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All Journal Jurnal Ilmiah Manuntung Indonesian Journal of Pharmaceutical and Clinical Research

Anita Apriliana, Anita

Akademi Farmasi Samarinda

Author-ID : 565047

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Articles

IDENTIFIKASI SENYAWA METABOLIT SEKUNDER DAN UJI AKTIVITAS EKSTRAK ETANOL HERBA MENIRAN (Phyllanthus niruri L.) TERHADAP CANDIDA ALBICANS MENGGUNAKAN METODE DIFUSI CAKRAM Apriliana, Anita; Kusumawati, Eko; Selvitawati, Selvitawati
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

The aim of this research is to know the ability of meniran ethanol extract (Phyllanthus niruri L.) in inhibiting the growth of Candida albicans. The research design is an experimental study. The extract used was herbal meniran extract made by maceration using 70% ethanol solvent, the content of ethanol extract of meniran tested against Candida albicans using disc diffusion method were 5%, 10%, 20%, 30% and 40%. Activity test conducted on Sabaraound Dextrose agar media that has been smeared with Candida albicans culture which has been standardized with Mc Farland standard. The pre-tested disc paper is first dipped into the extract with various concentrations. Incubated at 30 Â° C for 24 hours and the inhibit zone formed was measured. The result showed that herbal ethanol extract of meniran resulted in drag zone diameter at Candida albicans ie 8,5 mm; 10.3 mm; 12.6 mm; 14.1 mm and 14.3 mm, for negative control 0 mm and positive control 20.1 mm. Data obtained from the results of the study were analyzed using one way anova method showed p - value <0,05, it was concluded that there was significant difference between negative control, 5%, 10%, 20%, 30%, 40% and positive control.

FORMULA DAN EVALUASI GEL PEMBERSIH TANGAN EKSTRAK BAWANG TIWAI (Eleutherine bulbosa (Mill.) Urb) Sukawaty, Yullia; Apriliana, Anita; Warnida, Husnul
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Bawang tiwai (Eleutherine bulbosa (Mill.) Urb.) acts as an antibacterial because it contains a class of alkaloids, flavonoids, saponins, tannins, glycosides, triterpinoida / steroid, anthraquinone glycosides.Bawang tiwai onions can be used as an antibacterial active ingredient formulated in a gel hand sanitizer. The purpose of this study to determine the effect of varying concentrations of alcohol on the physical properties of gel preparation and inhibition of E.coli bacteria which are formulated in the form of a gel hand sanitizer bawang tiwai extract. Research conducted on fomula gel hand sanitizer bawang tiwai extract with various concentrations of alcohol F1 0%, F2 10%, F3 20%, F4 60% include (organoleptic, homogeneity, pH, dispersive power, consistency and viscosity) and continued with test inhibition of E. coli using disc diffusion method (Kirby-Bauer) in F1 0%, 10% F2, F3 20%, K (-) 60% and K (+) Triclosan 0.1%. Data were analyzed with SPSS 16.0 using Kruskal Wallis test with a level of 95%, Î± = 0.05. Gel hand sanitizer contains bawang tiwai extract 20% meets the requirements of the physical stability and have antibacterial inhibition of E. Coli

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KEREHAU (Callicarpa longifolia Lam) TERHADAP Escherichia coli dan Staphylococcus aureus Kusumawati, Eko; Apriliana, Anita; Khatimah, Khusnul
Jurnal Ilmiah Manuntung Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Kerehau (Callicarpa longifolia Lam) is a plant that has traditionally efficacious as a cure colds and diarrhea. Part used as medicine are the leaves. This study aims to determine the antibacterial activity of ethanol extract of leaves kerehau on Escherichia coli and Staphylococcus aureus. Kerehau leaf extract prepared by maceration method using ethanol 70%, with a test concentration of 10%, 25%, 50%, and 100% and chloramphenicol 0.1% (w / v) as a positive control and dimethyl sulfoxide 1% (v / v) as a negative control. The results of antibacterial activity test with extract concentrations of 25%, 50% and 100% in Escherichia coli is 9.45 mm, 12.21 mm and 17.38 mm, for the positive control is 21.85 mm. The results of antibacterial activity test with extract concentrations of 10%, 25%, 50% and 100% in Staphylococcus aureus was 7.3 mm, 9.85 mm, 13.65 mm and 20.58 mm, for the positive control was 24.05 mm. The antibacterial activity was analyzed by One Way ANOVA showed significant differences between treatments

