidrokuinon dan Asam Retinoat pada produk kosmetik tanpa resep dokter tidak diizinkan menurut peraturan yang berlaku di Indonesia. Metode analisis yang tersedia saat ini masih menggunakan sistem HPLC yang dijalankan secara individual untuk masing-masing senyawa dan membutuhkan waktu analisis yang lama. Oleh karena itu, diperlukan pengembangan metode yang lebih cepat dan efisien. Pengembangan metode analisis identifikasi simultan Hidrokuinon dan Asam Retinoat dijalankan menggunakan Ultra High Performance Liquid Chromatography (UHPLC) dengan detektor PDA, kolom Hypersil GOLD® C18 (150 mm x 2.1 mm 3µm), fasa gerak metanol - asam format 0,1% dengan sistem gradien, laju alir 0,35 mL/menit dan dideteksi pada 290 nm untuk hidrokuinon dan 354 nm untuk asam retinoat. Parameter validasi yang dilakukan adalah selektivitas dan batas deteksi. Hasil validasi metode menunjukkan waktu retensi untuk hidrokuinon pada 1,93 menit dan untuk asam retinoat pada 11,99 menit. Tidak ada peak yang memberikan waktu retensi yang sama baik pada pelarut maupun larutan sampel. Persamaan kurva kalibrasi untuk hidrokuinon adalah y = 11591x + 1312 (r = 0.999) dan untuk asam retinoat adalah y = 37839x + 17732 (r = 0.999). Nilai batas deteksi dari hidrokuinon dan asam retinoat sebesar 5,92 µg/g dan 7,74 µg/g secara berurutan. Metode ini valid digunakan untuk analisis hidrokuinon dan asam retinoat pada sampel produk kosmetika, serta 67% cepat dan 90% lebih hemat fasa gerak dibandingkan metode yang tersedia saat ini.

Peningkatan Pemahaman Penyidik BPOM dan Strategi dalam Pengawasan Post Border: RIA Framework Tofa Apriansyah; Khusnul Khotimah; Adis Imam Munandar
Eruditio : Indonesia Journal of Food and Drug Safety Vol 1 No 1 (2020): Edisi Desember
Publisher : Badan Pengawas Obat dan Makanan

Potensi ancaman masuknya Obat dan Makanan tanpa izin edar masih menunjukan menunjukan dominasi yang mengkhawatirkan, dengan rata-rata per-tahun sebesar 70,5% dari 13 jenis perkara Obat dan Makanan pada periode tahun 2015-2017. Pemahaman PPNS BPOM menjadi krusial pada fungsi penindakan. Penelitian ini bertujuan untuk menganalisis pemahaman PPNS BPOM dan memformulasikan strategi yang tepat dalam pengawasan post border. Penelitian menggunakan pendekatan mixed methods dengan metode survei dan studi kasus. Regulatory Impact Analysis (RIA) Framework digunakan sebagai pola pikir dengan pendekatan analisa intelijen. Hasil penelitian menunjukan bahwa pemahaman PPNS BPOM masih harus ditingkatkan hingga diperoleh pemahaman yang sama dan merata di seluruh Indonesia. Asimetris informasi antar BPOM dan DJBC dihilangkan dengan melakukan pelatihan bersama. Kesadaran akan pentingnya kerjasama dengan DJBC dan kebutuhan informasi sebelum Obat dan Makanan keluar dari kawasan pabean menunjukan perlunya langkah strategi kolaborasi pengawasan post border. Pertukaran informasi intelijen merupakan strategi prioritas pengawasan post border yang dapat dibangun dari kolaborasi BPOM dan DJBC. Potential threat of non-registered entry of imported Drug and Food showed alarming domination, with an average annual rate of 70.5% of 13 types of Drug and Food cases in the 2015-2017 period. Understanding of Indonesian-FDA investigator is crucial in the enforcement function. This study aims to analyze the understanding of Indonesian-FDA investigator and formulate an efficient and effective control strategy. The study uses a mixed-methods approach using survey methods and case studies. The Regulatory Impact Analysis (RIA) Framework is used as a mindset with an intelligence analysis approach. The results show that the understanding of Indonesian-FDA investigators still needs to be improved so that an understanding is equal and evenly distributed throughout Indonesia. Asymmetric information between Indonesian-FDA and DGCE is eliminated by conducting joint training. Awareness of the importance of collaboration with DGCE and the need for information before Drug and Food leave the customs area shows the need for collaborative post-border surveillance strategic steps. The exchange of intelligence information is a priority strategy for post border control that can be built from the collaboration of Indonesian-FDA and DGCE.

A Review: Induced Pluripotent Stem Cells (iPS) Therapy Is the Best Method to Cure Non-Communicable Diseases? Yola Eka Erwinda
Eruditio : Indonesia Journal of Food and Drug Safety Vol 1 No 1 (2020): Edisi Desember
Publisher : Badan Pengawas Obat dan Makanan

The potency of stem cells in treatment or therapy is widely known due the properties of stem cells to differentiate into specialized cell type in the body. Application stem cells in medicine and therapy is mostly used for alternative treatment of diseases that could not be cured using chemical or other biological drugs, such as non-communicable diseases. In general, stem cells are classified in three types, namely Adult Stem Cells (ASC), Human Embryonic Stem Cells (hESC), and Induced Pluripotent Stem Cells. Each type of the cells has advantages and drawbacks for application in medicine and therapy. This review investigates whether iPS is the best approach for non-communicable disease treatment among other stem cell types.

