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Formulation of Antiacne Cream Dosage Form Containing Mangosteen (Garcinia mangostana L.) Pericarp Ethanolic Extract Supomo; Apriliana, Anita; Purnawati, Titin; Risqi, Ainur
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 1 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (860.169 KB) | DOI: 10.32734/idjpcr.v1i1.207

Abstract

Abstract. The aim of this study was to formulate ethanolic extract of mangosteen (Garcinia mangostana L.) pericarp (EEMP) in the antiacne cream dosage form. The formulae were made with 3 varied concentrations of 0.5%, 1.5% and 4.5%. The tests carried out in this study were organoleptic cream preparations (odor, color, texture), homogeneity, pH, determination of the type of cream, spreadability, and the antibacterial activity against Staphylococcus epidermidis. The results of physical property evaluations showed that the EEMP indicated the pH value of 6, the spredability of the cream increased along with the increasing length of storage time. Duncan Test on the measurement of diameter dispersibility based on storage time showed that there were significant differences between the spreadability of the cream B and C. The cream produced was easy to wash indicating oil in water (o/w) type. The results of antibacterial activity test applying agar diffusion method using Mueller Hinton medium Agar (MHA) indicated that the inhibition zones of formulae II and III were 5.2 and 6 mm, respectively. Whereas, the formula I as well as the negative control showed no inhibition zones. It can be concluded that the EEMP can be formulated as an antiacne cream. The best cream formula was the formula II with the results of physical properties test were quite stable and able to produce inhibition zone against Staphylococcus epidermidis. Keywords: Garcinia mangostana, cream, antiacne, antibacterial, Staphylococcus epidermidis.
Effort to Prevent COVID-19 STIKES Samarinda (STIKSAM) by Distributing Hand Sanitizer in Air Hitam Village of Samarinda City: Upaya Pencegahan COVID-19 STIKES Samarinda (STIKSAM) dengan Menyalurkan Hand Sanitizer di Kelurahan Air Hitam Kota Samarinda Syamsul, Eka Siswanto; Supomo; Ansyori, Achmad Kadri
Mattawang: Jurnal Pengabdian Masyarakat Vol. 2 No. 2 (2021)
Publisher : Yayasan Ahmar Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (604.338 KB) | DOI: 10.35877/454RI.mattawang338

Abstract

Due to the COVID-19 pandemic outbreak, the availability of handwashing products in Samarinda City has become a rare item. The purpose of this activity is to prevent COVID-19 through the use of Hand Sanitizer. This method in this service includes several stages, namely preparation that includes the preparation of tools and materials, the production process with the stages of mixing materials into hand sanitizer products, and the packaging process that is inserting the finished hand sanitizer into small bottles measuring 20 ml, 100 ml and Container 5 L, as well as labelling the brand hand sanitizer, and subsequently the distribution process in RT 27, 28 , 29 and 30 Black Water Village. Civitas Akademika STIKES Samarinda (STIKSAM) and Ikatan Keluarga Alumni (IKA STIKSAM) make hand sanitizer in accordance with WHO regulations, hand sanitizer distribution process in rt 27, RT 28, RT 29 and RT 30 Black Water Village and COVID-19 referral hospital (AW Hospital. Sjahranie and I.A. Moeis Hospital) went smoothly. Mayor of Samarinda H. Syaharie Ja'ang appreciated and reviewed the activities of Hand Sanitizer making at STIKES Samarinda campus. Abstrak Akibat wabah pandemi COVID-19 ketersediaan produk pencuci tangan di Kota Samarinda menjadi barang langka. Tujuan kegiatan ini yaitu melakukan upaya pencegahan COVID-19 melalui penggunaan Hand Sanitizer. Metode pada pengabdian ini meliputi beberapa tahap yaitu persiapan yang meliputi penyiapan alat dan bahan, proses produksi dengan tahapan pencampuran bahan-bahan menjadi produk hand sanitizer, dan proses pengemasan yaitu memasukan hand sanitizer yang sudah jadi ke dalam botol-botol kecil berukuran 20 ml, 100 ml maupun Dirigen 5 L, serta labelling merek hand sanitizer, dan selanjutnya proses pendistribusian di RT 27, 28, 29 dan 30 Kelurahan Air Hitam. Civitas Akademika STIKES Samarinda (STIKSAM) dan Ikatan Keluarga Alumni (IKA STIKSAM) membuat hand sanitizer sesuai ketentuan WHO, proses pendistribusian hand sanitizer di wilayah RT 27, RT 28, RT 29 dan RT 30 Kelurahan Air Hitam dan Rumah sakit rujukan COVID-19 (RSUD AW. Sjahranie dan RSUD I.A. Moeis) berjalan dengan lancar. WaliKota Samarinda H. Syaharie Ja’ang mengapresiasi dan meninjau kegiatan pembuatan Hand Sanitizer di kampus STIKES Samarinda.