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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia eJournal Kedokteran Indonesia
Fify Henrika
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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DIAGNOSIS LABORATORIUM MALARIA Weny Rinawati; Fify Henrika
Majalah Kedokteran Indonesia Vol 69 No 10 (2019): Journal of the Indonesian Medical Association Majalah Kedokteran Indonesia Volu
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/jinma.v69i10.183

Abstract

Pendahuluan: Malaria adalah penyakit tropik yang disebabkan oleh parasit dan ditularkan melalui nyamuk Anopheles. Diagnosis malaria yang cepat dan akurat merupakan bagian integral dari perawatan yang tepat bagi individu yang terkena dampak dan dalam mencegah penyebaran infeksi lebih lanjut di masyarakat. Jika tidak diobati, dapat mengalami komplikasi dan mortalitas. Diagnosis klinis didasarkan pada gejala pasien dan pada temuan fisik saat pemeriksaan. Penderita malaria sering mengalami demam, kedinginan, dan penyakit seperti flu. Temuan klinis harus dikonfirmasi dengan tes laboratorium untuk malaria. Baku emas untuk konfirmasi malaria adalah pemeriksaan mikroskopik. Penentuan spesies dilakukan berdasarkan karakteristik morfologi dari empat spesies parasit malaria manusia dan eritrosit yang terinfeksi. Namun, pemeriksaan mikroskopik tidak dapat membedakan spesies parasit pejamu primata selain manusia dengan empat spesies parasit pejamu manusia. Penentuan spesies dapat menggunakan teknik molekuler seperti polymerase chain reaction (PCR) dan pengujian mikrosatelit. Tes lain untuk diagnosis adalah rapid diagnostic test (RDT), deteksi antibodi malaria menggunakan tes indirect fluorescent antibody (IFA) dan enzyme immunoassays (EIA).
ANEMIA DAN DEFISIENSI BESI PADA SISWA SLTP NEGERI I CURUG, TANGERANG Fify Henrika; T. Silangit; Riadi Wirawan
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.943

Abstract

A research was conducted to 69 female students from a junior high school (SLtP) Negeri I Curug, tangerang aged 12–14 yearsto obtain percentages of anemia and iron deficiency in female adolescents. Anemia was found on 10.2% of the students, with 4.3%of normocytic normochromic anemia and 5.8% of microcytic hypochromic anemia. Microcytic hypochromic erythrocytes was foundon 21.7% of the subjects which consist of 2.9% iron deficiency anemia, 1.4% phase 2 iron deficiency (latent) with possibility ofhemoglobinopathy, and 2.9% phase 1 iron deficiency (pre-latent) with possibility of hemoglobinopathy. Anemia without iron deficiencywith possibility of chronic diseases and/or hemoglobinopathy was 2.9%, and without anemia nor iron deficiency but with possibility ofhemoglobinopathy was 11.6%. Iron deficiency was found among 26.1% of subjects which consist of 11.6% pre-latent iron deficiency,8.7% latent iron deficiency, and 5.8% iron deficiency anemia with 2.9% and 2.9% were normocytic normochromic anemia andmicrocytic hypochromic anemia, respectively.
The Role of Neutrophil Lymphocyte Ratio , Vitamin D, and NGAL as Cardiovascular Disease Marker in Chronic Kidney Disease Sri Suryo Adiyanti; Yusra Yusra; Suzanna Immanuel; Diana Aulia; Fify Henrika; July Kumalawati
eJournal Kedokteran Indonesia Vol 9, No. 3 - Desember 2021
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.048 KB) | DOI: 10.23886/ejki.9.35.192-6

Abstract

Chronic kidney disease (CKD) patients have higher risk to develop cardiovascular disease (CVD) than non-CKD patients. Neutrophil lymphocyte ratio (NLR) in CKD patients reflects inflammation status and role as complementary prognostic marker to evaluate cardiovascular risk in stage 3 to 5 CKD. High prevalence of vitamin D deficiency commonly found in CKD patients, leads to endothelial dysfunction and increase inflammation. NGAL is used as renal injury biomarker but nowadays NGAL has been known plays important role in CVD pathophysiology. CVD identification in CKD patients is necessary to obtain CVD risk and to stratify mortality earlier in CKD patients. This study aimed to obtain the differences and continued to obtain cut off of NLR, vitamin D and NGAL in CKD patients undergoing hemodialysis (HD) with and without CVD if the differences was significantly. A cross-sectional study was conducted in dr. Cipto Mangunkusumo National Hospital Jakarta, in December- February 2020. Total subjects were 83, consists of two groups with and without the CVD. There were no significant differences of NLR and vitamin D in CKD patients undergoing hemodialysis (HD) with and without CVD. The significant difference was found only in NGAL with cut off 5.64 ng/ml. NLR was lower, meanwhile vitamin D and NGAL were higher in CKD patients undergoing HD with and without CVD.
Co-Authors Diana Aulia July Kumalawati Riadi Wirawan Sri Suryo Adiyanti Suzanna Immanuel T. Silangit Weny Rinawati YUSRA YUSRA