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Tri Wijayanti
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology

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Aktivitas Hepatoprotektif Ekstrak Daun Sukun (Artocarpus altilis (Park.) Fsb.) pada Mencit Balb/C yang Diinduksi Vaksin Hepatitis B TRI WIJAYANTI; VIVIN NOPIYANTI; IKA PURWIDYANINGRUM
Jurnal Farmasi Indonesia Vol 10 No 2 (2013): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (618.631 KB) | DOI: 10.31001/jfi.v10i2.710

Abstract

Breadfruit leaves (Artocarpus altilis (Park.) Fsb.) is a medicinal plant that is thought to have potential as a hepatoprotective. In the community itself has been widely used and is reported to have many uses since it contains efficacious compounds in plants such as saponins, polyphenols, tannins, hydrocyanic acid, acetylcholine, riboflavin and flavonoids. This study aimed to determine the hepatoprotective effect of breadfruit leaves extract in mice induced by hepatitis B vaccine with the percentage of liver cell necrosis as parameter. Breadfruit leaves extract was made by percolation method with ethanol 70% as the solvent. The animal test was induced by hepatitis B vaccine, then they was grouped into 5 groups of negative control group were given CMC 1%, the positive control group were given Echinacea (Imboost®) and the treatment group of test animals were given breadfruit leaf extract at a dose 750 mg/kgBW, 1200 mg/kgBW, 1650 mg/kgBW. Hepatoprotective effect was observed by liver necrosis parameter on histopathologic liver mice preparations at day 35 after treatment. The results showed that the breadfruit leaf extract can provide hepatoprotective effect by reduction the liver necrosis. The percentage of reduction necrosis of the liver in the treatment of 70% ethanol extract of breadfruit leaves dose of 1200 mg/kgBW provides the most effective hepatoprotective effect on male mice induced hepatitis B vaccine.
Analisis Pengendalian Persediaan Obat Kategori Av Dengan Metode Abc, Ven Dan Eoq Di Instalasi Farmasi Rumah Sakit Aura Syifa Kediri Chandra Arifin; Tri Wijayanti; Gunawan Pamudji Widodo
Jurnal Farmasi Indonesia Vol 20 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v20i1.1086

Abstract

ABSTRACT Inventory Control Analysis Of AVMedicine CategoriesbyABC, VEN and EOQ Method In Pharmacy Installation at Aura Syifa Hospital Kediri.Pharmaceutical logistics management and pharmaceutical services aim to identify, prevent and resolve drug-related problems. Broadness of services and Aura Syifa Hospital Kediri participation in Jaminan Kesehatan Nasional (JKN) requires an efficient pharmaceutical supplies management. Regulations changes in Badan Penyelenggara Jaminan Sosial (BPJS) regarding tiered referral also change the pattern of drug consumption. In addition, arrears of BPJS patient claim payment at Aura Syifa Hospital Kediri during the last few months caused hospital to be slightly constrained in terms of operations and services, especially related to the procurement of medicines. Purpose of this study was to analyze control system and improve the efficiency of managing AV classification medicine using ABC, VEN and EOQ methods inpharmacy installation at Aura Syifa Hospital Kediri.This study wasdescriptive with retrospective data collected, data used in the period January 2018 - December 2018. Medicine analyzed were oral drugs, injections and infusions that were included in group A from the results of ABC analysis, group V from the results of VEN analysis so it was obtained BPJS medicine AV categories. Result of this study were combination of ABC and VEN analysis methods could identify drugs that require strict inventory control and prioritize 12 BPJS medicine in AV category. Pharmacy installation at Aura Syifa Hospital Kediri in 2018 did not meet cost efficiency that is: procurement frequency was higher than the EOQ method. Calculation of ABC, VEN and EOQ methods may improve efficiency in controlling AV classification medicine supplies in BPJS patients at IFRS Aura Syifa Kediri.
Co-Authors Afi Rahmat Slamet Chandra Arifin Gunawan Pamudji Widodo Muhammad Mansur PURWIDYANINGRUM, IKA Vivin Nopiyanti