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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 7 Documents
 1 
Search results for , issue " Vol 29, No 04 (1997)" : 7 Documents clear
Borderline, white coat and sustained hypertensia: A comparative study a normotensia in personnels of 18-42 year old at Dr. Sardjito General Hospital, Yogyakarta Suradi, Suradi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A Study of Cross Sectional Survey on 350 subjects from 1216 non physician staffs aged 18-42 at Dr. Sardjito General Hospital was done. There were 51 persons with Borderline Hypertension (15%), consisted of 35 males (68,6%) and 16 females (31,4%), with self monitoring blood pressure at home. The subjects whose average home blood pressure Mean + 1SD and Mean + 2SD, having borderline hypertension had sustained hypertension (SH) and blood pressure while normotensive Mean + 1SD had White Coat Hypertension (WCH). This study found WCH in 25 subjects (49%) and SH 26 subjects (51%). Heart rate of WCH group (83,7-+-5,7) had no significant difference, compared to SH group (86,2 ± 4,1), but was more rapid than normotensive group (74,5 ± 3,6) (p<0.05). There were no significant difference of blood total cholesterol, HDL, LDL, triglyceride between WCH and SH group, but in blood total cholesterol, LDL, triglycerides, were significantly different was compared to normotensive group. A blood HDL of WCH and SH groups had a lower significant different compared to normotensive group (total cholesterol levels 222,4 ± 36,4 vs 217,6 ± 39,7 vs 194,6 ± 33,2), LDL cholesterol (158,2 ± 48,7 vs 156,2 ± 49,1 vs 144,8 ± 33,81, triglycerides (143,6 ± 86,2 vs 146,9 ± 80,2 vs 99,8 ± 51,1). Fasting blood glucose, Insulin and Insulin/glucose ratio in three groups had no significant differences. The conclusions are that total cholesterol, HDL, LDL and triglycerides, and heart rate from WCH group have no significant differences to SH group, but these two groups were significantly different to normotensive group. Fasting blood glucose, insulin, insulin/glucose ratio have no significant difference among the white coat, sustained, and normotensive groups. Key Words: borderline hipertension - white coat hypertension - sustained hypertension - blood chemistry
Wilms tumor associated with Cushing s syndrome - A case report Madarina Julia, Madarina Julia
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Universitas Gadjah Mada

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Abstract

Ectopic ACTH syndrome associated with Wilms tumor is ver
Iron fortification milk supplementation in reducing the incidence of low birth weight. Tonny Sadjimin, Tonny Sadjimin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Universitas Gadjah Mada

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Abstract

The objective of the study was to examine the effectiveness of iron-fortification milk as a supplementation feeding for pregnant women in preventing the incidence of low birth weight. The design of the study was randomized controlled double-masked community trial. The setting were Maternity clinics at the health centers, private clinics, and hospital located in Yogyakarta Municipality, Indonesia. The patients were 138 pregnant women aged 20-30 years, parity of 2 or less, 24-26 gestation weeks, no adverse obstetric history or systemic diseases, signed informed consent. A well-trained field worker at least 24 hours after delivery measured the average weight and length of newborn. The low birth weight was considered to babies who have a birth weight of 2500 g. or less. A logistic regression was used to measure the effect of the intervention to the incidence of low birth weight controlled for several potential confounding variables. The demographic characteristics and laboratory indexes of mothers at the entry were equally distributed between both comparison groups. All 138 mothers were identified during the delivery, but some mothers were refused to have blood drawn at the time of delivery. The incidence of LBW in the study group was 1.4 % and in the control group it was 11.6%, the relative risk of 0.12 (95% CI 0.01 - 0.97). After controlling for potential confounding variable the relative risk become 0.32 (95% CI 0.11 - 0.98).Lactamil, the iron-fortification milks as the supplementation. protein-energy-micronutrient and vitamins to pregnant women are significantly prevent the incidence of low birth weight.Key words: iron - low birth weight - pregnant mother - fortification milk - birth length
Effect of erytropoietin therapy on left ventricle mass and end stage small disease underwent hemodyalisis
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Universitas Gadjah Mada

