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Perbandingan Kejadian Post Dural Puncture Headache pada Pasien Seksio Sesarea dengan Anestesi Spinal Menggunakan Teknik Median dan Paramedian , Rizki; , Suwarman; Bisri, Tatang
Majalah Anestesia dan Critical Care Vol 32 No 2 (2014): Juni
Publisher : Perdatin Pusat

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Abstract

spinal (LCS) berpengaruh terhadap timbulnya PDPH. Berbagai faktor yang memengaruhi insidensi kejadian PDPH, meliputi jenis kelamin, usia, kehamilan, riwayat PDPH sebelumnya, ukuran dan bentuk jarum, arah jarum, jumlah percobaan tusukan, teknik penusukan median atau paramedian, dan keahlian ahli anestesi. Tujuan penelitian adalah membandingkan kejadian PDPH wanita hamil yang dilakukan seksio sesarea dengan anestesi spinal menggunakan teknik median dan paramedian di RS Dr. Hasan Sadikin Bandung, periode Maret–April 2014. Penelitian ini dilakukan secara uji klinis acak terkontrol tersamar tunggal terhadap 44 pasien wanita hamil aterm dengan status fisik American Society of Anesthesiologists (ASA) I dan II yang menjalani seksio sesarea dengan anestesi spinal. Subjek dibagi menjadi dua, kelompok paramedian (P) dan kelompok median (M). Kelompok P dilakukan penusukan menggunakan teknik paramedian dan kelompok M menggunakan teknik median dengan m jarum spinal ukuran 25-gauge tipe Quincke. Data hasil penelitian dianalisis menggunakan metode chi-kuadrat Hasil penelitian menunjukkan tidak ada perbedaan yang bermakna pada kedua kelompok (p=0,351), terdapat 2 kejadian (9%) PDPH pada kelompok median (n=22) dan tidak ditemukan kejadian pada kelompok paramedian (n=22). Simpulan penelitian ini adalah tidak ada pengaruh teknik penusukan menggunakan teknik paramedian atau median terhadap kejadian PDPH pada wanita hamil yang dilakukan seksio sesarea Kata kunci: Anestesi spinal, teknik paramedian, post dural puncture headache, teknik median Post dural puncture headache (PDPH) is an iatrogenic complication of spinal anesthesia. Cerebro spinal fluid (LCS) leak have effect on the incidence of PDPH. Various factors affect the incidence of PDPH include gender, age, pregnancy, history of previous PDPH, the size and shape of the needle, the needle direction, the number of attempted punctures, median or paramedian puncture technique, and skill of the operator. The purpose of this study was to compare the incidence of PDPH in pregnant women who performed caesarean section under spinal anesthesia using median and paramedian techniques in Dr. Hasan Sadikin Hospital Bandung at April-May 2014. This research was conducted in single-blind randomized controlled clinical trial on 44 at term pregnant women with American Society of Anesthesiologists (ASA) physical status I and II undergoing cesarean section with spinal anesthesia. Subjects were divided into two groups paramedian (P) and the median (M). Group P performed using paramedian puncture technique and M groups using the median technique. Both of technique using a 25- gauge Quincke needle. The data were analyzed using chi-square method The results of this study showed no significant difference in both groups (p=0.351) , with 2 incidences of PDPH (9 % ) in the group median (n=22) and not found in the paramedian group (n=22). Conclusions there is no difference between median and paramedian techniques on the incidence of PDPH in pregnant women who performed caesarean section. Key words: Median, paramedian, post dural puncture headache, spinal anesthesia Reference Paech MJ, Whybrow T. The prevention of anaesthesiology. Asean J Anaesth.2007;8:86–95. Amorim JA, Gomes de Barros MV, Valenca MM. Post-dural (post-lumbar) puncture headache: risk factors and clinical features. Cephalalgia. 2012 Sep;32(12):916−23. Singh J, Ranjit S, Shrestha S, Limbu T, Marahatta SB. Post dural puncture headache. J Inst Med. 2010;32(2):30−2. Mosaffa FK, Madadi F, Khoshnevis SH, Besheli LD, Eajazi A. Post-dural puncture headache: a comparison between median and paramedian approaches in orthopedic patients. Anesth Pain. 2011;1(2):66–9. Wu CL, Christo P, Richman JM, Hsu W. Postdural puncture headache: an overview. Int J Pain Med Pall Care. 2004;3(2):53–9. Turnbull DK, Shepherd DB. 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Clinical Manifestations of Iscehaemic and Reperfusion Injury Pradian, Erwin; , Rizki; Maskoen, Tinni Trihartini
Majalah Anestesia dan Critical Care Vol 33 No 2 (2015): Juni
Publisher : Perdatin Pusat

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Abstract

Although restoration of blood low to an ischaemic organ is essential to prevent irreversible tissue injury, reperfusionper se may result in a local and systemic inlammatory response that may augment tissue injury in excess of thatproduced by ischaemia alone. Cellular damage after reperfusion of previously viable ischaemic tissues is deinedas ischaemia-reperfusion (I-R) injury. I-R injury is characterized by oxidant production, complement activation,leucocyte endothelial cell adhesion, platelet-leucocyte aggregation, increased microvascular permeability anddecreased endothelium-dependent relaxation. In its severest form, I-R injury can lead to multiorgan dysfunctionor death. Although our understanding of the pathophysiology of I-R injury has advanced signiicantly in the lastdecade, such experimentally derived concepts have yet to be fully integrated into clinical practice. Treatment ofI-R injury is also confounded by the fact that inhibition of I-R-associated inlammation might disrupt protectivephysiological responses or result in immunosuppression. Thus, while timely reperfusion of the ischaemic areaat risk remains the cornerstone of clinical practice, therapeutic strategies such as ischaemic preconditioning,controlled reperfusion, and anti-oxidant, complement or neutrophil therapy may signiicantly prevent or limit I-Rinducedinjury in humans.