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All Journal JURNAL INFO KESEHATAN Jurnal Penelitian Farmasi Indonesia Majalah Farmasetika Indonesian Journal of Global Health research Jurnal Kesehatan Tambusai Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Pengabdian Masyarakat (ABDIRA) Archive: Jurnal Pengabdian Kepada Masyarakat Formosa Journal of Science and Technology (FJST) JAMAS: Jurnal Abdi Masyarakat
Eleonora Maryeta Toyo
Sekolah Tinggi Ilmu Farmasi Nusaputera
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Journal : Jurnal Farmasi dan Sains Indonesia (JFSI)

 1 
The Total Cholesterol And Body Weight Lowering Effect Of Wild Poinsettia Infusion (Euphorbia heterophylla L.) On The High Fat – Diet Induced Rats Metrikana Novembrina; Tri Wahyuni; Siti Nur Muthia Anggrahini; Eleonora Maryeta Toyo; Yithro Serang
Jurnal Farmasi & Sains Indonesia Vol 6 No 2 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no2p144-148

Abstract

Obesity is one of the risk factors which can lead to cardiovascular diseases such as hypertension, diabetes melitus and end stage renal failure. As a tropical archipelago, Indonesia has abundant potential of medicinal plantsuch as Wild Poinsettia (Euphorbia heterophilla L.), which is used by the locals as anherbal drinking to treat obesity. This research aimed to study the effectivenes of Wild poinsettia infusion in lowering total cholesterol level and body weight on the high fat – diet induced wistar male rats. The study used an experimental method with controlled post-test only design. As many as 30 high fat-diet induced male wistar rats were devided into six groups : normal control, negative control given 0,5% cmc Na as placebo, positive control given 27 mg/kgBB gemfibrozil and those given 1.25g/kgBW, 2.5g/kgBW and 5 g/kgBW Wild poinsettia infusion respectively. Prior to the treatment, the total cholesterol level of all groups were measured by using NESCO GCU®cholesterol test kit. After the treatment, the cholesterol levels were remeasured. The body weight of all testing animal was measured every week. Data was then collected and analyzed by using anava to evaluate the difference of total cholesterol level and body weight among the testing groups. According to data analysis’s results, it showed that the bodyweight and the total cholesterol level of all testing groups were significantly different (p < 0,05). Based on the results it was concluded that the Wild poinsettia infusion given to the high fat-diet induced rats can lower their total cholesterol level as well as the body weight. Keywords: high fat-diet induced rats, wild poinsettia infusion, obesity.
The Total Cholesterol And Body Weight Lowering Effect Of Wild Poinsettia Infusion (Euphorbia heterophylla L.) On The High Fat – Diet Induced Rats Metrikana Novembrina; Tri Wahyuni; Siti Nur Muthia Anggrahini; Eleonora Maryeta Toyo; Yithro Serang
Jurnal Farmasi & Sains Indonesia Vol 6 No 2 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no2p144-148

Abstract

Obesity is one of the risk factors which can lead to cardiovascular diseases such as hypertension, diabetes melitus and end stage renal failure. As a tropical archipelago, Indonesia has abundant potential of medicinal plantsuch as Wild Poinsettia (Euphorbia heterophilla L.), which is used by the locals as anherbal drinking to treat obesity. This research aimed to study the effectivenes of Wild poinsettia infusion in lowering total cholesterol level and body weight on the high fat – diet induced wistar male rats. The study used an experimental method with controlled post-test only design. As many as 30 high fat-diet induced male wistar rats were devided into six groups : normal control, negative control given 0,5% cmc Na as placebo, positive control given 27 mg/kgBB gemfibrozil and those given 1.25g/kgBW, 2.5g/kgBW and 5 g/kgBW Wild poinsettia infusion respectively. Prior to the treatment, the total cholesterol level of all groups were measured by using NESCO GCU®cholesterol test kit. After the treatment, the cholesterol levels were remeasured. The body weight of all testing animal was measured every week. Data was then collected and analyzed by using anava to evaluate the difference of total cholesterol level and body weight among the testing groups. According to data analysis’s results, it showed that the bodyweight and the total cholesterol level of all testing groups were significantly different (p < 0,05). Based on the results it was concluded that the Wild poinsettia infusion given to the high fat-diet induced rats can lower their total cholesterol level as well as the body weight. Keywords: high fat-diet induced rats, wild poinsettia infusion, obesity.
The Total Cholesterol And Body Weight Lowering Effect Of Wild Poinsettia Infusion (Euphorbia heterophylla L.) On The High Fat – Diet Induced Rats Metrikana Novembrina; Tri Wahyuni; Siti Nur Muthia Anggrahini; Eleonora Maryeta Toyo; Yithro Serang
Jurnal Farmasi & Sains Indonesia Vol 6 No 2 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no2p144-148

