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All Journal Jurnal Teknologi Dan Industri Pangan JURNAL GIZI INDONESIA Jurnal Ilmu keperawatan Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Gizi Klinik Indonesia Jurnal Kesehatan Reproduksi Medical Journal of Indonesia Kesmas: Jurnal Kesehatan Masyarakat Nasional UNEJ e-Proceeding Sari Pediatri Paediatrica Indonesiana Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Keperawatan Respati Yogyakarta BKM Public Health and Community Medicine
Madarina Julia
Universitas Gadjah Mada
Agriculture, Biological Sciences & Forestry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Other

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The association of single nucleotide polymorphism (SNP) rs2922126 within ghrelin and growth hormone secretagogue receptor 1a (GHSR1a) gene with insulin resistance in obese female adolescents in Yogyakarta Special Region Madarina Julia, Cut Gina Inggriyani Rina Susilowati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 02 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Previous study reported that among 79 obese female adolescents in Yogyakarta Special Region, 44 (55.7%) of them have insulin resistance. However, no significant differences on dietary habits and physical activity between the obese female who have insulin resistance and thosewho are insulin sensitive were observed. Therefore, it was thought that genetic factors are involved in the occurrence of insulin resistance. Ghrelin and growth hormone secretagogue receptor (GHSR) genes have been associated with the insulin signaling pathway with implicationsin insulin resistance. The study aimed to analyze the association between SNP (single nucleotid polymorphism) rs2922126 in GHSR1a gene with insulin resistance in obese female adolescents in Yogyakarta Special Region. Seventy eight obese female adolescents who were selected in theprevious study were involved in this study. Secondary data including name of subjects, age, body height, body weight, BMI (body mass index), fasting glucose level, fasting insulin level, waist circumference and HOMA-IR index were obtained from previous study. Polymerase Chai Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) methods were used to the genotype analysis of SNP rs2922126. Chi-square test was used to calculate odds ratio on genotype and allele of SNP rs2922126 GHSR1a gene in insulin resistance and insulin sensitive groups. The results showed that A/A genotype individuals in SNP rs2922126 had higher risk to develop insulin resistance, compared to A/T and T/T genotypes individuals (OR: 2.03; 95%CI: 0.54-7.57). However, it was not significantly different (p>0.05). Individuals with A/A genotype and A allele carriers at SNP rs2922126 tended to have a higher value of BMI, fasting glucose level, fasting insulin level, HOMA-IR, and waist circumference compared to other carriers, althoughit was not significant (p>0.05). It can be concluded that SNP rs2922126 in GHSR1a gene is not associated with insulin resistance in obese female adolescents in Yogyakarta Special Region.Keywords: GHSR1a gene - SNP rs2922126 - insulin resistance - female - obese
Hormonal contraception as a risk factor for obesity Sugiharti, Sri; Hadi, Hamam; Julia, Madarina
Medical Journal of Indonesia Vol 14, No 3 (2005): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.764 KB) | DOI: 10.13181/mji.v14i3.191

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Hormonal contraception is related to change in the metabolism of some nutrients that may lead to an increase in body weight. The aims of this study is to assess the risk of obesity in hormonal contraceptive users in the District of Kulon Progo, Jogjakarta, Indonesia. A cross sectional study was used to determine the prevalence of obesity among users of contraception. A systematic cluster random sampling, using villages as clusters, was used to choose 647 users of contraception in Kulon Progo.  A hundred and two obese cases and 102 control, matched-for-age and socioeconomic status, controls were included in the case control study used to evaluate the risk of obesity among users of hormonal contraception. The prevalence of obesity among users of contraception in Kulon Progo was 15.9%. Users of hormonal contraception has a increased risk for obesity, OR: 9.4 (95% CI: 1.1 – 81.5). Users of combination pills faced the highest risk, followed by users of injected progesterone depot, while the risk in implant users was the same as that in users of non-hormonal contraception. The risk of obesity was significantly higher after 7 years of hormonal contraception use. The risk of obesity was neither related to energy intake nor expenditure. The increased risk of obesity in users of hormonal contraception was still significant after controlling for age, parity, initial weight, socioeconomic status, energy intake and expenditure, and parental obesity. We conclude that the risk of obesity is higher in users of hormonal contraception compared to the non-hormonal ones. Users of combination pills face the highest risk of obesity. (Med J Indones 2005; 14: 163-8)Keywords: hormonal contraception, family planning, obesity, case control study
Body mass index and waist-to-height ratio cut-offs as predictors of high blood pressure in adolescents Febriana, Kurnia; Nurani, Neti; Julia, Madarina
Medical Journal of Indonesia Vol 24, No 1 (2015): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2272.352 KB) | DOI: 10.13181/mji.v24i1.1200

