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Rizky Akbar
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Department of Ophthalmology Jl. Jaksa Agung Suprapto No. 2, Malang, Indonesia
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INDONESIA
IJRETINA - International Journal of Retina
Published by Indonesian Vitreoretinal Society
ISSN : 26148684     EISSN : 26148536     DOI : https://doi.org/10.35479/ijretina.2023.vol006.iss0
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
International Journal of Retina is an open access journal, accepting article in English language from all over the worlds. The aims is to provide international researchers, doctors, and clinicians in the basic and clinical fields of ophthalmology, especially retina to publish the original article, case reports, or systematic review.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 109 Documents
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The Outcome of Vitrectomy in Acute Postoperative Endophthalmitis Sindy Boru Sembiring; Yulia Aziza; Gitalisa Andayani Adriono
International Journal of Retina Vol 1 No 1 (2018): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2018.vol001.iss001.12

Abstract

Introduction: Twenty years ago, the results of Endophthalmitis Vitrectomy Study (EVS) were adapted worldwide as the standard management of endophthalmitis. The study suggested that there was no benefit of performing vitrectomy for acute postoperative endophthalmitis, unless for patients who presents with visual acuity of light perception. However, vitrectomy with advanced technology and technique has been changed rapidly in the last decades; therefore, we need to reconsider its role. We conducted a study and the purpose of our study was to describe the indications for vitrectomy and the outcomes in acute postoperative endophthalmitis at Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Methods: Our study was a descriptive-retrospective case series. We reviewed clinical and microbiological records of all patients with clinical diagnosis of acute postoperative endophthalmitis who underwent vitrectomy in Cipto Mangunkusumo Hospital between 2007 and September 2015. Presenting visual acuity, visual outcome and complications were described. Result: Our study was a descriptive-retrospective case series. We reviewed clinical and microbiological records of all patients with clinical diagnosis of acute postoperative endophthalmitis who underwent vitrectomy in Cipto Mangunkusumo Hospital between 2007 and September 2015. Presenting visual acuity, visual outcome and complications were described. Conclusion: An eight-year experience has taught us that vitrectomy offers better treatment outcome in the group with visual acuity of hand movement than those who only had visual acuity of light perception.
LEVELS OF HYPOXIA INDUCIBLE FACTOR-1α (HIF-1α) AND INTERCELLULAR ADHESION MOLECULE-1 (ICAM-1) AFTER INTRAVITREAL BEVACIZUMAB IN PROLIFERATIVE DIABETIC RETINOPATHY Ressa Yuneta; Tjahjono Darminto Gondhowiardjo; Rahayuningsih Dharma; Sri Widia A. Jusman; Joedo Prihartono; Andi Arus Victor
International Journal of Retina Vol 2 No 1 (2019): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2019.vol002.iss001.60

Abstract

Purpose: to assess the levels of Hypoxia-inducible factor-1α (HIF-1α) and intercellular adhesion molecule-1 (ICAM-1) in vitreous of proliferative diabetic retinopathy patients which were given intravitreal bevacizumab (IVB), as well as its relation to the central macular thickness (CMT) measured prior to vitrectomy. Methods: thirty-two eyes were randomized into two groups, one that received an IVB injection at 1-2 weeks previtrectomy and the control group which did not receive any injection. Measurement of HIF-1α and ICAM-1 was conducted using enzyme-linked immunosorbent assay (ELISA). The CMT were measured at the initial visit, prior to vitrectomy, and at follow up time (2, 4, and 12 weeks postoperatively) using Stratus OCT. Results: The mean levels of HIF-1α vitreous (ng/mg protein) in the control group and IVB respectively 0.020 (0.006; 0.077) and 0.029 (0.016; 0.21). Vitreous levels of ICAM-1 (ng /mL) in control group and IVB group were 20.10 (3.41; 40.16) and 23.33 (0.63; 68.5). The mean levels of HIF-1α and ICAM-1 vitreous obtained did not differ significantly between the two groups. Conclusion: The levels of HIF-1α and ICAM-1 in PDR patients do not decrease after one injection of intravitreal Bevacizumab 1-2 weeks prior to vitrectomy. The concentration of vitreous HIF-1α and ICAM-1 are not directly related to the CMT.
Comparison of oral rifampicin with observation alone in treatment of acute central serous Chorioretinopathy Anum Badar; Sadaf Khan; Sobia Usman Shah; Mohammad Tahir; Saman Babree
International Journal of Retina Vol 3 No 1 (2020): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2020.vol003.iss001.103

