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All Journal HOSPITAL MAJAPAHIT (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT) Journal of Holistics and Health Sciences (JHHS) Hospital Majapahit : Jurnal Ilmiah Kesehatan Politeknik Kesehatan Mojokerto STRADA Jurnal Ilmiah Kesehatan Prima Wiyata Health Jurnal Pengabdian Masyarakat Bangsa JPK : Jurnal Penelitian Kesehatan
Hany Puspita Aryani, Hany
Sekolah Tinggi Ilmu Kesehatan Husada Jombang, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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PERUBAHAN LEVEL INSULIN DAN PERKEMBANGAN FOLLICLE PADA TIKUS (RATTUS NORVEGICUS) SEBAGAI MODEL PENGOBATAN SOPK- RESISTENSI INSULIN MELALUI PEMBERIAN EKSTRAK DAUN SAMBILOTO Aryani, Hany Puspita
HOSPITAL MAJAPAHIT (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT) Vol 6, No 1 (2014): HOSPITAL MAJAPAHIT VOL 6 NO 1
Publisher : HOSPITAL MAJAPAHIT (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.10475/hm.v6i1.465

Abstract

SOPK is a disturbance in women reproduction periods with multifactorial etiology. One of the SOPK causes is insulin resistance that is the disruption of insulin action causing hyperinsulinemia1. Sambiloto plant extract has certain content one of which is Diterpenlactone which can be used as diuretic. The content of sambiloto extract is thought to be able to stimulate insulin release and obstruct glucose absorption by obstructing alphaglucocidaseand alpha-amylase enzymes which will reduce glucose levels in blood. The objective of this study is to know the change in insulin content and the follicle development in mice as SOPK model – insulin resistance treated with sambiloto extract. The study was a laboratory experiment, with complete random sampling design. The control and experimental groups composed of 25 white mice (Ratus norvegicus) were randomly divided into 5 groups, with 5 mice in each group. Control groups (K) were K-, which was not treated, and K+, which was made as SOPK model, that is insulin resistance given testosterone propionate for 28 days. Experimental groups are divided into Group treated with sambiloto extract dosage of 18mg/100g body weight/day, Group treated with sambiloto extract dosage of 36mg/100g body weight/day, and Group treated with sambiloto extract dosage of 72mg/100g body weight/day. The last research is to known how is the insulin and follicles growth.The results of the study showed that the average of Anova test with the biggest value of 8000 was primary follicle in group K- and followed by groups P1 and P3 with sambiloto extract dosage of 18mg and 36 mg with the average of 6.8000. The result of normality test with oneway sample kolmogorov smirnov test showed that primary, secondary, tertiary, and de Graff follicles had the value p> 0.05. This could be concluded that the data had normal distribution. The LSD test showed significant difference between the development of primary follicles in control groups and in treated group with p: 0.031, and the development of de Graff follicles in control groups and in treated groups with p: 0.002. Therefore, it could be concluded that there was a significant relationship with the use of sambiloto extract.The giving of sambiloto extract proved to be able to increase the development of primary and de Graff follicles. With significant p value 0.031 and 0.002 where p<0.05.Keywords: sambiloto extract, insulin and development of follicles
Perubahan Level Insulin Dan Perkembangan Follicle Pada Tikus (Rattus Norvegicus) Sebagai Model Pengobatan SOPK- Resistensi Insulin Melalui Pemberian Ekstrak Daun Sambiloto Hany Puspita Aryani
Hospital Majapahit (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT MOJOKERTO) Vol 6 No 1 (2014): Hospital Majapahit
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Majapahit Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.053 KB)

