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Dewi, Dewa AL
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Medicine & Pharmacology Public Health

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Relationship Of Nutritional Status With Degree And Type Of Anemia In Vegetarian Santoso, Yuliana S; Dewi, Dewa AL; Jong, FX Himawan H.
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 1, No 2 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.909 KB) | DOI: 10.33508/jwmj.v1i2.2024

Abstract

Introduction: A vegetarian that consumes only plant foods is at risk for anemia due to nutritional deficiencies, especially iron and vitamin B12. Aim : to identify the level of nutritional intake, nutritional status, degree of anemia and type of anemia in a vegetarian group and to analyze the relationship between nutritional status with degree and type of anemia. Method : This study used analytic research, with correlational study, through cross sectional approach. The sampling technique of this research was purposive sampling at Vihara Thien Bao (Maha Vihara) with sample of 38 people including inclusion and exclusion criteria. Data were analyzed by using Rank Spearman test to measure the correlational relationship between nutritional status with degree of anemia and the contingency coefficient test measure the correlational relationship between nutritional status with type of anemia. Result : Intake of energy (71.89%), carbohydrate (74.56%), fat (68.04%), protein (134.38%), vitamin B12 (98.83%) and iron (25,04%) for men. Intake of energy (65,42%), carbohydrate (69,21%), fat (63,94%), protein (100,48%), vitamin B12 (45,30%) and iron (27,67%) for women. These data were compared with RDA. P value for nutritional status correlation analysis with degree of anemia was 0,639 and p value for nutritional status correlation analysis with type of anemia was 0,851. Conclusion : There was a deficit of energy, carbohydrate, fat, and iron in both gender. Protein intake was excessive in man and normal in woman. Iron and vitamin B12 intake were adequate in man and deficient in woman. Energy intake was deficient in man and very deficient in women. The nutritional intake was less likely cause anemia. There was no correlation between nutritional status with degree and type of anemia
Difference Of Weight And Low-Density Lipoprotein (LDL) Level Of Rattus Norvegicus On Mediterranean Diet And Unsaturated Ketogenic Diet Tanuy, Ricky S; Dewi, Dewa AL; Dinata, Mulya
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 3, No 1 (2021): January
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v3i1.3004

Abstract

Introduction: Sedentary lifestyle continues to develop, which causes problems such asobesity and coronary heart disease. This is caused by an increase in body weight and LDLlevels that can be overcame with a Mediterranean diet or an unsaturated ketogenic diet.Purpose: To analyze the difference in weight and LDL of Rattus norvegicus on theunsaturated ketogenic diet and the Mediterranean dietMethod: this study was an experimental study on 30 Rattus norvegicus divided into threegroups (control, unsaturated ketogenic, and Mediterranean), each group is divided into two,according to the time of administration (two weeks and four weeks). After the interventionwas completed, bodyweight was calculated, and LDL levels were checked. Then, the data wasanalyzed with one-way ANOVA test. Results: The test results show p < 0.001 in the comparison between the three groups and p <0.05 for comparison in the unsaturated ketogenic group. The Mediterranean diet shows p>0.05, and the control diet leads p> 0.05. The data show that rapid weight loss (2 weeks) andreduction in LDL (in 4 weeks) in the unsaturated ketogenic diet is better than theMediterranean diet or control. For medium-term weight loss (4 weeks), the Mediterraneandiet is better than the neither saturated ketogenic diet nor control.Conclusion: There is a difference in weight and low-density lipoprotein (LDL) level ofRattus norvegicus on the Mediterranean diet and unsaturated ketogenic diet. This favorablecondition might minimize the probability risk of obesity and coronary heart disease.
DIFFERENCES OF MASS AND DIAMETER MUSCLE RATTUS NORVEGICUS IN GIVING KETOGENIC DIETS AND EXERCISE Danika, Andri; Dewi, Dewa AL; Sindrawati, Sindrawati
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 3, No 3 (2021): July
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v3i3.3343

Abstract

Introduction: Saturated ketogenic diet without exercise can lead to muscle mass decrease and disturb body metabolism. Therefore, the researcher is interested in discovering the differences between a saturated and unsaturated ketogenic diet with exercise to muscle mass and diameter. Purpose: This study aimed to analyze the difference in muscle mass and diameter of Rattus norvegicus, which were given a ketogenic diet and exercise. Method: This experimental research used Rattus norvegicus that had been adapted for two weeks. Rats are divided into five groups; control (K), a saturated ketogenic diet (P1), a saturated ketogenic diet with exercise (P2), an unsaturated ketogenic diet (P3), and anunsaturated ketogenic diet with exercise (P4). Upright running wheel exercise was given to the group with exercise for 10 minutes daily. The ketogenic diet was given with oral gavage. Muscle mass was examined in the second and fourth weeks. Muscle diameter was examined before treatment, second week, and fourth week. Results: There are differences in mass and diameter muscle Rattus norvegicus that givenketogenic diet and exercise (p=0,000). In second week, there are significant increase inmuscle diameter for saturated ketogenic diet without exercise (P1(p=0,000)) and significantdecrease in muscle diameter for three other group (P2(p=0,000), P3(p=0,001), P4(p=0,000)). In the fourth week, there is a significant increase in muscle diameter for an unsaturated ketogenic diet with exercise (P4). Conclusion: An unsaturated ketogenic diet with exercise could increase the mass anddiameter of quadriceps muscle at the end of this research. 
AFRICAN BITTER LEAF EXTRACT EFFECT ON EPITHELIUM THICKNESS OF SEMINIFEROUS TUBULES IN WISTAR RATS WITH DIABETES MELLITUS Lienardi, Aurellia R; Suwasanti, Niluh; Dewi, Dewa AL
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 3, No 4 (2021): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v3i4.3503

Abstract

Introduction: Diabetes mellitus (DM) is a metabolic disease that can cause complications in the form of damage to male reproductive organs, such as decreased sperm motility and cell count, impaired spermatogenesis, and erectile dysfunction. A measurement that can be done to detect male reproductive disorders is to measure the thickness of the seminiferous tubule epithelium. Herbal medicines can be used to support treating diabetes. Studies have claimed that African bitter leaf helps in treating DM and its complications.Purpose: This study aims to determine the effect of African bitter leaf extract on epithelium thickness of seminiferous tubules in rats with DM.Method: True Experimental with Post-Test Only Control Group Design using Rattus norvegicus. Rats were divided into five groups, with six rats in each group. Rats were administered with a single dose of alloxan 150 mg/kg BW/IP. Group K is diabetic rats given glibenclamide 0,63 mg/kg BW. Group P0 are diabetic rats given CMC 0,1% 0,7 ml. Group P1 are diabetic rats given African bitter leaf extract 100 mg/kg BW. Group P2 are diabetic rats given African bitter leaf extract 200 mg/kg BW. Group P3 are diabetic rats given African bitter leaf extract 400 mg/kg BW. Treatments were given with oral gavage for 14 days. Rats were dissected, and their testis was made as histological slides. Results are statistically tested with ANOVA.Results: The average epithelium thickness from group K are 79,61 μm, group P0 are 59,96 μm, group P1 are 71,87 μm, group P2 are 67,31 μm, group P3 are 63,95 μm showed significant result (p=0,000).Conclusions: African bitter leaf extract affects epithelium thickness of seminiferous tubules, with group K, shows the best result, followed by group P1.
Co-Authors Danika, Andri Dinata, Mulya Jong, FX Himawan H. Lienardi, Aurellia R Santoso, Yuliana S Sindrawati, Sindrawati Suwasanti, Niluh Tanuy, Ricky S