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Ophthalmologica Indonesiana
Published by Perhimpunan Dokter Spesialis Mata Indonesia
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 18 Documents
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Search results for , issue "Vol 42 No 3 (2016): Ophthalmologica Indonesiana" : 18 Documents clear
Grave Ophthalmopathy, Menuju Penatalaksanaan yang Lebih Komperhensif M Sidik
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.90

Abstract

no abstract available
Devastating Lower Eyelid Squamous Cell Carcinoma in Patient with Xeroderma Pigmentosum Novia Rahayu; Neni Anggraini; Rossalyn Sandra Andrisa
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.91

Abstract

Background: Xeroderma pigmentosum (XP), an inherited condition of cellular sensitivity to ultraviolet (UV) radiation, mainly presents as cutaneous and ocular abnormalities, including neoplasia. This report aimed to demonstrate a devastating case of lower eyelid squamous cell carcinoma in XP patient.Case Illustration: Twenty four-year-old female with XP came with white plaque on both cornea. Excisional biopsy revealed a conjunctival intraepithelial neoplasia DD/ carcinoma in situ on right eye, and hyperplastic squamous epithelia on left eye. For nearly two years, she was lost to follow up, and revisited our clinic with a rapid growing, ulcerated, susceptible to bleed, red-yellowish mass, expanding to bulbar and tarsal conjunctiva, about 27 x 15 x 10 mm size, on her lower left eyelid, with restricted ocular movement. Incisional biopsy revealed a well-differentiated squamous cell carcinoma. In 6 weeks time, mass has grown to size 75 x 50 x 20 mm, and already infiltrated to superior eyelid and orbit.Conclusion: The nature of malignancy in XP patient is exceptionally progressive. Thorough education, close monitoring and early treatment is critical to prevent rapid deterioration and minimize possible impairment caused.  Keywords: xeroderma pigmentosum, squamous cell carcinoma, eyelid squamous cell carcinoma, squamous cell carcinoma treatment
Challenge in Diagnosing and Managing Carotid Caverous Fistula in Patient with Intermittent Angle Closure Glaucoma Maria Magdalena; Virna Dwi Oktariana; M Sidik
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.92

Abstract

Background: The purpose of this case report is to present a patient with Carotid Cavernous Fistula (CCF) superimposed angle closure glaucoma and how to manage the IOP and to describe treatment options for CCF. Case Report: A 72-year old female patient was consulted to Glaucoma Division with chief complain the redness of the right eye (RE). She also had blurred vision on both eyes and high IOP of the RE. The IOP of the RE tend to be fluctuated even after laser peripheral iridotomy (LPI) from prior hospital, and was different from the LE, which was stable on anti-glaucoma medication. A careful history taking, clinical examination including visual acuity and visual field defect test, and also ancillary test to confirm the diagnosis were done. The patient was assessed with intermittent angle closure glaucoma (ACG) of both eyes superimposed with carotid-cavernous fistula (CCF) of the RE and planned to undergo trabeculectomy and phacoemulsification surgery from glaucoma division, and also embolization procedure from neuro ophthalmology division. However, the schedule of embolization will be done one year later due to long waiting list at Radiology Departement.Conclusion: This case demonstrates CCF of the RE superimposed intermittent ACG of both eyes. The Clinical manifestation of CCF were subtle, therefore clinical examination and acillary test such as CT angiography were needed to establish the diagnosis and to exclude differential diagnosis. The definitive therapy for CCF is to closure the fistula, but due to long waiting list we have to consider carotid massage as conservative management. In this case carotid massage gave good result in reducing ocular manifestation of CCF.  Keyword: Carotid Cavernous Fistula, Glaucoma, Angle-closure Glaucoma, Carotid Massage
Kebutaan Akibat Kelainan Mitokondria : Gejala, Diagnosis, dan Tata Laksana Suportif Ratna Sitompul
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.94

Abstract

Mitochondria is an important organelle in the cell acting as its powerhouse. Damage in the mitochondria leads to cell death thus it is crucial to organs utilizing plenty of energy such as the eyes. Mitochondrial disease in the eye can be primary or secondary. Primary mitochondrial diseases of the eye include dominant optic atrophy,  leber hereditary optic neuropathy, chronic progressive external ophthalmoplegia,  and retinitis pigmentosa. Secondary mitochondrial eye diseases include diabetic retinopathy, age-macular degeneration and glaucoma. Mitochondrial damage can also trigger growth of ocular neoplasm (retinoblastoma and uveal melanoma) are also part of mitochondrial eye diseases. However, it is still a challenge to diagnose mitochondrial eye diseases. Methods that can be used are genetic sequencing, radiological examinations to look for other syndromic signs, as well as biochemistry and histochemistry assays. Definitive therapy for mitochondrial eye diseases are still under research and to date the management is supportive in the form of food supplementation.  Keywords: primary mitochondrial diseases, secondary mitochondrial disease, mtDNA.ROS, ocular tumour
Visual Field Defect in Pulmonary Tuberculosis Patients with Ethambutol Therapy Agus Nugroho; Devi Azri Wahyuni
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.95