Abstract

Background: Obesity is associated with increased risk for high blood pressure (BP). Although a routine BP measurement is indicated for all children visiting pediatric practice, recognition of children particularly at risk may save times. The aim of this study was to assess the cut-off point for body mass index (BMI) and waist-to-height ratio (WHtR) to predict high BP in adolescents. Methods: We conducted a cross-sectional study on 928 children aged 11 to 16 years in Yogyakarta. BP were measured using standard technique described by The Fourth Report on The Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents. BMI was adjusted for age and sex using the WHO 2007 growth reference. WHtR was ratio of waist circumference related to height in centimeters. Receiver operating characteristic (ROC) curves were used to estimate the best cut-offs. Results: The best cut-off point for BMI-for-age Z-score (BMIZ) to predict high BP was 0.51 with sensitivity and specificity of 82% (95% CI = 78-86) and 76% (95% CI = 67-78) for systolic BP and sensitivity and specificity of 82% (95% CI = 78-86) and 72% (95% CI = 68-76) for diastolic BP. The best cut-off point for WHtR was 0.45, with sensitivity of 76% (95% CI = 67-78) and specificity of 74% (95% CI = 71-79) for systolic BP and sensitivity of 76% (95% CI = 72-80) and specificity of 70% (95% CI = 61-75) for diastolic BP.Conclusion: BMIZ of 0.51 and WHtR of 0.45 are the best cut-off point to predict high BP in adolescents.
Diabetes mellitus type 1 in congenital rubella syndrome: a case report E.S. Herini, Carina Lisa Madarina Julia
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 40, No 04 (2008)
Publisher : Universitas Gadjah Mada

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Corina Lisa, Madarina Julia, E.S. Herini . Diabetes Mellitus Type 7 in Congenital Rubella SyndromeDiabetes mellitus type 1 has been reported as a very rare delayed manifestation of congenital rubella syndrome. We reported a confirmed case of congenital rubella syndrome that developed diabetes mellitus at the age of seven years. The girl had been complaining of diabetes symptoms since six months before admission, but had been misdiagnosed. The patient finally came with symptoms of diabetic ketoacidosis, a life threatening complication of diabetes mellitus. Diabetes mellitus type 1 as a delayed manifestation of congenital rubella syndrome has to be kept in mind to prevent missing the diagnosis.Key words: rubella infection - congenital rubella syndrome - diabetes mellitus type 1ABSTRAKCorina Lisa, Madarina Julia, E.S. Herini - Diabetes Mellitus Tipe 7 pada Sindroma Rubella KongenitalDiabetes melitus adalah salah satu manifestasi lambat sindrom rubella kongenital yang jarang, tetapi perlu diwaspadai. Kami melaporkan satu kasus sindrom rubela kongenital yang mengalami diabetes melitus tipe 1 pad a usia 7 tahun. Meskipun gejala diabetes telah dikeluhkan sejak enam bulan sebelum masuk rumah sakit, penyakit diabetes tetap tidak terdiagnosis. Penderita akhirnya datang dengan gejala dan tanda ketosidosis diabetikum, suatu komplikasi diabetes mellitus yang mengancam jiwa. Manifestasi lambat sindrom rubella yang berupa diabetes mellitus tipe I harus diwaspadai untuk mencegah tidak terdiagnosanya penyakit tersebut.
Wilms tumor associated with Cushing s syndrome - A case report Madarina Julia, Madarina Julia
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Universitas Gadjah Mada

