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BALI MEDICAL JOURNAL (BMJ)
Published by Universitas Udayana
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Bali Medical Journal (BMJ), P-ISSN 2089-1180, E-ISSN 2302-2914 is an international and peer-reviewed journal published quarterly in print and online by Sanglah General Hospital in collaboration to Indonesian Physician Forum and Indonesian College of Surgeon, Bali-Indonesia which was founded in 2011. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship, and to encourage a vigorous dialogue between medical scholars and practitioners. The Journal welcomes contributions which promote the exchange of ideas and rational discourse between practicing educators and medical researchers all over the world.
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Articles 14 Documents
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Search results for , issue "Vol 5 No 1 (2016)" : 14 Documents clear
SUSCEPTIBILITY OF RIFAMPICIN-ISONIAZID RESISTANT MYCOBACTERIUM TUBERCULOSIS ISOLATES AGAINST LEVOFLOXACIN Kurniawan, Alvin Hartanto; Mertaniasih, Ni Made; Soedarsono, S.
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Tuberculosis (TB) is a high burden disease in Indonesia with multidrug-resistant (MDR) TB incidence started to increase. Treatment success of MDR-TB globally was low in number than it was targeted which was especially caused by fluoroquinolone resistance. One of the fluoroquinolone is levofloxacin, an antibiotic that has been widely used irrationally as antimicrobial treatment. Therefore, this study investigated the sensitivity and MBC of MDR Mycobacterium tuberculosis isolates against Levofloxacin. Method: The susceptibility test for MDR -Mycobacterium tuberculosis on levofloxacin by standard method with levofloxacin were on concentrations 0,5 ?g/ml, 1 ?g/ml, and 2 ?g/ml. Sample of 8 strains MDR-Mycobacterium tuberculosis were cultured with each concentrations on Middlebrook 7H9 for 1 week incubation. Next, each of the incubated concentration was subcultured on solid media Middlebrook 7H10 for 3 weeks incubation. Colonized agar plates after 3 weeks incubation were confirmed with acid-fast stain. Results: On MB 7H10 with levofloxacin concentration 2 ?g/ml showed bactericidal effect 100% by no MDR Mycobacterium tuberculosis colony grew (0/8) while the MB 7H10 with levofloxacin concentration 1 ?g/ml and 0,5 ?g/ml showed the bactericidal effect 37,5% and 25% respectively. The colonized agar plate implied that the MDR Mycobacterium tuberculosis with levofloxacin concentration 1 ?g/ml (5/8) and 0,5 ?g/ml (6/8) grew well. Conclusion: Levofloxacin concentration 2 ?g/ml was susceptible on MDR Mycobacterium tuberculosis. The concentration 2 ?g/ml of levofloxacin could be considered as MBC.
Stereotactic Radiosurgery for Classical Trigeminal Neuralgia Kodrat, Henry; Novirianthy, Rima
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Trigeminal neuralgia is a debilitating pain syndrome with a distinct symptom mainly excruciating facial pain that tends to come and go unpredictably in sudden shock-like attacks. Medical management remains the primary treatment for classical trigeminal neuralgia. When medical therapy failed, surgery with microvascular decompression can be performed. Radiosurgery can be offered for classical trigeminal neuralgia patients who are not surgical candidate or surgery refusal and they should not in acute pain condition. Radiosurgery is widely used because of good therapeutic result and low complication rate. Weakness of this technique is a latency period, which is time required for pain relief. It usually ranges from 1 to 2 months. This review enlightens the important role of radiosurgery in the treatment of classical trigeminal neuralgia.
A Young Male with Spontaneous Ruptured Cerebral Arteriovenous Malformation (Case Report) Santos, Vitorino M.; Flores, Leandro P.; Barros, Isabella A.; Faria, Priscilla S.; Lamounier, Carolina P.; Casasanta, Renata A.
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Cerebral arteriovenous malformation (AVM) is considered a congenital condition characterized by arterial-venous connections in the absence of intermediate capillaries with circulatory and functional changes, inclusive on the cerebrospinal fluid (CSF) dynamics. Case: A previously healthy young man with abrupt onset of intense headache followed by incoercible vomiting and generalized tonic-clonic seizures. On admission, he was in Glasgow scale IV with respiratory gasping, signs of decerebration and anisocoric mydriasis, and right paresis. Computed tomography showed left intraparenchymal hematoma and intraventricular blood. The abnormal vessels and blood clots were removed by neurosurgery. In early postoperative phase a large cerebrospinal fluid leak developed, and was aspirated and further controlled. The patient had respiratory complications, including pulmonary infection by Pseudomonas. Conclusions: After longstanding hospitalization, he was referred to other medical institution and home care.
