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Bioactivities
Published by Pandawa Institute
ISSN : 2963654X     EISSN : 2963654X     DOI : https://doi.org/10.47352/bioactivities
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology
Bioactivities is a double-blind peer-reviewed journal for research activity on bioactivities of materials or compounds. This journal aims to provide a means for sustained discussion of relevant issues that fall within the focus and scopes of the journal which can be examined empirically in the following fields: 1) antioxidant; 2) antibacterial; 3) antifungal; 4) antiviral; 5) antibiotic; 6) anticancer; 7) antitumoral; 8) anti-fouling; 9) anti-inflammatory; 10) antihypertensive; 11) anti-obesity; 12) antiproliferative; 13) anti-opioid; and 14) biosorption. The Bioactivities is an open-access journal containing original research articles, review articles, and short communications in the areas related to bioactivities. The Bioactivities publishes 2 issues in a year in June (first issue) and December (second issue). This journal has adopted a double-blind reviewing policy whereby the referees and author(s) remain anonymous throughout the process.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol. 1 No. 1 (2023): Bioactivities" : 5 Documents clear
Green Synthesis of Silver Nanoparticles using Egyptian Date Palm (Phoenix dactylifera L.) Seeds and Their Antibacterial Activity Assessment Mohamed E Abdel-Alim; Karam Samaan; Dominique Guillaume; Hashim Amla
Bioactivities Vol. 1 No. 1 (2023): Bioactivities
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/bioactivities.2963-654X.180

Abstract

A simple, cost-effective and eco-friendly synthesis technique of silver nanoparticles (AgNPs) using the aqueous extracts of Egyptian date palm (Phoenix dactylifera L.) seeds and their antibacterial activity assessment have been conducted. Theaqueous extract was used as reducing and stabilizer agents in the synthesis of AgNPs. Characterization of AgNPs was done using different methods including ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared (FTIR), field emission-scanning electron microscope (FE-SEM), and X-ray diffraction (XRD). UV-Vis spectrum of the aqueous medium containing AgNPs showed an absorption peak at around 432 nm. FTIR spectra had shown that the biomolecules were responsible for the reduction and capping agents of AgNPs. XRD study showed the particles to be crystalline with a face-centered cubic (fcc) structure. The AgNPs exhibited significant anti-bacterial activity against Bacillus subtilis, Escherichia coli, Enterococcus faecalis, and Staphylococcus aureus. Overall, these findings suggest that biosynthesized AgNPs may be used as a potential therapeutic formulation against bacterial infections.
Biosorption of Pd(II) from Aqueous Solution using Leaves of Moringa oleifera as a Low-cost Biosorbent Dinani Amorim; Bruno Costa; Denis Martinez
Bioactivities Vol. 1 No. 1 (2023): Bioactivities
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/bioactivities.2963-654X.181

Abstract

Palladium ion (Pd(II)) is one of the hazardous metal pollutants commonly found in industrial effluents and poses severe environmental and human health impacts. The present study has chosen the leaves of Moringa oleifera (L-MO) as a potential biosorbent for removing Pd(II) from the aqueous solution. Various parameters such as pH, biosorbent dose, and initial Pd(II) concentration were optimized for maximum removal of Pd(II) using standard protocols. The Fourier-transform infrared spectroscopy study was performed to identify the functional groups involved in Pd(II) biosorption mechanism. The analysis of FTIR spectra confirmed the involvement of functional groups such as C–O, C=O, C–H, and O–H in the biosorption of Pd(II) on the surface of L-MO. The biosorption of Pd(II) was highest at pH 6. The sorption equilibrium data were well-fitted with the Langmuir isotherm model (R2 = 0.9896). The highest adsorption capacity of L-MO was 41.15 mg/g. It is concluded that the L-MO could be used as a potentially low-cost novel biosorbent to remove Pd(II) from contaminated water.
Antibacterial Activity of Several Types of Weed Extracts on The Growth of Escherichia coli Dwi Nur Rikhma Sari; Septarini Dian Anitasari; Intan Choirul Uliyah
Bioactivities Vol. 1 No. 1 (2023): Bioactivities
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/bioactivities.2963-654X.182

