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Smart Medical Journal
ISSN : 26211408     EISSN : 26210916     DOI : -
Core Subject : Health,
Smart Medical Journal (SmedJour) is published by Faculty of Medicine Universitas Sebelas Maret. SMedJour publishes original research articles or article review in the basic medical sciences, clinic medical sciences, medical education and public health.
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Articles 100 Documents
Konsensus Dokter Umum Mengenai Materi Inti Anatomi Sistem Reproduksi Wanita Untuk Mahasiswa Kedokteran INTAN PRATIWI; YUNIA HASTAMI; NANANG WIYONO; SITI MUNAWAROH
Smart Medical Journal Vol 1, No 2 (2018): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.187 KB) | DOI: 10.13057/smj.v1i2.28706

Abstract

Introduction: The anatomy of the female reproductive system is one of the basic sciences of medical clinical practice needed by general practitioners. Until now there has been no standardization regarding anatomical material of the female reproductive system that medical students need to know. Meanwhile, the medical curriculum has undergone many changes that have impacted on reduced learning time resulting in a reduction in anatomical material given to students. This causes the different emphasis on anatomical material given to be different for each medical institution. This study aims to compile the subject matter of the anatomy of the female reproductive system in order to facilitate anatomical learning for medical students. Methods: This research is a qualitative research with Delphi method two rounds. The subjects were general practitioners from 9 institutions in Indonesia selected through purposive sampling as many as 20 people. The initial Delphi questionnaire was compiled based on three anatomical textbooks, one anatomic terminology, and one study on the anatomical core material. Delphi round I panel is asked to choose material that are important and can add material if it doesn't already exist. Delphi round II panel was asked to rank 1-4 in each material. Researchers set a consensus level of 53%.Results: The results of Delphi round I obtained 176 materials from a total of 178 materials and no additional material was obtained. Delphi round II obtained 84 (47.72%) core anatomical materials from 176 material.Conclusion: General practitioners consensus of core materials of female reproductive system anatomy is 84 materials.
Profil Sindrom Aspirasi Mekonium pada Bayi Baru Lahir di RSUD Dr. Soetrasno Rembang Ahimsa Yoga Anindita; Dwi Hidayah; Yulidar Hafidh; Annang Giri Moelyo; Mayasari Dewi
Smart Medical Journal Vol 1, No 2 (2018): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.241 KB) | DOI: 10.13057/smj.v1i2.28692

Abstract

Introduction: The presence of meconium in amniotic fluid occurs in 13% of live births in developing countries. This condition develops when the gestational age increases at delivery. Meconium aspiration syndrome occurs in 5% of newborns in meconium stained amniotic fluid. The aim of this study is to determine the profile of newborns who experience meconium aspiration syndrome (MAS) who are treated at Dr. Soetrasno Hospital, Rembang and its outcome.Methods: Prospective study, data were obtained from medical records of Dr. Soetrasno Hospital, Rembang during September to October 2018, on newborns with MAS.Results: Of 12 newborns with MAS were obtained, consisting of 7 (58.3%) male and 5 (41.7%) female. All cases were term infants (gestational age above 37 weeks) and normal birth weight (above 2500 grams). Based on the first minute APGAR score, there were 4 newborns had score 1 and 2, respectively (33.3%). Based on the fifth minute APGAR score, there were 7 newborns had score 3 (58.3%). The outcome of newborns with MAS were 7 alive (58.3%) and 5 died (41.7%).Conclusion: There were 12 newborns suffering from MAS (54.5%) of 22 babies hospitalized at the NICU dr. Soetrasno Hospital Rembang. All newborns with MAS were term infants and normal birth weight. There were 5 newborns with MAS which required invasive mechanical ventilation (intubation) and all died (41.7%). 
PENGARUH PEMBERIAN EKSTRAK ETANOLIK AKAR KELOR (Moringa oleifera, Lam) TERHADAP KADAR ASAM URAT DAN INFILTRASI SEL RADANG JARINGAN GINJAL TIKUS PUTIH (Rattus norvegicus) MODEL DIET TINGGI LEMAK DAN INDUKSI STREPTOZOTOCIN-NICOTINAMIDE YNES AULIA EKA DAMAYANTI; RIZA NOVIERTA PESIK; WIDARDO WIDARDO; DYAH RATNA BUDIANI
Smart Medical Journal Vol 2, No 2 (2019): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1479.216 KB) | DOI: 10.13057/smj.v2i2.37941