Abstract

Introduction: A randomized control trial To compare efficacy of oral rifampicin in terms of drying of macula and decrease macular thickness with observation alone in patients of acute central serous Chorioretinopathy done in Layton Rahmatulla Benevolent Trust (LRBT) Free Eye and Cancer Hospital, Lahore from January 2017 to June 2017 Methods: After getting approval from hospital Ethical committee 140 patients of CSR were included in the study. The demographic details were noted and patients were randomized by lottery methods in two groups (group A& B). Group-A was observed for spontaneous resolution, routine treatment started if no improvement noted after 6 weeks of observation alone. Group B was given oral rifampicin 600mg per day for four weeks with liver function tests being done before commencement of treatment and after 2 weeks. Oral rifampicin was stopped if patient developed deranged liver function tests. Patients were followed up at 4 weeks for macular dryness and decrease macular thickness on optical coherence tomography(OCT). All the readings were carried out and noted by single person in order to minimize bias. Results: A total of 140 patents, 70 in each group, were included In study with mean age 38.77+7.74 in Group-A and 39.14+7.97 years in Group-B. regarding gender distribution 65.71 %(n=46) in Group-A and 613.43%(n=43) in Group-B were male. Comparison of outcome of treatment of acute central serous chorioretinopathy with oral rifampicin vs observation showed that 18.57 %(n=13) in Group-A and 41.43%(n=29) in Group-B had dry macula. Conclusion: We concluded that there is a significant difference in drying of macula in acute central serous chorioretinopathy with Rifampicin versus observation alone.
Partial Thickness Sclerectomy for Uveal Effusion Syndrome in nanophthalmic eyes Simanta Khadka; Raghundandan Byanju; Sangita Pradhan; Saurav Piya; Sweta Singh; Ritesh Shah; Santosh Chaudhary
International Journal of Retina Vol 4 No 1 (2021): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2021.vol004.iss001.141

Abstract

Introduction: Nanophthalmos characterized by short axial length, high lens-to-eye ratio and thick sclera, is more prone to develop uveal effusion syndrome (UES). This rare entity can result in idiopathic exudative detachment of the choroid, ciliary body and retina. Abnormality in the scleral thickness with resultant obstruction of the vortex veins and reduced trans-scleral drainage of fluid is responsible for exudative retinal detachment (ERD). Methods: A retrospective study of UES in nanophthalmic patients treated with partial thickness sclerectomy in tertiary eye care centre from January 2015 to June 2019. Five eyes of five patients (four males and one female) with a diagnosis of nanophthalmos suffered from angle closure glaucoma associated with ERD. Raised intra-ocular pressure (IOP) not amenable to conservative medical management were subjected to surgery. Lamellar sclerectomy was performed in two or more quadrants without drainage which was judged on the basis of maximum amount of exudative fluid present in the subsequent quadrants. Results: The average age at surgery was 39.2 years and the mean follow-up duration was 9.2 months (6 to 18 months). Revision sclerectomy was required in 2/5 (60%) eyes. The serous fluid gradually resolved and retina remained reattached at the end of final follow up. The useful vision was preserved and IOP was normalized. Conclusion: Nanophthalmic UES remains a challenging clinical entity. Partial thickness sclerectomy may be an effective option in the treatment of nanophthalmic UES, not amenable to the conventional medical management in a low resource setup.
THE DIFFERENCE OF QUALITY OF LIFE AND COGNITIVE FUNCTION BETWEEN PATIENTS WITH AND WITHOUT AGE-RELATED MACULA DEGENERATION (AMD) Bobby Kristianto; Anak Agung Ayu Sukartini Djelantik; Ari Andayani; Anak Agung Mas Putrawati Triningrat; I Gusti Ayu Made Juliari; I Gde Raka Widiana
International Journal of Retina Vol 4 No 2 (2021): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2021.vol004.iss002.168

