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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JPSCR : Journal of Pharmaceutical Science and Clinical Research FITOFARMAKA: Jurnal Ilmiah Farmasi Jurnal Ilmiah Mandala Education (JIME) Jurnal Farmasi Indonesia JISIP: Jurnal Ilmu Sosial dan Pendidikan Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pharma Bhakta
Gunawan Pamudji Widodo
aculty of Pharmacy, Universitas Setia Budi, Surakarta 57127, Indonesia
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Evaluasi Perencanaan dan Pengadaan Kebutuhan Obat Publik Serta Ketersediaan Obat di Wilayah Kerja Dinas Kesehatan Daerah Kota Tomohon Tahun 2016 Haris Maspekeh; Satibi; Gunawan Pamudji Widodo
Jurnal Farmasi & Sains Indonesia Vol 1 No 2 (2018)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

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Abstract

Ketidakmampuan merencanakan kebutuhan obat dengan baik di tingkat Puskesmas, akan berpengaruh pada persediaan obat. Tujuan dari penelitian ini untuk mengetahui kesesuaian perencanaan, pengadaan kebutuhan obat publik dan tingkat ketersediaan obat dengan indikator efisiensi dan efektifitas pengelolaan obat serta permasalahan yang terjadi dalam perencanaan dan pengadaan kebutuhan obat publik di wilayah kerja dinas kesehatan daerah kota tomohon tahun 2016. Rancangan penelitian deskriptif. Data diperoleh melalui pengamatan dokumen obat tahun 2016, obat Indikator sebanyak 144 item obat, serta wawancara dengan pengelola obat, Kepala Puskesmas, Kepala Instalasi Farmasi Kota Tomohon dan Sekretaris Dinas Kesehatan Daerah Kota Tomohon. Data yang diperoleh dianalisis dengan indikator efisiensi dan efektifitas pengelolaan obat menggunakan indikator Depkes dan dibandingkan dengan standar atau hasil penelitian lain. Hasil yang tidak sesuai standar yaitu rata-rata perencanan obat yang tepat di puskesmas wilayah kerja Dinas Kesehatan Daerah Kota Tomohon adalah sebesar 33,35%, kurang tepat sebesar 48,03% dan berlebih sebesar 18,62%. Persentase alokasi dana pengadaan obat di IFK sebesar 3,91%. Rata-rata persentase kesesuaian antara pengadaan dengan kenyataan pakai obat 94,98%. Frekuensi pengadaan IFK 1 kali setahun. Hasil yang sesuai standar yaitu rata-rata persentase kesesuaian item obat yang tersedia sebesar 94,33%. Rata-rata persentase penyimpangan perencanaan 5,66%. Persentase ketersediaan dana pengadaan obat di IFK tahun 2016 sebesar 100%. Tidak pernah terjadi kesalahan faktur. Rata-rata lama waktu pembayaran dari dinas kesehatan kepada distributor adalah 50 hari dengan rata-rata lama waktu pembayaran yang disepakati yaitu 60 hari. Rata-rata tingkat ketersediaan obat kategori kurang sebesar 5,97%, aman sebesar 76,88%, dan berlebih sebesar 17,15%. Prioritas penanganan masalah sebagai berikut: 1). Menyusun Standar Operasional Prosedur pengelolaan obat. 2). Membentuk Tim Perencanaan Obat Terpadu Kabupaten/Kota. 3). Menyelenggarakan pelatihan tentang pengelolaan obat. 4). Menerapkan Sistem Informasi Manajemen (SIM) pengelolaan obat.
ANALISIS PELAKSANAAN STANDAR PELAYANAN MINIMAL RUMAH SAKIT BIDANG FARMASI DI INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH DR. ABDUL AZIZ SINGKAWANG Dini Okyaviani; Tri Murti Andayani; Gunawan Pamudji Widodo
Jurnal Farmasi & Sains Indonesia Vol 2 No 2 (2019)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