Peredaran Kosmetik Pemutih Ilegal di Indonesia dan Upaya Penanggulangannya Iin Febrianti Sende; Adin Wira Pramudita; M. Gafur Salafuddin; Edi Priyo Yunianto
Eruditio : Indonesia Journal of Food and Drug Safety Vol 1 No 1 (2020): Edisi Desember
Publisher : Badan Pengawas Obat dan Makanan

Whitening cosmetics are still popular in Indonesia, along with the stigma that white skin is idealized skin color. Woman with white skin acknowledges as beautiful woman. The increasing public demand for whitening cosmetics is exploited by crime offenders who produce and distribute illegal whitening cosmetics. The study was conducted by collecting inspection data and law enforcement data carried out by the Indonesian FDA and other criminal justice systems, direct research in the field, and online mapping through cyber patrol and Google Trends analysis to capture the distribution model of illegal whitening cosmetics in Indonesia, both those distributed offline as well as distributed online. The result of the study shows that illegal whitening cosmetics are produced then distributed offline and online in all provinces in Indonesia with various types of modus operandi, in line also with the high interest of searching for whitening cosmetics in online media. Illegal whitening cosmetics are known to have no marketing authorization and also contain prohibited ingredients, such as mercury, hydroquinone, tretinoin, and steroid. Many factors influence the supply chain stages of this illegal whitening cosmetics from upstream/supply (producers and distributors) to downstream/demand (consumers). Indonesian FDA must take the strategic step to minimize or reduce each of these factors, with repressive actions towards manufacturers and distributors, and preventive actions against consumers of illegal whitening cosmetics or through system/policy intervention.

Tren Baru Kosmetik "Share in Jar" Ilegal di Media Daring Iin Febrianti Sende; Edi Priyo Yunianto
Eruditio : Indonesia Journal of Food and Drug Safety Vol 1 No 1 (2020): Edisi Desember
Publisher : Badan Pengawas Obat dan Makanan

The Effect of Cosmetic formula on the skin is one of the main reasons for the new consumer to buy cosmetics. Before buy, new consumers feel confused about whether the cosmetic product is suitable for their skin or not. They need product tester. Unfortunately, not every cosmetic product sold in the market has a tester size. This condition led to the emergence of new illegal cosmetics trends in online media, namely share in jar. The concept of "share in a jar" is to divide (share) the content of the cosmetic product in (in) several small packaging (jar), with the aim that someone can buy and try the cosmetic product without buying the product in its original size. The study was conducted by online mapping and Google Trends analysis to review the phenomenon of cosmetics share in jar in online media, and also literature study of crime prevention strategies to provide intervention options that can be used. The results show that share in jar cosmetics are sold through various e-commerce and social media, and based on Google Trends analysis, the level of share in jar search has increased in the last 3,5 years. Most of them are import cosmetics in relatively high prices, and the most category is skincare cosmetics. Crime prevention strategies that can be done are through social crime prevention, situational crime prevention, and community-based crime prevention approaches, by intervening factors that influence cosmetics share in the jar distribution.

Bacteriocin, Antimicrobial as A New Natural Food Preservative: Its Potential and Challenges Sri Surati
Eruditio : Indonesia Journal of Food and Drug Safety Vol 1 No 1 (2020): Edisi Desember
Publisher : Badan Pengawas Obat dan Makanan

Improving food safety and quality remains a major challenge in worldwide. Modern society tends to choose the foods that are fresh tasting, free of chemical additives, rich in nutrients and has been introduced to minimally processed. Bacteriocins as new natural preservatives could be produced by Gram-positive bacteria and Gram-negative bacteria, even though it is mostly originated from Lactic Acid Bacteria (LAB). Bacteriocin-producing bacteria as well as bacteriocin has long been used in some countries as alternatives to replace chemical additives. The use of these antimicrobial agents has been proven effective in food manufacturing and distribution chain, especially in increasing shelf life of food products. Other potential from the use of bio-preservatives in various types of food is still huge. However, approval of bio-preservatives and their commercially applications is still limited. This study will review the selection criteria for bacteria used, the mechanism of action, its potential application in the food and pharmaceutical industries and its potential as an anti-cancer agent. In addition, this study will explore the main challenges faced including its stability and the possible risk of resistance to microorganisms. This review will also describe a series of processes for identification, characterization, and approval of the use of bacteriocins before they are commercially marketed. In addition, the safety issue of using bacteriocin-producing bacteria, especially as probiotics, also needs to be considered as a fundamental for quality control and the improvement of drug and food safety.

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Home Page

OAI Link

Editorial Team

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Contact Name
Listia Ningsih

Contact Email
listia.n@pom.go.id

Phone
+6281395105898

Journal Mail Official
eruditi@pom.go.id

Editorial Address
Gedung Batik Lt.5 - Badan POM Jl. Percetakan Negara No. 23 Kel. Johar Baru, Kec. Johar Baru, Jakarta Pusat 10560

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Listia Ningsih

Contact Email listia.n@pom.go.id

Phone +6281395105898

Journal Mail Official eruditi@pom.go.id

Editorial Address Gedung Batik Lt.5 - Badan POM Jl. Percetakan Negara No. 23 Kel. Johar Baru, Kec. Johar Baru, Jakarta Pusat 10560

Location Kota adm. jakarta pusat, Dki jakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Listia Ningsih

Contact Email
listia.n@pom.go.id

Phone
+6281395105898

Journal Mail Official
eruditi@pom.go.id

Editorial Address
Gedung Batik Lt.5 - Badan POM Jl. Percetakan Negara No. 23 Kel. Johar Baru, Kec. Johar Baru, Jakarta Pusat 10560

Location
Kota adm. jakarta pusat,

Dki jakarta

INDONESIA