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All Journal Indonesia Chimica Acta Indonesian Journal of Fundamental Sciences
Lestari, Mega Fia
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Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Physics

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Identification of Anticancer and Antioxidant Potentials of Katang-Katang Flower Extract (Ipomea pes-caprae Linn) with Water Solvent Tamuddin, Yusriadi; Utami, Hermin Hardyanti; Husna, Saadatul; Lestari, Mega Fia; Salawali, Rismul Trianto; Towolioe, Sherly; Aras, Neny Rasnyanti M; Trifany, Andi Wahyu; Papriani, Nada Pertiwi
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 16, No 2: December 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v16i2.25353

Abstract

Cancer is a group of deadly diseases that attack human organs with an increasing number of cases and an increasing number of deaths from year to year. Free radicals as unstable molecules are one of the triggers for the emergence of cancer. Katang-katang or I. pes-caprae L. is a plant that could be found on almost all tropical coasts. So it has the potential to be developed as herbal medicine. This study used Flowers of I. pes-caprae L. as the research sample. This study aimed to identify the anticancer and antioxidant potential of the flower extract of I. pes-caprae L extracted with water as a solvent. This research included the phytochemical test of secondary metabolites, identification of anticancer potential based on the toxicity test using the Brine Shrimp Lethality Test (BSLT), and the antioxidant activity test using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The results showed that the flower extract of I. pes-caprae L. from water solvent contained active compounds including alkaloids, flavonoids, tannins, saponins, and terpenoids. The extract also has the potential as an anticancer with an LC50 value of 170.8441 ppm and strong antioxidant activity with an IC50 value of 71.7895 ppm.
Synthesis of Smart Packaging Based on Chitosan-PVA/Binahong Extract as an Antibacterial Plastic Aras, Neny Rasnyanti M; Lestari, Mega Fia; Irwana, Adinda
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 17, No 1: June 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v17i1.31419

Abstract

Chitosan-PVA composite with the addition of binahong extract is a bioplastic that is being developed aims to make eco-friendly product and contain antibacterial agents. This bioplastic is useful as packaging to maintain the freshness quality of food. The purpose of this research is to study and develop smart packaging with the addition of binahong leaf extract as an antibacterial agent. The manufacture of plastic in this study was carried out by varying the addition of binahong leaf extract ranging from 60-100%. The characteristics of the chitosan-PVA plastic were tested through FTIR, water uptake, and antibacterial tests. Chitosan-PVA plastic with the addition of 100% concentration of binahong extract had a good bacterial inhibition of 12 mm. The resulting chitosan-PVA plastic with binahong extract showed the presence of chemical bonds between the chitosan, PVA and flavonoid groups. The bioplastics produced have quite a large water uptake compared to non-biodegradable commercial packaging, reaching 491.52% with the addition of 90% binahong extract with the best antibacterial capabilities in the packaging with the addition of 100% binahong extract.
RELATIONSHIP ANALYSIS OF SHRINKAGE LEVEL, MOISTURE CONTENT, AND DRYING RATE OF EUCHEUMA COTTONII SEAWEED IN VARIOUS DRYING TIME AND METHODS Lestari, Mega Fia; Aras, Neny Rasnyanti M
Indonesian Journal of Fundamental Sciences Vol 10, No 1 (2024) Article in Press
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/ijfs.v10i1.60737

Abstract

In this study, shrinkage level, moisture content, and drying rate of Eucheuma cottonii seaweed were compared using various drying times and methods. Both sun and wind drying were employed, with drying times ranging from 0 to 240; 480; 720; and 960 minutes for each method. In Pajukukang Subdistrict, Bantaeng Regency, Eucheuma cottonii seaweed was harvested and dried using a variety of drying methods. The findings indicated that the Pajukukang Subdistrict was extremely hot, with the greatest temperatures and relative humidity readings of 52.4 oC and 47% RH (sun drying) and 32.6 oC and 55% RH (wind drying). The seaweed also changed after drying, going from a fresh brown color to a deeper brown color with an extremely dry physical shape (sun drying) and dry with white spots all over its surface (wind drying). Additionally, when drying time increases, shrinkage level increases. On a wet and dry basis, however, the converse occurred, where the two types of moisture content dropped as the drying time increased. When the drying time increases for both drying processes, a phenomena known as a falling rate period happens for the relationship between the drying rate and the moisture content on a dry basis.
Co-Authors Aras, Neny Rasnyanti M Husna, Saadatul Irwana, Adinda Papriani, Nada Pertiwi Salawali, Rismul Trianto Tamuddin, Yusriadi Towolioe, Sherly Trifany, Andi Wahyu Utami, Hermin Hardyanti