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Abstract

Rumah Sakit Umum Daerah dr. Abdul Aziz Singkawang sebagai Badan Layanan Umum Daerah (BLUD) perlu melakukan pengukuran tentang pencapaian indikator-indikator Standar Pelayanan Minimal Rumah Sakit yang telah ditetapkan. Penelitian ini bertujuan untuk mengetahui gambaran pelaksanaan Standar Pelayanan Minimal Rumah Sakit bidang farmasi di Instalasi Farmasi RSUD dr. Abdul Aziz Singkawang yaitu meliputi waktu tunggu pelayanan obat, tidak adanya kejadian kesalahan pemberian obat, kepuasan pelanggan dan penulisan resep sesuai formularium. Penelitian ini merupakan penelitian non eksperimental deskriptif dengan menggunakan metode pendekatan secara kualitatif dan kuantitatif. Penelitian dilakukan selama 1 bulan pada bulan Desember 2016. Data penelitian dikelompokkan menjadi data kualitatif dan kuantitatif. Data Kualitatif berupa wawancara mendalam dengan Kepala Instalasi Farmasi, karyawan, dokter sedangkan data kuantitatif berupa observasi dan kuesioner kepada pasien rawat jalan. Data hasil penelitian dianalisis secara deskriptif dengan rumus perhitungan yang sesuai. Hasil penelitian didapatkan rata-rata waktu tunggu pelayanan resep jadi 18, 42 menit, resep racikan 40,37 menit, tidak adanya kesalahan pemberian obat 100%, kepuasan pelanggan 96,47%, penulisan resep sesuai formularium 95,95%. Dapat disimpulkan untuk waktu tunggu pelayanan obat, tidak adanya kejadian kesalahan pemberian obat dan tingkat kepuasan pelanggan terhadap pelayanan farmasi telah memenuhi standar namun untuk kesesuaian penulisan resep dengan formularium belum memenuhi standar. Faktor yang mempengaruhi pelaksanaan Standar Pelayanan Minimal yaitu keterbatasan SDM, peresepan dokter terhadap obat-obat diluar formularium, sarana dan prasarana yang belum optimal, sosialisasi formularium belum optimal dan Kebijakan dalam pelayanan resep untuk menghindari kejadian kesalahan pemberian obat.
EVALUASI TINGKAT KESESUAIAN STANDAR AKREDITASI TERHADAP PELAYANAN FARMASI DAN STRATEGI PERBAIKAN DENGAN METODE HANLON DI RSUD KABUPATEN BIMA Dedent Eka Bimmaharyanto.s; Achmad Fudholi; Gunawan Pamudji Widodo
Jurnal Ilmiah Mandala Education (JIME) Vol 3, No 2 (2017): Jurnal Ilmiah Mandala Education (JIME)
Publisher : Lembaga Penelitian dan Pendidikan Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.19 KB) | DOI: 10.36312/jime.v3i2.255

Abstract

Getting maximal service represent dream all society especially receiver of service of  the hospital  including in pharmacy installation. Patient got many problems because service not yet fulfilled standard. To fulfill requirement of patient, pharmacy installation have to this research accredit  to know storey level according to seven accreditation standard to service of pharmacy in RSUD Sub Province Bima and repair strategy with Hanlon method.  This Research use instrument of quizioner  Depkes and special informan interview counted 15 informan and people lock counted 3 people. Subject at this research is all officer in concerned and have important role in pharmacy Installation RSUD Sub Province Bima. Conducted by assessment seven standard  later then compared to between informan with result of observation,  afterwards analyzed by strategy development by using Hanlon method. Result of Research of show there are difference of result assessment of standard accredit between officer of pharmacy Installation that is ( 58,75%) with research that is  ( 55%). From seventh of accreditation standard, nothing that fulfill accreditation standard (< 60%), result  strategy development with Hanlon method is Facility and equipments, repair of facilities and basic facilities of Pharmacy administration  management and, immediately do function KFT . Evaluation and quality control, require to make pharmacy program written  and also SK about meeting schedule .Philosophy   and  target, SK about policy of pharmacy service  from  Hospital head. Policy and procedure, making SOP and policy written  about management of provisions of pharmacy . Development of education program and staff,  done by education program and periodical training in IFRS. STAF and head, existence of staff pharmacy performance evaluation and orientation to officer of Installation Pharmacy
EVALUASI PERENCANAAN KEBUTUHAN OBAT PUBLIK SERTA KETERSEDIAAN OBAT DI TINGKAT PUSKESMAS SE-WILAYAH KERJADINKES KOTA SURAKARTATAHUN 2015 Eko Yudha Prasetyo; Satibi .; Gunawan Pamudji Widodo
Jurnal Farmasi Indonesia Vol 13 No 2 (2016): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (658.166 KB) | DOI: 10.31001/jfi.v13i2.289