Abstract

SOPK is a disturbance in women reproduction periods with multifactorial etiology. One of the SOPK causes is insulin resistance that is the disruption of insulin action causing hyperinsulinemia1. Sambiloto plant extract has certain content one of which is Diterpen lactone which can be used as diuretic. The content of sambiloto extract is thought to be able to stimulate insulin release and obstruct glucose absorption by obstructing alphaglucocidase and alpha-amylase enzymes which will reduce glucose levels in blood. The objective of this study is to know the change in insulin content and the follicle development in mice as SOPK model – insulin resistance treated with sambiloto extract. The study was a laboratory experiment, with complete random sampling design. The control and experimental groups composed of 25 white mice (Ratus norvegicus) were randomly divided into 5 groups, with 5 mice in each group. Control groups (K) were K-, which was not treated, and K+, which was made as SOPK model, that is insulin resistance given testosterone propionate for 28 days. Experimental groups are divided into Group treated with sambiloto extract dosage of 18mg/100g body weight/day, Group treated with sambiloto extract dosage of 36mg/100g body weight/day, and Group treated with sambiloto extract dosage of 72mg/100g body weight/day. The last research is to known how is the insulin and follicles growth.The results of the study showed that the average of Anova test with the biggest value of 8000 was primary follicle in group K- and followed by groups P1 and P3 with sambiloto extract dosage of 18mg and 36 mg with the average of 6.8000. The result of normality test with oneway sample kolmogorov smirnov test showed that primary, secondary, tertiary, and de Graff follicles had the value p> 0.05. This could be concluded that the data had normal distribution. The LSD test showed significant difference between the development of primary follicles in control groups and in treated group with p: 0.031, and the development of de Graff follicles in control groups and in treated groups with p: 0.002. Therefore, it could be concluded that there was a significant relationship with the use of sambiloto extract.The giving of sambiloto extract proved to be able to increase the development of primary and de Graff follicles. With significant p value 0.031 and 0.002 where p<0.05.
An IGF-1 Levels Decrease in SOPK-RI Model Mice After A Low-Carb Diet Ermawati Ermawati; Budi Santoso; Widjiati Widjiati; Hany Puspita Aryani
STRADA Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Institut Ilmu Kesehatan STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.546 KB) | DOI: 10.30994/sjik.v9i2.298

Abstract

The aim of this study is to analyze the IGF-1 levels decrease in mice modeled by Polycystic Ovary Syndrome Insulin Resistance post carbohydrate high in protein. True Experimental Design with a Posttest Control Group Design research using 36 tails, female Wistar Rattus Norvegicus Strains, 3 months, 100-200 grams and randomly divided into 3 groups, namely K-(n =12, negative control group), K+(n=12, positive control group) and KP(n=12, treatment group). SOPK-IR modeling is done by mice in the injection of the hormone testosterone provionate at a dose of 100 mg/kg BW for 28 days, on the last day after injection a vaginal swab is performed to identify the condition of diestrus. The measurement of IGF-1 levels used the Enzyme-Linked Immunosorbent Assay method. Data analysis techniques used ANOVA test and LSD post hoc test. The results obtained mean levels of IGF-1 at K- (234.126±32.568) ng/mL, K+ (169.662±30.150) ng/mL, KP (146.528±29.562) ng/mL (p=0.000)
RELATIONSHIP OF FAMILY SUPPORT WITH INDEPENDENCE OF SELF-CARE IN MENTAL RETARDATION IN SLB TN II MANCAR VILLAGE, PETERONGAN DISTRICT Yoga Rosita; Hany Puspita Aryani; Sylvie Puspita
PRIMA WIYATA HEALTH Vol 1 No 1 (2020): Prima Wiyata Health, Januari 2020
Publisher : LPPM STIKES HUSADA JOMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (338.936 KB)

Abstract

The development of children who experience mental retardation will have an influence on the ability of children and the involvement of children to function in the environment. Children are not able to be independent as individuals who are able to carry out their own daily activities (motoric), limitations in understanding social behavior and the development of social skills. This study aims to determine the relationship of family support with self-care independence in mentally retarded children at SLB TN II in Mancar village, Peterongan District, Jombang Regency. This study uses the Correlational Quantitative Analytical approach. The sample technique used was total sampling, namely all mentally retarded children at SLB TN II in Mancar village, Peterongan District, Jombang Regency, 24 people. Data collection uses a questionnaire to measure family support and independence of self-care of children. Chi Square data analysis and contingency coefficient. Based on the results of the analysis obtained the value of p = 0,000 (p <0.05), meaning that there is a relationship between family support and self-care independence in mentally retarded children at SLB TN II in Mancar village, Peterongan District, Jombang Regency with the strength of relationships in sufficient categories. Parents are expected to be able to provide support as needed by mentally retarded children to increase their independence in self-care.
PENGARUH JIGSAW PUZZLES GAME SEBAGAI TERAPI AKTIVITAS KELOMPOK TERHADAP KEMAMPUAN INTERAKSI SOSIAL PADA LANSIA DI DESA DUKUH KLOPO KECAMATAN PETERONGAN KABUPATEN JOMBANG Yoseph Copertino Tna’auni; Hany Puspita Aryani; Rista Dian Anggraini
PRIMA WIYATA HEALTH Vol 2 No 1 (2021): Prima Wiyata Health, Januari 2021
Publisher : LPPM STIKES HUSADA JOMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.758 KB)

