Claim Missing Document
Check
Articles

Found 3 Documents
Search

Sarcopenia from Pathophysiology to Clinical : Literature Review Hidayat, Rachmat; Nur Riviati
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.261

Abstract

A B S T R A C TThe causes of sarcopenia are thought to be multifactorial including: environmentalfactors, illness, activation of inflammatory pathways, mitochondrial dysfunction, lossof neuromuscular junctions, reduced number of satellite cells and changes in thequality of hormonal function. The mechanism of sarcopenia occurs because the agingprocess coupled with reduced physical activity can cause the formation of cytokinesto increase so that inflammation is easy, insulin resistant, anabolic resistance andneuromuscular impairments.
Omega-3 as an Anti-Inflammatory Modality: Literature Review Hidayat, Rachmat; Nur Riviati
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.262

Abstract

A B S T R A C TOmega-3 fatty acids are polyunsaturated fatty acids that have multiple double bonds,the first double bond is located on the third carbon atom of the omega-methyl group,the next double bond is located at the third carbon atom from the previous doublebond. The methyl omega group is the last group in the fatty acid chain. Omega-3 fattyacids are nutrients that play a vital role in the growth and development process ofbrain neuron cells for the intelligence of the born baby.
THE CORRELATION OF OMEGA 3 LEVELS WITH INTERLEUKIN-6 LEVELS IN A HEALTHY ELDERLY COMMUNITY RSMH PALEMBANG Khoirun Putra; Nur Riviati
Majalah Kedokteran Sriwijaya Vol 54, No 4 (2022): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/mks.v54i4.19662

Abstract

Ageing is associated with the geriatric syndrome, characterized by several health issues frequently associated with immunosenescence. In the elderly, immunosenescence is characterized by low-grade chronic systemic inflammation manifested as elevated levels of inflammatory molecular and cellular markers. One of the inflammatory markers is interleukin 6 (IL-6). In addition, omega-3 polyunsaturated fatty acids are a class of biologically active and anti-inflammatory fatty acids. This study aims to determine the relationship between omega-3 and interleukin-6 levels in the elderly in RSMH Palembang who are in good health. This investigation is a cross-sectional, analytic observational study. The sampling method employed was consecutive sampling. The participants in this study were members of the RSMH Palembang healthy elderly community who were 60 years of age or older. People who were malnourished, had severe illnesses like cancer or autoimmune diseases, or were taking Omega-3 supplements were not allowed in this study. As a result, 22 (55%) of 40 research subjects had low serum omega-3 levels. On the other hand, there were 35 (87.5%) samples with elevated serum IL-6 levels and 5 (12.5%) samples with normal IL-6 levels among the samples obtained. The correlation analysis showed that there was a strong negative correlation between the levels of serum omega-3 and interleukin 6 (p = 0.005). Omega 3 levels and interleukin-6 levels are correlated in the healthy elderly population of RSMH Palembang.