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Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute
Published by Universitas Indonesia
ISSN : -     EISSN : 28284070     DOI : https://doi.org/10.69951/proceedingsbookoficeonime
Core Subject : Health, Science,
Health Professions Medicine & Pharmacology Neuroscience Public Health
This proceeding book encompasses various themes within the realm of general medicine. Selected articles from the International Conference and Exhibition of The Indonesian Medical Education Research Institute undergo peer review and editorial management before being published as an open-access digital proceeding book. The published articles include original pieces, case reports, case series, systematic reviews, narrative reviews, and technical notes.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 24 Documents
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The Quality of Life and the Hypoxia Indicator in Survivor of Pediatric Intensive Care Unit in the University of Sumatera Utara Hospital Ririe Fachrina Malisie; Ika Citra Dewi Tanjung
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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The technology development for care and management in intensive care units reduces mortality and increases survivors' survival rate and life expectancy. A significant decrease in mortality rate in patients was related to mechanical ventilation. The hypoxia degree and severity of the respiratory distress are the increase of PaO2/FiO2 ratio and decrease of oxygenation index as predictors of oxygenation sufficiency in arterial blood supply to body tissues. The critical parameter of intensive care unit survivors' quality of life is the Pediatric Quality of Life (PedsQL) Inventory score after survival from the pediatric intensive care unit (PICU). During six months of research observation, eight patients died, and 13 patients survived among 68 patients admitted to pediatric intensive care unit who have ventilatory support. The mean PaO2/FiO2 ratio (PFR) in pediatric intensive care survivors who underwent mechanical ventilation was 285, and the mean Oxygenation Index (OI) was 5.07. There was no relationship between PFR and OI with PedsQL score in this study, but we have found a significant correlation between PedsQL and the duration of mechanical ventilation and length of stay in the intensive care unit. The longer mechanical ventilation duration and length of stay in PICU, the lower the pediatric quality of life score.
The Role of Cold Water Immersion as a Post-Exercise Recovery Method for Recreational Athlete Based on Creatine Kinase and Vertical Jump: A Randomised Trial Febianto Nurmansyach; Nani Cahyani Sudarsono; Yusra Yusra
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Background: Recreational sports have a positive influence on health. However, there will be a concern if the training intensity and volume increase without proper recovery. Cold water immersion has been known as one of the post-exercise recovery methods. Assessment of creatine kinase and vertical jump can be used to monitor the condition of post-exercise recovery. Aim: To evaluate the role of cold water immersion based on creatine kinase and vertical jump. Method: Twenty subjects were randomized to the cold water immersion or passive recovery group. Creatine kinase and vertical jump were measured as a baseline, followed by fatigue protocol (circuit training in gym) and recovery protocol according to each group. The creatine kinase and vertical jump were monitored in three consecutive periods; post-exercise recovery, 24-hour, and 48-hour post-exercise. The mean difference within groups and between groups of creatine kinase and the vertical jump was analyzed using repeated Anova + post-hoc Bonferroni test and T-test, respectively. Results: The intervention group showed faster recovery than the control group at 24-hour post-exercise based on vertical jump. Intervention group had higher vertical jump (p = 0,039) at 24-hour assessment. The intervention group showed faster recovery at 48-hour post-exercise than the control group on creatine kinase. There were also lower (p <0,01) creatine kinase in the intervention group at 48-hour post-exercise measurement. Conclusion: The use of cold water immersion is recommended as a post-exercise recovery method for the recreational athlete after high-volume and high-intensity training.