Abstract

Humans naturally experience a decrease / change in their physical and psychological conditions which are interconnected with one another which is often referred to as the aging process. This situation tends to cause health problems especially in old age. The design of this research was pre-experimental with the type of one group pre-test- post-test design. The population of all elderly in the Klopo hamlet was 42 people with purposive sampling technique, with a sample size of 20 people and data collection using a questionnaire with the Wilcoxon test. The results of the study most of the respondents 'perceptions before the extension were carried out were less than 13 respondents (65%), most of the respondents' perceptions after counseling were good as many as 16 respondents (80%). The results of SPSS 16 for windows using the Wilcoxon test with a significant level of 0.05 obtained ρ = 0.000 <α (0.05), so Ho (null hypothesis) is rejected, meaning that there is an effect of jigsaw puzzles games as group activity therapy on social interaction skills in the elderly in Dukuh Klopo Village, Peterongan District, Jombang Regency. Jigsaw puzzle game is one of the effective nursing interventions to improve the client's ability to interact. Giving therapy allows clients to support each other, learn to establish interpersonal relationships, feel togetherness and can provide input on the experiences of each client, so that it will increase the ability to socialize with others around them.
Hubungan Rheumatoid Arthritis dengan Kejadian Insomnia pada Usia Lanjut : Relationship between Rheumatoid Arthritis and Insomnia in Old Age Sri Wulandari; Warda Anil Masyayih; Rista Dian Anggraini; Hany Puspita Aryani
Journal of Holistics and Health Sciences (JHHS) Vol. 5 No. 1 (2023): Journal of Holistics and Health Sciences (JHHS), Maret
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/jhhs.v5i1.256

Abstract

One of the health problems often experienced by the elderly is rheumatoid arthritis. Joint disorders experienced by people with rheumatoid arthritis will have an impact on physical problems such as insomnia and will later affect sleep quality. Design correlational analytical research with a cross-sectional approach. The sample was all elderly people with rheumatoid arthritis as many as 30 respondents using the smapling purposive sampling technique. Data collection using KSPBJ insomnia rating scale questionnaires. Analyse data with Spearman’s Rho test with 0.05 significance. The results of the study were known that in respondents who experienced rheumatoid arthritis with severe pain all experienced severe insomnia, which was 13.3%. Meanwhile, in respondents who experienced rheumatoid arthritis with mild pain, all experienced mild insomnia, which was 36.7%. The results of the data analysis with the Spearman Rho test found that there was a relationship between rheumatoid arthritis and insomnia in old age in Kreteranggon Village, Sambeng District, Lamongan Regency (ρ =0,000, α=0.05, r=0.699). Based on the description above, it can be concluded that there is a relationship in the strong category between rheumathoid arthritis and the incidence of insomnia. ABSTRAK Salah satu masalah kesehatan yang sering dialami oleh lansia adalah rheumatoid arthritis. Gangguan sendi yang dialami penderita rheumatoid arthritis akan berdampak pada masalah fisik seperti insomnia dan nantinya akan berpengaruh pada kualitas tidur. Rancangan penelitian analitik korelasional dengan pendekatan cross sectional. Sampelnya semua lansia penderita penyakit rheumatoid arthritis sebanyak 30 responden dengan menggunakan teknik sampling purposive sampling. Pengumpulan data menggunakan kuesioner KSPBJ insomnia rating scale. Analisa data dengan uji Spearman’s Rho dengan signifikasi 0,05. Hasil Penelitian diketahui bahwa pada responden yang mengalami rheumatoid arthritis dengan nyeri berat seluruhnya mengalami insomnia berat yaitu sebanyak 13,3%. Sedangkan pada responden yang mengalami rheumatoid arthritis dengan nyeri ringan seluruhnya mengalami insomnia ringan yaitu sebanyak 36,7%. Hasil analisa data dengan uji Spearman Rho didapatkan ada hubungan rheumatoid arthritis dengan kejadian insomnia pada usia lanjut di Desa Kreteranggon Kecamatan Sambeng Kabupaten Lamongan ( ρ =0,000, α=0,05, r=0,699).  Berdasarkan uraian diatas dapat disimpulkan bahwa Ada hubungan dalam kategori kuat antara rheumathoid Arthritis dengan kejadian insomnia.
Strategi Peningkatan Pemanfaatan E-Portofolio Pada Dosen, Mahasiswa Fakultas Kedokteran Universitas Mulawarman Angkatan 2021-2022 Hanis Kusumawati Rahayu; Sulistiawati; Hany Puspita Aryani; Karisma Dwi Ana; Elly Rustanti
Jurnal Pengabdian Masyarakat Bangsa Vol. 1 No. 5 (2023): Juli
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v1i5.137

