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Herin Setianingsih
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putra.abdullah@hangtuah.ac.id
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Jl. Gadung no. 1 Komplek Barat RSAL dr. Ramelan Surabaya 60111 Jawa Timur
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Surabaya Biomedical Journal
Published by Universitas Hang Tuah
ISSN : -     EISSN : 2808649X     DOI : https://doi.org/10.30649/sbj.v1i1
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
The scope of the journal includes: - marine medicine - hyperbaric medicine - general medicine - dentistry - nursing - related health sciences - pharmacy
Arjuna Subject : Kedokteran - Biokimia, Kedokteran
Articles 7 Documents
 1 
Search results for , issue "Vol 3 No 1 (2023): September 2023" : 7 Documents clear
Demam Berdarah Dengue dengan Perdarahan Spontan Muhammad Anas; Aty Firsiyanti; Yusian Eri Fitria; Hassita Nadia Silkviana; Putri Naula Abbas; Alshafiera Azayyana M.S; Moch Frando G.E; Ulaa Haniifah
Surabaya Biomedical Journal Vol 3 No 1 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.54

Abstract

Abstrak Pendahuluan: Dengue Hemorrhagic Fever (DHF) merupakan salah satu infeksi yang sering terjadi di negara tropis utamanya Indonesia dan banyak menyebabkan kematian. DHF merupakan bagian dari Infeksi Virus Dengue yang mmkiliki klasifikasi lain. Tanda klinis DHF adalah demam tinggi, penurunan trombosit dan leukosit, bisa atau tidak ditemukan adanya perdarahan spontan. Laporan Kasus: Pasien anak laki – laki usia 15 tahun rujukan dari PKU Sumberaji dengan keluhan demam, keringat dingin, BAB lembek, mimisan, mual muntah dan nyeri kepala. Pembahasan: Dengue Hemorrhagic Fever (DHF) merupakan salah satu bagian dari Infeksi Virus Dengue yang disebabkan oleh virus DEN 1-4, vectornya adalah nyamuk Aedes Aegypti. Manifestasi klinis dapat berbeda – beda tiap klasifikasinya, kesamaan hanya ada di keluhan demam tinggi. Klasifikasi lain bisa berupa Undifferentiated Fever, Dengue Fever, DHF grade 1-IV, Dengue Shock Syndrome. Klasifikasi ini juga digunakan untuk menentukan terapi dan prognosis penyakit Kata kunci: Demam, Dengue Fever, Infeksi Virus Dengue, Dengue Hemorrhagic Fever. Abstract Introduction: Dengue Hemorrhagic Fever (DHF) is an infection that often occurs in tropical countries, especially Indonesia and causes many deaths. DHF is part of Dengue Virus Infection which has another classification. Clinical signs of DHF are high fever, decreased platelets and leukocytes, spontaneous bleeding may or may not be found. Case Report: A 15-year-old male patient referred from PKU Sumberaji with complaints of fever, cold sweat, loose bowel movements, nosebleeds, nausea, vomiting and headaches. Discussion: Dengue Hemorrhagic Fever (DHF) is a part of Dengue Virus Infection caused by the DEN 1-4 virus, the vector of which is the Aedes Aegypti mosquito. Clinical manifestations can be different for each classification, similarities are only in complaints of high fever. Another classification can be Undifferentiated Fever, Dengue Fever, DHF grade 1-IV, Dengue Shock Syndrome. This classification is also used to determine therapy and disease prognosis Keyword: Fever, Dengue Fever, Dengue Virus Infection, Dengue Hemorrhagic Fever
Studi Literatur Prognosis Pasien COVID-19 dengan Komplikasi Stroke Sofia Devi Anjani
Surabaya Biomedical Journal Vol 3 No 1 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.71