Abstract

Latar Belakang. Insidensi obesitas yang tinggi akibat diet tinggi lemak serta keadaan hiperglikemia menyebabkan stress oksidatif yang berujung pada infiltrasi sel radang di ginjal dan hiperurisemia. Fitokimia akar kelor bersifat antioksidan dan antidiabetik pada jaringan hepar, pankreas dan ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak akar kelor terhadap kadar asam urat dan infiltrasi sel radang jaringan ginjal tikus putih model diet tinggi lemak dan induksi streptozotocin-nicotinamide.Metode. Penelitian eksperimental laboratorik dengan pretest-postest control group design untuk kadar asam urat dan postest only control group design untuk infiltrasi sel radang jaringan ginjal. Tikus jantan galur Wistar 30 ekor dibagi random menjadi 5 kelompok. K(1) kontrol negatif diberi pakan standard, K(II) diinduksi pakan tinggi lemak dan streptozotocin-nicotinamide, K(III), (IV) dan (V) setelah induksi diberi variasi dosis ekstrak akar kelor 150, 250 dan 350 mg/kgBB selama 28 hari. Kadar asam urat diukur dengan Spektrofotometer kit DiaSys selama empat kali. Analisis hasil dengan one-way ANOVA dan post hoc Tukey HSD test serta repeated ANOVA dilanjutkan pairwise comparison Bonferroni. Persentase infiltrasi sel radang jaringan ginjal dianalisis dengan Kruskal-wallis dan post hoc Man whitney test. Analisis hubungan keduanya menggunakan Spearman.Hasil: Terdapat perbedaan yang bermakna antara semua waktu pengukuran kadar asam urat (p < 0.05, kecuali kelompok K3 antara hari ke-25 dan hari ke-57). Terdapat perbedaan signifikan kadar asam urat setelah pemberian ekstrak akar kelor antar kelompok. Terdapat perbedaan signifikan setelah diberikan ekstrak akar kelor pada persentase infiltrasi sel radang jaringan ginjal glomerulus antara K(I) dengan K(II), K(II) dengan K(V); dan antara K(II) dan K(V) pada jaringan ginjal tubulus. Persentase infiltrasi sel radang jaringan ginjal dan kadar asam urat setelah pemberian ekstrak akar kelor menunjukan hubungan yang bermakna dan berkorelasi positif kuat.Simpulan: Ekstrak akar kelor dengan dosis 150, 250 dan 350mg/kgBB menurunkan kadar asam urat darah, dan dosis 350mg/kgBB mampu menurunkan infiltrasi sel radang jaringan ginjal.Kata Kunci: Ekstrak akar kelor; asam urat; infiltrasi sel radang; pakan tinggi lemak; Streptozotocin-NicotinamideBackground: The high incidence of obesity due to a high-fat diet and hyperglycemia causes oxidative stress which can lead to infiltration of inflammatory cells in the kidneys and hyperuricemia. Phytochemicals of Moringa root are antioxidant and antidiabetic in liver, pancreas and kidney tissue. This study aims to determine the effect of Moringa root extracts on uric acid levels and inflammatory cell infiltration of white rat kidney tissue in high-fat diet models and induction of streptozotocin-nicotinamide.Methods: Laboratory experimental research with pretest-posttest control group design for uric acid levels and posttest only control group design for infiltration of inflammatory cells of kidney tissue. Samples of 30 Wistar strain male rats were randomly divided into 5 groups. K(1) negatie control was given standard feed, K(II) was induced by high-fat feed and streptozotocin-nicotinamide, K(III), (IV) and (V) after induction was given various dosage variations of Moringa root extract 150 mg / kgBW, 250 mg / kg kgBB and 350 mg / kgBB for 28 days. Uric acid levels were measured with a DiaSys kit spectrophotometer four times. The results were analyzed by one-way ANOVA test and post hoc Tukey HSD test and repeated ANOVA test followed by pairwise comparison Bonferroni test. The percentage of inflammatory cells infiltration of kidney tissue was analyzed by the Kruskal-wallis test and the post hoc Man Whitney test. The relationship between the two was tested using the Spearman testResults: There was a significant difference between all time measurements of uric acid levels (p <0.05, except for the K3 group between the 25th day and 57th day). There was a significant difference in uric acid levels after administration of Moringa root extract between groups. There was a significant difference after Moringa root extract was given in the percentage of inflammatory cells infiltration of glomerular kidney tissue between K (I) with K (II), K (II) with K (V); and between K (II) and K (V) in tubular kidney tissue. The percentage of inflammatory cells infiltration of kidney tissue and uric acid levels after administration of Moringa root extract showed a significant relationship and a strong positive correlation.Conclusion: Moringa root extract with a dose of 150 mg / kgBW, 250 mg / kgBW and 350 mg / kgBW significantly reduced uric acid levels, and with a dose of 350 mg / kgBW significantly reduced infiltration of inflammatory cells of kidney tissue.Keywords: Moringa root extract; uric acid; infiltration of inflammation cells; high-fat feed; Streptozotocin-Nicotinamide
DIAPHRAGMATIC RUPTURE AN EMERGENCY CASE REPORT IFADA INDRIYANI; WIDIASTUTI WIDIASTUTI; THARINA LAWEI; DARMAWAN ISMAIL
Smart Medical Journal Vol 2, No 2 (2019): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.254 KB) | DOI: 10.13057/smj.v2i2.38518