Abstract

Obesity is one of the risk factors which can lead to cardiovascular diseases such as hypertension, diabetes melitus and end stage renal failure. As a tropical archipelago, Indonesia has abundant potential of medicinal plantsuch as Wild Poinsettia (Euphorbia heterophilla L.), which is used by the locals as anherbal drinking to treat obesity. This research aimed to study the effectivenes of Wild poinsettia infusion in lowering total cholesterol level and body weight on the high fat – diet induced wistar male rats. The study used an experimental method with controlled post-test only design. As many as 30 high fat-diet induced male wistar rats were devided into six groups : normal control, negative control given 0,5% cmc Na as placebo, positive control given 27 mg/kgBB gemfibrozil and those given 1.25g/kgBW, 2.5g/kgBW and 5 g/kgBW Wild poinsettia infusion respectively. Prior to the treatment, the total cholesterol level of all groups were measured by using NESCO GCU®cholesterol test kit. After the treatment, the cholesterol levels were remeasured. The body weight of all testing animal was measured every week. Data was then collected and analyzed by using anava to evaluate the difference of total cholesterol level and body weight among the testing groups. According to data analysis’s results, it showed that the bodyweight and the total cholesterol level of all testing groups were significantly different (p < 0,05). Based on the results it was concluded that the Wild poinsettia infusion given to the high fat-diet induced rats can lower their total cholesterol level as well as the body weight. Keywords: high fat-diet induced rats, wild poinsettia infusion, obesity.
The Total Cholesterol And Body Weight Lowering Effect Of Wild Poinsettia Infusion (Euphorbia heterophylla L.) On The High Fat – Diet Induced Rats Metrikana Novembrina; Tri Wahyuni; Siti Nur Muthia Anggrahini; Eleonora Maryeta Toyo; Yithro Serang
Jurnal Farmasi & Sains Indonesia Vol 6 No 2 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no2p144-148

Abstract

Obesity is one of the risk factors which can lead to cardiovascular diseases such as hypertension, diabetes melitus and end stage renal failure. As a tropical archipelago, Indonesia has abundant potential of medicinal plantsuch as Wild Poinsettia (Euphorbia heterophilla L.), which is used by the locals as anherbal drinking to treat obesity. This research aimed to study the effectivenes of Wild poinsettia infusion in lowering total cholesterol level and body weight on the high fat – diet induced wistar male rats. The study used an experimental method with controlled post-test only design. As many as 30 high fat-diet induced male wistar rats were devided into six groups : normal control, negative control given 0,5% cmc Na as placebo, positive control given 27 mg/kgBB gemfibrozil and those given 1.25g/kgBW, 2.5g/kgBW and 5 g/kgBW Wild poinsettia infusion respectively. Prior to the treatment, the total cholesterol level of all groups were measured by using NESCO GCU®cholesterol test kit. After the treatment, the cholesterol levels were remeasured. The body weight of all testing animal was measured every week. Data was then collected and analyzed by using anava to evaluate the difference of total cholesterol level and body weight among the testing groups. According to data analysis’s results, it showed that the bodyweight and the total cholesterol level of all testing groups were significantly different (p < 0,05). Based on the results it was concluded that the Wild poinsettia infusion given to the high fat-diet induced rats can lower their total cholesterol level as well as the body weight. Keywords: high fat-diet induced rats, wild poinsettia infusion, obesity.
The Total Cholesterol And Body Weight Lowering Effect Of Wild Poinsettia Infusion (Euphorbia heterophylla L.) On The High Fat – Diet Induced Rats Metrikana Novembrina; Tri Wahyuni; Siti Nur Muthia Anggrahini; Eleonora Maryeta Toyo; Yithro Serang
Jurnal Farmasi & Sains Indonesia Vol 6 No 2 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no2p144-148

