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All Journal Riau Journal of Empowerment Jurnal Pengabdian Masyarakat Teknik Narra J Heca Journal of Applied Sciences
Puspita, Kana
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Edukasi Sadar Sampah dan Lingkungan dalam Rangka Pencegahan Penyebaran Covid-19 di Lokasi Wisata Ulee Lheue Fadlia, Faradilla; Izzaty, Nur; Puspita, Kana; Zalikha, Siti Nur
Riau Journal of Empowerment Vol 7 No 1 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/raje.7.1.32-49

Abstract

Ulee Lheue Beach is one of the marine tourism sites in Banda Aceh. Its appearance, apart from attracting visitors to enjoy the beauty of the shore, also has consequences for piles of garbage thrown carelessly by the visitors to the shoreline which has an impact on environmental damage. In addition, the visitors tend to heed the government’s appeal to strictly commit to health protocols such as social distancing, gathering prohibition, and wearing masks while they visit the tourism spots. Therefore, this community outreach sought to map the knowledge of the tourists about waste and its impact on tourism sites and its relation to the dangers of Covid-19. This service employed mixed methods (quantitative and qualitative). The survey results showed that the visitors have fairly good knowledge regarding the dangers of waste and Covid-19 yet still uninternalized in their daily attitudes. Thus, the service team provides education through leaflets and videos on Youtube channels, hoping that the visitors would have higher commitment towards the environmental hygiene and health protocols at tourist sites.
Implementasi Business Model Canvas (BMC) untuk Meningkatkan Pengelolaan Bisnis Produk Serbuk Cangkang Tiram di Desa Alue Naga Kota Banda Aceh Izzaty, Nur; Puspita, Kana; Fadlia, Faradilla
Jurnal Pengabdian Masyarakat Teknik Vol 5, No 2 (2023): Jurnal Pengabdian Masyarakat Teknik (JPMT)
Publisher : Fakultas Teknik Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/jpmt.5.2.76-82

Abstract

Rumoh Produksi Tiram di Desa Alue Naga, Banda Aceh, dengan didampingi oleh CV. Natural Aceh telah menjual ragam olahan produk dari tiram seperti kerupuk dan nugget tiram. Hasil pengolahan tiram meninggalkan limbah berupa cangkang tiram yang menjadi tumpukan sampah dan berdampak buruk pada lingkungan baik di darat maupun di perairan. Kelompok produksi tiram tersebut telah melakukan diversifikasi produk lebih lanjut untuk mengolah limbah cangkang tiram menjadi serbuk yang mengandung CaCO₃ dan bermanfaat sebagai adsorben serta dapat menjadi bahan baku pembuatan obat antisida. Produk tersebut bernilai komersil dan dapat dipasarkan namun masih terkendala dalam menentukan model bisnis. Oleh karena itu, pengabdian ini membantu memetakan model bisnis produk serbuk cangkang tiram dengan menggunakan Business Model Canvas (BMC). Target utama yang dicapai dari kegiatan pengabdian ini adalah adanya peta model bisnis produk serbuk cangkang tiram sehingga dapat menjadi konsep dan kerangka kerja acuan yang akan memudahkan pihak terkait dalam menjalankan bisnis produk serbuk cangkang tiram. Secara berkelanjutan, diversifikasi produk serbuk dari limbah cangkang tiram ini diharapkan dapat meningkatkan pendapatan masyarakat dan juga mengurangi dampak kerusakan lingkungan.
Optimization of Starch—κ-Carrageenan Hybrid Film as Drug Delivery System Using Response Surface Method Nisah, Khairun; Fahrina, Afrilia; Rizki, Diva Rayyan; Puspita, Kana
Heca Journal of Applied Sciences Vol. 1 No. 1 (2023): June 2023
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/hjas.v1i1.10

Abstract

Development of drug delivery systems (DDS) has been widely carried out using safe biopolymers – starch and κ-carrageenan. However, for optimal use, the foregoing polymers still suffers from mechanical weakness. Combining both polymers could enhance the properties of each of the polymer. This research aimed of improving the applicability of starch and κ-carrageenan as DDS by means of polyelectrolyte complexation to form a polymer film. The composition ratio of starch:κ-carrageenan was optimized using response surface method (RSM) on Design Expert 11.0 based on water swelling, tensile strength, and disintegration time of the film. Fourier transform infrared spectrometry was performed on the prepared starch—κ-carrageenan film and suggested the successful film preparation. The bulk characteristics of the film are dependent on the starch or κ-carrageenan composition ratio, where starch has been associated with higher thickness, while κ-carrageenan — rigidity. From the RSM, the optimized composition was revealed to be 2.95 and 2.84 g for starch and κ-carrageenan, respectively, in a 60 mL aqueous solvent. The predicted optimum properties of the film were 160.21%, 3.26 MPa, and 17.47 min for swelling degree, tensile strength, and disintegration time, respectively. Taken altogether, the characteristics of starch or κ-carrageenan individually could be modified by polymeric combination, where they could be optimized by means of RSM.
Molecular docking of two cytotoxic compounds from Calotropis gigantea leaves against therapeutic molecular target of pancreatic cancer Purnama, Agnia; Mardina, Vivi; Puspita, Kana; Qanita, Intan; Rizki, Diva R.; Hasballah, Kartini; Iqbal, Mudassar; Sarong, Murniana
Narra J Vol. 1 No. 2 (2021): August 2021
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narraj.v1i2.37

Abstract

The utilization of natural compounds as therapeutic agents to treat pancreatic cancer has recently focused on natural drug research. Calotropis gigantea has long been believed to be a medicinal plant that helps in treating various diseases. The bioactive compounds 9-metoxipinoresinol and isoliquiritigenin isolated from C. gigantea leaves are proven to act as therapeutic agents by inhibiting the cancer cell growth of Panc-1 cells. This study aimed to screen the potential molecular inhibition mechanisms of 9-metoxipinoresinol and isoliquiritigenin against pancreatic cancer development in-silico. We analyzed the activity of the aforementioned two compounds as inhibitors of several proteins that play a role in the growth of pancreatic cancer cells, such as GCNT3, GOT1, c-Met, PPARγ, BUB1, and NF-κβ, through molecular docking investigation. Our data suggested that 9-metoxipinoresinol and isoliquiritigenin were able to have well interaction with the target proteins, in which the predicted affinity energy ranged between -6.8 and 8.7 kcal/mol. The docking scores of 9-metoxipinoresinol and isoliquiritigenin were higher than the standard drug used (gemcitabine). Based on the binding affinity energy, GCNT3 and BUB1 are potentially to be used as target molecules for cancer therapy using 9-metoxipinoresinol and isoliquiritigenin, respectively.
Co-Authors Fadlia, Faradilla Fahrina, Afrilia Iqbal, Mudassar Izzaty, Nur Kartini Hasballah Khairun Nisah Mardina, Vivi Purnama, Agnia Qanita, Intan Rizki, Diva R. Rizki, Diva Rayyan Sarong, Murniana Siti Nur Zalikha