Abstract

 ABSTRACTIntroduction: Diaphragmatic rupture is a major challenge for the radiologist to be confirmed as an emergency diagnosis. The prevalence of the injury is 5% of abdominal blunt force trauma cases. Left-sided injury is more common with left-to-right ratio 3:1. Chest X-Ray is a conventional modality as an early assessment of abdominal trauma and computed tomography is a standard reference to confirm this diagnosis.Case Report: A 70 yo man complained about chest pain after falling from 4 meter-height tree. Chest X-Ray revealed bowel gas appearance in the left thorax cavity with no appearance of left diaphragm. Contrasted abdominal CT showed gaster and intestine in the left thorax cavity. The patient underwent left diaphragm thoracotomy confirming the existence of gaster, ileum, and spleen in the pleural cavity. Those organs were returned to the abdomen and the left diaphragm repaired. Following-up after discharge obtained remarkable outcomes.Discussion: Confirming the diagnosis of diaphragmatic rupture is a challenge for the radiologist because it can be asymptomatic until life-threatening complications manifest such as respiratory disorders and visceral incarceration.Conclusion: With the improvement of imaging technology, the radiologist is able to confirm a diaphragmatic rupture to get a better prognosis.  Key words: diaphragmatic rupture; trauma; chest X-ray; computed tomography ABSTRAK Pendahuluan : Konfirmasi diagnosis emergensi ruptur diafragma masih menjadi tantangan bagi spesialis radiologi. Prevalensi ruptur diafragma sebesar 5% dari kasus trauma tumpul abdomen dan perlukaan diafragma pada sisi kiri lebih umum terjadi dibandingkan sisi kanan dengan rasio 3:1. Foto X-Ray dada merupakan modalitas konvensional sebagai penilaian awal trauma abdomen dan computed tomography scanning (CT scan) merupakan standar pemeriksaan untuk mendiagnosis kasus tersebut.Laporan Kasus : Seorang laki-laki berusia 70 tahun mengeluhkan nyeri dada setelah jatuh dari pohon setinggi 4 meter. X-ray dada menunjukkan gambaran gas usus di sebelah kiri rongga thorax dan tidak tampak gambaran diafragma kiri. CT scan abdomen dengan kontras menunjukkan gambaran lambung dan usus di sebelah kiri rongga thorax. Pasien tersebut kemudian ditatalaksana dengan thorakotomi diafragma kiri untuk mengkonfirmasi adanya lambung, ileum dan lien pada rongga pleura. Organ-organ tersebut kemudian dikembalikan ke dalam abdomen dan diafragma kiri direparasi. Kondisi klinis pasien setelah penatalaksanaan tersebut menunjukkan perbaikan.Diskusi : Konfirmasi diagnosis ruptur diafragma merupakan tantangan bagi spesialis radiologi karena kasus tersebut bisa tidak bergejala sampai timbulnya komplikasi yang mengancam jiwa seperti gangguan respirasi dan perlekatan organ visceral.Kesimpulan : Dengan adanya perkembangan teknologi pencitraan, spesialis radiologi dapat mengkonfirmasi ruptur diafragma sehingga memberikan prognosis yang lebih baik. Kata Kunci : ruptur diafragma; trauma; chest X-ray, computed tomography
BODY IMAGE AND RELIGIOSITY IN ADOLESCENTS: A COMPARATION BETWEEN PUBLIC AND PRIVATE HIGH SCHOOL STUDENTS WIDANA PRIMANINGTYAS; ANAK AGUNG ALIT KIRTI ASTUTI NARENDRA PUTRI; HENI HASTUTI
Smart Medical Journal Vol 2, No 2 (2019): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.416 KB) | DOI: 10.13057/smj.v2i2.35672

