<![CDATA[Abstract The antioxidant effect of phenolic compounds contained in the ethanol extract of corncob waste due to oxidizing characters thats play a role in neutralizing free radicals as well as a sunscreen. This study aims at acknowledging the optimum formula of the corncobs ethanol extract as the utilization of corncob which is a waste into a sunscreen active ingredient preparation in the form of cream with the reduction of particle size of the corncobs ethanol extract. The preparation optimization parameter includes preparation physical stability test such as preparation pH test, preparation cream type, dispersive power capability and preparation adhesive power. The optimization calculation by using design software expet 9. Besides, there has also conducted an establishment of total phenolic degree of corncobs extract nanoparticles and cream preparations of corncobs extract nanoparticles. In particle size test, all of the tested formula are still inmicroparticles (over 100 nm). This indicates the need for optimization of various extracts addition, chitosan and Na-TPP to produce nanoparticles and need to try to use other crosslinking such as pectin and alginate. The ethanol extract of corncob particles coated chitosan to be added in the cream is the ethanol extract of corncob with level of 6 mg/ mL with chitosan ratio 1:1, because it has smallest average particle size. The optimum formula both of cream base or cream preparation with active ingredients of corncobs ethanol extract microparticles are creams that contains tween comparison 80 and span 80 at 15: 1 with the observation result of each parameter proved not to significantly differ from the results of software prediction of design software expert 9.The mean levels of total phenolic determination result in the corncobs ethanol extract is 48.4685 ppm and the cream preparation of corncobs extract nanoparticles is obtained 189.8923 ppm.]]>
