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All Journal Jurnal Aisyah : Jurnal Ilmu Kesehatan
Koibuchi, Noriyuki
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Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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The association of serum 25-hydroxyvitamin D and Alzheimer’s Disease: a meta-analysis Putri, Siti Sarahdeaz Fazzaura; Irfannuddin, Irfannuddin; Murti, Krisna; Kesuma, Yudianita; Koibuchi, Noriyuki
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (738.923 KB) | DOI: 10.30604/jika.v8i2.1769

Abstract

Serum 25-hydroxyvitamin D deficiency has been suggested as a promising prognostic factor for dementia. Meta-analysis published revealed statistically significant differences of 25-hydroxyvitamin D levels in patients with Alzheimer's disease (AD) but other studies have been published since then.The purpose of present study was to quantify the association of serum 25-hydroxyvitamin D and AD. Literature search was performed from inception up to November 22 using Pubmed database. Based on the pooled analysis, patients with Alzheimer’s disease tend to have a vitamin D deficiency relative to patients with normal cognitive function. These results strongly support the involvement of vitamin D as a critical disease-modifying variable in the reduction of AD symptoms.
Co-Authors Irfannuddin Irfannuddin Krisna Murti Putri, Sarahdeaz Siti Fazzaura Yudianita Kesuma, Yudianita