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All Journal Medula JK Unila (Jurnal Kedokteran Universitas Lampung)
Nadia Rosmalia Dewi
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Agriculture, Biological Sciences & Forestry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Penatalaksanaan Holistik Penyakit Herpes Zoster pada Pasien Remaja Laki-Laki 15 Tahun dengan Pendekatan Kedokteran Keluarga Nadia Rosmalia Dewi; Dian Isti Angraini
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.100

Abstract

Shingles is clinical manifestations due to reactivation of varicella zoster virus (VZV). in sensory ganglia that were previously exposed to primary varicella infection. The incidence of HZ increases with age and is rarely found in children. Shingles can occur in children who have primary primary infections, immunocompromised conditions, and who are related in the first year of life. The purpose of this study is to Identify internal and external risk factors and clinical problems in patients, as well as holistically managing patients by applying a family doctor based on evidence-based medicine through a patient centered approach and family approach. This study analysis is a case report. Primary data were obtained through history taking (autoanamnesis from the patient and alloanamnesis from the patient's family) physical examination and home visits. Secondary data were obtained from the patient's medical record. Assessment is based on a holistic diagnosis from the beginning, process, and end of study in a qualitative and quantitative manner. Patient A, 15 years old, who has been diagnosed with Herpes Zoster without complications has concerns about his health condition, the patient feels inferior and is afraid that his illness cannot be cured and is afraid of transmitting it to other family members. Patient's expectation is that complaints disappear completely and do not recur, so that they can be comfortable in their normal activities. Limitation of the patient's knowledge of the illness and bad lifestyle is a factor causing problems that occur in patients and families. The diagnosis of shingles in this case is in accordance with several theories and critical studies from recent research. Management has been given in accordance with management guidelines. Good developments were seen in patients ranging from decreased clinical symptoms to behavioral changes after a family-approach and patient-centered Evident Based Medicine intervention.
Pengaruh Pemberian Ekstrak Etanol Rimpang Lengkuas (Alpinia galangal L.Willd) Terhadap Gambaran Histopatologi Ginjal Mencit Jantan (Mus musculus L.) yang Diinduksi oleh Monosodium Glutamat (MSG) Muhartono Muhartono; Mukhlis Imanto; Nadia Rosmalia Dewi
Jurnal Kedokteran Universitas Lampung Vol 2, No 1 (2018): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v2i1.1909

Abstract

Monosodium Glutamat (MSG) adalah garam natrium glutamat yang digunakan sebagai penambah rasa. Menurut Riset Kesehatan Dasar tahun 2013 sekitar 77,3%. MSG dikonsumsi masyarakat Indonesia. MSG dapat membentuk radikal bebas sehingga menyebabkan kerusakan organ-organ tubuh salah satunya organ ginjal manusia. Rimpang lengkuas adalah salah satu bahan alami yang mengandung antioksidan yang dapat mecegah kerusakan organ akibat radikal bebas. Tujuan daripenelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak etanol rimpang lengkuas terhadap gambaran histopatolgi ginjal mencit yang diinduksi MSG. Desain penelitian ini adalah eksperimental dengan 5 kelompok perlakuan, tiap kelompok terdiri dari 5 ekor mencit (Mus Musculus L.) strain DDY. Kelompok K(-) (kontrol -) tidak diberi perlakuan; kelompok K+(kontrol +) diberikan MSG 4mg/grBB; kelompok P1 (perlakuan 1) diberikan MSG 4mg/kgBB + ekstrrak etanol rimpang lengkuas 14mg/20grBB; kelompok P2 (perlakuan 2) diberikan MSG 4mg/kgBB + ekstrrak etanol rimpang lengkuas 28mg/20grBB; kelompok P3 (perlakuan 3) diberikan MSG 4mg/kgBB + ekstrrak etanol rimpang lengkuas 56mg/20grBB. Berdasarkan hasil uji statistik One Way ANOVA didapatakan hasil yang bermakna dan dilanjutkan dengan uji Post Hoc. Pada uji Post Hoc terlihat adanya pengaruh perlakuan terhadap penurunann degenerasi sel ginjal yang bermakna secara statistikterhadap peningkatan dosis ekstrak etanol rimpang lengkuas. Terdapat pengaruh pemberian ekstrak etanol rimpang lengkuas terhadap gambaran histopatologi ginjal mencit yang diinduksi MSG.Kata kunci: Ekstrak lengkuas, histopatologi ginjal, monosodium glutamat
Co-Authors Dian Isti Angraini Muhartono Muhartono Mukhlis Imanto