CHARACTERISTICS OF HYPOSPADIAS CASES IN SANGLAH GENERAL HOSPITAL, BALI-INDONESIA: A DESCRIPTIVE STUDY Duarsa, Gede Wirya Kusuma; Nugroho, Teguh Dwi
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Hypospadias is one of the most common congenital anomalies. The purpose of this study is to assess the characteristics of hypospadias patients in Sanglah General Hospital, and the type of hypospadias repair and the outcome. Methods: The data is collected retrospectively from the hypospadias patients’ medical records who undergone a hypospadias repair between January 2009 to April 2012. The data is analyzed descriptively to describe the characteristics of hypospadias patients, the procedures taken, and the outcomes. Results: From 42 patients, type of hypospadias are 33.3% (n=14) penoscrotal; 21.4% (n=9) scrotal; 14.3% (n=6) corona; 26.2% (n=11) penile; 2.4% (n=1) subcoronal; 2.4% (n=1) and perineal. Chordee was present in 67.9% cases (n=36), and cryptorchidism present in 3.7 % case (n=2). The urethroplasty techniques applied: TIP 55.6% (n=15); Duckett Preputial Island Flap 14.8% (n=4); MAGPI 14.8% (n=4); 14.8% (n=4) two stages urethroplasty. Complication rate of Duckett is 50% (n=2) urethra cutaneous fistula; MAGPI 25% (n=1) meatal stenosis; TIP 20% (n=3), 2 urethrocutaneous fistula, 1 urethral stricture; 2 stages urethroplasty 0% (n=0). Conclusion: The findings suggest a different frequency of the proportion of the type of hypospadias in this study when compare to the readily available literature. The age of the patients undergone hipospadias repair was higher compare to other studies. TIP technique was the most preferred in Sanglah Hospital.
The Effects of Platelet-Rich-Plasma (PRP) Injection On Ligament Injury Kloping, Yudhistira P.; Desnantyo, Andre T.; Rehatta, Nancy M.
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Soft tissue injuries are becoming a problem especially among active people and athletes, thus doctors are focusing on PRP injection however variety of study results are making the beneficial effects of PRP towards soft tissue healing unclear. The purpose of this study is to clarify the effects of PRP injection on the healing aspect of a ligament injury. Methods: The experimental study used European rabbit (Oryctolagus cuniculus), which was divided into the control and treated group. The 22 samples, ankle ligaments were injured. The treated group was injected with 4 ml PRP taken autologously. On the 2nd day the samples were examined for hematoma. 4 samples from each group were also examined histopathologically. On the 2nd week, the ligament thickness of the remaining samples from each group was examined ultrasonographically. Results: The clinical result showed lower presence of hematoma on the group injected with PRP compared to the control group. The Capillary dilation was less on the treated group compared to the control group. The Inflammatory cells were less on the treated group compared to the control group. The Fibroblasts Cells was less on the treated group compared to the control group. The fibrocytes was more abundant on the treated group compared to the control group. The average of Ligament Thickness was thicker on the treated group compared to the control group. Conclusion: The Injection of PRP is beneficial to a ligament injury based on its effect on enhancing healing on the inflammation, regeneration, and remodeling phases.
Dynamics of Human Mesenchymal Stem Cells, M1 Microglia/Macrophage, and Fractalkine in Ischemic Stroke Patients Herminawati, Lucia; Wijaya, Andi; Arief, Mansyur; As’ad, Suryani
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: About 85% of strokes are ischemic strokes, caused by occlusion of cerebral artery that induced brain inflammation. A deep understanding of ischemic stroke mechanism will lead to better neurorestorative treatment. Objective: This study investigates the dynamics of human mesenchymal stem cells, fractalkine, and M1 microglia/macrophage in ischemic stroke patients. Results: We found the same fractalkine levels and M1 microglia/macrophage cells on patients with stroke onset 0 to 14 days, then decrease until 30 days of stroke onset. MSCs was increase 7 days after stroke onset, peaked by 14 days, then decreased until 30 days after stroke ischemic onset. Conclusions: This study found an interaction between microglia/macrophage, fractalkine, and MSCs on ischemic stroke patients, so therapeutic strategy could be developed.
The Relationship between Body Image Coping Strategy and Eating Disorders among Iranian Adolescent Girls Farid, Malihe; Kamrani, Mahnaz Akbari
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Due to physical and psychological changes during puberty, most common problem of young people is body image defined as degree of size, shape and general appearance. Wrong perception of body image and dissatisfaction with body image in people can lead to eating disorders and stress. Peace of mind is in fact a mental mechanism that people use it to reduce physical and emotional strains coping with stressful situations. The aim of this study was to determine the type of coping strategy of adolescent girls and its relationship with their eating disorders. Methods: This is study is a cross-sectional study in which 573 female adolescent of Karaj participated. Two-Stage Random Sampling was used in this study. In this study, to assess people who are at risk of eating disorder, the nutritional approach assessment questionnaire of EAT-26 was used, while Strategy Inventory Body Image Coping- BICSI questionnaire was used to determine the type of coping strategy. Results: In this study, the mean age of participants was 16.6 (±1/62) (19- 14 years). In this study, 23.7% of participants had an eating disorder. Mental image of an individual of his body had significant correlation with eating disorder (P= 0.000). Kruskal-Wallis test showed a significant relationship between the type of coping strategy adopted by adolescent girls and eating disorder score of them (P= 0.007). The relationship between coping strategy and body image and having or not having the eating disorder was determined by Chi-square test at the borderline level (P= 0.054). Conclusion: In this study, results showed that there is relationship between coping strategy of adolescent girls and the eating disorder score of adolescent girls. The highest score was assigned to getting involved with body image, followed by avoidance and rational acceptance. Since the use of inappropriate coping strategies is associated with negative results such as eating disorders and depression, it is expected that eating disorders resulting from mental body image to be reduced by management of people in using correct and appropriate coping strategies.
