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All Journal Lantanida Journal Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) Jurnal Pengabdian Masyarakat Bangsa
Rahayu, Hanis Kusumawati
Universitas Mulawarman, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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The Effect of Sambiloto Extract on the Expression of β Estrogen Receptors in Ovaries and Lust Cycle in Mice Model PCOS - Insulin Resistance Hanis Kusumawati Rahayu
Journal of Ners and Midwifery Vol 8, No 1 (2021)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v8i1.ART.p078-084

Abstract

Infertility was a serious problem in the reproductive period, one of the caused of infertility were common in women of childbearing age group is Polycystic Ovary Syndrome (PCOS).Sambiloto (Andrographis paniculata Nees), had been already known contain flavonoid and lactones. The purpose of this research had to determine the effect of various doses of sambiloto extract with the expression of β estrogen receptor and estrus cycle in the mice model of PCOS - insulin resistance. This research was an animal model experimental laboratory research with a completely randomized design (CRD).The results showed that sambiloto extract therapy in treatment group had an improvement estrus cycle compared with control group. Positive control group, almost 90% had persistent anestrus condition. In treatment group 1 and 2 in the last vagina smear obtained anestrus condition as much as 60% in diestrus and medestrus phase. Whereas treatment groups 3 all experimental animals in a estrus state by proestrus and estrus phase. β Estrogen receptor expression had tested by Kruskal Wallis test for overall treatment, obtained significantly different results (p ≤ 0.002) followed by Mann - Whitney, showed that immunoreactive cells score from highest to lowest occurred in each group Negative control (KN), P3, P2, P1 and Positive Control (KP).It could be concluded that sambiloto extract at dose 18mg/kgbb, 36mg/kgbb, and 72mg/kgbb had been given an overview of the differences expression of β estrogen receptor, could change the estrus cycle of female mice models of insulin resistance PCOS.
TINJAUAN LITERATUR: BIOAKUMULASI LOGAM BERAT PADA IKAN DI PERAIRAN INDONESIA Said Ali Akbar; Hanis Kusumawati Rahayu
Lantanida Journal Vol 11, No 1 (2023)
Publisher : UIN AR-RANIRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/lj.v11i1.17834

Abstract

Heavy metals are frequently employed in a variety of industries, including industry, agriculture, food processing, and domestic appliances. Heavy metal concentrations will be extremely high in locations with residential, mining, and manufacturing activity. The concentration of heavy metals in fish reflects the state of heavy metal pollution in the ecosystem. Heavy metal accumulation in aquatic creatures' organs can occasionally exceed the level of heavy metals in their environment. The purpose of this literature review is to give information on the bioaccumulation of heavy metals in fish in Indonesian seas. 38 fish species were recorded, and literacy parameters in the form of sample locations and levels, units and types of heavy metals discovered were summarized. Pb > Cd > Hg > Cu > As > Zn > Cr > Mn > Fe is the order of metal abundance discovered. It is advised that heavy metal contamination studies be carried out in the future as part of the government's strategy for tracking down this problem.
Strategi Peningkatan Pemanfaatan E-Portofolio Pada Dosen, Mahasiswa Fakultas Kedokteran Universitas Mulawarman Angkatan 2021-2022 Hanis Kusumawati Rahayu; Sulistiawati; Hany Puspita Aryani; Karisma Dwi Ana; Elly Rustanti
Jurnal Pengabdian Masyarakat Bangsa Vol. 1 No. 5 (2023): Juli
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v1i5.137

Abstract

Tantangan dunia pendidikan semakin besar. Disrupsi teknologi semakin menuntut untuk penerapan digital literasi menuju era 5.0 society dalam dunia pendidikan khususnya Pendidikan tinggi disegala aspek. Begitu pula dengan Fakultas Kedokteran Universitas Mulawarman, olehkarenanya fakultas memberikan terobosan dalam membuat log book kegiatan pembelajaran mahasiswa dan juga prestasi baik akademik maupun non akademik kedalam bentuk digital yakni menerapkan pada platform e-portofolio hal ini di harapkan sebagai bentuk mendidik sumber daya manusia agar dapat berkontribusi dalam menghasilkan manusia berkualitas yang memiliki kemampuan berpikir kritis, kreatif, komunikasi serta berkolaborasi. Metode yang digunakan dalam pengabdian masyarakat ini berupa pembuatan buku panduan penggunaan e-portofolio beserta video tutorial. Perangkat tersebut kemudian di sosialisasikan kepada seluruh dosen dan mahasiswa Angkatan 2021 – 2022 yang berjumlah Hasil dari sosialisasi kepada mahasiswa didapatkan peningkatan pengetahuan pemanfaatan e-portofolio di Fakultas Kedokteran Universitas Mulawarman dengan nilai signifikansi sebesar 0.000.
Co-Authors Elly Rustanti Hany Puspita Aryani, Hany Karisma Dwi Ana Said Ali Akbar Sulistiawati