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Abstract

Ectopic ACTH syndrome associated with Wilms tumor is ver
Comparison of daily vs. weekly single-dose ferrous sulphate treatment in female junior high students with iron deficiency anemia Madarina Julia, Dedy Afandi, Sri Mulatsih,
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 01 (2009)
Publisher : Universitas Gadjah Mada

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Background: Complianc~ of daily treatment of iron deficiency anemia in children is still low. The compliance will be increased if the iron supplementation is given weekly. Previous study showed that there was no significant difference in the increase in hemoglobin level between daily and weekly treatment in prepubertal children. Objective: To study the difference in the increase in hemoglobin and serum ferritin levels between daily and weekly sirigle-dose treatment of ferrous sulphate in female junior high school students with iron deficiency anemia after menarche. Methods: This was a quasi-experimental study recruiting 179 and 174 anemic female students in the weekly and daily group, respectively. They receive weekly or daily single-dose of ferrous sulphate capsules. Hemoglobin levels were measured before and after the 12 weeks treatment, while serum ferritin levels were measured before and after in a subset of the study subjects. Result: Mean:t SD levels of hemoglobin before and after iron supplementation were 11.18:1: 0.51 and 12.79:t0.63 g/dl (p=0.001) in the weekly group, and 11.17:1:0.61 and 12.68:1:0.57 g/dl (p=0.001) in the daily group. Mean:l: SD levels of ferritin before and after iron supplementation were 6.95:1: 1.85 and 41.5:1:33.93 ng/ml (p=0.001) in the weekly group, and 6.61 :1:2.17 and 40.7:1:22.73 ng/ml (p=0.001) in the daily group. The prevalence of anemia after supplementation is similar in both groups, i.e. 6.7% in the weekly group and 8.0% in the daily group (p = 0.631. There were no significance difference in the occurrence of side effects of diarrhea and nausea in both groups (p>0.05). Conclusion: This study concluded that daily vs. weekly ferrous sulphate supplementation did not result in significantly different level of both hemoglobin and serum ferritin after treatment. The difference in the occurrence of side effects was also not statistically significant. Key words: anemia iron deficiency - hemoglobin level - serum ferritin level - ferrous sulphate
Hubungan Pola Asuh Keluarga dengan Kejadian Kurang Energi Protein Anak Balita Akhmadi, Akhmadi; Hadi, Hamam; Julia, Madarina
Jurnal Ilmu Keperawatan Vol 2, No 1 (2007)
Publisher : School of Nursing Faculty of Medicine Universitas Gadjah Mada

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Please refer to the file
Konsumsi rokok dan asupan zat gizi balita pada rumah tangga miskin Irwanti, Winda; Julia, Madarina; Prabandari, Yayi Suryo
Jurnal Gizi Klinik Indonesia Vol 9, No 3 (2013): Januari
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.915 KB) | DOI: 10.22146/ijcn.15445

