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Penyuluhan Manfaat Umbi Lokal Canna Edulis Kerr di Masyarakat Ferika Indrasari; Metrikana Novembrina; Rizky Ardian Hartanto Sawal
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 2, No 3 (2022): Abdira, Juli
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v2i3.186

Abstract

Dependence on rice and wheat can be maintained or reduced by increasing the diet through changing the image of tubers such as the local tuber Canna Edulis Kerr. The purpose of service is to improve food security in the community. The method of implementing the activity is counseling using power point media. The results of the activity went well from licensing to the end of the activity. Conclusion Participants get direct benefits related to counseling the benefits of local tuber Canna edulis kerr in the community.
Pengaruh Pelarut N-Heksan, Etil Asetat, Dan Etanol 96% Terhadap Kadar Flavonoid dan Aktivitas Antioksidan Kulit Buah Lamtoro (Leucaena leucocephala) atalia tamo ina bulu; Metrikana Novembrina
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p81-86

Abstract

Lamtoro rind waste in Indonesia is produced in large quantities so it can become a problem for the environment if not managed properly. Lamtoro rind extract contains chemical compounds such as flavonoids, alkaloids, saponins, phenolics, and tannins. Flavonoid compounds, one of the phenolic groups widely found in plant tissues, can act as antioxidants. This study aims to examine the effect of N-hexane, ethyl acetate, and 96% ethanol on the levels of flavonoids and the antioxidant activity of lamtoro rind (Leucaena leucocephala). Lamtoro rind was made simplicial and extracted by maceration method using N-hexane, ethyl acetate, and 96% ethanol separately for 3x24 hours. Each extract was analyzed to determine the levels of flavonoids by UV-Vis spectrophotometry method and antioxidant activity using the DPPH (1,1-diphenyl-2-picrylhidrazyl) method. The results of the analysis showed that 96% ethanol gave the extract with the highest levels of flavonoids, followed by ethyl acetate and N-hexane of 15.345 µg/g, 14.899 µg/g and 10.234 µg/g respectively. In addition, the antioxidant activity of lamtoro rind extract was also shown to be higher in 96% ethanol extract compared to ethyl acetate extract and n-hexane extract calculated with IC50 values of 39.914 ppm, 30.788 ppm, and 164.304 ppm respectively. Based on this study, it can be concluded that 96% ethanol resulted in lamtoro rind extract with higher levels of flavonoids and stronger antioxidant activity compared to using N-hexane or ethyl acetate as solvents. These results indicate that lamtoro rind has the potential as a useful source of flavonoids and antioxidants.
Efektivitas Ekstrak Etanol Herba Patik Emas (Euphorbia heterophylla L.) dalam Menurunkan Kolesterol Total Pada Tikus Jantan Obesitas terinduksi Diet Tinggi Lemak. Metrikana Novembrina; Tri Wahyuni; Siti Nur Muthia Anggrahini; Atalia Tamo Ina Bulu
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p192-196

Abstract

Obesity can cause various health problems such as cardiovascular disease and methabolic syndromme (insuline resistance, type 2 diabetes, hypertension und dyslipidemia). Various drug treatments have also been introduced into the community such as simvastatin, gemfibrozil and klorfibrat. These medicines are also considered unsafe if it is used permanently or excessively. Obesity can also bring about dyslipidemia. Hence, the bioactive agent which can burn the visceral fat is definetely needed. In Indonesia there is a great number of weeds which have been identified as a plant that has certain pharmacological effect in human’s body. One of them is wild poinsettia (Euphorbia heterophylla L.) which has also been proven to be effective as an antioxidant and blood glucose-lowering agent through some studies. This was a laboratory experimental study with a post-test only controlled group design. A number of 30 wistar strain white male rats were devided into 6 groups. Group 1 was normal control, group 2 was negative control (CMC Na 0,5 %), Group 3 was a positive control (gemfibrozil), group 4,5 and 6 were the ethanolic extract of wild poinsettia’s herbs in the doses of 250, 500 and 750 mg/kgBW respectively. Previously the total cholesterol level was measured to all testing animals. Before the trial, all testing animals except normal control were given high fat diet for two weeks. The total cholesterol and the body weight were then measured to observe the increase of the level. To the group 2,3,4,5 and 6 then were given the plecebo (CMC Na 0,5%), gemfibrozil, the extracts of 250, 500, and 750 mg/kgBW respectively for two weeks. The body weight and the total cholesterol were then measured again. The results showed that the ethanol extract of the wild poinsettia herb’s extract at a dose of 250 mg / kgBW was effective in reducing total cholesterol levels compared to the negative control. The dose of 750 mg / kgBW showed a maximum lowering effect of total cholesterol levels. Based on the results, it can be concluded that the ethanol extract of wild poinsettia has effectiveness in reducing total cholesterol levels of obese male rats induced by a high-fat diet. 
Co-Authors Atalia Tamo Ina Bulu Atalia Tamo Ina Bulu Eleonora Maryeta Toyo Ferika Indrasari Sawal, Rizky Ardian Hartanto Siti Nur Muthia Anggrahini Tri Wahyuni Yithro Serang