Article Per Year (5 Year)
p-Index From 2019 - 2024
1.756
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Syiah Kuala International Journal of Integrated Health Sciences Pharmaciana: Jurnal Kefarmasian Media Ilmu Keolahragaan Indonesia Buletin Farmatera Jurnal Keperawatan dan Fisioterapi (JKF) JURNAL FARMASIMED (JFM) IJOEP : International Journal of Ecophysiology
Yamamoto, Zulham
Department Of Histology, Faculty Of Medicine, Universitas Sumatera Utara
Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology Other

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Media Ilmu Keolahragaan Indonesia

 1 
Effect of Exercise Intensity in Glut4 Expression on Type 2 Diabetes Mellitus Rat Rahmi, Rahmi; Machrina, Yetty; Yamamoto, Zulham
Media Ilmu Keolahragaan Indonesia Vol 11, No 2 (2021): December 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/miki.v11i2.34222

Abstract

Glucose transporter4 (GLUT4) is the main glucose transporter in skeletal muscle. Impaired GLUT4 expression plays a role in the disorders of glycemic homeostasis such as Type- 2 Diabetes Mellitus (T2DM). Exercise can increase the GLUT4 expression in skeletal muscles so that glucose can get into the cells faster. The intensity of exercise is an important factor in reducing blood glucose levels in patients with T2DM. This study used stored biological material of gastrocnemius muscle from 15 T2DM models of Wistar rats. Rats were divided into three treatment groups namely P0 (no exercise, control), P1 (moderate-intensity continuous exercise), and P2 (vigorous-intensity continuous exercise), and treated for 8 weeks. Glut4 expression was determined by real time-PCR. The relative expression of the Glut4 gene was calculated using the Livak formula. Moderate-intensity exercise increased Glut4 expression by 2.39 times while vigorous-intensity exercise increased Glut4 expression 2.56 times compared to control. The vigorous-intensity continuous exercise expressed higher Glut4 expression than the moderate- intensity continuous one.
Co-Authors Bambang Prayugo Bayu Dewanto Dina Rahmi Solihad Nasution Evirosa Juliartha Simanjuntak Gembira Arkemo Situmorang Ismatul Fauziah Rambe Jelita Siregar Kevin Kevin Lita Feryawati M. Ichwan Muhammad Ichwan Muhammad Ichwan Novrina Situmorang Nuraiza Meutia Rahmi Rahmi Syahfira A Syahna Yetty Machrina