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Ophthalmologica Indonesiana
Published by Perhimpunan Dokter Spesialis Mata Indonesia
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 13 Documents
 1   2 
Search results for , issue "Vol 49 No 2 (2023): Ophthalmologica Indonesiana" : 13 Documents clear
EFFICACY AND SAFETY OF RHO KINASE INHIBITOR EYEDROPS FOR THE TREATMENT OF OPEN-ANGLE GLAUCOMA AND OCULAR HYPERTENSION: A LITERATURE REVIEW Sahar Salim Saleh Alatas; Astrianda Nadya Suryono
Majalah Oftalmologi Indonesia Vol 49 No 2 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i2.100847

Abstract

Introduction: Reduction of intraocular pressure (IOP) is the only proven method to treat glaucoma. Studies on aqueous humor dynamics have contributed to our understanding of aqueous outflow mechanisms that have led to the discovery of new drugs from Rho Kinase Inhibitors (RKI). Aims: To evaluate the efficacy and safety of RKI for treating open-angle glaucoma (OAG) and ocular hypertension (OHT). Methods: Literature searching was conducted through PubMed, ScienceDirect, Google Scholar, and Springer Link. Search terms included: “Open Angle Glaucoma”, “Ocular Hypertension”, and “Rho Kinase Inhibitors”, which provides for Netarsudil (AR-13530), Ripasudil (K-115)" or any relevant synonym. Validity was assessed using version 2 of the Cochrane risk of bias tool for randomized trials (RoB 2). Efficacy was evaluated by reported mean change IOP from baseline. Safety was assessed by adverse events experienced during the treatment course. Results: Eight randomized clinical trial studies fulfilled our inclusion criteria (four studies using Netarsudil 0.02% and four using FCNL as the primary treatment). IOP reduction from Netarsudil 0.02% was not inferior to Timolol 0.5%. Meanwhile, IOP reduction from FCNL class was statistically superior to its active component alone. The most common adverse events of Netarsudil 0.02% and FCNL were conjunctival hyperemia, cornea verticillate, and conjunctival hemorrhage. FCNL showed additional adverse events of site hyperemia and pain. Conclusion: Netarsudil 0.02% and FCNL can be reliable IOP control medications. The adverse events were tolerable.
EFFECTS OF CATARACT SURGERY ON THE CORNEAL ENDOTHEL Agustian Firmansyah Purnomo; Hidayat Sujuti
Majalah Oftalmologi Indonesia Vol 49 No 2 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i2.100865

Abstract

Introduction: Manual cataract surgery techniques such as SICS and ECCE are still used today but not as many as phacoemulsification. Corneal endothelium can be damaged due to various factors during surgery such as intraoperative manuver, excessive ultrasound power, pressure during irrigation, collision between lens fragments and corneal endothelium, large air bubbles, and increased temperature during surgery. Methods: Journal articles and books in this paper were searched through various available search engines, including using searches through the sites Google Scholar, Medline, Proquest. The search method uses one or a combination of keywords, namely cataract surgery, corneal endothelial damage, corneal endothelium, specular microscope. Articles in this paper are found in English and Indonesian. Results: From several studies it can be concluded that the risk factors that greatly affect the corneal endothelium include age, race, use of contact lenses, surgery, trauma, refractive errors and anatomical abnormalities on the surface of the eyeball. Conclusion: Cataract surgery technique is significantly associated with the incidence of bullous keratopathy because the maneuvers are very prone to injuring the corneal endothel. The average percentage of damage to endothelial cells reaches 15%. This is what underlies the need for further research to find new methods that can protect the corneal endothelium.
QUALITY OF VISION AFTER CATARACT SURGERY: A NEVER-ENDING CHALLENGE FOR OPHTHALMOLOGIST Widya Artini Wiyogo; Johan Hutauruk
Majalah Oftalmologi Indonesia Vol 49 No 2 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i2.100978

Abstract

Page 2 of 2 | Total Record : 13

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