Abstract

Background: Eradication of poverty and starvation is still an agenda of Millennium Development Goals (MDGs) 2015 due to the serious impact of poverty and starvation to human beings. Poverty and starvation are worsened by smoking habit of the Indonesian population. Expenditures used for cigarettes may bring bad impact to the health of toddlers, including lack of nutrient intake. However, until today it is not yet precisely known how much lack of nutrient intake in toddlers caused by cigarette consumption. Objective: To identify difference in nutrient intake of energy and protein of toddlers based on the amount of cigarettes consumed in poor household at Yogyakarta Municipality.Method: The study used cross sectional design. Subject consisted of 86 toddlers of two-five years living in poor household at Yogyakarta Municipality. Cigarette consumption, mother of toddlers and all members of the family were obtained from interview. Method to assess intake was multiple 24 hours food recall within four days, whereas interview was used to assess cigarette consumption. Statistical analysis was performed by using Two Sample Independent t-test, Mann-Whitney U-test, regression, and Chi-Square.Results: As much as 77.9% of poor household had at least one smoker. There was no significant difference in intake of energy and protein of toddlers living with smokers and non smokers, though percentage of expenditure for food was significantly lower in the household with smokers. This might be due to high consumption of food with high energy density at affordable price and protein at low price. Snacks were the third most consumed by toddlers and 40% of animal protein consumed were eggs.Conclusion: There was no significant difference in intake of energy and protein of toddlers living in the poor household with smokers and those living with non smokers, but percentage of expenditure for food significantly lower in household with smokers. 
Pengaruh status gizi ibu menyusui terhadap eksklusivitas pemberian ASI dan pertumbuhan bayi di RSUD Prof. Dr. WZ. Johannes Kupang Soi, Beatrix; Julia, Madarina; Budiningsari, R Dwi
Jurnal Gizi Klinik Indonesia Vol 2, No 3 (2006): Maret
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.404 KB) | DOI: 10.22146/ijcn.17431

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Background : Numerous research have been made to find out contributive factors of the exclusive breastfeeding.Objective: The objective of this study was to find out whether mothers’ nutritional status had any influence on the exclusivity of breastfeeding and  on the growth of their babies up to 4 months.Methods: This observational study was carried out with a prospective cohort design and lasted from November 2004 to May 2005. The subjects were 80 pairs of mother and baby treated at the Obstetric and Gynecology Unit (UPF) of Local Public Hospital (RSUD) Prof. Dr. W.Z. Johannes at Kupang – NTT. The subjects were divided into two groups namely Undernutrition status group marked by <23,5 cm mid arm-circumference, and control group comprised 46 mothers of well- nutrition  status who had bigger mid arm-circumference >23,5 cm. Observed babies were those of normal or spontaneous delivery, non twin with >2500 g birth weight. Follow up observations were made at family home and the data on breastfeeding characteristics were collected by interview, babies weight were measured by Secca baby scale with 0,01 kg level of accuracy mid arm-circumference was measured by means of LILA tape, and body length was measured using length-board. Tools measure with 0,1 cm level of accuracy. Some statistical tests were used namely Chi-Square; student’s t-test; and while Kaplan Meier log-rank test as needed.Results: More than 50% of under-nutrition mothers were under 25 years old. Chi-Square test shows that significant difference between mother’s age was (p=0,04). More than 50% of the KEK group gave birth for the first time or ‘primipara’ (p=0,25). Kaplan Meier analysis showed that  there was no difference between survival median of breastfeeding be- tween the both group (p=0,53). t-test showed that there were significant differences of the babies body weight of the both KEK and non KEK mothers, namely pd”0,01, p=0.01, and p=0.03 in the first, second, third, and the fourth month respectively. In terms of the average babies body length, the t-test also showed significant differences between both groups with p=0.02 and p=0.01 in the third and the fourth month respectively.Conclusion: I can be concluded that mother’ nutrition status did not have any influence on the exclusivity of breastfeeding, however, it did significantly influence babies growth from 0- 4 month.
Kondisi lingkungan fisik dan lama waktu bermain di luar rumah dengan kegemukan pada anak prasekolah Agustina, Ika; Gunawan, I Made Alit; Julia, Madarina
Jurnal Gizi Klinik Indonesia Vol 12, No 4 (2016): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