Abstract

Obesity is one of the risk factors which can lead to cardiovascular diseases such as hypertension, diabetes melitus and end stage renal failure. As a tropical archipelago, Indonesia has abundant potential of medicinal plantsuch as Wild Poinsettia (Euphorbia heterophilla L.), which is used by the locals as anherbal drinking to treat obesity. This research aimed to study the effectivenes of Wild poinsettia infusion in lowering total cholesterol level and body weight on the high fat – diet induced wistar male rats. The study used an experimental method with controlled post-test only design. As many as 30 high fat-diet induced male wistar rats were devided into six groups : normal control, negative control given 0,5% cmc Na as placebo, positive control given 27 mg/kgBB gemfibrozil and those given 1.25g/kgBW, 2.5g/kgBW and 5 g/kgBW Wild poinsettia infusion respectively. Prior to the treatment, the total cholesterol level of all groups were measured by using NESCO GCU®cholesterol test kit. After the treatment, the cholesterol levels were remeasured. The body weight of all testing animal was measured every week. Data was then collected and analyzed by using anava to evaluate the difference of total cholesterol level and body weight among the testing groups. According to data analysis’s results, it showed that the bodyweight and the total cholesterol level of all testing groups were significantly different (p < 0,05). Based on the results it was concluded that the Wild poinsettia infusion given to the high fat-diet induced rats can lower their total cholesterol level as well as the body weight. Keywords: high fat-diet induced rats, wild poinsettia infusion, obesity.
AKTIVITAS FRAKSI EKSTRAK ETANOL DAUN MURBEI TERHADAP PROFIL LIPID DARAH DAN ATEROSKLEROSIS TIKUS YANG HIPERLIPIDEMIA Eleonora Maryeta Toyo; Rina Herowati; Arief Nurrochmad
Jurnal Farmasi & Sains Indonesia Vol 2 No 1 (2019)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Daun murbei merupakan salah satu tanaman yang banyak digunakan sebagai antidiabetes dan antihiperlipidemia. Penelitian ini bertujuan untuk mengetahui pengaruh ketiga fraksi etanol daun murbei (n-heksana, etil asetat, dan air) sebagai antihiperlipidemi dan anti aterosklerosis berupa penurunan ketebalan dinding aorta pada tikus putih jantan galur wistar yang diberi diet tinggi lemak dan PTU. Penelitian ini menggunakan 40 ekor tikus, yang terdiri dari satu kelompok diberi diet normal dan tujuh kelompok diberi diet tinggi lemak dan PTU selama satu bulan. Terapi perlakuan diberikan selama 14 hari. Kelompok I sebagai kontrol normal diberi Confeed PAR-S, kelompok II sebagai kontrol negatif diberi HFD dan CMC Na 0,5%, kelompok III sebagai kontrol positif diberi HFD dan simvastatin 0,9 mg/kg BB, kelompok IV sebagai kontrol positif diberi HFD dan gemfibrosil 0,9 mg/kg BB, kelompok V diberi HFD dan ekstrak etanol daun murbei dengan dosis 500 mg/kg BB, kelompok VI diberi HFD dan fraksi n-heksana dosis 60 mg/kg BB, kelompok VII diberi HFD dan fraksi etil asetat dosis 40 mg/kg BB, dan kelompok VIII diberi HFD dan fraksi air dosis 400 mg/kg BB. Semua tikus diukur profil lipid darah pada hari ke 0, 28, 35, dan 42. Hasil penelitian ini menunjukan bahwa fraksi etil asetat memiliki efek sebagai antihiperlipidemia dan anti aterosklerosis berupa penurunanan ketebalan dinding aorta abdominalis pada tikus hiperlipidemia
KEJADIAN STAGNANT DAN STOCKOUT OBAT KARDIOVASKULER DI INSTALASI FARMASI RUMAH SAKIT Eleonora Maryeta Toyo; Sri Suwarni; Yolanda Ernidiasanti
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p41-49

Abstract

Drug management is carried out as an effort to control drug inventory in hospital pharmacy installations to know the incidence of stagnant and stockout of cardiovascular drugs from the internal medicine specialist poly. This research was conducted in March-April 2021, with a cross-sectional study design with retrospective data search. The data instrument used is an electronic stock card specifically for the use of cardiovascular drugs in hospital outpatient installations, including; antianginal, antidyslipidemic, antihypertensive, and antiplatelet drugs. The number of samples used was 50 items of cardiovascular drugs. Data processing is carried out qualitatively and quantitatively. The results showed that the highest number was found in the antihypertensive therapy class as many as 32 items with an amount of stagnant 12% and a total stockout of 31.3%. Keywords: Cardiovascular Medicine, Stagnant, Stockout, Hospital
Co-Authors Arief Nurrochmad Delia Paramita Ferika Indarsari Ferika Indra Sari Ferika Indrasari Karol Giovani Battista Leki Metrikana Novembrina Nanda Dwi Akbar Priska Ernestina Tenda Ratna Wulandari Ratna Rina Herowati Siti Munawaroh Siti Nur Muthia Anggrahini Sri Asih Handayani Sri Suwarni Suwito Woro Tri Wahyuni Yithro Serang Yolanda Ernidiasanti