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All Journal Paediatrica Indonesiana Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indian Journal of Forensic Medicine & Toxicology
Muhammad Faizi
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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Predispositions Factors Affecting Quality of Life in Children with T1DM During the Coronavirus Disease of 2019 Pandemic Nur Rochmah; Muhammad Faizi; Yuni Hisbiyah; Ike Wahyu Triastuti; Garindra Wicaksono; Anang Endaryanto; Soetjipto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17006

Abstract

Height-for-age in Children under 5 Years Old with Down Syndrome and Hypothyroidism Muhammad Faizi; Nur Rochmah; Yuni Hisbiyah; Anang Endaryanto; Soetjipto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17604

Abstract

Background: Children with Down syndrome tend to have accompanying comorbidities, such as hypothyroidism, and late detection of this ailment leads to reduced growth of the child. This study aimed to assess the growth patterns in children with Down Syndrome and hypothyroidism at diagnosis.Methods: This cross-sectional study was conducted from September to December 2020 with 56 subjects at the Pediatric Endocrine Outpatient Clinic of Dr. Soetomo Hospital. Diagnosis of Down Syndrome was confirmed by karyotyping, while the weights and heights were assessed using a standardized curve for children with Down Syndrome and then calculated using Peditools. Fifty-six children with Down Syndrome and hypothyroidism were included, comprising 32 boys and 24 girls (mean age, 37.75 ± 34.26 months). Majority of the subjects had normal weight, height, and Body Mass Index (36/56 [mean z-score, −1.62 ± 2.36], 33/56 [mean height-z-score, −0.43 ± 2.74], and 30/56 [mean z-score, −2.00 ± 2.06], respectively). Furthermore, the mean onset of diagnosis was 17.07 ± 32.23 months, where 23 out of the 56 children had short stature and had gotten diagnosed at over 12 months of age.Conclusion: From the results obtained, hypothyroidism can be said to be associated with reduced growth in children with DS.
Anaphylactic Shock Associated with Scratch Testing Ariyanto Harsono; Muhammad Faizi
Paediatrica Indonesiana Vol 36 No 11-12 (1996): November - December 1996
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.575 KB) | DOI: 10.14238/pi36.11-12.1996.258-64

Abstract

A 10-year old boy with bronchial asthma referred to allergy clinic for allergy work-up. He complained of abdominal pain and blurred vision 20-rmnutes after undergoing allergy skin scratch test. Physical examination showed clammy and cyano­tic extremities, and hypotension. The skin test result showed positive rection for house dust, mite, and shrimp. Based on these findings the diagnosis of anaphylaxis associ­ated with scratch test was made. The suggested offending extract was shrimp with possible interference of the other two extracts. Epinephnne 0.3 subcutaneously was initiated. The first dose gave a disappointing result, and then followed by the second dose which gave better result; dexamethasone was also administered. The eosinophilia, positive specific Ig E to shnmp, house dust and mite as indicated by RAST justify the atopic status of the patient. The management of the main disease consisted of house dust control, elimination diet, and symptomatic treatment were commenced.
Ethical aspects of gender assignment in ambiguous genitalia - congenital adrenal hyperplasia: a case report Nur Rochmah; Muhammad Faizi; Adwina Nurlita Kusuma Wardhani
Paediatrica Indonesiana Vol 61 No 6 (2021): November 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.6.2021.356-8

Abstract

Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder commonly caused by mutation of the CYP21A2 gene, resulting in deficiency of an enzyme required for cortisol synthesis in the adrenal cortex. In 90-95% of cases, the deficient enzyme is 21-hydroxylase (21-OH), with an incidence ranging from 1 in 5,000 to 15,000 live births across various ethnic and racial backgrounds. In classical 21-OH deficiency (21-OHD) CAH, excessive androgen exposure in the fetus results in virilization at birth.1 The management of ambiguous genitalia in children with CAH presents a unique and ethically challenging decision-making dilemma for the medical team. Insensitive and poorly informed statements made in the delivery room may cause long-term psychological problems for the families. It is important to refrain from assigning gender until sufficient diagnostic information can be gathered. Parents, as guardians, and the supporting medical team must make decisions on behalf of the child, with the goal of enabling the child to grow into a healthy and happy adult with his or her assigned gender.2,3 We report a case of a child with CAH, focusing on the ethical challenges in management of ambiguous genitalia.
FRUCTOSAMINE AND GLYCATED ALBUMIN IN PATIENTS WITH TYPE 1 DIABETES MELLITUS DURING RAMADHAN FASTING Vinzy Yulina; Sidarti Soehita; Muhammad Faizi; Budiono Budiono
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 23, No 2 (2017)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v23i2.1141

Abstract

Puasa Ramadhan dapat meningkatkan kebahayaan komplikasi di pasien Diabetes Melitus (DM) tipe 1, yang dapat dicegah dengankendali glikemik yang baik. Pemeriksaan fruktosamin dan albumin glikat digunakan untuk menggambarkan rerata kadar glukosa darahselama 2-3 minggu sebelumnya, sehingga lebih sesuai digunakan untuk menggambarkan kendali glikemik selama puasa Ramadhan(1 bulan). Tujuan penelitian ini adalah membandingkan dan membuktikan adanya kenasaban antara kadar fruktosamin dengan nilaialbumin glikat sebelum, pertengahan dan akhir bulan puasa Ramadhan di pasien DM tipe 1 di RSUD dr.Soetomo Surabaya. Penelitianini menggunakan desain analitik observasional di 13 pasien DM tipe 1 berusia 9–18 tahun yang menjalankan puasa Ramadhan.Pemeriksaan fruktosamin menggunakan metode nitroblutetrazolium (NBT) dengan alat Cobas Integra. Nilai albumin glikat dihitungsebagai persentase kadar albumin glikat (menggunakan metode enzimatik) terhadap kadar jumlah keseluruhan albumin serum(menggunakan metode bromcresol purple), dengan alat Proline R-910. Hasil dianalisis menggunakan uji statistik t-berpasangan dankenasaban Pearson. Tidak didapatkan perbedaan bermakna antara rerata kadar fruktosamin pertengahan dibandingkan sebelum(p=0,307), akhir dibandingkan sebelum (p=0,249) dan akhir dibandingkan pertengahan bulan puasa Ramadhan (p=0,362). Tidakdidapatkan perbedaan bermakna antara rerata nilai albumin glikat pertengahan dibandingkan sebelum (p=0,478), akhir dibandingkansebelum (p=0,285) dan akhir dibandingkan pertengahan bulan puasa Ramadhan (p=0,247). Kenasaban positif bermakna didapatkanantara kadar fruktosamin dan nilai albumin glikat sebelum (p=0,0001, r=0,952), pertengahan (p=0,0001, r=0,948) dan akhir bulanpuasa Ramadhan (p=0,0001 dan r=0,963). Kadar fruktosamin dan nilai albumin glikat dapat digunakan sebagai tolok ukur kendaliglikemik di pasien DM tipe 1 yang menjalankan puasa Ramadhan.
Co-Authors Adwina Nurlita Kusuma Wardhani Anang Endaryanto Ariyanto Harsono Budiono Budiono Garindra Wicaksono Ike Wahyu Triastuti Nur Rochmah Sidarti Soehita Soetjipto Vinzy Yulina Yuni Hisbiyah