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Background: The prevalence of childhood obesity in Yogyakarta Municipality has increased in recent years. The built environment of which are not designed properly may limit the time for children's outdoor activity.Objective: This study tried to investigate the links between parents perceptions of their built environment with outdoor playing time and obesity among preschool children in Yogyakarta Municipality.Method: This is a case-control study. Cases were identified as obese preschoolers (Z score based on W / H> 2 SD) and controls were children who were not obese (Z score based on W / H ≤ 2 SD) and matched by sex and age. Data were collected in the Yogyakarta Municipality. Samples were selected using multistage sampling method. The sample of cases and controls were 101 people (1: 1), respectively. conditional logistic regression statistical tests were performed to identify the risk factors for preschool obesity.Results: Children who did not play outdoors enough time were at higher risk of becoming obese (OR = 2,27, CI (1,14-4,62)); Built environment seems to be a modifier for outdoor playing time that will impact the odds of obesity among preschool children. Conclusion: Preschool children who played outdoor less than 2 hours had a higher risk of becoming obese. Outdoor playing time was associated with built environment.
Co-Authors A.A. Ketut Agung Cahyawan W Achmad Surjono Adhila Fayasari Agustini Utari Ahmad Husain Asdie Ahmad Husain Asdie Ahmad Husain Asdie Almira Sitasari Aman B Pulungan Andi Imam Arundhana Ari Tri Astuti, Ari Tri Arief Priambodo Astuti, Lucia Mawarti Dwi Attika A. Andarie Basuki, Siswanto Cerdasari, Carissa Dewi Astiti Diadra Annisa Dio Biade Djaswadi Dasuki Djaswadi Dasuki Djauhar Ismail Ekawaty L. Haksari Emy Huriyati Endang Baliarti Endy P. Prawirohartono Endy Paryanto Prawirohartono, Endy Paryanto Eni Harmayani Esti Nurwanti Farida Wahyu Ningtyas Farida Wahyu Ningtyias, Farida Wahyu Fitri Haryanti Frida Soesanti Gunawan, I Made Alit H. A. Delemarre-van de Waal HA Delemarrevan de Waal Hamam Hadi Hamam Hadi Handayani Handayani Harry Freitag Luglio Muhammad Helmyati, Siti Hendratini, Julita Hizni, Alina I Made Alit Gunawan I Wayan Bikin ika agustina Indria Laksmi Gamayanti Indria Laksmi Gamayanti Irma Yunawati Joko Susilo Jufrrie, Muhammad Junaidi Junaidi Jurianto Gambir Kandarina, Bernadette Josephine Istiti Khaerul Anwar Krisnanto, Paulinus Deny Kunayarti, Wahyuni Kurnia Febriana Laksono Trisnantoro Lamana, Aspia Legawati Legawati, Legawati Lely Lusmilasari, Lely Lisma Evareny, Mohammad Hakimi, Retna Siwi Padmawati M M van Weissenburch M. M. van Weissenbruch Muchtar, Mohammad Mursyid, Abidillah Neti Nurani Neti Nurani Niken Pritayati Nina Lestari Noormanto Noormanto, Noormanto Nur Afia Amin Nurliyani Nurul Hadi, Nurul Pangesti, Neni Purnama, Ni Luh Agustini Putra, Irwansyah R. Dwi Budiningsari Rahayu, Endah Sri Rahmawati, Rahmawati Ramadhaniah, Ramadhaniah Ramli, Nurlaili Retno Sutomo Rianti Puji Lestari Rina Susilowati Riris Andono Ahmad Roni Naning Ruqoyatul Himah S. Yudha Patria Santi Gunarwati Setya Wandita Shelly Puspa Anggraini Shinta Prawitasari Shoim, Mohammad Siti Nurfadilah H Slamet Rohaedi, Slamet Soeroyo Machfudz, Soeroyo Soi, Beatrix Sri Mulyati Sri Sugiharti Sri Wahyuni Subardjo, Yovita Puri Sulistyaningrum, Elisa Sunartini Sunartini, Sunartini Tarigan, Noviani Titih Huriah Titih Huriah Toto Sudargo Tunjung Wibowo Tuti Nuraini Winda Irwanti, Winda Winda Nurmayani M Yayah Lakoro Yayi Suryo Prabandari Zulfayeni, Zulfayeni