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All Journal JURNAL FARMASIMED (JFM) Jurnal Farmasi Sains dan Praktis
Khairani, Tetty Noverita
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Immunology & microbiology Medicine & Pharmacology Public Health

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MORINGA LEAF (Moringa Oleifera L.) ETHANOL EXTRACT CLAY MASK FORMULATION AS ANTI-AGING Nurussakinah, Nurussakinah; Fhitriana, Suzan; Khairani, Tetty Noverita; Utari, Sri
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1193

Abstract

Aging is a human physical change caused by age, psychological, and social factors, especially on the face, neck, upper arms and hands. Aging is unavoidable and goes at different speeds, depending on one's genetics, environment and lifestyle. Synthetic antiocxidant products are many circulated in the market which have a negative impact on health. However Antioxidant compound are widely spread in nature expecially in plant. Moringa leaf is one of plants that contain abundant antioxidant, alkaloids, flavonoids, phenolics, triterpenoids/steroids and tannins. Many of people Switch to natural products. Mask from natural products are not causing irritation or less side effects. clay face mask are mostly used because of their skin rejuvenating abilities. Purpose: To know either Moringa leaf ethanol extract can be formulated in clay mask preparations and the optimal effect is to prevent aging or not. Methods: the research is including how to make clay mask with ethanol extract of Moringa leaves at concentrations of 6%, 8% and 10%. The evaluation of the physical quality of the preparation, testing the effectiveness of clay masks with ethanol extract of Moringa leaves as anti-aging. Result: the preparation is qualify the characteristic test, had a pH of 4.9-5.2, a drying time of 15-23.5 minutes, an o/w emulsion type, was stable for 12 weeks of storage, and was not caused irritation. The best result of anti-aging effectiveness test was at a concentration of 10% with 36.25 moisture content, 23.25 fineness content, 33.75 pores, 20.5 blemishes and 15.5 wrinkles. Conclusion: Moringa leaf ethanol extract can be formulated in clay mask , and is able to give the best anti-aging effect at 10% formula.
ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY Khairani, Tetty Noverita; Fitri, Khairani; Andry, Muhammad; Nasution, Muhammad Amin
Jurnal Farmasi Sains dan Praktis Vol 9 No 3 (September-December 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i3.7542

Abstract

Body odor is a significant problem and is often encountered in some individuals characterized by excessive odor. A deodorant spray made from basil leaf (Ocimum Basilicum L.) extract is a product used to treat body odor caused by Staphylococcus Aureus and Staphylococcus epidermidis bacteria. The purpose of this study is to assess the efficacy of deodorant spray and basil leaf extract on bacterial activity, as well as the optimal dose of deodorant spray for lowering the activity of these bacteria. Method the research was conducted experimentally, testing antibacterial activity using agar diffusion. The results of the deodorant spray preparation test showed that the preparation was homogeneous, organoleptically brown in color, had a distinctive smell, and had a liquid texture; the pH test results met the requirements for deodorant spray 4.5-6.5. The average diameter of the inhibition zones produced from each preparation were Staphylococcus epidermidis bacteria, positive control 7 mm, negative control 10.1 mm; formula 5% 12.3 mm; formula 10% 13.3 mm; formula 15% 12.7 mm maximum concentration in inhibiting bacteria is formula 10% by 13.3 mm, while the bacteria Staphylococcus Aureus positive control 13 mm, negative control 11.2 mm, 5% formula 13.1 mm; formula 10% 13.4 mm; 15% formula 13.9 mm maximum concentration in inhibiting bacteria is 15% formula 13.9 mm. Based on the inhibitory zone created by 10% basil leaf ethanol extract, Staphylococcus epidermidis bacteria had a 13.3 mm clean zone and Staphylococcus aureus bacteria had a 26.5 mm clean zone.
Co-Authors Andry, Muhammad Fhitriana, Suzan Fitri, Khairani Nasution, Muhammad Amin Nurussakinah, Nurussakinah Utari, Sri