Abstract

Drug planning is an important aspect of drug management. Planning is aimed at determining the type and amount of drug in accordance with the needs of community helth center. Although the regulatory guideline of public drug management have been made, but still found the incidence of overstock and stockout. With these considerations it’s necessary to evaluate related planning processes and drug availability. The purpose of this study to know the planning process, the problems encountered and the level of drug availability in community health center throughout the whole working area of Surakarta Department of Health. This research is observational and evaluative study with qualitative approach, supported by quantitative data. Secondary data were obtained from the search document of drug plan for 2015, the usage and demand report of drug. The secondary data is processed to determine the accuracy of planning, the availability and suitability of drug demand. To strengthen information were conducted triangulation and interviews with drug manager related. The results showing the drug plan has not been efficient seen from an average accuracy of drug planning in treatment primary health centers is 440.5% and 389.98% at non-treatment primary health centers. The problems in planning isn’t optimal use of information management system based on electronically in providing data for drug planning, the procurement with e-purchasing requires time and administration are too long, the plan of medicine isn’t fully realized, the community health center received drug beyond the plan so that the use of drugs less effective, The average availability of drugs in the category of excess which amounted to 31.13 months in treatment health centers and 33.95 months in non-treatment.
EFFECT OF KNOWLEDGE LEVEL TO QUALITY OF LIFE WITH DRUG USE COMPLIANCE AS INTERMEDIATE VARIABLE AT RHEUMATOID ARTHRITIS PATIENTS IN OUTPATIENT PHARMACY DEPO Dr. MOEWARDI HOSPITAL SURAKARTA Rahmadani .; Chairun Wiedyaningsih; Gunawan Pamudji Widodo
Jurnal Farmasi Indonesia Vol 13 No 2 (2016): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (503.237 KB) | DOI: 10.31001/jfi.v13i2.290

Abstract

Prevalensi rheumatoid arthritis di berbagai negara termasuk Indonesia meningkat sejalan dengan perubahan gaya hidup seperti asupan makanan, obesitas, kurangnya aktivitas fisik, dan obat-obatan. Peningkatan pengetahuan dan kepatuhan penggunaan obat diharapkan dapat mempengaruhi peningkatan kualitas hidup pasien rheumatoid arthritis. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh tingkat pengetahuan terhadap kualitas hidup dengan kepatuhan penggunaan obat sebagai variabel antara. Penelitian menggunakan metode cross sectional, dengan survey untuk melihat pengaruh tingkat pengetahuan terhadap kualitas hidup dan kepatuhan penggunaan obat sebagai variabel antara. Penilaian pengetahuan menggunakan ACREU RAKQ, penilaian kepatuhan menggunakan MMAS-8 dan penilaian kualitas hidup menggunakan The AIMS2-SF. Data yang diambil adalah data tingkat pengetahuan, kepatuhan penggunaan obat dan kualitas hidup dengan menggunakan kuesioner dan data dianalisis menggunakan path analysis. Subyek yang diperoleh dalam penelitian sejumlah 30 pasien rheumatoid arthritis. Hasil kuesioner tingkat pengetahuan yaitu didapatkan 13 responden (43,33%) yang memiliki pengetahuan tinggi. Hasil kuesioner kepatuhan penggunaan obat yaitu didapatkan 14 responden (46,67%) yang memiliki kepatuhan sedang. Hasil kuesioner kualitas hidup yaitu didapatkan 16 responden (53,33%) yang memiliki kualitas hidup sedang. Pengaruh signifikan antara tingkat pengetahuan terhadap kualitas hidup dengan kepatuhan penggunaan obat sebagai variabel antara dengan nilai estimasi atau besaran persentase pengaruh 79%, artinya kepatuhan penggunaan obat berpengaruh signifikan.
Aktivitas Antitusif Dan Ekspektoran Ekstrak Etanol, Fraksi Polar-Semi Polar Herba Meniran (Phyllanthus niruri L.) Pada Marmut (Cavia porcellus) Fakhruddin Fakhruddin; Arief Nurrochmad; Gunawan Pamudji Widodo
Jurnal Farmasi Indonesia Vol 14 No 2 (2017): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (426.559 KB) | DOI: 10.31001/jfi.v14i2.296