Abstract

Tujuan Penelitian: COVID-19 telah menjadi ancaman kesehatan global sejak ditemukannya pasien yang pertama kali terpapar pada Desember 2019 di Wuhan, Cina. Salah satu komplikasi serius neurologis terkait COVID-19 adalah stroke. Penelitian ini bertujuan untuk membahas prognosis pada pasien COVID-19 dengan komplikasi stroke. Metode: Penelitian studi literatur ini menggunakan 20 artikel dengan kriteria inklusi artikel jurnal internasional terindeks Scimago yang dipublikasian pada tahun 2018 hingga 2022. Artikel pada penelitian ini diambil melalui Google Scholar, PubMed, dan ScienceDirect. Hasil: Subtipe stroke tersering pada pasien COVID-19 adalah stroke iskemik dan diikuti oleh stroke hemoragik. Insiden kumulatif pasien COVID-19 dengan stroke iskemik menunjukkan perawatan di ICU yang lebih tinggi dibandingkan pasien COVID-19 dengan stroke hemoragik yang lebih jarang ditemukan diantara pasien rawat inap tetapi memiliki angka kematian yang lebih tinggi Kesimpulan: Stroke hemoragik pada pasien COVID-19 mengindikasikan prognosis yang lebih buruk dengan angka kematian yang tinggi dibandingkan dengan stroke iskemik pada pasien COVID-19 yang memiliki prognosis yang lebih baik dengan angka pasien pulih yang lebih banyak.
EFEKTIVITAS DAN EFEK SAMPING PENGGUNAAN IUD PASCA PLASENTA DI RSPAL DR. RAMELAN PERIODE JANUARI 2019 – DESEMBER 2021 Anisha Farah Suroso
Surabaya Biomedical Journal Vol 3 No 1 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.82

Abstract

Background : In 2020 Indonesia has experienced an increase in population which has become a problem in Indonesia. In preventing the population explosion, the government established a program, named Family Planning (KB). In the family planning program, there is a contraceptive method, named the Intra Uterine Device (IUD). Post-placental IUD contraception is a safe, easy dan effective contraceptive for inserting a long-term intrauterine contraceptive device (IUD) with convenience in use, dan ease dan lower side effects. Study aims : To determine the effectiveness dan side effects of using a post-placental IUD at Dr Ramelan Hospital for the period January 2019 – December 2021. Methods : The research design was a descriptive research design using quantitative methods. Researchers used secondary data in the form of electronic medical records (SIMRS) with a total sample of 88 people. The data examined included age, parity, duration of use of the post-placental IUD, the effectiveness of the post-placental IUD, the side effects of the post-placental IUD such as: pain, menstrual disorders, bleeding, dan IUD removal. Results : From a total sample of 88 people, the effectiveness of the post-placental IUD was 96.6%, dan the side effects that occurred were frequent pain in 26 people (29.5%), menstrual disorders in 33 people (37.5%) ), bleeding disorders in 21 people (23.9%), dan removing the IUD in 31 people (35.2%). Conclusion : The effectiveness of the post-placental IUD is 96.6%, dan the side effects that occur during post-placental IUD users are pain, menstrual disorders, bleeding, dan IUD removal.
KARAKTERISTIK DAN PERJALANAN DERMATITIS ATOPIK DENGAN RIWAYAT ASMA BRONKIAL Anisa Dwi Abelia
Surabaya Biomedical Journal Vol 3 No 1 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.85

Abstract

Atopic dermatitis is a chronic inflammatory skin disease that begins primarily in childhood with a mixed natural history. atopic dermatitis has increased over the past 30 years. It is currently estimated that 10-20% of children and 1-3% of adults in developed countries are affected by atopic dermatitis. Knowing the characteristics and course of atopic dermatitis with a history of bronchial asthma based on: Gender, age, history of atopy, signs and symptoms, location of lesions and disease course and development including disease onset. This research method uses literature study. Where this research contains explanations, elaboration of theories, findings, and search results regarding topics written from books, journals, articles and research reports. Researcher questions and topics are matched with specific keywords for research. These keywords are then used to search for articles on Google Scholar, PubMed, and Science Direct. These articles are then sorted and categorized into PRISMA diagrams. Then proceed with filtering and indexing articles on Scimago or SINTA. It was found that 15 of these indexing results were found in Scimago or SINTA. Characteristics of atopic dermatitis with a history of bronchial asthma found the majority to occur in women. The onset begins in childhood, gets better in adolescence and then gets worse in adulthood. The characteristic lesions of atopic dermatitis, in which one reported dry and itchy skin to erythema, skin peeling, skin thickening, secretions, hyperpigmentation, and lichenification. There is an increase in IgE and pro-Th2 cytokine levels, based on the therapy the majority indicate the use of corticosteroids. Keywords : atopic dermatitis, asthma bronchiale, allergy
Patin sebagai sumber omega 3 untuk menurunkan faktor resiko terjadinya MAFLD karena DM tipe 2
Surabaya Biomedical Journal Vol 3 No 1 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.114