Progesterone Therapy for the Prevention of Preterm Labor in Women with Single Risk-factor: A Systematic Review and Meta-analysis Ara, Kefayat Chaman; Bahrami, Mohammad Amin; Bahrami, Elham; Bahrami, Sima; Bahrami, Mohammad Nabi; Moosazadeh, Mahmood; Barati, Omid
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Preterm labor is a common complication of pregnancy which has become a main health concern around the world due to its negative consequences. Objective: To investigate the efficacy of progesterone therapy in the prevention of preterm labor in women with single risk factor. Search strategy: A PubMed, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, Science Direct, Scopus, OVID, EMBASE, SID, Magiran and Google Scholar search (date last searched April 2016) without any time, language and location restriction was done. Inclusion criteria: All randomized clinical trials of singleton pregnancies with single risk factor (prior preterm labor without short cervical length or short cervical length without prior preterm labor) which were randomized to progesterone and control groups were included in our meta-analysis. Primary outcome: Our primary outcome was gestational age at delivery. Results: 13 studies (1259 subjects and 2653 control women) were included in the meta-analysis. Using random effect model showed that mean gestational age at delivery of progesterone group is 0.74 (0.41-1.06) month longer than that of control group with CI=95% which is significant statically. Conclusions: Progesterone therapy is an effective intervention for the prevention of preterm labor in women with single risk factor.
Association of P53 Protein Overexpression with Clinicopathological Features of Oral Squamous Cell Carcinoma Patients in Bali Winata, A.; Manuaba, I. B. Tjakra. W.; Sudarsa,, I. W.; Mahadewa, Tjok G. B.
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Oral cancer was a major health problem with a high incidence rate worldwide. Oral Squamous Cell Carcinoma (OSCC) in Bali, ranked as the second most common cancer after cervix carcinoma. Our understanding of OSCC hasn’t yielded a satisfactory clinical outcome; therefore, further studies about the role of biomolecular markers in OSCC are still needed. One of the biomolecular markers for prognosis and predictor for OSCC that has been a topic of research to date is p53. Method: This is a cross-sectional analytical study of 36 samples to determine the correlation between p53 overexpression with age group, tumor location, tumor stage, and tumor grade in OSCC patients. Data was processed descriptive and analytical using Chi-Square/Fisher 's Exact Test methods with a significance value of p
Chronic Granulomatous Tolosa-Hunt Syndrome (Case Report) Samatra, D. P.; Kesanda, I M. P.; Indrayani, I. A. A.
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Tolosa-Hunt syndrome is a rare case, characterized by tenderness, persistent around the affected eye and ophthalmoplegia /paresis caused by granulomatous inflammation in the cavernous sinus region, supra orbital or orbital fissure. Although spontaneous remission may occur, even corticosteroid therapy has a very satisfactory effect. However, relapse can occur after remission. We report a case of granulomatous Tolosa-Hunt syndrome in women aged 47 years who suffer from recurrent Tolosa-Hunt syndrome attacks for 4 years on his left eye, there was a significant recovery after receiving steroid therapy. Case: We report A 47 years old with recurrent pain in the left eye since 4 years, pain episode duration of 1-2 weeks, accompanied by double vision when having long or short distance viewing, and when climbing stairs. The patient left eye was protruded with blurred vision and difficulty in distinguishing green color. Left eye examination vision 1/300, green color discromatopsia, normal funduscopic, ptosis, with paresis eye movement toward the superior, inferior, nasal and temporal. C-reactive protein and erythrocyte sedimentation rate were slightly elevated. ANA test was positive. In visual evoked potential, it showed latency elongation of the left face. Head MRI with contrast showed a isointense protrusion on the left cavernous sinus in axial cuts in T1 and T2. Head MRI T1 with contrast on coronal, axial cuts showed the appearance of convex lesions around the left cavernous sinus that enhanced with contrast. Conclusions: The result was clinically and radiographically diagnosed as Tolosa-Hunt Syndrome (THS). Therefore, 10 mg dexamethasone therapy, 4 times a day for 3 days was lowered to three times on day 4, 2 times on the fifth day and one time at day 6. The patient showed clinical improvement. The patient continued 48 mg oral methylprednisolone therapy up to 3 weeks which then gradually decreased and planned head MRI 3 months later.

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