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META ANALYSIS: EFFICACY OF SHORT TERM WEIGHT-LOSS MAINTENANCE WITH FINANCIAL INCENTIVES INTERVENTION Siti Fazzaura Putri Sarahdeaz; Ardesy Melizah Kurniati; Fiona Widyasari; Karolin Adhisty; Ari Martino; Rifani Akbar Sulbahri; Yuni Adinda Putri
Jambura Journal of Health Sciences and Research Vol 4, No 2 (2022): Jambura Journal of Health Sciences and Research
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v4i2.13932

Obesitas telah menjadi penyebab utama meningkatnya penyakit tidak menular. Penggunaan insentif finansial (FI) sangat mendorong gaya hidup sehat. Pola intervensi ini digunakan untuk mendorong perilaku hidup sehat yang bertujuan untuk mencegah dan mengelola penyakit kronis. Kebaruan penelitian ini yaitu meneliti secara meta analisis tentang kemanjuran pemeliharaan penurunan berat badan jangka pendek dengan intervensi insentif keuangan. Tujuan dari penelitian ini adalah untuk mengkonfirmasi perbedaan hasil antara studi, penelitian ini dilakukan untuk menguji efek keseluruhan dari studi menggunakan intervensi FI pada program penurunan berat badan. Metode yang digunakan adalah Database PubMed untuk mencari data. Data diambil dari studi yang melaporkan perubahan intervensi FI dengan hasil perubahan berat badan. Hasilnya menemukan bahwa 4 studi dengan obesitas dimasukkan. Hasil gabungan menunjukkan bahwa FI berpengaruh signifikan terhadap perubahan berat badan. Terdapat perbedaan peningkatan berat badan yang signifikan pada kelompok intervensi FI dibandingkan dengan kelompok kontrol (SMD: -3,37; CI 95%). Heterogenitas statistik ditemukan (I2 = 99,92%, P = 0,00). Kesimpulan hasil belum menunjukkan efek menguntungkan dari FI jangka pendek selama 3 bulan pada penurunan berat badan pada pasien obesitas. Namun, heterogenitas statistik ditemukan sehingga analisis subkelompok diperlukan.Kata kunci: penurunan berat badan; obesitas; insentif finansial. AbstractObesity has become a major etiology of the increase in non-communicable diseases. The use of financial incentives (FI) has greatly encouraged a healthy lifestyle. This intervention pattern is used to encourage healthy lifestyle behaviors aimed at preventing and managing chronic diseases. The novelty of this study is to examine the meta-analysis of the efficacy of maintaining short-term weight loss with financial incentive interventions. The aim of this study was to confirm differences in results between studies, this study was conducted to examine the overall effect of studies using FI interventions on weight loss programs. The method used is the PubMed Database to search for data. Data were drawn from studies reporting changes in the FI intervention with outcome changes in body weight. The results found that 4 studies with obesity were included. The combined results show that FI has a significant effect on changes in body weight. There was a significant difference in weight gain in the FI intervention group compared to the control group (SMD: -3.37; 95% CI). Statistical heterogeneity was found (I2 = 99.92%, P = 0.00). Conclusion the results have not shown a beneficial effect of short-term FI for 3 months on weight loss in obese patients. However, statistical heterogeneity was found so that a subgroup analysis was needed.

ONLINE HEALTH CONSULTATION PLATFORM DURING THE COVID-19 PANDEMIC Budi Santoso; Siti Fazzaura Putri Sarahdeaz; Hertanti Indah Lestari; Yudhie Tanta
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (348.735 KB)

Indonesia is currently experiencing the second wave of the Covid-19 pandemic. The Coronavirus is currently spreading faster with a higher severity, causing an increase in Covid-19 cases in the UNSRI Medical Faculty. There were 73 students and 13 lecturers and/or educators who were confirmed to have Covid-19 as of July 14, 2021, who had been recorded since early July. The increase in the number of confirmed cases of Covid-19 in students and lecturers causes the teaching and learning process to be suboptimal. . In addition, the increasing number of Covid-19 in the community while access to hospitalization is reduced, causing many people to need to self-isolate at home, who need a consultation about their health.The need for online health services is currently increasing as well where the Covid-19 number is currently at its peak. Many people need self-isolation at home because hospitals lack treatment facilities. Online health services are needed by people who find it difficult to consult directly with health facilities.The Faculty of Medicine, Sriwijaya University (FK Unsri), especially the lecturers who are also health workers, initiated the formation of the Online Doctor Chat (CDO), as a response to the Covid-19 pandemic situation