Abstract

Tantangan dunia pendidikan semakin besar. Disrupsi teknologi semakin menuntut untuk penerapan digital literasi menuju era 5.0 society dalam dunia pendidikan khususnya Pendidikan tinggi disegala aspek. Begitu pula dengan Fakultas Kedokteran Universitas Mulawarman, olehkarenanya fakultas memberikan terobosan dalam membuat log book kegiatan pembelajaran mahasiswa dan juga prestasi baik akademik maupun non akademik kedalam bentuk digital yakni menerapkan pada platform e-portofolio hal ini di harapkan sebagai bentuk mendidik sumber daya manusia agar dapat berkontribusi dalam menghasilkan manusia berkualitas yang memiliki kemampuan berpikir kritis, kreatif, komunikasi serta berkolaborasi. Metode yang digunakan dalam pengabdian masyarakat ini berupa pembuatan buku panduan penggunaan e-portofolio beserta video tutorial. Perangkat tersebut kemudian di sosialisasikan kepada seluruh dosen dan mahasiswa Angkatan 2021 – 2022 yang berjumlah Hasil dari sosialisasi kepada mahasiswa didapatkan peningkatan pengetahuan pemanfaatan e-portofolio di Fakultas Kedokteran Universitas Mulawarman dengan nilai signifikansi sebesar 0.000.
EFEK DIET RENDAH KARBOHIDRAT TINGGI PROTEIN MENURUNKAN KADAR INSULIN PADA TIKUS MODEL SOPK-RESISTENSI INSULIN Hany Puspita Aryani
JPK : Jurnal Penelitian Kesehatan Vol. 10 No. 1 (2020): Juni
Publisher : Sekolah Tinggi Ilmu Kesehatan Katolik St. Vincentius a Paulo Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54040/jpk.v10i1.181

Abstract

Sindrom ovarium polikistik (SOPK) merupakan adanya gangguan metabolik dan sistem endokrin, ditemukan kejadian SOPK pada wanita usia reproduksi 5% - 10% di dunia. Wanita SOPK sering dijumpai pada wanita dengan kelebihan berat badan sebanyak 33% - 38%. Perubahan pola makan mengkonsumsi tinggi kalori memicu resistensi insulin (RI) memperparah keadaan SOPK. Tujuan penelitian ini mengetahui efek diet rendah karbohidrat tinggi protein (RKTP) terhadap penurunan kadar insulin pada model SOPK -RI. Penelitian true eksperimen laboratorik post test only control design yang dibagi menjadi tiga kelompok; Kelompok kontrol negatif (K- / tikus tanpa perlakuan diberi pakan standar); Kelompok kontrol positif (K+/ tikus model SOPK S-RI diberi pakan standar) dan Kelompok perlakuan (P/ tikus model SOPK diberi RKTP) selama 48 hari. Analisis yang digunakan adalah uji Anova dan Post Hoc, hasil penelitian nilai rata-rata, K- sebesar 18,21, K+ sebesar 12,66 dan P 13,7 analisis uji anova p = 0,001 menunjukkan ada perbedaan bermakna antara pemberian diet RKTP dengan kadar insulin p < 0,05. Hal ini terbukti diet RKTP dapat menurunkan kadar insulin sehingga diharapkan dapat mengurangi resiko infertilitas pada pasien SOPK.
Co-Authors Budi Santoso Elly Rustanti Ermawati Ermawati Karisma Dwi Ana Rahayu, Hanis Kusumawati Rista Dian Anggraini Sri Wulandari Sulistiawati Sylvie Puspita Warda Anil Masyayih Widjiati Widjiati Yoga Rosita Yoseph Copertino Tna’auni