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All Journal Jurnal Kedokteran Jurnal Pengabdian Magister Pendidikan IPA JURNAL ILMU KEFARMASIAN INDONESIA Sasambo Journal of Pharmacy
Yohanes Juliantoni
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Education Health Professions Medicine & Pharmacology

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Formulasi Lotion Esktrak Etanolik Herba Ashitaba (Angelica Keiskei) sebagai Penangkal Radikal Bebas Wahida Hajrin; Yohanes Juliantoni
Jurnal Kedokteran Vol 8 No 2 (2019)
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v8i2.335

Abstract

Senyawa radikal dapat merusak serabut kalogen kulit dan matrik dermis sehingga kulit menjadi kering, keriput, bahkan dapat menjadi penuaan dini. Upaya pencegahan yang dapat dilakukan yaitu dengan penggunaan bahan yang memiliki aktivitas antioksidan. Salah satu tanaman yang memiliki aktivitas antioksidan adalah ashitaba. Metode yang digunakan pada penelitian ini adalah variasi pengeringan ashitaba untuk melihat pengaruhnya terhadap aktivitas penangkapan radikal DPPH dan kadar fenolik total ekstrak etanoliknya. Sampel dengan metode pengeringan yang lebih baik, digunakan untuk membuat sediaan lotion. Hasil penelitian menunjukkan sampel yang dikeringkan dengan oven memiliki rendemen lebih tinggi dari pada dengan sinar matahari. Aktivitas penangkapan radikal DPPH sampel oven dengan IC50 sebesar 350,24 µg/mL lebih baik dari pada sampel matahari yaitu sebesar 3979,46 µg/mL (p0.05). Hasil uji kadar fenolik total sampel oven sebesar 2,9817±0,0935 gEAG/100g lebih tinggi dari pada sampel matahari sebesar 1,7168±0,0142 gEAG/100g sampel. Sampel yang dikeringkan dengan oven kemudian diformulasi dalam bentuk sediaan lotion. Uji acceptabilitas menunjukkan ekstrak etanolik herba ashitaba cocok dibuat sediaan lotion. Ekstrak etanolik herba Ashitaba dapat dibuat sediaan lotion namun perlu dilakukan optimasi formula dan uji stabilitas untuk memperoleh sediaan lotion yang baik.
Antibacterial Activities from Gel Hand Sanitizer of Jatropha curcas Leaves Ethanolic Extract Against Staphylococcus aures ATCC 25923 Erviana Vernanda Margaretha; Yohanes Juliantoni; Dyke Gita Wirasisya
Sasambo Journal of Pharmacy Vol. 1 No. 1 (2020): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.453 KB) | DOI: 10.29303/sjp.v1i1.8

Abstract

Food borne disease is a disease with symptoms such as nausea, diarrhea and vomiting. The main cause of FBD was food contamination of Staphylococcus aureus. Jarak pagar (Jatropha curcas Linn) leave is a plant that have antibacterial activity against S. aureus because it contains saponin, flavonoid, and tannin. This research aimed to determine the antibacterial activity of the ethanolic extract of Jatropha curcas Linn. leaves, formulated them as gel hand sanitizer, and evaluated the antibacterial activity of the formula. The sample was collected, determined, and extracted with ethanol 70% using maceration, and the phytochemical screening conducted to the concentrate extract. The antibacterial activity test conducted by well diffusion method with concetration 50, 100, dan 150 mg/mL. Then the effective extract group has formulated to gel hand sanitizer. The gel hand sanitizer formula tested the antibacterial activity and physical properties by organoleptic, pH, stability, and spreadablility. The result showed that the extract with concentration 50, 100, dan 150 mg/mL has inhibition zone diameter was 9.9, 15.7, and 16.4 mm, respectively. The gel hand sanitizer of Jatropha curcas Linn extract was formulated by using 100 mg/mL concentration of extract. The gel was physically stable and had inhibition zone diameter was 15.6 mm
Optimasi formula sampo ekstrak daun pacar air (Impatiens balsamina L.) dengan kombinasi natrium lauril sulfat dan cocamide DEA Dila Ayu Lestari; Yohanes Juliantoni; Raisya Hasina
Sasambo Journal of Pharmacy Vol. 2 No. 1 (2021): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (551.94 KB) | DOI: 10.29303/sjp.v2i1.72