Abstract

Phyllantus niruri L., is wild plants, has wide applications in traditional medicine. The purpose of this study is to evaluated antitussive, expectorant activity, and description antitussive mechanism of phyllantus herbs. Test animal male guniea pigs as many as 36 divided into 9 groups each consisting of 4 guinea pigs. The antitussive activity of ethanol extract and polar-semi-polar fraction be observed on percentage cough suppression by giving a citric acid 7.5% for 5 days. The Expectorant activity was evaluated with phenol red concentration in guinea trachea on 7 days. The mechanism description is evaluated by looking at the comparison of phyllantus herbs and combination ethanol extract phyllantus herbs and codeine modulated by the opioid receptor and glibenclamide modulated by the ATP sensitiv.e K+ channel. The research showed ethanol extract and polar-semi-polar fraction increased the suppression of citric acid induced by citric acid 7.5% and decreased the a supprssant of mucus secretion on evaluation of expectorant. Polar-semi-polar fraction 160 mg/kgBB showed the effective activity antitussive 63,57%. Polar-semi-polar fraction 80 mg/kgBB showed decreased phenol red secretion by 56,91%. This study provides evidence that phyllantus herbs can be used as an antitussive and a suppressant of mucus secretion. Phyllantus herbs not description on mechanism antitussive modulated by the opioid receptor and ATP sensitiv.e K+ channel. The antitussive mechanism may be modulated by other systemic nerves and peripheral nerves
Efek Ekstrak Etanol Daun Kelor (Moringa oleifera, Lamk.) Pada Mencit Model Demensia: Kajian Memori Spasial, Kadar Malondialdehid Dan Jumlah Sel Piramidal Hipokampus Area CA1 Dan CA2-CA3 arikha ayu susilowati; Gunawan Pamudji Widodo; Jason Merari
Jurnal Farmasi Indonesia Vol 16 No 2 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (868.86 KB) | DOI: 10.31001/jfi.v16i2.612

Abstract

ABSTRACT Dementia is a disease of nerve cells in the brain, due to the hippocampus damaged by free radicals. EEDK (Ethanol extract of kelor leaves)(Moringa oleifera, Lamk.) contains phytochemicals, carotene, vitamins, minerals, amino acids, flavonoids and phenolics, proven to reduce oxidative damage and memory deficits. This study aims to determine the effect of EEDK on spatial memory, MDA levels, the number of hippocampal pyramidal cells damaged in the CA1, CA2-CA3 area and histopathological features of mice. The design of this study was pre-test and post-test control group design for spatial memory test and post test control group design for MDA levels, hippocampal pyramidal cell counts and histopathological features. This Reseach using 30 mice divided into of 6 groups, each group consist of 5 mice, namely the normal control group, positive control, negative control, EEDK group 100, 200, and 400 mg/kg body weight, all groups induced by Pb acetate 50 mg / KgBB except the normal group. Positive control was treated with quercetin 50 mg/kgBB, while negative controls were not treated. Memory test data obtained from the Morris water maze pre and post-test, antioxidant status data obtained from MDA levels and histopathological data obtained from the calculation of pyramidal cell counts. Data analysis used repeated measures ANOVA and ANOVA with Post Hoc LSD. The results showed that latency time, MDA level test and brain histopathology examination had significant differences between the negative control group and the EEDK group. EEDK 400 mg/kgBB was most effective in improving spatial memory, decreasing MDA levels, and preventing damage to the hippocampal pyramidal cell CA1, CA2-CA3 area.
Uji Aktivitas Diuretik Ekstrak n-Heksana Daun Ceplukan (Physalis angulata L.) pada Tikus (Rattus norvegicus) Jantan Wistar INDRAWATI FITRIANA; AGUNG ENDRO NUGROHO; GUNAWAN PAMUDJI WIDODO
Jurnal Farmasi Indonesia Vol 9 No 1 (2012): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1009.524 KB) | DOI: 10.31001/jfi.v9i1.714

Abstract

Ceplukan (Physalis angulata L.) empirically have diuretic effect. This study aimed to determined the diuretic effect of n-hexane extract of ceplukan leaves on Wistar male rats. Ceplukan leaves powder were extracted by maceration with n-hexane solvent. Test animal was used 25 Wistar male rats were divided into 5 groups: group I were given CMCNa 0.5% (negative control), group II (positive control) were given furosemide dose 4.32 mg/200 g BW, group III, IV, V were given n-hexane extract suspension dose of 375, 187.5, 93.75 mg/200 g BW respectivelly. The urine volume were measured in hours-6, 12, 18 and 24. Diuretic effect is obtained by calculating the cumulative urine volume and AUC (Area Under the Curve). The data obtained were analyzed by one way ANOVA with a level of 95% significant, then test by LSD (Least Significant Difference).The results showed that n-hexane extract of ceplukan leaves had diuretic effect. The effective dose of n-hexane extract of ceplukan leaves for diuretic effect was dose 375 mg / 200 g BW.
Uji Sitotoksik Fraksi n-Heksana, Etil Asetat, Etanol dari Ekstrak Etanolik Daun Ende (Coccinia grandis (L.) Voigt) pada Sel HeLa NURAINI HARMASTUTI; GUNAWAN PAMUDJI WIDODO; MARIA E.D.O. HUREK MAKING; MARIA YANGSYE LENGGU; FEOLISTIN MIENCE POBAS
Jurnal Farmasi Indonesia Vol 9 No 1 (2012): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1009.178 KB) | DOI: 10.31001/jfi.v9i1.725