E-Learning Readiness and Job Stressor of Elementary School Teachers in the Covid-19 Pandemic Riani Dwianasari; Aria Kekalih; Dewi Yunia Fitriani; Dewi Sumaryani Soemarko; Ahmad Fuadi
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Background: E-learning readiness became a new workload for teachers during the Covid-19 pandemic because of the obligatory online teaching. E-learning readiness comprises four factors: the readiness of technology, innovation, people, and self-development; and it might cause job stressors and affect teachers' performance. The research objective was to explore job stressors that influence teachers the most and how they might be associated with E-learning readiness. Method: The cross-sectional method assessed 186 teachers from public and private elementary schools in the urban city area in Jakarta. The data obtained from questionnaires: Teacher Stress Inventory (TSI) Boyle and E-learning Readiness (ELR) Aydin and Tasci. TSI assessed teachers' job stressors in five main components: workload, student behavior, professional recognition, time and resources, and interpersonal relationships. Results: Most teachers perceived readiness at e-learning (84.9%). E-learning readiness was a profound problem for female and non-classroom teachers. The dominant job stressors for teachers were workload (27%), professional recognition (22%), time and resources (21%), and student behavior (21%). The number of students influenced workload and professional recognition. Self-development was the prominent e-learning readiness factor associated with teacher job stressors, especially professional recognition. Conclusions: In urban areas like Jakarta, fifteen percent of teachers remain unprepared for e-learning teaching. The unpreparedness was related to the female gender and non-classroom teachers, who need e-learning skills training to improve their readiness and control job stressors for better teaching performance in a prolonged pandemic situation.
Curcumin as Adjuvant Therapy in Mild-Moderate Covid 19 Ronald Winardi Kartika; Marcel Tendean; Bernard Jonathan Christian Yong; Katarina Dewi Sartika; Eka Widrian Suradji; Irsan Hasan
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Background: Coronavirus (Covid-19) has spread rapidly to more than 200 countries, including Indonesia. Adjuvant therapy of Vitamin C, D, Zinc has become beneficial for Covid-19 treatment to improve the immune system, while Curcumin is still not standard therapy. Curcumin can stimulate specific immune cells and can reduce oxidative stress. There is currently no scientific evidence showing that the addition of Curcumin can protect COVID-19, especially as an anti-inflammation and anticoagulant effect. Methods: This cross-sectional study was conducted at Ukrida Hospital from January -June 2021. The inclusion criteria are Mild-Moderate Covid-19 use on Curcumin and Supplement therapy ( Vitamin C, Vitamin D, and zinc). Data analyses with SPSS v.20 use Anova test and Kruskall Walis test. This study had been approved by The Institutional Board of the Faculty of Medicine Universitas Krida Wacana, Indonesia (No. 1053/SLKE-IM/UKKW/FKIK/KE/II/2021). Research Objectives: To see the effect of Curcumin as an additional therapy from Covid-19 by clinical and laboratory inflammation indicators of the usefulness of Curcumin are such as ratio neutrophil/lymphocyte, ratio platelet/lymphocyte, erythrocyte sedimentation rate (ESR), C-Reactive Protein ( CRP), and D Dimer. Results: There were 246 cases, with 62.6% male and 56.5% female taking Curcumin. Curcumin has a good effect in reducing inflammation and coagulation in mild-moderate Covid-19. Patient who got Curcumin or without Curcumin as additional supplement therapy shows patient that got Curcumin has decreased inflammatory markers N/L ratio (p = 0.041), P/L ratio (p = 0.040), ESR (p = 0.013 ), and CRP ( p= 0.045). Curcumin also has an anticoagulant effect that shows a decrease of D-Dimer ( p= 0.020). Conclusion: Curcumin is beneficial in mild-moderate Covid-19 as an anti-inflammatory and anticoagulant.