Abstract

Dandruff is an anomalous condition characterized by excessive exfoliation of the horny layer from the scalp. The leaves of the water henna plant (Impatiens balsamina L.) are one of the natural ingredients that have anti-dandruff properties, so they can be used as an active ingredient in making dandruff shampoo. The water henna leaves were extracted using the maceration method with ethanol 96%. Apart from the active ingredients, shampoo also has an important component, namely surfactants. The surfactant used in this study was a combination of sodium lauryl sulfate and cocamide DEA. The purpose of this study was to optimize the surfactant formula of sodium lauryl sulfate and cocamide DEA in water henna leaf extract shampoo. This research was a laboratory experimental research. Formula optimization was done through the Simplex Latice Design (SLD) method approach by making eight formulas. All formulas were evaluated for their physical properties including the foam height test and pH test. The data obtained were processed with Design Expert® software. Based on the physical evaluation of the water henna leaf extract shampoo, the results of the high foam test were 10,025 cm and a pH of 6,12. The results of the acceptability test of shampoo preparations including the parameters of color, smell, texture and viscosity received a fairly good response with the acquisition of values 3,1, 3,3, 3,9 and 4 with information 1 (very dislike), 2 (dislike), 3 (quite like), 4 (like) and 5 (really like). The optimum formula for the shampoo consisting of 5% water henna leaf extract, 1,1863% sodium lauryl sulfate, 19,814% cocamide DEA, 3% CMC, 0,5% citric acid, 0,5% methyl paraben, 0,15% menthol and distilled water had physical properties that meet the requirements of a good shampoo preparation.
Formulasi Gel Handsanitizer Minyak Atsiri Daun Sereh (Cymbopogon nardus) dengan Hidroxy Propyl Methyl Cellulose (HPMC) sebagai Gelling Agent Febriza Risti Widyastuthi; Eustachius Hagni Wardoyo; Yohanes Juliantoni
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 2 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.690

Abstract

Gel handsanitizer wich is sell in the market today is mostly alcohol-based. Repeated useas a handsanitizer can cause dryness and irritation skin. An option is, we can substitute an alcoholinto lemongrass oil (Cymbopogon nardus). There are three steps of the test, a preliminary test of oilconcentration, a test of the physical properties of the gel preparation and a modifi ed replication test.Based on the preliminary test, citronella essential oil can kill Escherichia coli bacteria at a concentrationof 5% and reduce Staphylococus aureus at 10% of concentration. The test of spread for gel in thephysical test is between 5.5-6 cm with pH 7-9 and the adhesion is 1 second.The modifi ed replica testshowed a signifi cant decrease in the number of bacterial colonies at each concentration formula ofthe three test groups. This signifi cance indicates the inhibition of bacteria caused by the use of handsanitizing gels. Based on the organoleptic test and antibacterial test of hand sanitizer gel a chosenconcentration is 10%. This concenrtration was liked by the public and could inhibit bacterial growth.
Sosialisasi DAGUSIBU Untuk Meningkatkan Rasionalitas Penggunaan Obat Bagi Masyarakat Kerandangan Desa Senggigi Wahida Hajrin; Windah Anugrah Subaidah; Yohanes Juliantoni
Jurnal Pengabdian Magister Pendidikan IPA Vol 3 No 2 (2020): .
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (483.478 KB) | DOI: 10.29303/jpmpi.v3i2.492

Abstract

Senggigi village community has limitations in obtaining information about health, one of which is DAGUSIBU. DAGUSIBU is a way to get, use, store and dispose of medicines properly. The aim of this socialization was to inform about DAGUSIBU to the community so that medicines can be used rationally. The method used in the socialization is the delivery of material and direct examples related to the use of medicines that require special methods. The participants were very enthusiastic to attend the socialization, as evidenced by the many questions related to DAGUSIBU raised. This socialization increased participant’s knowledge about DAGUSIBU, they understand how to get, use, store and dispose of medicines in the right way.
Co-Authors Dila Ayu Lestari Dyke Gita Wirasisya Erviana Vernanda Margaretha Eustachius Hagni Wardoyo Febriza Risti Widyastuthi Raisya Hasina Wahida Hajrin Wahida Hajrin Windah Anugrah Subaidah