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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 7 Documents
Search results for , issue " Vol 30, No 02 (1998)" : 7 Documents clear
The effect of ciprofloxacin on the susceptibility of pseudomonas aeruginosa to tetracycline Ning Rintiswati, Ning Rintiswati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 02 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The effect of ciprofloxacin on the susceptibility of Pseudomonas aeruginosa to tetracycline was evaluated. This study was based on the fact that most bacterial resistance to an antibiotics is under control of genes located on plasmids. Treatment with ciprofloxacin at subminimal inhibitory concentration possibly alter the supercoiled to the relaxed form, so that the plasmids could not be expressed, whereas at the same time the bacterial chromosome would not be affected by the treatment. The aim of this study was to search for possible increase of tetracycline susceptibility of P.aeruginosa, under the influence of ciprofloxacin. Thirty two isolates of P.aeruginosa were used In the experiment. Minimal inhibitory concentration (MIC) of ciprofloxacin for an individual isolate was determined by a standard broth dilution method. Fresh cultures with the density of 106CFU/m1 were added Into a serial tubes containing various concentrations of tetracycline. Ciprofloxacin at sub MICs was then added into these cultures. The same cultures containing only tetracycline were used for controls. The results showed that the decrease of MIC of tetracycline was observed in 31 (96.87%) isolates of P.aeruginosa, and 34.37% changed their resistance stated. It was concluded that ciprofloxacin increased tetracycline susceptibility of P.aeruginosa.Key words : ciprofloxacin - plasmid - antibiotic susceptibility - P. aeruginosa-tetracycline
Relationship between explanations of cause of mental illness and the strengthening of being religious Soewadi, Soewadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 02 (1998)
Publisher : Universitas Gadjah Mada

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Abstract

The misconception of disease and health of people is influenced by belief In supernatural spirits or magic. This study was designed to contribute to our understanding of the relationship between perceived cause of illness and religious strength. A study was carried out In the Facuity of Medicine Gadjah Mada University, Yogyakarta, Indonesia, among first year students. Data were analyzed using Chi square technique (Mantel Haenszel) and contingency correlation coefficient. The results of the study showed that there was no significant difference between groups of subjects who believed and did not believe in supernatural cause of mental illness according to the religious strength (X2 = 0.88; p>0.05). The results Identified some of the subjects (52.9%) believed in supernatural cause of mental illness and there was also a correlation between such beliefs and the religious strength (C.0 = - 0.13). It was concluded that there was no relationship between perceived cause of mental Illness and the religious strength.Key words : mental Illness - religious - anxiety - mysticism - believe
The effect of Aloe vela on fibroblast cell growth Sri Herwlyantl, Sri Herwlyantl
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 02 (1998)
Publisher : Universitas Gadjah Mada

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Abstract

The study was designed to Investigate the effect of Aloe vera on fibroblast cell growth in vitro. The fibroblast cell culture in a microplate was prepared from twelve day old chicken embryos. Each well was added with 0.3 cc fibroblast suspension. Various concentrations, i.e: 0.010 g/m1; 0.015 g/ml and 0.020 g/ml of Aloe vera were then added into the well, incubated afterwards for 24, 48 and 72 hours at 37° C and were examined under a phase contrast microscope. The results showed that the density and number of fibroblast were Increased, proportionally to the concentration of Aloe vera. The control wells were added with fibroblast only suspension. In the control groups, however, there was only a slight increased and density of cells occured. In conclusion, Aloe vera could stimulate the fibroblast growth.Keywords: Aloe vera - fibroblast - cell culture - chicken embryo - growth factor
Filariasis caused by nonperiodic form of Brugia ma/ayi among transmigrants in East Kalimantan. FA Sudjadi, FA Sudjadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 02 (1998)
Publisher : Universitas Gadjah Mada