Abstract

ABSTRACTBackground: There are many literatures have reported the link between religiosity and health outcomes. Body image come as someones’ perceptions towards their body, also being influenced by religiosity. The aims of this study was to compare body image in adolescents between private (Islamic) and public (mix religion) high schools, beside the similar study in Indonesia have not yet reported. Method: This was a cross sectional design study using Body Shape Questionnaire (BSQ) and Duke University Religion (Durel) Index questionnaire. We used purposive sampling for sampling technique. The data collected from one private (I) and one public (II) senior high schools in Surakarta, Indonesia.  An independent-samples t test was conducted to compare the BSQ score and Durel index between both schools.  Result: Total 150 questionnaires were distributed to both schools, only 116 questionnaires filled completely. There was a significant difference in the Durel index between school I (M=25.90, SD=2.82) and II (M= 24.70, SD=1.55); t(114)= 2.84, p=0.005. But there was not a significant difference in the BSQ score between school I (M= 77.00, SD=26.16) and II (M= 79.86, SD=26.67); t(114)=-0.58, p=0.561. Conclusion: These results showed that the students who studying in a private senior high school have a higher religiosity compare to those who studying in public senior high school. The higher religiosity in private schools’ gave them lower score on BSQ compare to public schools’, but the mean differences were not statistically significant. Keywords: body image; adolescents; body shapeABSTRAKBackground: Religiusitas dan hubungannya dengan outcome kesehatan telah dibahas dalam berbagai studi. Salah satu outcome kesehatan yang berhubungan dengan religiusitas adalah body image. Tujuan dari studi ini adalah untuk membandingkan body image pada remaja di sekolah menengah atas privat (Islami) dan sekolah umum (berbagai agama). Studi ini di Indonesia masih belum banyak ditemukan publikasinya.Metode: Studi ini adalah studi observasional analitik dengan pendekatan cross sectional. Dua kuisioner digunakan sebagai alat ukur penelitian yaitu Body Shape Questionnaire (BSQ) dan Duke University Religion (Durel) Index questionnaire. Teknik sampling yang digunakan adalah purposive sampling. Data penelitian didapatkan dari 1 sekolah menengah atas privat (I) dan 1 umum (II) di Surakarta, Indonesia. Untuk analisis data dalam studi ini digunakan Independent-samples t test  untuk membandingkan skor BSQ dan Durel index dari dua sekolah tersebut.Hasil: 150 kuisioner didistribusikan kepada remaja di kedua sekolah, hanya 116 kuisioner yang pengisiannya lengkap. Terdapat perbedaan yang signifikan dari skor Durel index antara sekolah I (M=25.90, SD=2.82) dan II (M= 24.70, SD=1.55); t(114)= 2.84, p=0.005. Untuk skor BSQ antara sekolah I (M= 77.00, SD=26.16) dan II (M= 79.86, SD=26.67); t(114)=-0.58, p=0.561, ditemukan perbedaan mean, namun tidak signifikan secara statistik.Kesimpulan: Hasil dari studi ini dapat menggambarkan bahwa remaja yang bersekolah di sekolah menengah atas privat mempunyai religiusitas yang lebih tinggi daripada di sekolah umum. Remaja di sekolah privat dilihat dari nilai Mean, mempunyai hasil body image yang lebih baik berdasarkan skor BSQ dibandingkan dengan sekolah umum, namun tidak signifikan secara statistik.Keywords: body image; remaja; bentuk tubuh
EFEK HYPOTHYROIDISME TERHADAP KETERLAMBATAN USIA MENARCHE SINU ANDHI JUSUP; SETYO SRI RAHARJO; JAROT SUBANDONO; ENDANG LISTYANINGSIH
Smart Medical Journal Vol 2, No 2 (2019): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v2i2.34602