Assessment of Hand Function as a Tool for Planning a Rehabilitation Program in Scleroderma Patient a Case Report Virginia Ainurridlo Nugroho; Muhammad Ridwan; Rahmad Rahmad
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Scleroderma causes reduced versatility and the snugness of the skin due to cutaneous thickening and solidification (sclerosis). Scleroderma affects productivity, particularly hand-related work. A 29 years old man with scleroderma presented pain, contracture of his wrists and fingers, sclerodactyly, hardened skin, tightness, as well as shiny and dry skin. These manifestations decrease hand function, resulting in difficulty doing ADL and his job as a porter. Scleroderma was diagnosed one month prior. The planned treatments are TENS to decrease the pain, USD and hand exercise to increase ROM, Mc mennel and connective tissue massage, home exercise, vocational modification and occupational therapy to maximize the hand function and ADL, and psychotherapy to increase his self-confidence. MHOQ and HAMIS are used to Monitor and evaluate hand function. The assessment before therapy are right side HAMIS : 12; left side HAMIS : 11; VAS : 4; MHQ (Hand function 35% ; ADL 60%; work 30%; Pain 90%; aesthetic 55%; satisfaction 45%) . After 2 month, right side HAMIS : 10; left side HAMIS : 10; VAS : 1 ; MHQ (Hand function 45% ; ADL 72%; work 40%; Pain 40%; aesthetic 55%; satisfaction 70%). HAMIS and MHOQ in scleroderma patients could be used as an accurate assessment tool for planning rehabilitation treatment. The questionnaires can be used as guidelines for modifying the appropriate assistive device for ADL and patient work.
The Potency of Vitamin C as Prevention and Therapy Against COVID-19 Vitamin C Against COVID-19: A Systematic Review Mirasari Putri; Raden Aliya T. M. Djajanagara; Mas Rizky A. A. Syamsunarno
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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COVID-19 affects more than 200 countries worldwide. This viral infection leads to systemic inflammation elevation, characterized by high pro-inflammatory cytokines and oxidative damage. Vitamin C (VC) functions as an antioxidant by protecting cells from oxidative damage and suppressing the cytokine storm's phenomenon. This review highlighted the possibility of VC for prevention and management in COVID-19. This review is a scoping review; literature searching was conducted using PubMed, Clinical Key, and Google Scholar until August 2020. The keywords used were COVID-19 and vitamin C. Sixteen articles were further analyzed. The reviewed studies consist of seven case reports, three case series, three cohort studies, and three bioinformatics analyses. Some studies highlight the improvement of the COVID-19 patient's condition after VC treatment combined with other therapies. In bioinformatics studies, all studies showed the therapeutic targets for VC in COVID-19 involved in inflammation and oxidative damage pathway. The mechanisms of VC against COVID-19 are associated with oxidative damage by acting as reactive oxygen species (ROS) scavengers or depressing the ROS production and cytokine storm pathways by suppressing pro-inflammatory cytokines and apoptotic process stimulation following the neutrophil activation.
Case Series: Upper Airway Obstruction in Post-Acute Sequelae of Covid-19 (Pasc) Infection Due to Subglottic Stenosis Niken Ageng Rizki; Mushahigo Mushahigo; Mikael Fernando Santjoko
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Introduction: Post-Acute Sequelae of Covid-19 (PASC) manifestations can lead to upper airway obstruction, especially in patients with a history of intubation. Tracheal intubation can cause damage to the subglottic, the lowest part of the larynx; SARS-CoV-2 infection damages not only the pulmonary system but also the trachea. Subglottic stenosis is an abnormality in the form of narrowing of the airway in the subglottic area. This case series demonstrates that subglottic stenosis needs to be broadly understood as it contributes to PASC and should be considered an airway emergency. Objective: To emphasize the symptoms and signs of subglottic stenosis in patients with prolonged intubation and to show the correlation between the respiratory tract symptoms and factors contributing to airway obstruction. Case: We present 2 cases, one month after discharge from the hospital; a 55-year-old man and a 32-year-old man. both came with stridor, dyspnoea, intercostal retractions one month after being hospitalized due to covid-19 infection Conclusion: There are many symptoms and signs that may occur with shortness of breath, making diagnosis difficult. It is necessary to conduct investigations to establish the diagnosis and find the cause of shortness of breath. Early tracheostomy shortens days on the ventilator, intensive care unit, and hospital and should be considered for patients in the intensive care unit at risk for more than seven days of intubation.