Penyuluhan pentingnya pengukuran status gizi dalam upaya pencegahan stunting Medina Athiah; Ardesy Melizah Kurniati; Siti Fazzaura Putri Sarahdeaz; Rima Zanaria; Syarif Husin; Hertanti Indah Lestari; Heni Yusnita; Putri Maya Sari; Sisca Yulistiana
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 3 No 2 (2022): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V3I1.79

Reducing the incidence of stunting is one of the goals of the 2025 Global Nutrition Targets. The prevalence of stunting in children in Indonesia is still high over the last decade. Lack of knowledge on nutritional intake, maternal nutritional status factors, breastfeeding practices, complementary feeding practices, and exposure to infections as well as other factors including education, food system, health care, and sanitation are important determinants of child stunting in Indonesia. This community service activity is carried out with the aim of providing counseling about stunting to mothers and measuring the nutritional status of toddlers as an effort to prevent stunting. The activity was coordinated by students who are members of the Student Executive Board of the Faculty of Medicine, Sriwijaya University (FK Unsri) and Muhammadiyah University (FK UM), involving FK Unsri lecturers, in collaboration with staff at the Puskesmas Taman Bacaan Palembang. At the end of the activity, participants became more aware of the importance of measuring children's nutritional status and stunting prevention measures. There were 6 toddlers who were indicated to be malnourished and reported for management by the Puskesmas team so that they did not progress to stunting.

EDUKASI PENANGGULANGAN DAMPAK PEMBELAJARAN DARING TERHADAP KESEHATAN REMAJA SELAMA PANDEMI COVID-19 Arwan Bin Laeto; Budi Santoso; Siti Sarahdeaz Fazzaura Putri; Syifa Alkaf
Lontara Abdimas : Jurnal Pengabdian Kepada Masyarakat Vol 3 No 2 (2022): Desember
Publisher : Lembaga Penelitian Dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lomas.v3i2.301

Health is an important thing that needs to be maintained at all times. The COVID-19 pandemic that has hit the world, including Indonesia, has had a significant impact on the health and social life of teenagers. The social impact experienced by adolescents is in the aspect of education which requires adolescents to take part in online learning. The online learning that teenagers go through has an influence on the health of their bodies. Health complaints experienced by adolescents during online learning include backache, disturbed sleep, eye fatigue and weight gain. Seeing this situation, this community service activity was carried out. This activity involves youth participants and is carried out using educational and demonstration methods. The education provided discussed the impact of online learning during the covid-19 pandemic, the concept of body fitness and forms of exercise in an effort to overcome the impact of online learning. The results obtained indicate that through education, there is an increase in participants' understanding of the various impacts received by adolescents during online learning. In addition, adolescent knowledge related to the concept of fitness and efforts to maintain fitness through exercise has also increased. The sports demonstration provided succeeded in opening the participants' insight that sports can still be done during the covid-19 pandemic, through technology media, both independently and in groups. So it can be concluded that sport is the best effort in overcoming the impact of online learning on adolescent health during the covid-19 pandemic.

Effects of Fluoride Exposure During Pregnancy in Mice Brain Neurogenesis (Mus musculus) Siti Sarahdeaz Fazzaura Putri; Irfannuddin Irfannuddin; Krisna Murti; Yudianita Kesuma; Hardi Darmawan; Noriyuki Koibuchi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.720

Background: Fluoride is a type of micromineral found in teeth and bones. This mineral is also found in nature, such as in soil, water, plants, rocks, and even air. Fluoride can cross the placental barrier and diffuse into the cord blood, with a range from 60% to 91% of maternal fluoride. Maternal fluoride exposure during pregnancy and lactation can affect learning ability, memory, and expression of glutamate receptors. This study aimed to determine the effect of fluoride exposure during pregnancy and lactation on brain neurogenesis in vivo. Methods: In vivo, experimental study using mice (Mus musculus) C57BL/6 as many as 60 brood mice (20 males and 40 females) and as many as 30 offspring mice. Mice broodstock were first mated to produce offspring. During pregnancy, the female mice were exposed to fluoride (NaF). Exposure of broodstock mice to NaF was divided into 0 mg/L, 50 mg/L, 100 mg/L, and 150 mg/L exposure groups. Expression of PSD-95 protein was carried out by immunohistochemical examination of mouse brain tissue. Data analysis was carried out with the help of SPSS using univariate and bivariate methods. Results: There was a decrease in the expression of PSD-95 with increasing exposure to NaF doses during pregnancy and lactation. Giving NaF at a dose of 50 mg/L did not decrease PSD-95 expression because the results were not different from the control. In contrast, the administration of NaF doses that can reduce the expression of PSD-95 are doses of 100 and 150 mg/L. Conclusion: Fluoride exposure during pregnancy contributed to a decrease in mice brain neurogenesis, as indicated by the expression of the PSD-95 protein in the hippocampus area.