Abstract

ABSTRAK Pendahuluan : Hormon Tiroid memiliki peran yang penting terhadap perkembangan dan fungsi organ reproduksi wanita. Pasien wanita dengan hipotiroidisme seringkali mengalami abnormalitas pada sistem reproduksi, termasuk terlambatnya usia menarche, gangguan siklus haid dan gangguan kesuburan. Mekanisme abnormalitas menstruasi pada hipotiroidisme belum sepenuhnya diketahui. Tujuan penelitian untuk mengetahui gangguan fungsi sistem reproduksi lebih awal, sehingga penanganan gangguan reproduksi lanjut dapat di cegah.Metode : Penelitian ini merupakan penelitian observasional analitik dengan metode cross sectional. Penelitian ini dilakukan di kecamatan Ngargoyoso, kabupaten Karanganyar dengan jumlah sampel 80 sampel yaitu 40 sampel untuk kelompok hipotiroidisme (+) dan 40 sampel untuk kelompok hipotiroidisme (-). Diagnosis hipotiroidisme dilakukan dengan menggunakan Zulewski’s Clinical Scoring dengan kriteria WHO/ICCIDD. Data yang diperoleh dianalisis menggunakan uji t. Hasil : Pada group hipotiroidisme (+) kelompok usia terbanyak usia 40-45 tahun (35%). Mayoritas memiliki pekerjaan petani (40%) dan ibu rumah tangga (37,5%). Pendidikan terakhir SLTP (40%) dan diikuti dengan pendidikan terakhir SD (32,5%).Rata rata usia menarche pada group hipotyroidisme (+)  (14,08 tahun ), lebih tinggi dibanding group hipotyroidisme (-)  (12,53 tahun), namun secara statistik perbedaan usia menarche pada kedua group itu tidak signifikan (p=0,098).Kesimpulan Status hipotyroidisme (+) tidak berpengaruh secara signifikan terhadap permulaan usia menarche.  Kata Kunci: hipotiroidisme; menarche;hormon thyroidABSTRACT Introduction. Thyroid hormones have an important role in the development and function of the female reproductive organs. Female patients with hypothyroidism often experience abnormalities in the reproductive system, including the late age of menarche, menstrual cycle disorders and fertility disorders. The mechanism of menstrual abnormalities in hypothyroidism is not yet fully known. The aim to know the reproductive system dysfunction earlier, so treatment of advanced reproductive disorders can be prevented. Method. This study was an observational analytic study with case control method. This research was conducted in Ngargoyoso sub-district, Karanganyar district. The samples were womens 20-45 years old,  40 samples for the hypothyroidism (+) group  and 40 samples for the hypothyroidism (-) group. The diagnosis of hypothyroidism was done using Zulewski’s Clinical Scoring with WHO / ICCIDD criteria. Patients with a score of 5 or more indicate hypothyroidism, while a score of 0-2 indicates euthyroid.  The data obtained were analyzed using the t test.Results. In the hypothyroidism (+) group  the most age group was 40-45 years old (35%). The majority have farmer jobs (40%) and housewives (37.5%). Whereas the last education was junior high school (40%) and was followed by the last primary education (32.5%). The average age of menarche in the hypothyroidism (+) group (14.08 years), was higher than the hypothyroidism (-) group  (12.53 years), but statistically the age difference in menarche in the two groups was not significant (p = 0.098).Conclusion. Hypothyroidism status didn’t significantly influence the onset of menarche. Hypothyroidism has no significant effect on the late age of menarcheKeywords: hypothyroidism; menarche; thyroid hormone    
PENGARUH PERSEPSI TENTANG IDENTITAS PROFESI TERHADAP SIKAP INTERPROFESSIONAL COLLABORATION TENAGA KESEHATAN DI PUSKESMAS ETI PONCORINI PAMUNGKASARI; SRI ANGGARINI PARWATININGSIH
Smart Medical Journal Vol 2, No 2 (2019): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (638.601 KB) | DOI: 10.13057/smj.v2i2.35199