Abstract

Diet asam lemak tak jenuh ganda (PUFA) telah diteliti dan terbukti dapat memodulasi peradangan, namun, hanya sedikit beberapa penelitian yang fokusnya pada patobiologi PUFA dengan menggunakan diet isokalori dan isolipid namun belum dapat dijelaskan apakah patologi terkait tersebut disebabkan oleh komposisi diet PUFA, metabolisme lipid, atau obesitas, karena sebagian besar penelitian membandingkan diet dengan yang diberi makan ad libitum. Stres oksidatif dan mitokondria hati berperan dalam patogenesis penyakit hati berlemak nonalcohol. Omega-3 PUFA memiliki peran protektif yang potensial terhadap kerusakan sel oksidatif yang diinduksi ROS pada tikus organ, terutama di hati. Atenuasi hepatic fibrosis oleh EPA (asam eicosapentaenoic) secara signifikan berhubungan dengan kadar ROS hati. EPA juga menekan peningkatan kadar ROS hati dan penurunan penanda oksidatif serum, seperti 8-isoprostan dan feritin. Ikan patin memiliki kandungan asam lemak tak jenuh ganda omega 3 serta selenium yang merupakan antioksidan sehingga dapat menghambat terjadinya progresifisitas kejadian NAFLD maupun MAFLD. Mekanismenya antara lain melalui jalur penghambatan stress oksidatif yang merupakan patofisiologi terjadinya NAFLD maupun MAFLD.
PENGARUH OBESITAS TERHADAP KARAKTERISTIK POLA BERJALAN : LITERATURE REVIEW
Surabaya Biomedical Journal Vol 3 No 1 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.115

Abstract

Obesity is a global health problem with increasing prevalence worldwide. One aspect of concern is how obesity can affect an individual's gait characteristics, leading to musculoskeletal disorders. Numerous studies have explored the gait characteristics experienced by individuals with obesity. The objective of this literature review is to provide further information on the gait characteristics of individuals with obesity, which can be utilized for the prevention of obesity-related musculoskeletal disorders. The methodology employed in this study is a literature review, creating conclusions from selected data sources from various national and international journals published between 2011 and 2021. The findings reveal that obesity can lead to decreased balance, reduced walking speed, and influence several gait characteristic parameters, such as changes in step length and width, stride length, as well as various angles formed by the knee and ankle joints during walking, resulting in a distinct gait pattern compared to normal gait. Therefore, it can be concluded that individuals with obesity are prone to exhibit an altered gait pattern, which can potentially contribute to musculoskeletal problems such as osteoarthritis.
SEL POLIMORFONUKLEAR MEMBERAN PLASENTA PADA KASUS KPP DI RSPAL SURABAYA
Surabaya Biomedical Journal Vol 3 No 1 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v3i1.117

Abstract

ABSTRAK Ketuban pecah dini (KPD) adalah pecahnya selaput ketuban sebelum adanya tanda-tanda persalinan, dan dapat terjadi pada kehamilan aterm maupun pada hehamilan prematur. Inflamasi merupakan kondisi umum yang mendasari terjadinya KPD. Desain penelitian ini adalah penelitian cross sectional deskriptif observasional. Sampel penelitian ini adalah sampel jenuh yang diambil selama 4 bulan (bulan Agustus-November 2019). Bahan pemeriksaan berupa selaput ketuban yang diambil saat persalinan pasien-pasien yang didiagnosis PROM di RSPAL Surabaya. Kemudian dilakukan pemeriksaan patologi anatomi untuk melihat sebaran sel radang PMN. Total sampel adalah 20 pasien. Berdasarkan hasil pemeriksaan histopatologi didapatkan bahwa 11 dari 20 (55%) selaput janin mengandung sel radang polimorfonuklear dan 9 (45%) sisanya tidak mengandung sel radang polimorfonuklear. Lebih dari separuh kasus pecahnya selaput ketuban disebabkan oleh terjadinya keradangan pada selaput ketuban. Kata kunci: ketuban pecah dini, sel radang, sel inflamasi, polimorfonuklear, histopatologi. ABSTRACT Premature of membranes (PROM) is the rupture tht amniotic membranes before there are signs of labor, and can occur i8n term pregnancies as well as in premature pregnancy. Inflammation is a common condition that underlies the PROM. The design of this research is a cross sectional descriptive study. Examination material in the form of amniotic membranes taken during delivery of patients diagnosed with PROM at RSPAL Surabaya. The methods sampling is a saturated sample taken for 4 months (August – November 2019), then an anatomic pathology analysis was carried out to see the distribution of PMN inflammatory cells. The total sample is 20 patients. Based on the results histopathological examination, it was found that 55% fetal membranes contained polymorphonuclear cells and 45% without polymorphonuclear cells. More than half of the cases of rupture membranes are caused by inflammation. Keywords: premature rupture of the membranes, inflammatory cells, polymorphonuclear cell, histopathology.

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