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All Journal Window of Health : Jurnal Kesehatan Unnes Journal of Public Health Journal of Borneo Holistic Health
Purnamasari, Feby
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Religion Humanities Health Professions Medicine & Pharmacology Nursing Public Health

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Effectiveness of Soursop Leaf Extract (Annona muricata l.) on IL-6 Levels in Mammary Sprague dawley Female Rats Induced by Staphylococcus aureus Purnamasari, Feby; Yulianty, Risfah; Latief, Syamsa
Unnes Journal of Public Health Articles in Press
Publisher : Universitas Negeri Semarang in cooperation with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ujph.v0i0.30904

Abstract

  Research this aiming for analyze effectiveness extract leaf soursop could take effect to IL-6 levels at mammae rat female Sprague Dawley induced Staphylococcus aureus. Research this use type research Experiment Moot or quasi-experimental design with the design of the Post-test Only Control Group Design by looking at the 3th and 6th day IL-6 levels after induction bacteria Staphylococcus aureus and giving treatment on mammae rat female Sprague Dawley. Taking sample blood done at eye rat 2 times with examination elisa kit. Data analyzed with use Hock and Post test followed by the Mann Whitney test . Research results to show that not there is difference IL-6 levels at group control (?=0,062 > ? =0,05) and group antibiotics (?=0,0514 > ? =0,05). On group leaf soursop (?=0.037 < ? =0,05) and group antibiotics + leaves soursop and on group control (?=0.030 < ? =0,05) to show there is difference levels IL-6. Value mean on group soursop 7.50 ± 1.74 pg/ml day to3, and 7.50 ± 1.74 1 pg/ml day 6. Value mean on group soursop + antibiotics 7.46 ± 26t.66 pg/ml Day 3, and 4.73 ± 1.36 pg/ml day 6. The implication of this study is that soursop leaf extract or combination of antibiotic + soursop leaf extract can be as a complementary therapy for mastitis caused by the bacteria Staphylococcus aureus. Keywords: Extract Leaf Soursop, Levels IL-6, Rat Sprague Dawley Females
Identifikasi Senyawa Aktif dari Ekstrak Daun Sirsak (Annona muricata L.)dengan Perbandingan Beberapa Pelarut pada Metode Maserasi Purnamasari, Feby
Window of Health : Jurnal Kesehatan Vol 4 No 3 (Juli 2021 )
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33368/woh.v4i03.588

Abstract

Soursop (Annona muricata L) is one of the native tropical fruit plants used to treat headaches, hypertension, coughs, asthma, and sedatives. Of the many medicinal plants, soursop leaves are used traditionally to treat inflammation. This study aims to determine the content of active compounds contained in soursop leaf extract with several solvents in the maceration processThe extraction method used in this research is the maceration method using 70% ethanol as a solvent. The extract obtained is then evaporated using a rotary evaporator until thickened, then dried with the help of a water bath. The resulting viscous extract was put into a portion of porcelain and the extract was weighed. The phytochemical tests that were carried out were saponins, flavonoids, alkaloids, tannins and steroids. The results of this study from the test, it was known that the soursop leaf extract sample with positive methanol solvent contained several active compounds in the form of flavonoids, saponins, tannin alkaloids, and steroids. The conclusion of The implication of this research is soursop leaf extract with active compounds in the form of flavonoids, saponins, and tannins which have the ability as antibacterial, antioxidant, anti-inflammatory, and inhibit bacterial growth or even die, and are able to prevent cancer.Researchers concluded that the soursop (Annona muricata L.) leaf extract contains active compounds in the form of alkaloids, tannins, saponins, steroids, flavonoids. The bioactive compounds contained in the soursop leaf extract can inhibit the growth of pathogenic bacteria so that they can be used as complementary anti-inflammatory and antibacterial therapies.
GAMBARAN KEJADIAN HIPEREMESIS GRAVIDARUM DI BIDAN PRAKTEK MANDIRI ST. NILAWATI S.ST Purnamasari, Feby
Journal of Borneo Holistic Health Vol 3, No 2 (2020): Journal Of Borneo Holistic Health
Publisher : Fakultas Ilmu Kesehatan, Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/borticalth.v3i2.1672