Abstract

ABSTRAKPendahuluan: Kolaborasi tenaga medis merupakan hal yang penting dalam mengupayakan peningkatan kualitas pelayanan kesehatan. WHO menyampaikan bahwa kolaborasi akan memperkuat sistem kesehatan. Studi tentang kolaborasi tenaga medis di Indonesia terutama tentang tenaga medis Puskesmas masih sangat terbatas.Metode: Studi ini merupakan bagian dari pengabdian masyarakat,  dengan pendekatan cross sectional. Lokasi yang digunakan adalah Puskesmas Banyuanyar dan Puskesmas Kratonan, mewakili Puskesmas di kawasan pedesaan dan perkotaan. Tenaga kesehatan yang mengikuti kegiatan ini sebanyak 37 orang. Instrumen yang digunakan adalah kuesioner persepsi tentang identitas profesi, dan kuesioner sikap tentang interprofessional collaboration. Data yang didapatkan dianalisis statistik dengan uji regresi linier ganda.Hasil: Setiap peningkatan satu skor persepsi tentang identitas profesi akan meningkatkan sikap interprofessional collaboration sebesar 1,07; dan signifikan secara statistik (p = 0,001), setiap peningkatan satu tahun lama kerja akan menurunkan sikap interprofessional collaboration, namun tidak signifikan secara statistik (p=0,31). Persepsi tentang identitas profesi dan lama kerja bersama-sama mempengaruhi sikap interprofessional collaboration sebesar 31 %, sisanya sebesar 69 % dipengaruhi oleh faktor lain yang tidak diteliti, model regresi ganda fit dengan p=0,001.Kesimpulan: Persepsi tenaga kesehatan tentang identitas profesi mempengaruhi sikap tentang identitas profesi. Perlu memperkuat persepsi tenaga kesehatan tentang identitas profesi.Kata Kunci: kolaborasi; puskesmas; tenaga medis; identitas profesi ABSTRACTIntroduction: Collaboration of health care workers is important in order to improve the quality of health services. WHO states that collaboration will strengthen the health system. Studies on collaboration of health care workers in Indonesia, especially on public health center workers, are still very limited.Methods: This study was part of community service, with a cross sectional study approach. The locations used are Puskesmas Banyuanyar and Puskesmas Kratonan, representing public health center in rural and urban areas. There were 37 health workers who participated in this activity. The instrument used was a perception of professional identity, and attitudes about interprofessional collaboration. The data obtained were statistically analyzed using the multiple linear regression.Results: Every increase of one perception score about professional identity would increase interprofessional collaboration attitude by 1.07, statistically significant (p ≤ 0.001), every increase of one year of work would decrease interprofessional collaboration attitude, but not statistically significant (p = - 0.31). Perceptions of professional identity and length of work together affect interprofessional collaboration attitude by 31%, the remaining 69% is influenced by other factors not examined, the multiple fit regression model with p = 0.001.Conclusion: Health workers' perceptions about professional identity influence attitudes about professional identity. There is a need to strengthen the perception of health workers about professional identity. Keywords: collaboration; public health center; health care workers; professional identity
EFEK ANTI HISTAMIN EKSTRAK DAUN JAMBU BIJI PADA TIKUS PUTIH YANG DIINDUKSI OVALBUMIN DINILAI DARI JUMLAH EOSINOFIL JARINGAN KULIT RENDRA RISTIAN WIBOWO; RATIH DEWI YUDHANI; NOVAN ADI SETYAWAN
Smart Medical Journal Vol 2, No 2 (2019): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.38 KB) | DOI: 10.13057/smj.v2i2.33074

