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This Author published in this journals
All Journal Paediatrica Indonesiana Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indian Journal of Forensic Medicine & Toxicology
Muhammad Faizi
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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Journal : Paediatrica Indonesiana

 1 
Anaphylactic Shock Associated with Scratch Testing Ariyanto Harsono; Muhammad Faizi
Paediatrica Indonesiana Vol 36 No 11-12 (1996): November - December 1996
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.575 KB) | DOI: 10.14238/pi36.11-12.1996.258-64

Abstract

A 10-year old boy with bronchial asthma referred to allergy clinic for allergy work-up. He complained of abdominal pain and blurred vision 20-rmnutes after undergoing allergy skin scratch test. Physical examination showed clammy and cyano­tic extremities, and hypotension. The skin test result showed positive rection for house dust, mite, and shrimp. Based on these findings the diagnosis of anaphylaxis associ­ated with scratch test was made. The suggested offending extract was shrimp with possible interference of the other two extracts. Epinephnne 0.3 subcutaneously was initiated. The first dose gave a disappointing result, and then followed by the second dose which gave better result; dexamethasone was also administered. The eosinophilia, positive specific Ig E to shnmp, house dust and mite as indicated by RAST justify the atopic status of the patient. The management of the main disease consisted of house dust control, elimination diet, and symptomatic treatment were commenced.
Ethical aspects of gender assignment in ambiguous genitalia - congenital adrenal hyperplasia: a case report Nur Rochmah; Muhammad Faizi; Adwina Nurlita Kusuma Wardhani
Paediatrica Indonesiana Vol 61 No 6 (2021): November 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.6.2021.356-8

Abstract

Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder commonly caused by mutation of the CYP21A2 gene, resulting in deficiency of an enzyme required for cortisol synthesis in the adrenal cortex. In 90-95% of cases, the deficient enzyme is 21-hydroxylase (21-OH), with an incidence ranging from 1 in 5,000 to 15,000 live births across various ethnic and racial backgrounds. In classical 21-OH deficiency (21-OHD) CAH, excessive androgen exposure in the fetus results in virilization at birth.1 The management of ambiguous genitalia in children with CAH presents a unique and ethically challenging decision-making dilemma for the medical team. Insensitive and poorly informed statements made in the delivery room may cause long-term psychological problems for the families. It is important to refrain from assigning gender until sufficient diagnostic information can be gathered. Parents, as guardians, and the supporting medical team must make decisions on behalf of the child, with the goal of enabling the child to grow into a healthy and happy adult with his or her assigned gender.2,3 We report a case of a child with CAH, focusing on the ethical challenges in management of ambiguous genitalia.
Co-Authors Adwina Nurlita Kusuma Wardhani Anang Endaryanto Ariyanto Harsono Budiono Budiono Garindra Wicaksono Ike Wahyu Triastuti Nur Rochmah Sidarti Soehita Soetjipto Vinzy Yulina Yuni Hisbiyah