Abstract

Ende leaf (Coccinia grandis (L.) Voigt) is the one of plant that most popular in Nusa Tenggara Timur province. The study was aimed to know the cytotoxic effect of n-hexane, ethyl acetate, and ethanol fractions from ethanolic extract of ende leaf on hela cell and its IC50 value. Dried ende was macerated with 96 % ethanol solvent, then it was fractionated by n-hexane, ethyl acetate, and ethanol solvent. Then it was tested the cytotoxic by MTT (Microculture Tetrazolium Salt) method on HeLa cell The absorbance response was converted into abbreviation of cell viability. IC50 value was calculated with linear regression equation between logarithm of concentration samples versus percentage viability of HeLa cell. The result showed that the cytotoxic test of ende leaf against HeLa cell presented the IC50 value of ethanolic extract and n-hexane, ethyl acetate, and ethanol fractions were 415.719 ppm; 307.142 ppm; 50303.71 ppm; dan 50722.424 ppm, respectively.
DEVELOPMENT STRATEGY OF PHARMACY DEPARTEMENT BASED ACCREDITATION EVALUATION IN RSUD Dr MOEWARDI SURAKARTA BY HANLON METHOD Ade Sukma Hamdani; Asri Laksmi Riani; Gunawan Pamudji Widodo
JISIP: Jurnal Ilmu Sosial dan Pendidikan Vol 1, No 2 (2017): Volume 1 Nomor 2 JISIP: Jurnal Ilmu Sosial dan Pendidikan
Publisher : Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (415.099 KB) | DOI: 10.36312/jisip.v1i2.176

Abstract

Getting excellent service is the dream of all society, especially recipients of health services in the hospital including in pharmacy departement. Many problems obtained by the patient, because services do not meet the standards. To meet the needs of the patient, pharmacy departement must be accredited. The purpose this study was to determine the suitability of pharmacy departement service to accreditation standards in RSUD Dr Moewardi Hospital Surakarta and development strategy  based on Hanlon method. The research was a non experimental research plan. The data collected by using a self-assessment questionnaire of pharmacy care standards. The respondents consisted of key informant was the Hospital Director, Sub Division Head of Human Resources and Training, Head of Organization and Personnel, and the pharmacist in charge, and key informants that pharmacists and pharmaceutical technical employee in pharmacy installation hospital, and the main informant were all pharmacists and pharmacy technical staff of pharmacy installation hospital in Dr Moewardi Hospital Surakarta. From the results count of respondent of pharmacy installation officers, equalled with observation result. The processing of research data conducted with Hanlon method. The results showed that was difference in accreditation standard assessment between self-assessment of pharmacy installation hospital staff (97,5%) with the observation results (93,75%). From this result, the pharmacy installation of Dr Moewardi Surakarta had to meet KARS accreditation standards but still need to be maximized again to lead to JCI accreditation standard. Therefore, it was needed the commitment of Director, Accreditation Committee, Stakeholders and pharmacy installation hospital staffs in improving services in accordance with standards. Strategy and plan development efforts could be done through the addition of pharmacy staff, provision of space/place which meet the standards, complete SOP, optimal pharmaceutical care and evaluated and followed up
Co-Authors Abdul Mahmud Yumassik Achmad Fudholi Ade Sukma Hamdani Agung Endro Nugroho Arief Nurrochmad arikha ayu susilowati Asri Laksmi Riani Astri Aslam Chairun Wiedyaningsih Chandra Arifin Daniel Maharai Dedent Eka Bimmaharyanto.s Dian Marlina Dini Okyaviani Eko Yudha Prasetyo Endang Diyah Ercis Ercis FEOLISTIN MIENCE POBAS Ferdinan Jalung Handi Mukti Fahrizal Haris Maspekeh Hasty Martha Wijaya INDRAWATI FITRIANA Jason Merari Peranginangin MARIA E.D.O. HUREK MAKING MARIA YANGSYE LENGGU Milda Rianty Lakoan Muhamad Aulia Putra Tawakal Nur Aeni Hartih NURAINI HARMASTUTI Oetari Oetari Rahmadani . Rina Herowati Rosa Juwita Hesturini Satibi Satibi . Satibi Satibi Sri Fitrianingsih Tri Murti Andayani Tri Wijayanti Valiandri Puspadina Wirdah Wati R.