Abstract

Introduction: To determine the difference in the quality of life and cognitive function in patients with and without AMD. Methods: This research is an observational analytic study, a prospective cross sectional study in the polyclinic of RSUP Sanglah, Denpasar. Result: Study samples’s total are 66 people selected by consecutive sampling with 33 people in the group with AMD, and 33 people in the group without AMD. The results of the study showed the average age of the group with AMD 68 years and the group without AMD 67 years old. Most of the male sex and residence in denpasar in both groups. Most AMD with the wet type by 60.6 %. On the measurement of quality of life, it showed decreasing in all subscale in the group with AMD compared to the group without AMD with total average 27.2 % and also decreasing in cognitive function measured by MMSE in the group of AMD compared to the group of non – AMD with 6.8%, even though the MMSE score of the groups are within normal limits. All these things stated significant differences (p<0.05) statistically. Conclusion: There are decreasing quality of life and cognitive function in AMD groupd compared to Non-AMD group which is needed more treatment and screening in the future.
CLINICAL MANIFESTATIONS AND CD4 COUNT CHARACTERISTICS OF PATIENTS WITH CYTOMEGALOVIRUS (CMV) RETINITIS Yunneke Renna Xaverina; Ovi Sofia
International Journal of Retina Vol 5 No 2 (2022): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2022.vol005.iss002.201

Abstract

Introduction: To describe the clinical manifestations and CD4 count characteristics of patients with cytomegalovirus (CMV) retinitis. Methods: This is a retrospective study of patients diagnosed with CMV retinitis at the Ophthalmology Outpatient Clinic at Dr. Saiful Anwar General Hospital, Malang, between January 2016 to December 2019. The patients’ characteristics and clinical data including gender, age, visual acuity, slit lamp biomicroscopy, indirect ophthalmoscope, and laboratory findings were collected from medical records. Result: Twenty-one eyes from thirteen patients with CMV retinitis were enrolled. The mean age was 30.9 ± 7.12 years, with 54% of them male. Bilateral lesions were observed in 62% of the patients, and the mean visual acuity during the initial visit was 1.50 ±1.07 log MAR. All patients presented with the classic form of CMV retinitis. Mean CD4 count when commencing treatment was 62.23 ±11.82 cells/µL with 77% below 50 cells/µL. Patients with CD4 count < 50 cells/µL mostly presented with posterior uveitis, bilateral lesion, and visual acuity ≤1.00 logMAR. Ten patients were given oral valganciclovir and antiretroviral therapy. Retinal detachment condition was noted at seven eyes. Candidiasis was the most presenting opportunistic infection. Conclusion: Cytomegalovirus retinitis was found in patients infected with AIDS with low CD4 counts. In this study, patients with CD4 counts of below 50 cells/µL tend to have more severe clinical presentations.
Giant Retinal Tear Management at Referral Eye Hospital Mia Purnama; Erwin Iskandar; Rova Virgana; Grimaldi Ihsan; Iwan Sovani; Arief Kartasasmita
International Journal of Retina Vol 1 No 1 (2018): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2018.vol001.iss001.5

Abstract

Introduction: to report the characteristics, management and outcome in giant retinal tear (GRT) associated retinal detachment patients at Cicendo Eye Hospital Methods: this retrospective study was performed on medical records who had undergone retinal detachment surgery between January 2014 and March 2017. Age, sex, etiologies, size of GRT, quadrant involvement, lens status, proliferative vitreo-retinopathy (PVR), managements and outcomes were evaluated in association with giant retinal tears Result: Twenty-six patients (23 males, 3 females) age between 11-59 years with follow up from 2 months to 18 months were enrolled in this study. Twenty-five eyes have retinal detachment with macular involvement and 11 patients had high myopia. Majority of patients had 90° of GRTs. Most retinal tears were located at temporal quadrant (73%). Nineteen patients had undergone pars plana vitrectomy (PPV) and 7 patients had combined PPV with encircling buckle. Fifteen patients had used heavy liquid, 24 patients had silicon oil and 2 had gas tamponade. Intraoperative complications included lens trauma, retinal slippage and choroidal detached were found in 1 eye respectively. Fourteen eyes had recurrent retinal detachment. At the last follow up, 14 patients had anatomically attached retina. Twelve patients had total retinal detachment and marked PVR. Five fellow eyes were treated with prophylactic laser. Visual acuity improved in 11 eyes. Conclusion: Giant retinal tears were more common in patients with high myopia. Management of GRT currently with PPV and PPV combined with encircling buckle. The success rate of anatomy and visual acuity was less than other previous studies
Polypoidal Choroidal Vasculopathy Mirza Metita; Yorihisa Kitagawa; Hiroyuki Shimada; Hiroyuki Nakashizuka
International Journal of Retina Vol 1 No 2 (2018): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2018.vol001.iss002.46

