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Nusantara Medical Science Journal
Published by Universitas Hasanuddin
ISSN : 24609757     EISSN : 25977288     DOI : -
Core Subject : Science,
Materials Science & Nanotechnology Neuroscience
Nusantara Medical Science Journal (NMSJ) is an open access, peer-reviewed journal published by Faculty of Medicine, Hasanuddin University twice a year in June and December. NMSJ encompasses all basic and molecular aspects of medical sciences, with an emphasis on the molecular studies of biomedical problems and molecular mechanisms. Subjects suitable for publication include, but are not limited to the following fields of Cardiovascular; Allergy and immunology; Cancer and stem cells; Endocrinology; Gastroenterology; Tropical and Infectious Disease; and Internal medicine.
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Articles 5 Documents
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Search results for , issue "Volume 4 No. 2 Juli - Desember 2019" : 5 Documents clear
RETRACTED: Efek Ekstrak Daun Mimba Terhadap Aktivitas SGPT Tikus Putih Jantan Galur Wistar Yang Telah Diinduksi Parasetamol Dosis Tinggi Eric Hartono Tedyanto; Sulistiana Prabowo
Nusantara Medical Science Journal Volume 4 No. 2 Juli - Desember 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i2.5987

Abstract

This article has been RETRACTED
The protective effect of Paliasa (Kleinhovia hospita L.) leaf extract against elevated total bilirubin serum induced by toxic dose of antituberculosis in rats Yulia Yusrini Djabir; Imelda Dhea Meylin; Rosany Tayeb
Nusantara Medical Science Journal Volume 4 No. 2 Juli - Desember 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i2.6474

Abstract

Liver dysfunction is implicated with the use of Antituberculosis (AT) leading to low compliance of TB patients to AT regimen. One of biomarker that is important to measure liver dysfunction is total bilirubin serum. Paliasa leaves have been emiprically used to improve liver function in South Sulawesi. This study aimed to determine the effect of ethanolic extract of Paliasa leaves on total bilirubin serum in rats. Twenty rats were devided into five groups: Group I served as the healthy control was only given NaCMC suspension, group II was treated with 178 mg/200gBB of AT suspension, while group III, group IV and group V  were given Paliasa extract 125 mg/kgBB, 250mg/kgBB and 500 mg/kgBB, respectively, 4 hours prior to AT suspension administration. Treatments were performed once a day for 28 days. Blood sampling was carried out 24 hours following the last treatment. The total bilirubin levels were measured using Humalyzer 3500. The results showed that the administrations of AT suspension for 28 days significantly increased rat total bilirubin levels. Paliasa leaf extract in all given dose was able to reduce the total bilirubin levels of rats compared to the group given only AT suspension. However, statistical significance was only reached by the groups that were treated with Paliasa extract 250 and 500 mg/kgBB. Therefore it is concluded that ethanol extract at a dose of 250 and 500 mg/kgBB has protective effect against AT-induced elevation of total bilirubin serum in rats.
Pengaruh Pemberian Eccentric Strengthening Exercises Terhadap Perubahan Foot Alignment, Malleolus Height Dan Tingkat Agility Pada Pemain Bulu Tangkis Junior Di Kota Makassar Hermilasari Hermilasari; Adi Ahmad Gondo; Irianto Irianto
Nusantara Medical Science Journal Volume 4 No. 2 Juli - Desember 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i2.6524

Abstract

Foot alignment merupakan keselarasan sumbu vertikal tubuh terhadap posisi normal kaki yang dapat mempengaruhi keselarasan mekanis dan fungsi dinamis ekstremitas inferior yang dapat memberikan dukungan dan menjaga keseimbangan tubuh. Malalignment pada struktur kaki menunjukkan adanya gangguan biomekanik, seperti overpronation memungkinkan terjadi perubahan struktur dan fungsional tubuh yang dapat mempengaruhi ekstremitas inferior dan ekstremitas superior. Penelitian ini bertujuan untuk mengetahui pengaruh Eccentric Strengthening Exercises terhadap perubahan Foot Alignment, Malleolus Height dan Tingkat Agility. Penelitian ini merupakan penelitian quasi-experimental design dengan rancangan penelitian time-series experimental design. Populasi penelitian adalah pemain bulu tangkis junior di Kota Makassar usia 11-15 tahun. Pengambilan sampel menggunakan teknik purposive sampling dengan jumlah sampel 32 orang. Pengumpulan data dilakukan melalui pengambilan data primer melalui instrumen pengukuran foot alignment , malleolus height dan agility. Data yang terkumpul dilakukan uji normalitas menggunakan Shapiro Wilk Test. Sebaran data berdistribusi normal. Kemudian dilakukan uji perbedaan pre test dan post test menggunakan uji repeated anova untuk data berdistribusi normal dan uji friedman untuk data berdistribusi tidak normal. Dari hasil pengukuran diperoleh nilai signifikan p=0,0001 (p<0,05) setelah 18 kali pemberian latihan. Penelitian menunjukkan bahwa adanya pengaruh eccentric strengthening exercise terhadap perubahan foot alignment, malleolus height dan tingkat agility pada pemain bulu tangkis junior di kota makassar.
Perbandingan Pengaruh Kombinasi Latihan Hold Relax Dan Open Kinetic Chain Dengan Latihan Hold Relax Dan Close Kinetic Chain Terhadap Peningkatan Kemampuan Fungsional Pasien Osteoartritis Knee Khairurizal Khairurizal; Irianto Irianto; Yonathan Ramba
Nusantara Medical Science Journal Volume 4 No. 2 Juli - Desember 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i2.6564