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Abstract

A new subspecies of sylvanic or human filarial worm, i.e. nonperiodic form of Brugia malayi Lichtenstein, was recently discovered in East Kalimantan, which was highly prevalent among Dayak indigenous people living in the deep forest. This paper reports the filarial infections among transmigrants coming from Java who have been resettled for about 30 years in the UPT (unit of transmigration resettlement) of Petung, Penajam district, Pasir regency. Higher filarial infections were recorded among transmigrants living in hilly parts of the UPT, such as those found in Gunungrejo subvillage, with a micro-filarial rate of 6.3%, clinical rate of 8,1% or filariasis rate of 12,9%, out of 520 people examined. In more swampy areas, such as those found in Kedungrejo subvillage, the parasite Infection rate was much lower, and was recorded only 3,1%, out of 578 people examined. The result of blood or clinical examinations carried out in this research also indicated that male and older Inhabitants or transmigrants who have stayed longer in Kalimantan have a higher risk of Infection.Key words: transmigrants - Brugia malayi - nonperiodic form - sylvanic filaria - mansonia
Effect of water extract of meniran (Phyllanthus niruri L.) on toxic effect of aflatoxin B1 in liver of rats (Rattus norvegicus) (in Vivo) Sri Suharmi, Sri Suharmi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 02 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Phyllanthus niruri L. (meniran) is well known and can be used for traditional treatment of various diseases such as jaundice, diarrhea, and infection of tractus urinarius. The studies showed that the extract of Phyllanthus nirurl L. could be used as antihepatotoxics. This study was designed to investigate the effect of 10%, 20%. and 30% water-extract of Phyllanthus niruri L. herbs on the rats liver treated with 15 ug aflatoxin 131 (AFB1) In 0,2 ml propylene glycol, orally by tube, everyday for 16 and 24 weeks. Employing the analysis variance, significant effect was observed in serum glutamate-pyruvate transaminase (SGPT) and livers cytosol glutamate-pyruvate transaminase (GPT), but was not significant in livers cytosol glutathione S-transferase (GST). However among inter group analysis, significant decrease in SGPT and livers cytosol GPT observe only group treated with 20% water-extract of Phyllanthus niruri L. herbs and AFB1 compared to group treated with AFB1  (p<0,05). The study also demonstrated that 20% water-extract Phyllanthus niruri L. herbs could prevent metaplasia, hyperplasia, and proliferation of the bile duct epithellial cells and altered foci in the hepatocytes were caused by AFB1.Keyword : aflatoxin 131 - glutamate-pyruvate transaminase - glutathion S-transferase - Phyllanthus niruri L. - rats liver
Comparison of tracheal intubation conditions after 45 seconds, 60 seconds rocuronium and succinylcholine treatments in elective surgery Muhdar Abubakar, Muhdar Abubakar
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 02 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The tracheal intubating conditions of rocuronium and succinylcholine under balanced anasthesik with midazolam, fentanyl, penthotal, nitrous oxide, oxigen and halothane were studied in 38 patients undergoing elective surgery. Patients were given either 0.6 mg/kg rocuronium or 1 mg/kg succinylcholine intravenously. forty five seconds after the administralon of rocuronium, or 60 seconds after the administration of rocuronium or succinylcholine, the trachea was intubated and the intubating conditions were scored by blinded assessor. Intubating conditions were the same between the rocuronium and succinylcholine group. (p = 0.18) The hemodynamic effect were the same among the three groups. The result showed that all patients with 0.6 mg/kg rocuronium could be Intubated within 45 seconds as well as 60 seconds; however, those intubated within 60 seconds were similar to those with 1 mg/kg sucdnylcholin.Key words: intubating conditions - rocuronium - succinylcholine - tracheal intubation - hemodynamic effect
Vogt-Koyanagi-Harada Syndrome: A case report Suhardjo, Suhardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 02 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The Vogt-Koyanagl-Harada Syndrome is characterized by bilateral panuveitis and exudative retinal detachments, in association with cutaneous and neurosensory manifestations. This syndrome is seen most commonly in darker pigmented races, such as Orientals, Hispanics, American Indians, and blacks. It affects both sexes, although it appears to be a distinct female predominance. Most patients are between 20 to 50 years of age, but children and older adults also may be affected. A patient with some clinical symptoms of Vogt-Koyanagi-Harada (VKH) syndrome was reported. This patient had chronic bilateral iridocyclitis, posterior uveitis, exudative retinal detachment, cataracts related to cutaneous manifestations. This patient well responded on ophthalmologic manifestations by corticosteroid treatment but the other signs of VKH syndrome were still developing after 4 months period. The therapy for VKH syndrome was the high doses of systemic corticosterolds, and, with the severity of the anterior uveitis, topical corticosteroid was administrated frequently. A short-acting corticosteroid such as prednisone, in the range of 100-120 mg/day was given, based on the severity of the Inflammation. Some patients might require the addition of cytotoxic agents or cyclosporine.Key words : Vogt-Kayanagi-Harada syndrome - bilateral iridocyclitis - exudative retinal detachment - cutaneous manifestations.

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