Effects of Fluoride Exposure During Pregnancy in Mice Brain Neurogenesis (Mus musculus) Siti Sarahdeaz Fazzaura Putri; Irfannuddin Irfannuddin; Krisna Murti; Yudianita Kesuma; Hardi Darmawan; Noriyuki Koibuchi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.720

Background: Fluoride is a type of micromineral found in teeth and bones. This mineral is also found in nature, such as in soil, water, plants, rocks, and even air. Fluoride can cross the placental barrier and diffuse into the cord blood, with a range from 60% to 91% of maternal fluoride. Maternal fluoride exposure during pregnancy and lactation can affect learning ability, memory, and expression of glutamate receptors. This study aimed to determine the effect of fluoride exposure during pregnancy and lactation on brain neurogenesis in vivo. Methods: In vivo, experimental study using mice (Mus musculus) C57BL/6 as many as 60 brood mice (20 males and 40 females) and as many as 30 offspring mice. Mice broodstock were first mated to produce offspring. During pregnancy, the female mice were exposed to fluoride (NaF). Exposure of broodstock mice to NaF was divided into 0 mg/L, 50 mg/L, 100 mg/L, and 150 mg/L exposure groups. Expression of PSD-95 protein was carried out by immunohistochemical examination of mouse brain tissue. Data analysis was carried out with the help of SPSS using univariate and bivariate methods. Results: There was a decrease in the expression of PSD-95 with increasing exposure to NaF doses during pregnancy and lactation. Giving NaF at a dose of 50 mg/L did not decrease PSD-95 expression because the results were not different from the control. In contrast, the administration of NaF doses that can reduce the expression of PSD-95 are doses of 100 and 150 mg/L. Conclusion: Fluoride exposure during pregnancy contributed to a decrease in mice brain neurogenesis, as indicated by the expression of the PSD-95 protein in the hippocampus area.

POTENSI MIKROBIOTA USUS DALAM PENCEGAHAN DAN TATALAKSANA OBESITAS Putri, Sarahdeaz Siti Fazzaura; Irfanuddin, Irfanuddin; Murti, Krisna
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 3 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.597 KB)

Obesitas adalah epidemi yang berkembang di banyak negara, termasuk di negara-negara berkembang. Obesitas memiliki dampak kesehatan yang serius termasuk penyakit kardiovaskular, hipertensi pulmonal, gangguan muskuloskeletal, berbagai jenis kanker, bahkan kematian. Biaya sosial dan ekonomi dari obesitas dan komorbiditas terkaitnya sangat besar dan membebani sistem perawatan kesehatan. Proses fisiologis yang mengatur berat badan dan metabolisme menjadi penyebab perjalanan peyakit obesitas, termasuk sinyal lapar dan kenyang yang berasal dari perifer dan respon gastrointestinal terintegrasi yang dipengaruhi oleh mikrobiota usus. Mikrobiota berperan dalam perjalanan penyakt obesitas dengan mememngaruhi perolehan nutrisi, regulasi energi, dan memiliki peran penting dalam mengatur berat badan. Komposisi mikrobiota usus terbentuk dalam tahun pertama kehidupan dan terus mengalamin perubahan ke mikrobiota tipe dewasa yang diakibatkan oleh faktor inang dan faktor eksternal, termasuk efek dari mikrobiota itu sendiri, perubahan perkembangan di lingkungan usus, dan transisi ke diet orang dewasa. Triliunan bakteri yang berada di dalam saluran pencernaan manusia meningkatkan kemungkinan bahwa mikrobiota usus memiliki peran penting dalam mengatur berat badan dan mungkin ikut bertanggung jawab atas perkembangan obesitas pada beberapa orang. Artikel ini membahas peran memodifikasi mikrobiota usus dalam perjalanan penyakit dan perkembangan obesitas.