Abstract

Escherichia coli is a type of Gram-negative bacteria that is commonly found in the human digestive tract. It has been reported as one of the bacteria that has been resistant to several antibiotics. This study aims to determine four (4) types of weed extracts that are considered but have not been used as antibacterial compounds against E. coli. This experimental study used a completely randomized design with several types of plant extracts, namely Acalypha indica L., Ageratum conyzoides, Phyllanthus niruri L., and Amaranthus spinosios at various concentrations (0, 50, and 100%). The results showed that the plant extract of A. indica L. had the ability as an antibacterial against the growth of E. coli at concentrations of 50% (1.41 ± 0.12) and 100% (1.53 ± 0.01) compared to other extracts. Meanwhile, the lowest average diameter of the inhibition zone for E. coli bacteria was found in the treatment of A. spinosios grass leaf extract 50% (1.17 ± 0.05).
A Comparative Study on Phytochemical Screening and Antioxidant Activity of Aqueous Extract from Various Parts of Bauhinia purpurea Tin Mar Htay; Kyi Kyi Sann; Hazwan Haini
Bioactivities Vol. 1 No. 1 (2023): Bioactivities
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/bioactivities.2963-654X.183

Abstract

In this study, we conducted a comparative investigation into the phytochemical screening and antioxidant activity of aqueous extracts from various parts of the Bauhinia purpurea plant, including leaf, flower, stem bark, and root. The qualitative analysis was performed to screen the phytochemical content of each extract, followed by quantitative analysis to determine the total phenolic and total flavonoid contents. Our findings revealed that different parts of the B. purpureaplant yielded distinct natural products upon extraction. Both the leaf and flower extracts contained alkaloids, flavonoids, saponins, carbohydrates, polyphenols, and phenolics. On the other hand, the aqueous extracts of the stem barks and rootparts of B. purpurea only contained alkaloids, flavonoids, and phenolics. Consistent with the phytochemical assay, the flower extract exhibited the highest total phenolic content (40.14 ± 0.65 µg/mL GAE) and the highest flavonoid content (387.57 ± 0.63 µg/mL CE) compared to the other parts. Consequently, the flower extract displayed the highest antioxidant activity (51.76 ± 0.32%) with DPPH radical assay, closely approaching the antioxidant activity of ascorbic acid (70.54 ± 0.51%), which served as the positive control. This significant finding highlights the potential of the B. purpurea flower as a potent source of antioxidant agents for future applications.
Effectiveness of the Combination of Green Betel Leaf Extract (Piper betle) and Mint Leaf (Mentha piperita) as Antibacterials against Streptococcus mutans Inka Kandida; Mayang Tari; Awalul Fatiqin
Bioactivities Vol. 1 No. 1 (2023): Bioactivities
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/bioactivities.2963-654X.184

Abstract

The content of betel leaf (Piper betle) includes essential oils, alkaloids, flavonoids, phenols, and steroids. Flavonoid compounds in P. betle show a mechanism of action in damaging bacterial cell proteins and disrupting irreparable membranes. On the other hand, mint leaves (Mentha piperita) contain essential oil ranging from 1-2%, with menthol content around 80-90%, as well as mentone, d-piperitone, hexanol phenyl acetate, ethyl amyl carbinol, and neomenthol. The aim of this study is to determine the effectiveness of the combination of P. betle extract and M. piperita extract in inhibiting the growth of Streptococcus mutans (S. mutans) bacteria using the well diffusion method. Extraction of P. betle and M. piperita extracts were performed using the maceration method. The extraction results showed a yield of 24.94% for the P. betle extract and 35.39% for the M. piperita extract. The antibacterial testing against S. mutans showed an inhibition zone of 21.83 ± 1.58 mm for the single P. betle extract (ML), 11.2 ± 1.00 mm for the M. piperita (GBL), and 11.76 ± 0.57 mm for the combination extract (GBL/ML). There is an influence of the combination of P. betle and M. piperita extracts on the antibacterial effectiveness against S. mutans, although the inhibition zone of the P. betle is larger, measuring 21.83 ± 1.58 mm.

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