Abstract

                                                     ABSTRAKPendahuluan: Prevalensi dan keparahan penyakit alergi terus meningkat secara global, terutama di negara dengan pendapatan rendah sampai menengah. Terapi alergi saat ini seperti kortikosteroid banyak memberikan efek samping dalam penggunaan jangka panjang. Ekstrak daun jambu biji (Psidium guajava) berpotensi sebagai antihistamin yang dapat menjadi terapi alternatif penyakit alergi. Penelitian ini bertujuan untuk mengetahui efek antihistamin ekstrak daun jambu biji (Psidium guajava) pada tikus putih (Rattus novergicus) yang diinduksi ovalbumin dinilai dari jumlah eosinofil jaringan kulit.   Metode: Penelitian ini merupakan penelitian quasi experimental design dengan rancangan post test only with control group design. Subjek penelitian tikus putih jantan, umur 3-4 bulan, dan berat badan 200-300 gram. Sampel 24 ekor tikus putih dibagi secara random menjadi enam kelompok. Kelompok kontrol normal (K) tanpa perlakuan, kontrol negatif (KN) hanya diinduksi ovalbumin, kontrol positif (KP) diberikan metilprednisolon, dan kelompok perlakuan (KP1, KP2, KP3) diberikan ekstrak daun jambu biji dengan dosis berikut 27 mg/200 gramBB, 54 mg/200 gramBB, dan 108 mg/200 gramBB. Efek antihistamin dinilai melalui gambaran histopatologi jaringan kulit berupa rata-rata jumlah infiltrasi eosinofil dengan menggunakan mikroskop cahaya. Data dianalisis menggunakan uji Kruskal Wallis dan dilanjutkan uji Post Hoc Mann Whitney (α= 0,05).Hasil: Uji Kruskal Wallis menunjukkan perbedaan signifikan di antara enam kelompok perlakuan (p=0,00). Uji Post Hoc Mann Whitney menunjukkan perbedaan signifikan di antara semua pasangan kelompok (p=<0,05). KP3 menunjukkan rerata jumlah eosinofil lebih rendah daripada KP dan signifikan (p=0,021).  Kesimpulan: Ekstrak daun jambu biji (Psidium guajava) memiliki efek antihistamin dengan menurunkan infiltrasi eosinofil pada jaringan kulit tikus putih (Rattus norvegicus) yang dinduksi ovalbumin.Kata Kunci: Ekstrak daun jambu biji, eosinofil, tikus putih, histopatologi kulit. ABSTRACTIntroduction: The prevalence and severity of allergic diseases continues to increase globally, especially in countries with low to middle income. Current allergic therapies such as corticosteroids have many side effects in long-term use. Guava leaf extract (Psidium guajava) has the potential as an antihistamine which can be an alternative therapy for allergic diseases. This study aims to determine the effect of antihistamine extract of guava leaves (Psidium guajava) on white rats (Rattus novergicus) induced by ovalbumin assessed from the number of eosinophils of skin tissue. Methods: This research was a quasi experimental design with a post test only design with control group design. The research subjects were male white rats, aged 3-4 months, and weighing 200-300 grams. Samples of 24 white rats were randomly divided into six groups. Normal (K) control group without treatment, negative control (KN) was only induced by ovalbumin, positive control (KP) was given methylprednisolone, and treatment groups (KP1, KP2, KP3) were given guava leaf extract with the following dosage 27 mg / 200 gram BW, 54 mg / 200 gram BW, and 108 mg / 200 gram BW. The effect of antihistamines was assessed through histopathology of skin tissue in the form of an average number of eosinophil infiltrations using a light microscope. Data were analyzed using the Kruskal Wallis test and followed by the Mann Whitney Post Hoc test (α = 0.05).Result: The Kruskal Wallis test showed significant differences between the six treatment groups (p = 0.00). The Mann Whitney Post Hoc test showed significant differences between all group pairs (p = <0.05). KP3 shows the average number of eosinophils lower than KP and significant (p = 0.021). Conclusion: Guava leaf extract (Psidium guajava) has an antihistamine effect by reducing eosinophil infiltration in ovalbumin-induced white rat (Rattus norvegicus) skin tissue.Keywords: Guava leaf extract; eosinophil; skin histopathology
SOLUSI PERMASALAHAN MANAJERIAL DI SKILLS LAB ATIK MAFTUHAH
Smart Medical Journal Vol 2, No 2 (2019): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (610.104 KB) | DOI: 10.13057/smj.v2i2.35034