INVENTARISASI DAN IDENTIFIKASI TUMBUHAN OBAT SUB ETNIS KUTAI DESA GENTING TANAH KECAMATAN KEMBANG JANGGUT KABUPATEN KUTAI KARTANEGARA KALIMANTAN TIMUR Apriliana, Anita; Hendra, Medi; Sapitri, Atila
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Indonesia has rich tropical forests will be diverse plants that can be used as a traditional medicine, ranging from roots, stems, leaves, until all fruit is of great value and can be used as a medicine for the health as well as from different tribe who were in Indonesia. Since old time sub etnic Kutai using different types of plants as a medicine because the lack of medical personnel and health care center in curing diseases. This study aims to find out the types of medicinal herbs used by tribes. The results there were 39 Medicinal plants used by tribes that isÂ Serai, Sirih, Tumbuh daging, Kepius, Patah tulang, Kunyit root, Senuru , Mali wood, Prepat wood, lupun root, Kecubung, Terung pipit, Gelinggang, Beribit grass, Syurga leaf, Tapis bongol, Nyiur ongo, Singgah bini wood, Penggel habeng, Serkemudi grass, Tunjuk langit root, Kemet hitam, Pacar beleng, penggel putih, Ketotol grass, Kemantrah, Sahung wood, Tajerebo, Cula adem, Risip leaf, Lalang, Sampai root, Cancut haji jewa, Mersesat leaf, Lekop leaf, Kuku tupai, Kempis root, Kemet putih and Kedeme

Formulation of Antiacne Cream Dosage Form Containing Mangosteen (Garcinia mangostana L.) Pericarp Ethanolic Extract Supomo; Apriliana, Anita; Purnawati, Titin; Risqi, Ainur
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 1 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Abstract. The aim of this study was to formulate ethanolic extract of mangosteen (Garcinia mangostana L.) pericarp (EEMP) in the antiacne cream dosage form. The formulae were made with 3 varied concentrations of 0.5%, 1.5% and 4.5%. The tests carried out in this study were organoleptic cream preparations (odor, color, texture), homogeneity, pH, determination of the type of cream, spreadability, and the antibacterial activity against Staphylococcus epidermidis. The results of physical property evaluations showed that the EEMP indicated the pH value of 6, the spredability of the cream increased along with the increasing length of storage time. Duncan Test on the measurement of diameter dispersibility based on storage time showed that there were significant differences between the spreadability of the cream B and C. The cream produced was easy to wash indicating oil in water (o/w) type. The results of antibacterial activity test applying agar diffusion method using Mueller Hinton medium Agar (MHA) indicated that the inhibition zones of formulae II and III were 5.2 and 6 mm, respectively. Whereas, the formula I as well as the negative control showed no inhibition zones. It can be concluded that the EEMP can be formulated as an antiacne cream. The best cream formula was the formula II with the results of physical properties test were quite stable and able to produce inhibition zone against Staphylococcus epidermidis. Keywords: Garcinia mangostana, cream, antiacne, antibacterial, Staphylococcus epidermidis.

Co-Authors Khatimah, Khusnul Kusumawati, Eko Medi Hendra, Medi Purnawati, Titin Risqi, Ainur Sapitri, Atila Selvitawati, Selvitawati Sukawaty, Yullia Sukawaty, Yullia Supomo Warnida, Husnul Warnida, Husnul

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