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All Journal The Indonesian Journal of Occupational Safety and Health Journal Of Widya Medika Junior
Dinata, Mulya
Department Of Public Health Science , Faculty Of Medicine Widya Mandala Catholic University Surabaya Jalan Dinoyo 42-44 Surabaya, East Java 60265
Health Professions Medicine & Pharmacology Public Health

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Difference Of Weight And Low-Density Lipoprotein (LDL) Level Of Rattus Norvegicus On Mediterranean Diet And Unsaturated Ketogenic Diet Tanuy, Ricky S; Dewi, Dewa AL; Dinata, Mulya
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 3, No 1 (2021): January
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v3i1.3004

Abstract

Introduction: Sedentary lifestyle continues to develop, which causes problems such asobesity and coronary heart disease. This is caused by an increase in body weight and LDLlevels that can be overcame with a Mediterranean diet or an unsaturated ketogenic diet.Purpose: To analyze the difference in weight and LDL of Rattus norvegicus on theunsaturated ketogenic diet and the Mediterranean dietMethod: this study was an experimental study on 30 Rattus norvegicus divided into threegroups (control, unsaturated ketogenic, and Mediterranean), each group is divided into two,according to the time of administration (two weeks and four weeks). After the interventionwas completed, bodyweight was calculated, and LDL levels were checked. Then, the data wasanalyzed with one-way ANOVA test. Results: The test results show p < 0.001 in the comparison between the three groups and p <0.05 for comparison in the unsaturated ketogenic group. The Mediterranean diet shows p>0.05, and the control diet leads p> 0.05. The data show that rapid weight loss (2 weeks) andreduction in LDL (in 4 weeks) in the unsaturated ketogenic diet is better than theMediterranean diet or control. For medium-term weight loss (4 weeks), the Mediterraneandiet is better than the neither saturated ketogenic diet nor control.Conclusion: There is a difference in weight and low-density lipoprotein (LDL) level ofRattus norvegicus on the Mediterranean diet and unsaturated ketogenic diet. This favorablecondition might minimize the probability risk of obesity and coronary heart disease.
ANTIBACTERIAL ACTIVITIES TEST OF RED GINGER (Zingiber officinale var. rubrum) ETHANOL EXTRACT ON STAPHYLOCOCCUS EPIDERMIDIS Budianto, Andrea; Dinata, Mulya; Isbandiati, Endang
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 2 (2022): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v4i2.3791

Abstract

Background: Antibiotic is a drug often used against infections caused by bacteria; however, irrational use of antibiotics can cause multidrug resistance (MDR). Staphylococcus epidermidis is a bacteria that has developed an MDR characteristic against antibiotics. Staphylococcus epidermidis is a normal opportunistic flora. Said bacteria can produce a biofilm that enables the bacteria to adhere to prosthetic devices and enter the bloodstream. Red ginger (Zingiber officinale var. rubrum) is a medicinal plant considered antibacterial for its secondary metabolites.Purpose: This study aims to determine the antibacterial effect of red ginger (Zingiber officinale var. rubrum) ethanol extract against Streptococcus epidermidis using a non-equivalent control group design study.Method: Red ginger (Zingiber officinale var. rubrum) ethanol extract was made with the maceration method. This study uses a microdilution test on 96 well plates. The absorbance value was read using a spectrophotometer to determine the Minimum Inhibitory Concentration (MIC) value, and streaking agar was used to find the Minimum Bactericidal Concentration (MBC) value.Result: The result shows that the red ginger (Zingiber officinale var. rubrum) ethanol extract at a concentration of 62,5 μg/mL inhibits 75% of bacteria growth, at 125 μg/mL inhibits 60% of bacteria growth, at 250 μg/mL inhibits 45% of bacteria growth, at 500μg/mL inhibits 65% of bacteria growth and at 1.000μg/mL inhibits 50% of bacteria growth. The streaking agar test result shows bacteria growth on every concentration.Conclusion: Red ginger (Zingiber officinale var. rubrum) ethanol extract in the concentration range of 62,5-1.000 μg/mL have no MIC and MBC value against Staphylococcus epidermidis. 
Investigation of Noise Induced Hearing Loss at Shipyard Company, Surabaya Yudhiakuari Sincihu; Steven Steven; Mulya Dinata; Melani Taurusia
The Indonesian Journal of Occupational Safety and Health Vol. 8 No. 3 (2019): The Indonesian Journal of Occupational Safety and Health
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (891.675 KB) | DOI: 10.20473/ijosh.v8i3.2019.321-327

Abstract

Introduction: Noise is a health risk that cannot be avoided in production process. Noise has the potential to cause hearing loss for workers. The bad news, noise damage due to noise is permanent. Audiometric screening at shipyard company employees found 81.2% experienced Sensory-Neural Hearing Loss. 61.5% of employees experience deafness in both ears. The research objective was to find the cause of deafness at shipyard company. Methods: A Quantitative research with cross sectional approach in 64 subjects who worked in the ship repair production unit. The sample is chosen with a simple random technique according to inclusion and exclusion criteria. Assessment was carried out using questionnaires, measurement, and direct observations. Result: The bad habit of wearing ear protectors on employees as a cause of deafness (p<.001, Coef .517**). Sound level measurement shows the activity of chipping, welding, cutting and outfitting with noise intensity more than the recommended threshold (85 dBA for 8 hour per day). Noisy sources were found such as blowers, compressors, grinders, cutting mach ines, ringlet machines, hammer blows on plates and generators. Conclusion: Hearing loss in shipyard company employees is a work-related disease caused by the poor culture of wearing ear protectors. The habits does not wear earplug/earmuff tools because its not comfortable in the ear when the appliance is used, the tools too small so its easily lost, forgetten to carry, and tool are not available.
Co-Authors Budianto, Andrea Dewi, Dewa AL Isbandiati, Endang Melani Taurusia Steven, . Tanuy, Ricky S Yudhiakuari Sincihu