Abstract

Introduction: Learning clinical skills in the skills lab gives students the opportunity to learn and practice their clinical skills before examining directly to patients. However, the skills lab itself has many components that require good management and leadership to avoid obstacles or problems in the implementation of learning.Method: Literature review conducted through google and google scholar search engines with the keywords “leadership”, “management”, “team”, and “skills lab” from 1985-2015.Result: There are several concepts from literature study that can be applied to overcome managerial problems in the skills lab. An effective leader / manager profile according to Quinn (Quinn’s eight roles) is needed in leading the skills lab because the head of the skills lab as the first line manager is responsible for managerial problems in the skills lab. In addition, management and leadership in the skills lab is also very necessary to produce an effective and efficient team so that the performance and contribution of the management team is effective. By understanding the Belbin Team Roles, the concept can be adapted in managing the skills lab management by synergizing the roles among the members of the skills lab management team. Within this concept, there are eight aspects of roles in a good management team.Conclusion: Given the complexity in the skills lab, managerial problems can arise that can result in the preparation of modules, equipment, facilities, etc. being unprepared. Managerial problem solving in the skills lab can be solved by applying the manager's roles and functions, Quinn's eight roles and the Belbin team roles.Pendahuluan: Pembelajaran keterampilan klinis di skills lab memberikan kesempatan mahasiswa untuk belajar dan mempraktikkan keterampilan klinis mahasiswa sebelum terjun ke pasien langsung. Namun, skills lab sendiri memiliki komponen yang banyak sehingga memerlukan manajemen dan leadership yang baik supaya tidak terjadi kendala atau permasalahan dalam pelaksanaan pembelajaran.Metode: Literature review yang dilakukan melalui search engine google dan google scholar dengan kata kunci “leadership”, “management”, “team”, dan “skills lab” dari tahun 1985-2015.Hasil: Ada beberapa konsep dari studi literatur terpilih yang dapat diaplikasikan untuk mengatasi permasalahan manajerial di skills lab. Profil pemimpin/manajer yang efektif menurut Quinn (Quinn’s eight roles) sangat diperlukan dalam memimpin skills lab karena kepala bagian skills lab sebagai manajer lini pertama bertanggung jawab terhadap permasalahan manajerial di skills lab. Selain itu, manajemen dan leadership di skills lab juga sangat diperlukan untuk menghasilkan tim yang efektif dan efisien sehingga kinerja dan kontribusi tim pengelola menjadi efektif. Dengan memahami the Belbin Team Roles, maka konsep tersebut dapat diadaptasi dalam pengelolaan manajemen skills lab dengan melakukan sinergi peran diantara anggota tim pengelola skills lab. Dalam konsep tersebut, terdapat delapan aspek peran dalam sebuah tim manajemen yang bagus.Kesimpulan: Dengan adanya kompleksitas di skills lab, maka dapat timbul permasalahan manajerial seperti kurang siapnya modul, peralatan, fasilitas, dan lainnya. Penyelesaian permasalahan manajerial di skills lab dapat ditinjau dari aplikasi peran dan fungsi manajer, Quinn’s eight roles dan the Belbin team roles.
Effectiveness of Laser Acupuncture and Battlefield Acupuncture Therapy for Pain Management in Juvenile Idiopathic Arthritis : A Case Report Dwi Surya Supriyana; Arsita Eka Prasetyawati; Robby G Sebayang; Kemas Abdurrohim
Smart Medical Journal Vol 3, No 1 (2020): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.239 KB) | DOI: 10.13057/smj.v3i1.39378

Abstract

Introduction : Juvenile Idiopathic Arthritis (JIA) is a comprehensive chronic condition of a joint inflammatory autoimmune process, resulting a decrease of function in a long period characterized by fever and pain, which is include all form of unknown etiology that begin before 16 years old. Here we reported effectiveness of Laser Acupuncture and Battlefield Acupuncture Therapy for pain management in JIA case.Case report : A 10-year-old girl diagnosed with JIA was admitted to the pediatric department in Dr. Cipto Mangunkusumo Hospital, and treated by clinical multidisiplinary team from pediatrict, orthopedist, nutritionist, physiotherapist, and medical acupuncture doctor. She was referred to the Medical Acupuncture Department due to complaining of prolonged continous pain throughout her joints, and swelling in her right knee joint. The patient received laser acupuncture therapy in acupoints LI4 Hegu, LI11 Quchi, ST36 Zusanli, SP9 Yinliquan, and EX-LE5 Xiyan. Battlefield Acupuncture Points method (ears) of Omega2, Shenmen, Gyrus Cingulate, Thalamus, and Point Zero. The Therapy was given every day for two weeks and showed a significant improvement on patient’s Visual Analog Score.Conclusion : The combination regimen was effective in relieving pain and swelling, and caused a significant Visual Analog Score and Range of Motion improvement in our case. 

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