Abstract

Introduction: to report a case of PCV that has been successfully treated with intravitreal injection of t-PA, ranibizumab, and pneumatic displacement. Method: A 65 years old man presented with blurred vision of his right eye. No systemic abnormalities were found. Initial visual acuity RE was 6/18. Funduscopy examination showed submacular hemorrhage in posterior pole. OCTA, FA and ICG confirmed the diagnosis of PCV. We performed anterior chamber paracentesis and intravitreal injection of 0,05 ml t-PA, 0,05 ml ranibizumab, and 0,3 ml 100% C3F8 at a time in retrobulbar anesthesia. The patient was instructed to maintain face down positioning for 2 days. Results: We evaluated the visual acuity, central retinal thickness (CRT), and central pigment epithelial detachment (PED) thickness for 2 years. The visual acuity was increasing gradually from 6/18 to 6/6 in the first year. The hemorrhage was displaced completely, the CRT and central PED thickness were decreased. In the second year the patient had recurrence of PCV with serous retinal detachment and treated with intravitreal aflibercept. Conclusion: Combined treatment of intravitreal t-PA, ranibizumab, and C3F8 can be used as a beneficial therapy for PCV.
CLINICAL CHARACTERISTICS AND MANAGEMENT OF OCULAR TOXOPLASMOSIS Ovi Sofia; Rizqi Wahyu Hariyono
International Journal of Retina Vol 2 No 2 (2019): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2019.vol002.iss002.96

Abstract

Introduction: Ocular toxoplasmosis is a major cause of infectious posterior uveitis worldwide. There was no exact number of ocular toxoplasmosis prevalence in Indonesia, but Indonesia was considered to have high seroprevalence in Southeast Asian. This study is conducted to determine clinical characteristics and management of ocular toxoplasmosis at outpatient clinic of Dr. Saiful Anwar General Hospital, a tertiary referral hospital in Malang, East Java. Methods : This was retrospective study. We reviewed the medical records of patients with ocular toxoplasmosis and collected the data associated with age, sex, laterality, visual outcome, type of lesions, serum serological titers, therapeutic regimens, and complications. Result : There were 48 eyes from 38 patients included in this study, mostly were female (66%) with mean age was 33,5 years. Unilateral infection (71%) was more frequent than bilateral cases (39%). Active lesions were found more than cicatrical lesions (56,25%). Most patients with active diseases had unilateral lesion (87,5%). The most common presenting complain was blurred vision (73%). Most of lesions (22 eyes; 81,4%) were located on macular region. All of patients have positive IgG antitoxoplasma serum. There were 22 patients received oral Trimethoprim-Sulfamethoxazole and steroid. Visual acuity improved in 6 patients at the end of follow-up period. Complications of retinal detachment and choroidal neovascularization were found in 3 patients. Conclusion : Active ocular toxoplasmosis is more likely to be unilateral infection with main presenting complain is blurred vision. Most of our patients show good responses to oral trimethoprim-sulfamethoxazole and steroid.
Optical Coherence Tomography Angiography to detect non-exudative neovascular age-related macular degeneration mimicking chronic central serous chorioretinopathy. Manuel A P Vilela
International Journal of Retina Vol 3 No 2 (2020): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2020.vol003.iss002.104

Abstract

Chronic central serous chorioretinopathy (cCSC) can produce an overlap of signs that can be difficult to distinguish from cases with non-exudative neovascular age-related macular degeneration (nneAMD). Around 2-10% of the patients with cCSC will develop neovascularization. Sometimes both diseases could be present at the same individual. The purpose of this narrative review is to discuss the current information concerning the signs in OCT angiography that eventually could help to differentiate these situations and analyze the best diagnostic evidence.

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