Abstract

Osteoartritis knee adalah salah satu penyakit yang disebabkan oleh faktor degenerasi yang paling sering dijumpai pada penyakit musculoskeletal. Keluhan yang sering dialami yaitu kombinasi antara nyeri sendi, kekakuan, ketidakstabilan, pembengkakan, dan kelemahan otot. Osteoartritis knee merupakan salah satu faktor predisposisi yang menyebabkan kecacatan dan penurunan level fungsional seseorang. Penelitian ini bertujuan untuk membandingkan pengaruh kombinasi latihan hold relax dan open kinetik chain dengan latihan hold relax dan close kinetic chain terhadap peningkatan kemampuan fungsional pada pasien osteoartritis knee. Penelitian yang digunakan adalah quasi experimental dengan one group pretest-postetst design. Teknik pengambilan sampel yaitu purposive sampling dengan jumlah sampel sebanyak 26 orang yang memenuhi kriteria inklusi. Pada penelitian ini digunakan 2 kelompok perlakuan, yaitu kelompok perlakuan 1 hold relax dan open kinetic chain sebanyak 13 orang, kelompok perlakuan 2 hold relax dan close kinetic chain sebanyak 13 orang. Kedua kelompok sampel diukur kemampuan fungsionalnya menggunakan WOMAC. Latihan dilakukan sebanyak 9 kali perlakuan selama 3 minggu. Analisis pengaruh dilakukan dengan uji paired sample T test pada kelompok 1 dan pada kelompok 2. Uji paired sample t-test pada kelompok 1 hold relax dan open kinetic chain diperoleh nilai p=0,000 ( p<0,05 ). Sedangkan pada kelompok perlakuan 2 hold relax dan close kinetic chain diperoleh nilai p=0,000 (p<0,05) yang berarti ada pengaruh pada kemampuan fungsional sebelum dan sesudah perlakuan. Dari hasil pengujian dengan Independent t-test didapatkan nilai p=0,000 (p<0,05) yang berarti ada perbedaan pengaruh hold relax dan open kinetic chain dengan hold relax dan close kinetic chain terhadap peningkatan kemampuan fungsional pasien osteoartritis knee.
Profile And Treatment of Stevens-Johnson Syndrome Patients in DR. Soetomo General Hospital Anggun Tera Rahmasari; Diah Mira Indramaya; Pudji Lestari
Nusantara Medical Science Journal Volume 4 No. 2 Juli - Desember 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i2.5696

Abstract

Background: Stevens-Johnson Syndrome (SJS) is a rare but potentially life- threatening form of Severe Cutaneous Adverse Reaction (SCAR). SJS is mostly caused by drugs and is associated with high morbidity and mortality. Moreover, no standard treatment has been established for SJS. The aim of this study is to present epidemiological features, etiologies, clinical outcomes, medical histories, and treatments of SJS patients at the Inpatient Units Kemuning I and II Dr. Soetomo General Hospital between 2011 until 2015.Methods: This retrospective study used secondary data collected from medical records. All patients in the Inpatient Units Kemuning I and II of Dr. Soetomo General Hospital from the year 2011 until 2015 who was diagnosed SJS were included in this study.Result: There were 29 medical records consisting of 23 females and 6 males with the diagnosis of SJS found in 2011-2015. Most patients were aged 25-44 years old, with no family history of SJS. A majority first presented with a clinical history of fever. The main cause of SJS in this cohort was amoxicillin. Mucosal areas that were involved the most was the eye and mouth. Systemic treatments for patients were corticosteroid. The average duration of treatment was 15,88 days. None of the patients died.Conclusion: SJS was more common in females compared to males. The main systemic therapy in Inpatient Units Kemuning I dan II of Dr. Soetomo General Hospital was intravenous cortiosteroid and no patients died.

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