Abstract

Background: Ethambutol (EMB) is important as antimicrobal in the treatment of pulmonary TB which effects ethambutol toxic optic neuropathy (EON). EON can be detected with visual field examination. Research by Vimla Menon stated that toxicity condition of EMB obtained visual field defects by 7.69%. Currently, there is no data on visual field defects in patients with TB treated with (EMB) in Mohammad Hoesin Hospital (RSMH).Methods: This was a cross-sectional observational study with a follow-up studies without controls. The samples of this research was 24 and samples taken consecutive. Visual field examination using the Humphrey Field Analyzer was performed three times: before therapy, 1 month, and 2 months after EMB therapy. Data that can be carried out were analyzed by using SPSS program. Results: Average MD before administration of EMB was -2.36±1.21; average MD after 1 month administration of EMB was -2.35±1.41; and 2 months after was -3.09±1.85. There was a mean change of -0.73±1.43 MD 2 months after EMB administration. Abnormal MD enhancement of 6.52% occured 1 month after EMB administration and 28.26% 2 months after EMB administration. Arcuate visual field defects obtained 9.3% in 2 months after EMB aministration.Conclusion: There was no significant difference in visual field examination on the object before therapy and 1 month after EMB therapy. Examination after obtaining EMB for 2 months, based on the mean deviation of visual field defects, were minimal to moderate; while based on gray scale picture was obtained arcuate visual field defects.  Keywords: ethambutol, EON, visual field defect
The Effect of Zinc Distribution for New TB Patients who Have Ethambutol Therapy Toward Visual Field Defect Neni Daniati; Kusdiantoro Kusdiantoro; Laksmi Wulandari; Nina Mauthia; Lukisiari Agustini
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.96

Abstract

Background: Tuberculosis is an infection disease that is caused by Mycobacterium tuberculosis. Ethambutol therapy for TB patients can cause side effect such as decreased visual acuity, visual field defect, decreased contrast sensitivity, and disturbance of colour detection. Zinc in TB patients has decreased that causes broken cell on retina ganglion and disturbance of mytochondria function. The aim of this study is the effect of zinc supplementation for new TB patients who have ethambutol therapy toward visual field defect.Methods: This study involved 40 new TB patients who have ethambutol therapy which is classified as 20 patients who have ethambutol therapy with zinc supplementation and 20 patients who have ethambutol therapy without zinc supplementation. Each patient underwent a routine examination including visual acuity using Snellen chart which is converted to LogMAR, anterior segment using slit lamp biomicroscope, non-contact tonometry for intraocular pressure examination, posterior segment using direct ophthalmoscope, and Humphrey perimetry for visual field examination which is performed three times on first time when initial patient came, first month, and second month duration.Results: This study showed no correlation between gender with visual field defect (p=0,554), there is no correlation between age with visual field defect (p=0,418), no correlation between smoking behaviour with visual field defect (p=1), no correlation between amount of meals consumption containing Zn with visual field defect (p=0,608), and also no correlation between systematic illness history with visual field defect (p=0,305). The effect of Zn treatment to visual field defect was significant with p=0,0085. Conclusion: Zinc treatment for new TB patients with ethambutol treatment may prevent visual field defect.  Keywords: ethambutol, new TB patients, zinc, visual field defect
Clinical Characteristics and Therapeutic Outcome of Carotid-Cavernous Fistula Ressa Yuneta; M Sidik; Syntia Nusanti; Jacub Pandelaki
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.98

Abstract

Background: Carotid-cavernous fistula (CCF) is an abnormal communication between the carotid arterial system and the cavernous sinus. It can manifest as proptosis, bruit, corkscrew appearance or other signs. The aims of this study were to evaluate the clinical characteristics and result of CCF therapy.Methods: This is a retrospective study which evaluated the clinical characteristic, outcome of therapy and complications after embolization in CCF patient confirmed by digital subtraction angiography (DSA) from January 2012 to December 2014.Results: Twenty-three patients, 16 male and 7 female, were diagnosed as CCF. Mean age was 26±10.5 years old. The most common etiology was trauma (91.3%) with onset ranging from immediately to 17 months after trauma. The frequent ocular manifestations were proptosis, bruit, and conjunctival abnormalities. Other ocular signs were ophthalmoplegia, secondary glaucoma, abnormalities of posterior segment, and decrease of visual acuity. Seventy-eight percent patient was type A CCF. Fifteen patients underwent embolization, 3 patients couldn’t be embolized then treated by manual carotid compression, 5 patients were still waiting for schedule of embolization. Clinical signs of 63% patients were improved in 1 week after embolization. After several months, 2 patients with carotid compression was improved and 1 patient had persistent signs. Complications of embolization include transient sensoric aphasia (1 pasien) and central retinal vein occlusion (2 patients).Conclusion: Clinical characteristics of CCF in this study were not different with previous descriptive studies and most cases showed improvement in clinical signs after therapy.  Keywords: CCF, embolization
The Alteration Visual Field Defect in Ischemic Stroke Patients After Three Months Therapy Frida Lestari; Devi Azri Wahyuni
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.99