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Abstract

Cardiovascular disease is the most common cause of death in patients maintained on hemodialysis (HD) of end stage renal disease (ESRD). This study was aimed at evaluating the regression of left ventricular mass (LV mass) and blood pressure among ESRD patients underwent HD. A randomized double-blind placebo controlled clinical trial had been done on 32 patients who underwent HD with acetate. Left ventricular mass was examined with Echocardiography interdialitic time. Fifteen patients (11 males and 4 females) with r-HuEpo therapy (group I) and 16 patients (9 males and 7 females) with placebo (group II) were recruited in the study. The mean age group I was 52.27 ± 14.69 years and Group II: 46.25 ± 9.01 years (95% CI:-2.82 - 14.86; p = 0.117. There was no significant difference in hemoglobin concentration (Hb), hematocrit (Hct), systolic and diastolic blood pressure; LVM at baseline between two groups. After 5 weeks of therapy with r-HuEpo 2000 Unit 2 times/week, the change of mean in hemoglobin concentration in Group I increased: 8.05 ± 1.62 mg/dl to 8.39 ± 2.160 mg/dl and in Group II decreased 7.38 ± 1.2 to 7.13 ± 1.75 mg/dl (p = 0.083,NS), Hct: group I increased 22.54 ± 7.83% to 25.71 ± 6.66%; group II decreased 23.99 ± 4.69 to 21.51 ± 5.29 (p = 0.061,NS) where as systolic blood pressure in Group I increased from 134.615 ± 21.454 mmHg to 140.67 ± 27.12 mmHg, group II increased 144.37 ± 18.24 mmHg to 146,88 ± 26,01 mmHg (p = 0.520, NS); diastolic blood pressure in Group I decreased from 83.076 ± 11.821 mmHg to 79.67 ± 13.43 mmHg, group II 91.25 ± 10.87 mmHg to 90.63 ± 15.69 mmHg (p = 0.046, SI; and the LV mass in Group I reduced from 359.15 ± 107.49 g to 316.32 ± 67.43 g, group II 345.21 ± 89.27 to 340.65 ± 97.84 g (p = 0.434, NS) respectively. In conclusion, after 5 weeks of therapy r-HuEPO tended to reduce left ventricular mass in ESRD patients with maintenance hemodialysis. Left ventricular mass reduction in this patients may be associated with diastolic blood pressure reduction, increase of hemoglobin concentration and increase of hematocrit decrease of end diastolic diameter.Key words: r-HuEPO - left ventricular mass - hemodialysis - echocardiography - end stage renal disease
Polytherapy in the management of epilepsy Samekto Wibowo, Samekto Wibowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Universitas Gadjah Mada

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Abstract

Antiepileptic drugs take a dominant role in the management of epilepsy. Although monotherapy has been recommended, polytherapy sometimes is very difficult to be avoided. This study wanted to remind: what factors should be considered in epilepsy polytherapy. Drug-drug interactions and the risk of side effects might occures. Optimal polytherapy was often achieved with drugs that had different mechanism of action, relatively few side effects, high therapeutic indexes, and limited or no drug interactions. To choose the drug groups, the following factors should also be considered, namely: efficacy, safety, suitability and cost of treatment. In short, polytherapy should be rational.Key words: epilepsy - monotherapy - polytherapy - rational use of drugs - drugs infraction
Number of polymorphonuclear leucocytes in the endocervical discharge smear examination as diagnostic test for chlamydial cervicitis Satiti Retno Pudjiati, Satiti Retno Pudjiati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The chlamydial servicitis is the most prevalent sexually transmitted disease among child-bearing age women and usually asymtomatic in nature, so it is difficult to be diagnosed early and to be eradicated. The laboratory methods for supporting its clinical diagnosis, whether in vitro cultivation or automatic technique, are not only complicated but also expensive. The simplest laboratory testing, especially for primary clinical service with !imitated in laboratory equipment, is achieved by counting the total number of polymorphonuclear leucocytes of endoservical exudate. Unfortunately, the cut off point varied from one country to another. In Indonesia, this cut off point has not determined yet. The purpose of this study was to develop simple and efficient diagnostic test for diagnosing chlamydial cervicitis, by searching the cut off point of a number of polymorphonuclear leucocytes in the endocervical discharge smear examination stained with Gram. The subjects of this study were female sex workers; 44 were from the Clinic of Griya Lentera PKBI Yogyakarta and 36 were from Sanggrahan Resosialisation Yogyakarta. Gynecologic examination, laboratory examination with Gram staining and C. trachomatis antigen detection using Test Pack Chlamydia were done on all subjects. The results indicated that the cut off point of the number of polymorphonuclear leucocyte in diagnosing chlamydial cervicitis is 10 with 60 % sensitivity, 76.67 % specificity, 81 % PPV (positive predictive value) and 53.49 % NPV (negative predictive value).Key words: chlamydial cervicitis - Grams stain - polymorphonuclear leucocyte - test pack chlamydia -female sex workers.
Daytime transmission of filariasis caused by nonperiodic form of Brugia Malaya among Dayak indigenous inhabitants in East Kalimantan. FA Sudjadi, FA Sudjadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

In addition to the previously known of subperiodic and periodic form, the nonperiodic form of B. malayi Lichtenstein was recently reported from East Kalimantan as a new filarial different subspecies. The morphology or natural habitat of filarial parasite was recently described. This paper reports daytime transmission of the disease found in highly endemic area of Dayak, indigenous inhabitants of Krayan area, Long Ikis district, Pasir regency, East Kalimantan. To show such transmission, the microfilaria carrier was followed by daily activities at daytime. When the carrier was at work in the forest, the wild mosquitoes landing and feeding on him were collected, then reared in a laboratory until 14 days. The remains alive of mosquitoes were then morphologically identified and dissected. Infective larvae were recovered from 2 dissected mosquito species, Mansonia bonnae and Mansonia uniformis. Out of 131 alive mosquitoes dissected, 15 (consisting of 10 Ma.bonneae or 13,0% and 5 Ma. uniformis or 11,6%) were found infectious, from which 23 recovered and 11 filarial larvae respectively. Totally, 34 infective B.malayi larvae recovered: 24 larvae from the head and another 10 from the thorax.Key words: Brugia malayi - nonperiodic form - daytime transmission - Mansonia bonnae - Mansonia uniformis

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