Hubungan Kualitas Tidur Remaja Selama Pandemi Covid-19 dengan Aktivitas Fisik Serta Screen-Time Arwan Bin Laeto; Siti Sarahdeaz Fazzaura Putri; Eka Febri Zulissetiana; Swanny
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19226

Abstract. Public health is an aspect that has shown a decline sincethe COVID-19 pandemic emerged, both globally and in Indonesia.Seeing these conditions, the Indonesian government has implemented restrictions on community mobility, including the learning process (lectures) which must be held online. This triggers an increasein screen time among teenagers, while at the same time there is adecrease in sleep quality and low physical activity. The purpose ofthis study was to determine the relationship between sleep qualityduring the COVID-19 pandemic with the level of physical activity andthe degree of screen time for adolescents. The objection of thisresearch is to analyze the relationship between adolescent sleepquality during the Covid-19 pandemic with levels of physical activityand screen-time. Methods: The study used an observationalapproach with a crosssectional design of 185 students. The researchwas conducted in November 2021 at the Faculty of Medicine,Sriwijaya University. Research data collection through onlinequestionnaires and data analysis using Chi square test. Results: Thisstudy shows the results, as many as 77.82% of students have poorsleep quality, 48.64% have low levels of physical activity and 76.22%of students show high smartphone screen-time. The bivariate testshowed that there was a significant relationship between the levelof physical activity and sleep quality, namely p = 0.002. However,there was no significant relationship between sleep quality and thedegree of screen-time (p = 0.253). Conclusion: The level of physicalactivity has a significant relationship with adolescent sleep quality.Physical activity is a factor that affects teenagers in getting goodquality sleep during the COVID-19 pandemic.

Studi Meta-Analisis: Hubungan antara Defisiensi Vitamin D dan Penyakit Parkinson Siti Sarahdeaz Fazzaura Putri; Irfannuddin Irfannuddin; Krisna Murti; Yudianita Kesuma; Noriyuki Koibuchi
Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Vol 9, No 1 (2023): JMK Yayasan RS.Dr.Soetomo, April 2023
Publisher : STIKES Yayasan RS.Dr.Soetomo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29241/jmk.v9i1.1430

Beberapa penelitian telah dilakukan untuk mengevaluasi kadar 25(OH)D pada pasien penyakit Parkinson. Namun, hasil penelitian ini tidak konsisten. Penelitian ini melakukan meta-analisis terhadap kadar 25(OH)D pada pasien dengan penyakit Parkinson. Database PubMed digunakan untuk melakukan pencarian literatur secara sistematis. Meta-analisis dilakukan dengan menggunakan model efek acak untuk menghitung perkiraan efek gabungan. Tujuh belas artikel dimasukkan dalam penelitian ini. Meta-analisis mengungkapkan bahwa pasien dengan penyakit Parkinson memiliki kadar 25(OH)D yang lebih rendah dibandingkan dengan kontrol. Temuan dari artikel prospektif dan retrospektif sebagian besar konsisten. Besarnya respon nocebo dalam uji coba terkontrol acak yang dirancang paralel pada penyakit Parkinson sangat penting dan harus dipertimbangkan dalam interpretasi hasil keamanan dan dalam desain dan interpretasi uji klinis masa depan.

The association of serum 25-hydroxyvitamin D and Alzheimer’s Disease: a meta-analysis Putri, Siti Sarahdeaz Fazzaura; Irfannuddin, Irfannuddin; Murti, Krisna; Kesuma, Yudianita; Koibuchi, Noriyuki
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

Serum 25-hydroxyvitamin D deficiency has been suggested as a promising prognostic factor for dementia. Meta-analysis published revealed statistically significant differences of 25-hydroxyvitamin D levels in patients with Alzheimer's disease (AD) but other studies have been published since then.The purpose of present study was to quantify the association of serum 25-hydroxyvitamin D and AD. Literature search was performed from inception up to November 22 using Pubmed database. Based on the pooled analysis, patients with Alzheimer’s disease tend to have a vitamin D deficiency relative to patients with normal cognitive function. These results strongly support the involvement of vitamin D as a critical disease-modifying variable in the reduction of AD symptoms.

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