Abstract

Background: Ischemic stroke are lack of blood flow to the brain and it could influence the visual field. Approximately more than half of the ischemic stroke patient have visual defect.Objective : Disturbance of blood flow on visual pathway have impact to the visual field defect.  In stroke ischemic patient, recirculation of penumbra at the brain on the third months after onset can  rehabilitate the visual pathway, also it will improve the outcome of visual filed defect. So it could be initial detection for rehabiltation of visual field defect.Methods: This study was intended to compere visual field defect of ischemic stroke patient after three months therapy conducted form September 2014 - February 2015 in Mohammad Hoesin General Hospital Palembang. A total of 12 patients who met the inclusion criteria were recruited by consecutive sampling. All patients were endure based on ophthalmology and visual field examination using Humphrey Field Analyzer twice. First after relieving from the attack of stroke and second after three months therapy. Measurement of standard have to compare the value of MD, VFI, PSD, PD and pattern visual field defect. Results: There were significant difference in value of MD, VFI, PSD  and PD<0,5% for both eyes on stroke ischemic patients after three months therapy. Almost all variable value were increasing to improvement of defect. The most common type of visual field defect  is homonymous hemianopia. Conclusion: There were improvement in visual field defect in patients with stroke ischemic after three months therapy.  Keywords: Ischemic stroke, visual field defect, penumbra, recirculation of brain, Mean Deviation (MD), Visual Field Index (VFI), Pattern Standard Deviasion (PSD), Pattern Deviation (PD)   
Characteristics and Management of Anterior Segment Dysgenesis in Pediatric Ophthalmology Irawati Irfani; Sarah Nurul Ramadanti; Astrid Feinisia Khairani
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.101

Abstract

Background: Anterior segment dysgenesis (ASD) is congenital anomaly caused by malformation of the eyeball during early pregnancy. Intrauterine ASD leads to disorder in maturation of anterior segment of the eye and its complications could interfere the normal visual development. There are several types of ASD and variability of its management. In this report, we described characteristic of ASD including its management in Cicendo Eye Hospital, Bandung. Methods: This is a retrospective descriptive study from medical records of patients with ASD in Cicendo Eye Hospital, Bandung since January 2012 until December 2014. Data were collected based on total sampling with inclusion criteria. All data were analyzed by statistical software. Results: There were 99 patients with range of age 1-day-old until 18-years-old who met the inclusion criteria of this study. Patient of ASD was commonly brought to the hospital at infant age (55.5%), boys in 51.5% patients and mostly came from out of town (70.7%). Thirty-seven percent of their mothers had history of drug consumptions during pregnancy and 30% born prematurity. Seventy percent cases of ASD were bilateral, 80.8% without systemic disease, and congenital glaucoma was the most common type of ASD (30.7%). The most common management was observation in 45.5% cases, followed by combination of surgical and medicamentosa in 30.3% cases. Conclusion: ASD is a congenital condition which has variability in types and management. Early recognition of this condition is necessary to decide the appropriate treatment to assist visual development and rehabilitation.  Keywords: anterior segment dysgenesis, characteristics, management   
Comparison of Corneal Thickness and Endothelial Cell Morphology in Myopic Patients with Daily Wear Hydrogel (Nelfilcon A) and Silicon Hydrogel (Lotrafilcon B) Contact Lenses: A Pilot Study Cut Putri Samira; Tri Rahayu; Aria Kekalih
Majalah Oftalmologi Indonesia Vol 42 No 3 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i3.103

Abstract

Background: To compare corneal thickness and endothelial cell morphology in myopic patients wearing 1 month hydrogel conventional and silicon hydrogel contact lenses in daily wear.Methods: This is a prospective, single blind, randomized study. Seventeen (34 eyes) myopic patients were randomly assigned to receive either nelfilcon A or lotrafilcon B. Central corneal thickness (CCT), coefficient of variation (CV), and percentage of six-sided cell (6A) were examined using specular noncon robo Konan microscope. Changes in CCT, CV, and 6A were evaluated before contact lenses fitting as well as 1 week and 1 month after the treatment. Patients were also evaluated for any subjective side effects and complications during the treatment period. Results: There were 64.7% subjects with history of contact lens wearers and 52.9% of them was hydrogel wearers. After 1 month daily wear of nelfilcon A and lotrafilcon B, no statistically differences changes in CCT (p=0.285; Mann Whitney test), CV (p=0.587; unpaired t-test), and 6A (p=0.353; unpaired t-test). General linear model analysis in follow up evaluation with test of within subject effect revealed decreased in CCT (p=0.001) and CV (p=0.001), also increased in 6A (p=0.022) in all subjects.Conclusion: There were no statistically difference in CCT, CV, and 6A between daily wear of nelfilcon A and lotrafilcon B. Subjects with history of contact lens wearers gained advantages in oxygen availability, which decrease corneal thickness and improve endothelial cell morphology.  Keywords: nelfilcon A, lotrafilcon B, simple myopic, corneal thickness, endothelial cell morphology

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