Abstract

Penelitian ini bertujuan untuk mengetahui gambaran Kejadian Hiperemesis Gravidarum Berdasarkan Umur Ibu, Umur kehamilan Ibu, dan Gravida ibu di Bidan Praktek Mandiri ST. Nilawati S.ST. Penelitian ini adalah jenis penelitian survey dengan metode pendekatan deskriptif yang bermaksud memberikan gambaran tentang kejadian Hiperemesis Gravidarum pada ibu hamil. Pengambilan sampel dengan cara Non Random Sampel (Purposive Sampling) Adalah metode dengan menggunakan kriteria yang telah dipilih oleh peneliti dalam memilih. Kriteria yang ditentukan oleh peneliti yaitu ibu hamil dengan muntah yang terus menerus, nafsu makan yang berkurang, berat badan menurun. Data yang dikumpulkan berupa data sekunder yang diperoleh dengan mempelajari catatan atau laporan dan buku register di Bidan Praktek Mandiri ST.Nilawati S.ST. Data dianalisis dengan Analisis data yang dilakukan adalah analisis deskriptif dengan rumus dan Pengolahan data dilakukan secara manual dalam bentuk tabel frekuensi dan presentasi dengan penjelasan tabel dalam naskah atau narasi. Hasil penelitian menunjukkan bahwa adi kesimpulannya terdapat 51 (68%) kasus dengan kejadian hiperemesis gravidarum, yang berisiko tinggi berdasarkan umur ibu yaitu umur 20 - 35 tahun, lebih banyak terjadi pada gravida 1 dan 3, dan terjadi pada umur kehamilan 16 minggu.
Perbedaan Perawatan Tali Pusat Terbuka Dan Perawatan Tali Pusat Tertutup Dengan Efektifitas Pelepasan Tali Pusat Purnamasari, Feby
Journal of Borneo Holistic Health Vol 4, No 2 (2021): Journal Of Borneo Holistic Health
Publisher : Fakultas Ilmu Kesehatan, Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/borticalth.v4i2.2062

Abstract

Bayi memerlukan pemantauan ketat dan perawatan yang dapat meningkatkan kesempatan menjalani masa transisi yang baik terhadap kehidupannya di luar uterus. Salah satunya perawatan tali pusat. Tali pusat dapat merupakan pintu masuk bagi infeksi ke tubuh bayi.Tingginya angka kematian bayi antara lain disebabkan asfiksia, BBLR, infeksi tali pusat (Tetanus neonatorum), congenital, dan lain-lain. Tujuan dalam penelitian ini adalah untuk mengetahui adakah perbedaanantara perawatan tali pusat terbuka dan perawatan tali pusat tertutup tentang efektifitas pelepasan tali pusat di BPM Nila Pangkep.Penelitian ini metode eksperimenmenggunakan desain non equivalent time sampel design dengan pendekatan sampling systematis, penelitian ini memiliki jumlah responden 33 bayi dengan tekhnik pengambilan probability sampling. Data dalam penelitian ini didapat dengan melakukan pengamatan dan intervensi langsung pada setiap responden.Hasil penelitian dengananalisis data yang digunakan adalah Uji T (Indepedent samples test) dengan tingkat kemaknaan α = 0.05 jika p α 0.05 artinya terdapat pengaruh perawatan tali pusat terbuka dan perawatan tali pusat tertutup tentang efektifitas pelepasan tali pusat atau perawatan dengan teknik terbuka lebih cepat waktu pelepasan tali pusatnya dibandingkan dengan perawatan teknik tertutup.
Co-Authors Latief, Syamsa Risfah Yulianty