Innate Immune Response in Non Alcoholic Fatty Liver Disease: An Overview of Alterations in TLR9, Macrophages, and TNFα Novianti Supriatna; Nurjati Chairani Siregar
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Non-Alcoholic Fatty Liver Disease (NAFLD) and Alcoholic Liver Disease (ALD) are two causes of chronic liver disease. In Indonesia, NAFLD is the most common case of hepatic disease for Indonesian people. Risk factors such as obesity, diabetes mellitus, and metabolic syndrome increase the risk of developing NAFLD. About 1.5 billion people worldwide suffer from fatty liver, with a prevalence of 25-30%. Hence, it will continue to increase sharply if risk factors or diseases are not mitigated with pharmacological treatment and diet. The innate immune response induces abnormalities in fatty liver, mediated by Kupffer cells and TLR9 (Toll-Like Receptor 9), leading to inflammation via proinflammatory cytokines, like TNFα. Hepatocyte injury releases signals in the form of mitochondrial DNA enclosed in microparticles, which travels into the plasma, and are then captured by TLR9. Activation of TLR9 on Kupffer cells is the starting point of the inflammatory process in the pathogenesis of NAFLD, and it triggers other immune responses that encourage the development of steatohepatitis until a more severe liver injury occurs. The latest study found that analysis is needed to determine the immunological mechanisms and therapeutic targets associated with inflammation in fatty liver disease as evidenced by various immunological approaches.
Significance Increased of Xanthine Oxidase Activity in Placenta with Pregnancy Complications of Preeclampsia and Gestational Diabetes Compared to Normal Gissi Novientri; Ani Retno Prijanti
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Certain risky complications in pregnancy are due to failure of pseudo-vasculogenesis of arteria spiralis, which leads to inadequate nutrition, hypoxia, and inflammation. These can be caused by eating disorders, stress, or other risk factors. Preeclampsia (PE) and Gestational Diabetes (GD) are pregnancy complications that are currently of concern. In Indonesia, the prevalence of PE reaches 3-10%, with a maternal mortality rate of 50%. Meanwhile, the prevalence of GD ranges from 1.9-3.6%, and half of GD patients are diagnosed with type 2 Diabetes Mellitus (DM) after 5-10 years of giving birth. Oxidative stress arises as a result of those pregnancy complications. Various studies have also been conducted to determine the pathways that produce reactive oxygen species (ROS), the leading causes of oxidative stress. Xanthine oxidase (XO) is an enzyme that contributes to ROS production. Uniquely this enzyme is the converted form of xanthine dehydrogenase (XDH), which plays a minimal role in ROS production. The conversion of XDH to XO significantly increased in PE and GD cases, characterized by increased XO activity in maternal and fetal circulation and placental tissue compared to normal pregnancies. This paper will describe the conversion mechanism of XDH to XO in PE and GD conditions and compare its enzyme activity to normal pregnancy.
Acupressure PC6 Self-Care for Hyperemesis Gravidarum during the Covid-19 Pandemic Yoshua Viventius; Hasan Mihardja; Wahyuningsih Djaali
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
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Introduction: Most pregnant women (50–90%) generally experience nausea and vomiting during pregnancy, which usually subsides at 16–20 weeks of gestation. Approximately 0.5–2 percent experience severe nausea and vomiting, known as HG, which necessitates hospitalization. Since 2.000, the Ministry of Health of the Republic of Indonesia has been developing acupressure self-care, among other things, by implementing acupressure training (Teknologi Tepat Guna – TTG) for mild complaints about health workers. Objective: This review discusses several studies that demonstrated the effect of acupressure on HG, as well as the mechanism of acupressure, the points used, and treatment strategies. Method: The Google Scholar and PubMed databases were searched for studies published between 2010 and 2020 on how acupressure affects HG using the keywords acupressure, hyperemesis gravidarum, and PC6 point. Randomized clinical trials on human subjects and studies that measured nausea vomiting index in pregnant woman as outcomes were included. Studies that did not include clinical effects of acupressure were excluded. Results: The following studies on HG (n=4) were discovered. These studies suggested that acupressure might be considered to reduce symptoms of nausea and vomiting in pregnant women. Conclusion: Acupressure at PC6 may reduce nausea and vomiting in pregnant women by influencing gastrointestinal function via nerve stimulation to inhibit cerebral cortex function. Self-care acupressure at the PC6 point may be a therapeutic option to reduce HG during the Covid-19 pandemic.

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